Hypophosphite mediated carbon-carbon bond formation: A clean approach to radical methodology

Tetrahedron Letters

Volumn 40, Issue 12, 1999, Pages 2415-2416

  Graham, Stephen R ^a   Murphy, John A ^a   Coates, David ^b  

^a UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^b Merck Sharp & Dohme Limited   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON; HYPOPHOSPHOROUS ACID; PHOSPHITE; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; CHEMICAL BOND; CYCLIZATION; HALOGENATION; NEUROTOXICITY; OXYGENATION; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; SYNTHESIS;

EID: 0033583001     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(99)00117-3     Document Type: Article

References (13)

1. 1. S. R. Graham, J. A. Murphy and D. Coates, European Patent Application No. 98115971.8
2. 2. W. B. Motherwell and D. Crich, Free Radical Chain Reactions in Organic Synthesis, Academic Press, London. 1992
3. 3. (a) J. Light and R. Breslow, Org. Synth., 1995, 72, 199
4. (b) J. Light and R. Breslow, Tetrahedron Lett., 1990, 31, 2957
5. 4. R. Rai and D. B. Collum, Tetrahedron Lett., 1994, 35, 6221
6. 5. J. Junggebauer and W. P. Neumann, Tetrahedron, 1997, 53, 1301 and references therein.
7. 6. (a) C. Chatgilialoglu, D. Griller and M. Lesage, J. Org. Chem., 1988, 53, 3641,
8. (b) K. J. Kulicke and B. Giese, Synlett, 1990, 91
9. 7. (a) D. H. R. Barton, D. O. Jang and J. Cs. Jaszberenyi, Tetrahedron Lett., 1992, 33, 5709
10. (b) D. O. Jang, Tetrahedron Lett., 1996, 1037
11. 8. C. Hackmann and H. J. Schäfer, Tetrahedron, 1993, 49, 4559
12. 9. R. McCague, R. G. Pritchard, R. J. Stoodley and D. S. Williamson, Chem. Commun., 1998, 2691.
13. 10. J. M. B. Calderon, G.J. Chicharro, R. J. Fiandorn, S. Huss and R. A. Ward, 97-EP2284 970506.