Antisense of c-fos gene attenuates Fos expression in the spinal cord induced by unilateral constriction of the sciatic nerve in the rat

Neuroscience Letters

Volumn 263, Issue 1, 1999, Pages 61-64

  Huang, Wen ^a   Simpson Jr , Richard K ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Antisense; C fos; Dorsal horn neurons; Sciatic nerve ligation; Spinal cord

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; PROTEIN C FOS;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE REPRESSION; INTRATHECAL DRUG ADMINISTRATION; MALE; NERVE INJURY; NONHUMAN; PAIN; PRIORITY JOURNAL; RAT; SCIATIC NERVE; SPINAL CORD DORSAL HORN;

ANIMALS; FUNCTIONAL LATERALITY; GENE EXPRESSION REGULATION; GENES, FOS; MALE; NEURONS; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, SPRAGUE-DAWLEY; SCIATIC NERVE; SPINAL CORD;

EID: 0033582964     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(99)00110-X     Document Type: Article

References (17)

1. Attal N., Jazat F., Kayser V., Guibaud G. Further evidence for 'pain-related' behaviors in a model of unilateral peripheral mononeuropathy. Pain. 41:1990;235-251.
2. Basbaum, A.I., Presley, R., Menetrey, D., Chi, S.I. and Levine, J.D. In F. Cervero, G.J. Bennett and P.M. Headley (Eds.), Processing of Sensory Information in the Superficial Dorsal Horn of the Spinal Cord, Plenum, New York, 1989, pp. 365-382.
3. Bennett G.J., Xie Y.-K. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. Pain. 33:1988;87-107.
4. Chiasson B.J., Armstrong J.N., Hooper M.L., Murphy P.R., Robertson H.A. The application of antisense oligonucleotide technology to the brain: some pitfalls. Cell. Mol. Neurobiol. 14:1994;507-521.
5. Chiu T.H., Dun S.L., Tang H., Dun N.J. c-fos antisense attenuateds Fos expression in rat central neurons induced by hemorrhage. NeuroReport. 5:1994;2178-2180.
6. Devor M., Claman D. Mapping and plasticity of acid phoaphatase afferents in the rat dorsal horn. Brain Res. 190:1980;17-28.
7. Dragunow M., Lawlor P., Chiasson B., Robertson H. c-fos antisense generates apomorphine and amphetamine-induced rotation. NeuroReport. 5:1993;305-306.
8. Gillardon F., Beck H., Uhlmann E., Herdegen T., Peyman A., Zimmermann M. Inhibition of c-Fos protein expression in rat spinal cord by antisense oligodeoxynecleotide superfusion. Eur. J. Neurosci. 66:1994;880-884.
9. Govrin-Lippmann R., Devor M. Ongoing activity in severed nerves: source and variation with time. Brain Res. 159(2):1978;406-410.
10. Heilig M., Engel J.A., Soderpalm B. C-fos antisense in the nucleus accumbens blocks the locomotor stimulation action of cocaine. Eur. J. Pharmacol. 263:1993;339-340.
11. Kajander K.C., Madsen A.M., Iadarola M.J., Draisci G., Wakisaka S. Fos-like immunoreactivity increases in the lumbar spinal cord following a chronic constriction injury to the sciatic nerve of rat. Neurosci. Lett. 206(1):1996;9-12.
12. Liu P.K., Salminen A., He Y., Jiang M.H., Xue J., Liu J.S., Hsu C.Y. Suppression of ischemia-induced Fos expression and AP-1 activity by an antisense oligodeoxynucleotide to c-fos mRNA. Ann. Neurol. 36:1994;566-576.
13. Morgan J.I., Cohen D.R., Hempsteal J.L., Currean T. Mapping patterns of c-fos expression in the central nervous system after seizure. Science. 237:1987;192-197.
14. Nishikura K., Murray H.M. Antisense RNA of protooncogene c-fos blocks renewed growth of quiescent 3T3 cells. Mol. Cell. Biol. 7:1987;637-649.
15. Simpson R.K. Jr., Huang W. glycine receptor reduction within segmental gray matter in a rat model of neuropathic pain. Neurol. Surg. 20:1998;161-168.
16. Swett J.E., Woolf C.J. The somatotopic organization of primary afferent terminals in the superficial laminae of the dorsal horn of the rat spinal cord. J. Comp. Neurol. 231:1985;66-77.
17. Uhlmann E., Peyman A. Antisense oligonucleotides: a new therapeutic principle. Chem. Rec. 90:1990;544-584.