Molecular cloning of human Fe65L2 and its interaction with the Alzheimer's β-amyloid precursor protein

Neuroscience Letters

Volumn 261, Issue 3, 1999, Pages 143-146

  Tanahashi, Hiroshi ^a   Tabira, Takeshi ^a  

^a NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

Author keywords

Alzheimer's disease; APP; APP like proteins; Fe65L2; PID PTB element; WW domain; Amyloid precursor protein

Indexed keywords

AMYLOID PRECURSOR PROTEIN; BINDING PROTEIN; PROTEIN FE65L2; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; DEMENTIA; HUMAN; HUMAN TISSUE; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; REVIEW;

EID: 0033582642     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(98)00995-1     Document Type: Article

References (18)

1. Blaikie P., Immanuel D., Wu J., Li N., Yajnik V., Margolis B. A region in Shc distinct from the SH2 domain can bind tyrosine-phosphorylated growth factor receptors. J. Biol. Chem. 269:1994;32031-32034.
2. Borg J.-P., Ooi J., Levy E., Margolis B. The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTN motif of amyloid precursor protein. Mol. Cell. Biol. 16:1996;6229-6241.
3. Borg J.-P., Yang Y., de Taddeo-Borg M., Margolis B., Turner R.S. The X11 alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion. J. Biol. Chem. 273:1998;14761-14766.
4. Chow N., Koremberg J.R., Chen X.-N., Neve R.L. APP-BP1, a novel protein that binds to the carboxyl-terminal region of the amyloid precursor protein. J. Biol. Chem. 271:1996;11339-11346.
5. Duilio A., Faffaella F., Minopoli G., Zambrano N., Russo T. Fe65L2: a new member of the Fe65 protein family interacting with the intracellula domain of the Alzheimer's beta-amyloid precursor protein. Biochem. J. 330:1998;513-519.
6. Fiore F., Zambrano N., Minopoli G., Donini V., Duilio A., Russo T. The regions of the Fe65 protein homologous to the phosphotyrosinc interaction/phosphotyrosine binding domain of Shc bind the intracellula domain of the Alzheimer's amyloid precursor protein. J. Biol. Chem. 270:1995;30853-30856.
7. Guenette S.Y., Chen J., Jondro P.D., Tanzi R.E. Association of a novel human FE65-like protein with the cytoplasmic domain of the beta amyloid precursor protein. Proc. Natl. Acad. Sci. USA. 93:1996;10832-10837.
8. Haass C., Selko D.J. Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide. Cell. 75:1993;1039-1040.
9. Hu Q., Kukull W.A., Bressler S.L., Gray M.D., Cam J.A., Larson E.B., Martin G.M., Deeb S.S. The human FE65 gene: genomic structure and an intronic biallelic polymorphism associated with sporadic dementia of the Alzheimer type. Hum. Genet. 103:1998;295-303.
10. Kang J., Lemaire H.G., Unterbeck A., Salbaum J.M., Masters C.L., Grzeschik K.H., Multhaup G., Beyreuther K., Muller-Hill B. The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature. 325:1987;733-736.
11. Lai A., Sisodia S.S., Trowbridge I.S. Characterization of sorting signals in the beta-amyloid precursor protein cytoplasmic domain. J. Biol Chem. 270:1995;3565-3573.
12. Nishimoto I., Okamoto T., Matsuura Y., Okamoto T., Murayama Y., Ogata E. Alzheimer amyloid protein precursor complexes with brain GTP-binding protein G(o). Nature. 362:1993;75-79.
13. Sastre M., Turner R.S., Levy E. X11 interaction with beta-amyloic precursor protein modulates its cellular stabilization and reduces amyloic beta-protein secretion. J. Biol. Chem. 273:1998;22351-22357.
14. Sudol M., Bork P., Einbond A., Kastury K., Druck T., Negrini M., Huebner K., Lehman D. Characterization of the mammalian YAP (Yes associated protein) gene and its role in defining a novel protein module, the WW domain. J. Biol. Chem. 270:1995;14733-14741.
15. Wasco W., Bupp K., Magendantz M., Gusella J., Tanzi R.E., Solomon F. Identification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid beta protein precursor. Proc. Natl. Acad. Sci. USA. 89:1992;10758-10762.
16. Wasco W., Gurubhagavatula S., Paradis M.D., Romano D.M., Sisodia S.S., Hyman B.T., Neve R.L., Tanzi R.E. Isolation and characterization of APLP2 encoding a homologue of the Alzheimer's associated amyloid beta protein precursor. Nat. Genet. 5:1993;95-100.
17. Zambrano N., Buxbaum J.D., Minopoli G., Fiore F., de Candia P., de Renzis S., Faraonio R., Sabo S., Cheetham J., Sudol M., Russo T. Interaction of the phosphotyrosine interaction/phosphotyrosine binding-related domains of Fe65 with wild-type and mutant Alzheimer's beta-amyloid precursor proteins. J. Biol. Chem. 272:1997;6399-6405.
18. Zambrano N., Minopoli G., de Candia P., Russo T. The Fe65 adaptor protein interacts through its PID1 domain with the transcription factor CP2/LSF/LBP1. J. Biol. Chem. 273:1998;20128-20133.