Structural dynamics in the guanylate cyclase heme pocket after CO photolysis

Journal of the American Chemical Society

Volumn 121, Issue 32, 1999, Pages 7397-7400

  Schelvis, Johannes P M ^a   Kim, Seonyoung ^c,d   Zhao, Yunde ^b   Marletta, Michael A ^b,c   Babcock, Gerald T ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

^d MiniMed Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON MONOXIDE; GUANYLATE CYCLASE; HEME; HISTIDINE; IRON; MUTANT PROTEIN; NITRIC OXIDE;

ALLOSTERISM; ARTICLE; CONFORMATIONAL TRANSITION; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME DEGRADATION; ENZYME MECHANISM; MOLECULAR DYNAMICS; PHOTOLYSIS; PROTEIN DOMAIN; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION;

EID: 0033581157     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja9909071     Document Type: Article

References (40)

1. 3, time-resolved RR; YC-1, 3-(5′-hydroxymethyl-2′-furyl)-1-benzyl indazole.
2. Waldman, S. A.; Murad, F. Pharmacol. Rev. 1987, 39, 163-196.
3. (b) Garbers, D. L.; Lowe, D. G. J. Biol. Chem. 1994, 269, 30741-30744.
4. Stone, J. R.; Marletta, M. A. Biochemistry 1994, 33, 5636-5640.
5. (b) Yu, A. E.; Hu, S.; Spiro, T. G.; Burstyn, J. N. J. Am. Chem. Soc. 1994, 116, 4117-4118.
6. (c) Stone, J. R.; Sands, R. H.; Dunham, W. R.; Marletta, M. A. Biochem. Biophys. Res. Comm. 1995, 207, 572-577.
7. (d) Deinum, G.; Stone, J. R.; Babcock, G. T.; Marletta, M. A. Biochemistry 1996, 35, 1540-1547.
8. (e) Dierks, E. A.; Hu, S.; Vogel, K. M.; Yu, A. E.; Spiro, T. G.; Burstyn, J. N. J. Am. Chem. Soc. 1997, 119, 7316-7323.
9. (f) Tomita, T.; Ogura, T.; Tsuyama, S.; Imai, Y.; Kitagawa, T. Biochemistry 1997, 36, 10155-10160.
10. Stone, J. R.; Marletta, M. A. Biochemistry 1995, 34, 14668-14674.
11. (b) Brandish, P.; Buechler, W.; Marletta, M. A. Biochemistry 1998, 37, 16898-16907.
12. Zhao, Y.; Marletta, M. A. Biochemistry 1997, 36, 15959-15964.
13. (b) Friebe, A.; Wedel, B.; Harteneck, C.; Foerster, J.; Koesling, D. Biochemistry 1997, 36, 1194-1198.
14. (c) Zhao, Y.; Hoganson, C. W.; Babcock, G. T.; Marletta, M. A. Biochemistry 1998, 37, 12458-12464.
15. Wedel, B.; Harteneck, C.; Foerster, J.; Friebe, A.; Schultz, G.; Koesling, D. J. Biol. Chem. 1995, 270, 24871-24875.
16. Verma, A.; Hirsch, D. J.; Glatt, C. E.; Ronnett, G. V.; Snyder, S. H. Science 1993, 259, 381-384.
17. (b) Zakhary, R.; Gaine, S. P.; Dinerman, J. L.; Ruat, M.; Flavahan, N. A.; Snyder, S. H. Proc. Natl. Acad. Sci. U.S.A. 1996, 93, 795-798.
18. Friebe, A.; Schultz, G.; Koesling, D. EMBO J. 1996, 15, 6863-6868.
19. (b) Friebe, A.; Koesling, D. Mol. Pharmacol. 1998, 53, 123-127.
20. (c) Stone, J. R.; Marletta, M. A. Chem. Biol. 1998, 5, 255-261.
21. (d) Hoenicka, M.; Becker, E. M.; Apeler, H.; Sirichoke, T.; Schroder, H.; Gerzer, R.; Stasch, J. P. J. Mol. Med. 1999, 77, 14-23.
22. Stone, J. R.; Marletta, M. A. Biochemistry 1995, 34, 16397-16403.
23. (b) Stone, J. R.; Marletta, M. A. Biochemistry 1996, 35, 1093-1099.
24. (c) Kharitonov, V. G.; Sharma, V. S.; Pilz, R. B.; Magde, D.; Koesling, D. Proc. Natl. Acad. Sci. U.S.A. 1995, 92, 2568-71.
25. (d) Kharitonov, V. G.; Sharma, V. S.; Magde, D.; Koesling, D. Biochemistry 1997, 36, 6814-6818.
26. (e) Sharma, V. S.; Magde, D.; Kharitonov, V. G.; Koesling, D. Biochem. Biophys. Res. Comm. 1999, 254, 188-191.
27. Rousseau, D. L.; Friedman, J. L. In Biological Applications of Raman Spectroscopy; Spiro, T. G., Ed.; John Wiley & Sons: New York, 1988; Vol. 3, pp 133-215.
28. (b) Nakashima, S.; Kitagawa, T. J. Am. Chem. Soc. 1994, 116, 10318-10319.
29. Findsen, E. W.; Centeno, J.; Babcock, G. T.; Ondrias, M. R. J. Am. Chem. Soc. 1987, 109, 5367-5372.
30. (b) Schelvis, J. P. M.; Deinum, G.; Varotsis, C. A.; Ferguson-Miller, S.; Babcock, G. T. J. Am. Chem. Soc. 1997, 119, 8409-8416.
31. Kim, S.; Marletta, M., manuscript in preparation.
32. Zhao, Y.; Schelvis, J. P. M.; Babcock, G. T.; Marletta, M. A. Biochemistry 1998, 37, 4502-4509.
33. Schelvis, J. P. M.; Zhao, Y.; Marletta, M. A.; Babcock, G. T. Biochemistry 1998, 37, 16289-16297.
34. Abe, M.; Kitagawa, T.; Kyogoku, Y. J. Chem. Phys. 1978, 69, 4526-4534.
35. (b) Choi, S.; Lee, J. J.; Wei, Y. H.; Spiro, T. G. J. Am. Chem. Soc. 1983, 105, 3692-3707.
36. Franzen, S.; Bohn, B.; Poyart, C.; DePillis, G.; Boxer, S. G.; Martin, J.-L. J. Biol. Chem 1995, 270, 1718-1720.
37. Stavrov, S. S. Biophys. J. 1993, 65, 1942-1950.
38. Teraoka, J.; Kitagawa, T. J. Biol. Chem. 1981, 256, 3969-3977.
39. Sun, J.; Loehr, T. M.; Wilks, A.; Ortiz de Montellano, P. In XVth International Conference on Raman Spectroscopy; Asher, S. A., Stein, P. B., Eds., Wiley: New York; 1996, pp 464-465.
40. YC-1 induces a conformational change in the heme pocket of sGC-CO (Denninger, J. R.; Schelvis, J. P. M.; Brandish, P. E.; Zhao, Y.; Babcock, G. T.; Marletta, M. A., unpublished results).