First total synthesis of tetrasubstituted tetrahydrofuran lignan, (-)- virgatusin

Tetrahedron Letters

Volumn 40, Issue 25, 1999, Pages 4701-4702

  Yoda, Hidemi ^a   Mizutani, Masato ^a   Takabe, Kunihiko ^a  

^a SHIZUOKA UNIVERSITY   (Japan)

Author keywords

( ) Virgatusin; Deoxygenation; Dihydroxyacetone; Furanolignan; Trisubstituted Lactone

Indexed keywords

TETRAHYDROFURAN DERIVATIVE; UNCLASSIFIED DRUG; VIRGATUSIN;

ARTICLE; DRUG CONFORMATION; DRUG ISOLATION; DRUG SYNTHESIS; PHYLLANTHUS; STEREOCHEMISTRY; STRUCTURE ANALYSIS;

PHYLLANTHUS VIRGATUS;

EID: 0033580952     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(99)00848-5     Document Type: Article

References (19)

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16. 9. The d.e. was determined by chiral HPLC using Daicel chiralpak AD after derivatization to the amide 6.
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19. 12. The absolute configuration of the generated stereogenic centre was determined unambiguously based on its spectral data of synthetic (-)-1.