Design and synthesis of cholestane derivatives bearing a cascade-type polyol and the effect of their property on a complement system in rat serum

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 2, 1999, Pages 205-208

  Nemoto, Hisao ^a   Kikuishi, Junya ^a   Yanagida, Shiho ^a   Kawano, Tomoaki ^a   Yamada, Mizuki ^a   Harashima, Hideyoshi ^a   Kiwada, Hiroshi ^a   Shibuya, Masayuki ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Cholesterol; Complement system; Liposome

Indexed keywords

CHOLESTANE DERIVATIVE; COMPLEMENT COMPONENT C3B; LIPOSOME; POLYOL;

ARTICLE; CHOLESTEROL TRANSPORT; COMPLEMENT SYSTEM; DERIVATIZATION; DRUG DESIGN; DRUG SYNTHESIS; ENCAPSULATION; MEMBRANE FILTER;

EID: 0033579975     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(98)00723-9     Document Type: Article

References (11)

1. H. Harashima, H. Matsuo and H. Kiwada, Advanced Drug Delivery Reviews, inpress.
2. B. P. Morgan. Complement, Academic Press Limited, London, 1990, pp. 1-35.
3. a) H. Harashima, T. M. Huong, T. Ishida, Y. Manabe, H. Matsuo and H. Kiwada, Pharm. Res. 1996, 13, 1702-1707.
4. b) H. Harashima, Y. Ochi and H. Kiwada, Biopharm. Drug Disposit. 1994, 15, 217-225.
5. a) H. Nemoto, J. G. Wilson, H. Nakamura, Y. Yamamoto, J. Org. Chem., 1992, 57, 435-435.
6. b) H. Nemoto, S. Iwamoto, H. Nakamura, Y. Yamamoto, Chem. Lett., 1994, 465-468.
7. c) H. Nemoto, J. Cai, Y. Yamamoto, J. Chem. Soc., Chem. Commun., 1994, 577-578.
8. d) H. Nemoto, J. Cai, N. Asao, S. Iwamoto, Y. Yamamoto, J. Med. Chem., 1995, 38, 1673-1678.
9. e) Y. Yamamoto, J. Cai, H. Nakamura, N. Sadayori, N. Asao, H. Nemoto, J. Org. Chem., 1995, 60, 3352-3357.
10. +).
11. K. Funato, R. Yoda, and H. Kiwada, Biochim. Biophys. Acta, 1992, 1103, 198-204.