The conserved arginine in Rho-GTPase-activating protein is essential for efficient catalysis but not for complex formation with Rho·GDP and aluminum fluoride

Biochemistry

Volumn 38, Issue 3, 1999, Pages 985-991

  Graham, Debbie L ^a,b   Eccleston, John F ^a   Lowe, Peter N ^b  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ALUMINUM FLUORIDE; ARGININE; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; LYSINE; RHO FACTOR;

ARTICLE; BINDING AFFINITY; CALORIMETRY; CATALYSIS; COMPLEX FORMATION; ENZYME ACTIVITY; NONHUMAN; PRIORITY JOURNAL;

ALANINE; ALUMINUM COMPOUNDS; ANTHRANILIC ACIDS; ARGININE; CATALYSIS; CONSERVED SEQUENCE; FLUORIDES; GTP PHOSPHOHYDROLASES; GTP-BINDING PROTEINS; GTPASE-ACTIVATING PROTEINS; GUANOSINE DIPHOSPHATE; GUANYLYL IMIDODIPHOSPHATE; HUMANS; LYSINE; MACROMOLECULAR SUBSTANCES; PROTEIN BINDING; RHO FACTOR;

EID: 0033579936     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9821770     Document Type: Article

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