Aberrant expression of MUC5AC and MUC6 gastric mucin genes in colorectal polyps

International Journal of Cancer

Volumn 80, Issue 2, 1999, Pages 210-218

  Bartman, Allen E ^a   Sanderson, Steven J ^a   Ewing, Stephen L ^b   Niehans, Gloria A ^b   Wiehr, Carol L ^a   Evans, Mary K ^a   Ho, Samuel B ^a,c  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MUCIN;

ANTIGEN EXPRESSION; ARTICLE; COLON POLYP; COLORECTAL CANCER; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STOMACH MUCOSA;

ADENOMATOUS POLYPOSIS COLI; CASE-CONTROL STUDIES; COLONIC POLYPS; COLORECTAL NEOPLASMS; GASTRIC MUCIN; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; HYPERPLASIA; IMMUNOHISTOCHEMISTRY; MUCINS;

EID: 0033579815     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19990118)80:2<210::AID-IJC9>3.0.CO;2-U     Document Type: Article

References (39)

1. BARA, J., ANDRÉ, J., GAUTIER, R. and BURTIN, P., Abnormal pattern of mucus-associated M1 antigens in histologically normal mucosa adjacent to colonic adenocarcinomas. Cancer Res., 44, 4040-4045 (1984).
2. BARA, J., CHASTRE, E., MAHIOU, J., SINGH, R.L., FORGUE-LAFITTE, M.E., HOLLANDE, E. and GODEAU, F., Gastric M1 mucin, an early oncofetal marker of colon carcinogenesis, is encoded by the MUC5AC gene. Int. J. Cancer, 75, 767-773 (1998).
3. BARA, J., GAUTIER, R., MOURADIAN, P., DECAENS, C. and DAHER, N., Oncofetal mucin M1 epitope family: characterization and expression during colon carcinogenesis. Int. J. Cancer, 47, 304-310 (1991).
4. BARA, J., LANGUILLE, O., GENDRON, M.C., DAHER, N., MARTIN, E. and BURTIN, P., Immunohistological study of precancerous mucus modification in human distal colonic polyps. Cancer Res., 43, 3885-3891 (1983).
5. BARA, J., LOISILLIER, F. and BURTIN, P., Antigens of gastric and intestinal mucous cells in human colonic tumors. Brit. J. Cancer, 41, 209-221 (1980).
6. BARBU, V. and DAUTRY, F., Northern blot normalization with a 28S rRNA oligonucleotide probe. Nucleic Acids Res., 17, 7115 (1989).
7. BARTMAN, A.E., BUISINE, M.-P., AUBERT, J.-P., NIEHANS, G.A., TORIBARA, N.W., KIM, Y.S., KELLEY, E.J., CRABTREE, J.E. and HO, S.B., The MUC6 secretory mucin gene is expressed in a wide variety of epithelial tissues. J. Pathol. (1998). (In press).
8. BOBEK, L.A., TSAI, H., BIESBROCK, A.R. and LEVINE, M.J., Molecular cloning, sequence, and specificity of expression of the gene encoding the low molecular weight human salivary mucin (MUC7). J. biol. Chem., 268, 20563-20569 (1993).
9. BOLAND, C.R. and DESHMUKH, G.D., The carbohydrate composition of mucin in colonic cancer. Gastroenterology, 98, 1170-1177 (1990).
10. BOLAND, C.R., MONTGOMERY, C.K. and KIM, Y.S., Alterations in human colonic mucin occurring with cellular differentiation and malignant transformation. Proc. nat. Acad. Sci. (Wash.), 79, 2051-2055 (1982).
11. BUISINE, M.-P., JANIN, A., MAUNOURY, V., AUDIE, J.-P., DELESCAUT, M.-P., COPIN, M.-C., COLOMBEL, J.-P., DEGAND, P., AUBERT, J.-P. and PORCHET, N., Aberrant expression of a human mucin gene (MUC5AC) in rectosigmoid villous adenoma. Gastroenterology, 110, 84-91 (1996).
12. CAMPBELL, B.J., FINNIE, I.A., HOUNSELL, E.F. and RHODES, J.M., Direct demonstration of increased expression of Thomsen-Friedenreich (TF) antigen in colonic adenocarcinoma and ulcerative colitis mucin and its concealment in normal mucin. J. clin. Invest., 95, 571-576 (1995).
13. CARRATO, C., BALAGUEé, C., DE BOLOS, C., GONZALEZ, E., GAMBUS, G., PLANAS, J., PERINI, J.M., ANDREU, D. and REAL, F.X., Differential apomucin expression in normal and neoplastic human gastrointestinal tissues. Gastroenterology, 107, 160-172 (1994).
14. CHOMCZYNSKI, P. and SACCHI, N., Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162, 156-159 (1987).
15. COLLINS, M.L. and HUNSAKER, W.R., Improved hybridization assays employing tailed oligonucleotide probes: a direct comparison with 5′-end-labeled oligonucleotide probes and nick-translated plasmid probes. Anal. Biochem., 151, 211-224 (1985).
16. DE BOLOS, C., GARRIDO, M. and REAL, F., MUC6 apomucin shows a distinct normal tissue distribution that correlates with Lewis antigen expression in the human stomach. Gastroenterology, 109, 723-734 (1995).
17. FEINBERG, A.P. and VOGELSTEIN, B., A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem., 132, 6-13 (1983).
18. GENDLER, S.J., LANCASTER, C.A., TAYLOR-PAPADIMITRIOU, J., DUHIG, T., PEAT, N., BURCHELL, J., PEMBERTON, L., LALANI, E.-N. and WILSON, D., Molecular cloning and expression of human tumor-associated polymorphic epithelial mucin. J. biol. Chem., 265, 15286-15293 (1990).
19. GIRLING, A., BARTKOVA, J., BURCHELL, J., GENDLER, S., GILLETT, C. and TAYLOR-PAPADIMITRIOU, J., A core protein epitope of the polymorphic epithelial mucin detected by the monoclonal antibody SM-3 is selectively exposed in a range of primary carcinomas. Int. J. Cancer, 43, 1072-1076 (1989).
20. GUM, J.R., BYRD, J.C., HICKS, J.W., TORIBARA, N.W., LAMPORT, D.T.A. and KIM, Y.S., Molecular cloning of human intestinal mucin cDNAs. Sequence analysis and evidence for genetic polymorphism. J. Biol. Chem., 264, 6480-6487 (1989).
21. GUM, J.R., HICKS, J.W., SWALLOW, D.M., LAGACE, R.L., BYRD, J.C., LAMPORT, D.T.A., SIDDIKI, B. and KIM, Y.S., Molecular cloning of cDNAs derived from a novel human intestinal mucin gene. Bioch. biophys. Res. Comm., 171, 407-415 (1990).
22. GUYONNET DUPERAT, V., AUDIE, J.-P., DEBAILLEUL, V., LAINE, A., BUISINE, M.-P., GALIÉGUE-ZOUITINA, S., PIGNY, P., DEGAND, P., AUBERT, J.-P. and PORCHET, N., Characterization of the human mucin gene MUC5AC: a consensus cysteine-rich domain for 11p15 mucin genes? Biochem. J., 305, 211-219 (1995).
23. HAKOMORI, S.I., Aberrant glycosylation in tumors and tumor-associated carbohydrate antigens. Adv. Cancer Res., 52, 257-331 (1989).
24. HIGGINS, P.J., FRIEDMAN, E., LIPKIN, M., HERTZ, R., ATTIYEH, F. and STONEHILL, E.H., Expression of gastric-associated antigens by human premalignant and malignant colonic epithelium. Oncology, 40, 26-30 (1983).
25. HO, S.B., EWING, S.L., MONTGOMERY, C.M. and KIM, Y.S., Altered mucin core peptide immunoreactivity in the colon polyp-carcinoma sequence. Oncol. Res., 8, 53-61 (1996).
26. HO, S.B. and KIM, Y.S., Carbohydrate antigens on cancer-associated mucin-like molecules. Semin. Cancer Biol., 2, 389-400 (1992).
27. HO, S.B., NIEHANS, G.A., LYFTOGT, C., YAN, P.-S., CHERWITZ, D.L., GUM, E.T., DAHIYA, R. and KIM, Y.S., Heterogeneity of mucin gene expression in normal and neoplastic tissues. Cancer Res., 53, 641-651 (1993).
28. HO, S.B., ROBERTON, A.M., SHEKELS, L.L., LYFTOGT, C.T., NIEHANS, G.A. and TORIBARA, N.W., Expression cloning of gastric mucin cDNA and localization of mucin gene expression. Gastroenterology, 109, 735-747 (1995a).
29. HO, S.B., SHEKELS, L.L., TORIBARA, N.W., KIM, Y.S., LYFTOGT, C., CHERWITZ, D.L. and NIEHANS, G.A., Mucin gene expression in normal, preneoplastic, and neoplastic human gastric epithelium. Cancer Res., 55, 2681-2690 (1995b).
30. KRIEG, P.A. and JOHNSON, A.D., In vitro synthesis of mRNA. In P.A. Krieg (ed.), A laboratory guide to RNA, pp. 141-154, Wiley-Liss, New York (1996).
31. LEE, J.J. and COSTLOW, N.A., A molecular titration assay to measure transcript prevalence levels. Meth. Enzymol., 152, 633-648 (1987).
32. MEERZAMAN, D., CHARLES, P., DASKAL, E., POLYMEROPOULOS, M.H., MARTIN, B.M. and ROSE, M.C., Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5). J. biol. Chem., 269, 12932-12939 (1994).
33. O'BRIEN, M.J., WINAWER, S.J., ZAUBER, A.G., GOTTLIEB, L.S., STERNBERG, S.S., DIAZ, B., DICKERSIN, G.R., EWING, S., GELLER, S., KASIMIAN, D., KOMOROWSKI, R. and SZPORN, A., The National Polyp Study. Patient and polyp characteristics associated with high-grade dysplasia in colorectal adenomas. Gastroenterology, 98, 371-379 (1990).
34. OGATA, S., UEHARA, H., CHEN, A. and ITZKOWITZ, S.H., Mucin gene expression in colonic tissues and cell lines. Cancer Res., 52, 5971-5978 (1992).
35. PORCHET, N., CONG, N.V., DUFOSSE, J., AUDIE, J.P., GUYONNET-DUPERAT, V., GROSS, M.S., DENIS, C., DEGAND, P., BERNHEIM, A. and AUBERT, J.P., Molecular cloning and chromosomal localization of a novel human tracheo-bronchial mucin cDNA containing tandemly repeated sequences of 48 base pairs. Biochem. biophys. Res. Comm., 175, 414-422 (1991).
36. SCHOEPPNER, H.L., RAZ, A., HO, S.B. and BRESALIER, R.S., Expression of an endogenous galactose-binding lectin correlates with neoplastic progression in the colon. Cancer, 75, 2818-2826 (1995).
37. SHEKELS, L.L., HUNNINGHAKE, D.A., TISDALE, A.S., GIPSON, I.K., KIELISZEWSJI, M., KOZAK, C.A. and HO, S.B., Cloning and characterization of mouse intestinal MUC3 mucin: 3′ sequence contains epidermal-growth-factor-like domains. Biochem. J., 330, 1301-1308 (1998).
38. TORIBARA, N.W., HO, S.B., GUM, E., GUM, J.R., LAU, P. and KIM, Y.S., The carboxyl-terminal sequence of the human secretory mucin, MUC6. Analysis of the primary amino acid sequence. J. biol. Chem., 272, 16398-16403 (1997).
39. TORIBARA, N.W., ROBERTON, A.M., HO, S.B., KUO, W.-L., GUM, E., HICKS, J.W., GUM, J.R., BYRD, J.C., SIDDIKI, B. and KIM, Y.S., Human gastric mucin: identification of a unique species by expression cloning. J. biol. Chem., 268, 5879-5885 (1993).