2,2-Dimethyl-2,3-dihydrofuran, a new substrate for intermolecular asymmetric Heck reactions

Tetrahedron Letters

Volumn 40, Issue 51, 1999, Pages 9163-9166

  Hennessy, Alan J ^a   Malone, Yvonne M ^a   Guiry, Patrick J ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

FURAN DERIVATIVE; LIGAND; PALLADIUM COMPLEX;

ARTICLE; CATALYSIS; CHEMICAL MODIFICATION; CHIRALITY; SYNTHESIS;

EID: 0033579621     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(99)01980-2     Document Type: Article

References (26)

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23. 2).
24. 2 at 80°C for 14 days giving a red solution with precipitation of base-HOTf. Pentane (10 ml) was then added to the reaction mixture and the resulting suspension was filtered through 2 cm of silica with further elution using diethyl ether (10 ml). This solution was concentrated and the yield calculated using GC. Further purification by preparative TLC gives 2,2-dimethyl-5-phenyl-2,5- dihydrofuran 9.
25. Racemic ,2-dimethyl-5-phenyl-2,5-dihydrofuran required for GC analysis was prepared from furan and iodobenzene using literature procedures: Larock, R. C.; Gong, W. H.; Baker, B. E. Tetrahedron Lett. 1989, 30, 2603.
26. Hennessy, A. J.; Connolly, D.; Guiry, P. J., unpublished results.