Regulation of myocardial glucose uptake and transport during ischemia and energetic stress

American Journal of Cardiology

Volumn 83, Issue 12 A, 1999, Pages 25-30

  Young, Lawrence H ^c   Russell III, Raymond R ^a   Yin, Renfu ^a   Caplan, Michael J ^a   Ren, Jianming ^b   Bergeron, Raynald ^a   Shulman, Gerald I ^a   Sinusas, Albert J ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BRISTOL MYERS SQUIBB   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE KINASE; ADENYLATE KINASE; GLUCOSE TRANSPORTER;

CONFERENCE PAPER; EXERCISE; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; GLUCOSE UTILIZATION; HEART HYPERTROPHY; HEART MUSCLE FIBER MEMBRANE; HEART MUSCLE ISCHEMIA; HEART MUSCLE METABOLISM; HEART STRESS; HEART VENTRICLE WORK; PRIORITY JOURNAL;

EID: 0033577959     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9149(99)00253-2     Document Type: Conference Paper

References (59)

1. Taegtmeyer H. Energy metabolism of the heart from basic concepts to clinical applications . Curr Prob Cardiol. 19:1994;57-116.
2. Barrett E., Schwartz R., Francis C., Zaret B. Regulation by insulin of myocardial glucose and fatty acid metabolism in the conscious dog. J Clin Invest. 74:1984;1073-1079.
3. Ferrannini E., Santoro D., Bonadonna R., Natali A., Parodi O., Camici P.G. Metabolic and hemodynamic effects of insulin on human hearts. Am J Physiol. 264:1993;E308-E315.
4. Gertz E.W., Wisneski J.A., Stanley W.C., Neese R.A. Myocardial substrate utilization during exercise in humans. Dual carbon-labeled carbohydrate isotope experiments. J Clin Invest. 82:1988;2017-2025.
5. Young L.H., Renfu Y., Russell R.R., Hu X., Caplan M.J., Ren J., Shulman G.I., Sinusas A.J. Low-flow ischemia leads to translocation of canine heart GLUT-4 and GLUT-1 glucose transporters to the sarcolemma in vivo. Circulation. 95:1997;415-422.
6. Maki M., Luotolahti M., Nuutila P., Iida H., Voipio-Pulkki L.M., Ruotsalainen U., Haaparanta M., Solin O., Hartiala J., Harkonen R., Knuuti J. Glucose uptake in the chronically dysfunctional but viable myocardium. Circulation. 93:1996;1658-1666.
7. 18F-2-deoxyglucose deposition and regional flow in pigs with chronically dysfunctional myocardium. Evidence for transmural variations in chronic hibernating myocardium. Circulation. 95:1997;1900-1909.
8. Yonekura Y., Brill A.B., Som P., Yamamoto K., Srivastava S.C., Iwai J., Elmaleh D.R., Livni E., Strauss H.W., Goodman M.M., Knapp F.F. Regional myocardial substrate uptake in hypertensive rats a quantitative autoradiographic measurement . Science. 227:1985;1494-1496.
9. Kagaya Y., Kanno Y., Takeyama D., Ishide N., Maruyama Y., Takahashi T., Ido T., Takishima T. Effects of long-term pressure overload on regional myocardial glucose and free fatty acid uptake in rats. A quantitative autoradiographic study. Circulation. 81:1990;1353-1361.
10. Allard M., Schonekess B., Henning S., English D., Lopaschuk G. Contribution of oxidative metabolism and glycolysis to ATP production in hypertrophied hearts. Am J Physiol. 267:1994;H742-H750.
11. Kashiwaya Y., Sato K., Tsuchiya N., Thomas S., Fell D.A., Veech R.L., Passonneau J.V. Control of glucose utilization in working perfused rat heart. J Biol Chem. 269:1994;25502-25514.
12. Ren J., Marshall B., Gulve E., Gao J., Johnson D., Holloszy J., Mueckler M. Evidence from transgenic mice that glucose transport is rate-limiting for glycogen deposition and glycolysis in skeletal muscle. J Biol Chem. 268:1993;16113-16115.
13. Mueckler M. Facilitative glucose transporters. Eur J Biochem. 219:1994;713-725.
14. Stephens J., Pilch P. The metabolic regulation and vesicular transport of GLUT4, the major insulin-responsive glucose transporter. Endocr Rev. 16:1995;529-546.
15. Slot J.W., Geuze H.J., Gigengack S., James D.E., Lienhard G.E. Translocation of the glucose transporter GLUT4 in cardiac myocytes of the rat. Proc Natl Acad Sci USA. 88:1991;7815-7819.
16. Sun D., Nguyen N., DeGrado T.R., Schwaiger M., Brosius F.C. Ischemia induces translocation of the insulin-responsive glucose transporter GLUT4 to the plasma membrane of cardiac myocytes. Circulation. 89:1994;793-798.
17. Fischer Y., Thomas J., Sevilla L., Muñoz P., Becker C., Holman G., Kozka I., Palacín M., Testar X., Kammermeier H., Zorzano A. Insulin-induced recruitment of glucose transporter 4 (GLUT4) and GLUT1 in isolated rat cardiac myocytes. J Biol Chem. 272:1997;7085-7092.
18. Russell R.R., Yin R., Caplan M.J., Hu X., Ren J., Shulman G.I., Sinusas A.J., Young L.H. Additive effects of hyperinsulinemia and ischemia on myocardial GLUT1 and GLUT4 translocation in vivo. Circulation. 98:1998;2180-2186.
19. Cartee G.D., Douen A.G., Ramlal T., Klip A., Holloszy J.O. Glucose transport in skeletal muscle stimulation by hypoxia . J Appl Physiol. 70:1991;1593-1600.
20. Zierath J.R., Tsao T.S., Stenbit A.E., Ryder J.W., Galuska D., Charron M.J. Restoration of hypoxia-stimulated glucose uptake in GLUT4-deficient muscles by muscle-specific GLUT4 transgenic complementation. J Biol Chem. 273:1998;20910-20915.
21. Douen A., Ramlal T., Rastogi S., Bilan P., Cartee G., Vranic M., Holloszy J., Klip A. Exercise induces recruitment of the "insulin-responsive glucose transporter." J Biol Chem. 265:1990;13427-13430.
22. Gao J., Ren J., Gulve E.A., Holloszy J.O. Additive effect of contractions and insulin on GLUT-4 translocation into the sarcolemma. J Appl Physiol. 77:1994;1597-1601.
23. Lund S., Holman G., Schmitz O., Pedersen O. Contraction stimulates translocation of glucose transporter GLUT4 in skeletal muscle through a mechanism distinct from that of insulin. Proc Natl Acad Sci USA. 92:1995;5817-5821.
24. Mueckler M., Hresko R.C., Sato M. Structure, function and biosynthesis of GLUT1. Biochem Soc Trans. 25:1997;951-954.
25. Kraegen E.W., Sowden J.A., Halstead M.B., Clark P.W., Rodnick K.J., Chisholm D.J., James D.E. Glucose transporters and in vivo glucose uptake in skeletal and cardiac muscle fasting, insulin stimulation and immunoisolation studies of GLUT1 and GLUT4 . Biochem J. 295:1993;287-293.
26. Doria-Medina C.L., Lund D.D., Pasley A., Sandra A., Sivitz W.I. Immunolocalization of GLUT-1 glucose transporter in rat skeletal muscle and in normal and hypoxic cardiac tissue. Am J Physiol. 265:1993;E454-E466.
27. Handberg A., Kayser L., Hoyer P., Vinten J. A substantial part of GLUT-1 in crude membranes from muscle originates from perineurial sheaths. Am J Physiol. 262:1992;E721-E727.
28. Carlsten A., Hallgren B., Jagenburg R., Werko L. Myocardial metabolism of glucose, lactic acid, amino and fatty acids in healthy individuals at rest and at different work loads. Scan J Clin Invest. 13:1961;418-427.
29. Camici P., Marraccini P., Marzilli M., Lorenzoni R., Buzzigoli G., Puntoni R., Boni C., Bellina C.R., Klassen G.A., L'Abbate A., et al. Coronary hemodynamics and myocardial metabolism during and after pacing stress in normal humans. Am J Physiol. 257:1989;E309-E317.
30. Neely J., Bowman R., Morgan H. Effects of ventricular pressure development and palmitate on glucose transport. Am J Physiol. 216:1969;804-811.
31. Taegtmeyer H., Hems R., Krebs H. Utilization of energy providing substrates in the isolated working rat heart. Biochem J. 186:1980;701-711.
32. Zaninetti D., Greco-Perotto R., Jeanrenaud B. Heart glucose transport and transporters in rat heart regulation by insulin, workload and glucose . Diabetologia. 31:1988;108-113.
33. Wheeler T.J., Fell R.D., Hauck M.A. Translocation of two glucose transporters in heart effects of rotenone, uncouplers, workload, palmitate, insulin and anoxia . Biochim Biophys Acta. 1196:1994;191-200.
34. Kolter T., Uphues I., Wichelhaus A., Reinauer H., Eckel J. Contraction-induced translocation of the glucose transporter Glut4 in isolated ventricular cardiomyocytes. Biochem Biophys Res Commun. 189:1992;1207-1214.
35. Nuutila P., Maki M., Laine H., Knuuti M.J., Ruotsalainen U., Luotolahti M., Haaparanta M., Solin O., Jula A., Koivisto V.A., et al. Insulin action on heart and skeletal muscle glucose uptake in essential hypertension. J Clin Invest. 96:1995;1003-1009.
36. Grover-McKay M., Schwaiger M., Krivokapich J., Perloff J.K., Phelps M.E., Schelbert H.R. Regional myocardial blood flow and metabolism at rest in mildly symptomatic patients with hypertrophic cardiomyopathy. J Am Coll Cardiol. 13:1989;317-324.
37. Morgan H., Henderson M., Regen D., Park C. Regulation of glucose uptake in muscle. I. Effects of insulin and anoxia on glucose transport and phosphorylation in the isolated perfused heart of normal rats. J Biol Chem. 236:1961;253-261.
38. Wheeler T.J. Translocation of glucose transporters in response to anoxia in heart. J Biol Chem. 263:1988;19447-19454.
39. Bashan N., Burdett E., Guma A., Sargeant R., Tumiati L., Liu Z., Klip A. Mechanisms of adaptation of glucose transporters to changes in the oxidative chain of muscle and fat cells. Am J Physiol. 264:1993;C430-C440.
40. Stanley W.C., Hall J.L., Stone C.K., Hacker T.A. Acute myocardial ischemia causes a transmural gradient in glucose extraction but not in glucose uptake. Am J Physiol. 262:1992;H91-H96.
41. Hall J., Hernandez L., Henderson J., Kellerman L., Stanley W. Decreased interstitial glucose and transmural gradient in lactate during ischemia. Basic Res Cardiol. 89:1994;468-486.
42. Rovetto M.J., Lamberton W.F., Neely J.R. Mechanisms of glycolytic inhibition in ischemic rat hearts. Circ Res. 37:1975;742-750.
43. Lee A., Hansen P., Holloszy J. Wortmannin inhibits insulin-stimulated but not contraction-stimulated glucose transport activity in skeletal muscle. FEBS Lett. 361:1995;51-54.
44. Hayashi T., Wojtaszewski J.F., Goodyear L.J. Exercise regulation of glucose transport in skeletal muscle [Review]. Am J Physiol. 273:1997;E1039-E1051.
45. Hardie D., Carling D. The AMP-activated protein kinase fuel gauge of the mammalian cell? Eur J Biochem. 246:1997;259-273.
46. Winder W.W., Hardie D.G. Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise. Am J Physiol. 270:1996;EE299-EE304.
47. Kudo N., Barr A.J., Barr R.L., Desai S., Lopaschuk G.D. High rates of fatty acid oxidation during reperfusion of ischemic hearts are associated with a decrease in malonyl-CoA levels due to an increase in 5′-AMP-activated protein kinase inhibition of acetyl-CoA carboxylase. J Biol Chem. 270:1995;17513-17520.
48. Davies S., Carling D., Hardie D. Tissue distribution of the AMP-activated protein kinase, and lack of activation by cyclic-AMP-dependent protein kinase, studied using a specific and sensitive peptide assay. Eur J Biochem. 186:1989;123-128.
49. Ponticos M., Lu Q.L., Morgan J.E., Hardie D.G., Partridge T.A., Carling D. Dual regulation of the AMP-activated protein kinase provides a novel mechanism for the control of creatine kinase in skeletal muscle. EMBO J. 17:1998;1688-1699.
50. Hardie D.G., Carling D. The AMP-activated protein kinase-fuel gauge of the mammalian cell? Eur J Biochem. 246:1997;259-273. [Review].
51. Henin N., Vincent M., Van den Berghe G. Stimulation of rat liver AMP-activated protein kinase by AMP analogues. Biochim Biophys Acta. 1290:1996;197-203.
52. Hutber C.A., Hardie D.G., Winder W.W. Electrical stimulation inactivates muscle acetyl-CoA carboxylase and increases AMP-activated protein kinase. Am J Physiol. 272:1997;E262-E266.
53. Reibel D., Rovetto M. Myocardial ATP synthesis and mechanical function following oxygen deficiency. Am J Physiol. 234:1978;H620-H624.
54. Neely J., Denton R., England P., Randle P. The effects of increased heart work on the tricarboxylate cycle and its interactions with glycolysis in the perfused rat heart. Biochem J. 128:1972;147-159.
55. Corton J.M., Gillespie J.G., Hawley S.A., Hardie D.G. 5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells? Eur J Biochem. 229:1995;558-565.
56. Merrill G.F., Kurth E.J., Hardie D.G., Winder W.W. AICA riboside increases AMP-activated protein kinase, fatty acid oxidation, and glucose uptake in rat muscle. Am J Physiol. 273:1997;E1107-E1112.
57. Russell RR, Bergeron R, Shulman GI, Young LH. Translocation of myocardial GLUT4 and increased glucose uptake through activation of AMP-activated protein kinase by AICAR. Am J Physiol (in press).
58. Hayashi T., Hirshman M.F., Kurth E.J., Winder W.W., Goodyear L.J. Evidence for 5′ AMP-activated protein kinase mediation of the effect of muscle contraction on glucose transport. Diabetes. 47:1998;1369-1373.
59. Bergeron R., Russell R.R., Young L.H., Ren J.M., Marcucci M., Lee A., Shulman G.I. Effect of AMPK activation on muscle glucose metabolism in conscious rats. Am J Physiol. 276:1999;E938-E944.