Enhancing solid phase synthesis by a noncovalent protection strategy - Efficient coupling of rhodamine to resin-bound peptide nucleic acids

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 10, 1999, Pages 1419-1422

  Mayfield, Lynn D ^a   Corey, David R ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORESCENT DYE; MACROGOL; OLIGOMER; PEPTIDE NUCLEIC ACID; POLYSTYRENE; RESIN; RHODAMINE;

ABSORPTION; ARTICLE; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROPHOBICITY; PEPTIDE SYNTHESIS; SOLID STATE;

BASE SEQUENCE; PEPTIDE NUCLEIC ACIDS; RHODAMINES;

EID: 0033577765     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00200-0     Document Type: Article

References (6)

1. Meldal, M. Meth. Enzymol. 1997, 289, 83
2. Han, Y.; Botems, S. L.; Hegyes, P.; Munson, M. C.; Minor, C. A.; Kates, S. A.; Albericio, F.; Barany, G. J. Org. Chem. 1996, 61, 6326.
3. Egholm, M.; Buchardt, O.; Christensen, L.; Behrens, C.; Freier, S. M.; Driver, D. A.; Berg., R. H.; Kim, S. K.; Nordern, B.; Neilsen, P. E. Nature 1993, 365, 566.
4. Mayfield, L. D.; Corey, D. R. Analytical Biochem. 1999, in Press.
5. Landsdorp, P. M.; Verwoerd, N. P.; van de Rijke, F. M.; Dragowska, V.; Little, M-T.; Dirks, R. W.; Raap, A. K.; Tanke, H. J. Hum. Mol. Gen. 1996, 5, 685.
6. Hamilton, S. E.; Simmons, C. G.; Kathiriya, I.; Corey, D. R. Chemistry and Biology 1999, in press.