Influence of denervation on neurogenic inhibitory response of corpus cavernosum and nitric oxide synthase histochemistry

Brain Research

Volumn 825, Issue 1-2, 1999, Pages 14-21

  Ayajiki, Kazuhide ^a   Hayashida, Hideshi ^a   Okamura, Tomio ^a   Toda, Noboru ^a  

^a SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

Author keywords

Corpus cavernosum; Denervation; Histochemistry; Nitric oxide (NO) synthase; Nitroxidergic nerve

Indexed keywords

ARGININE; ENDOTHELIN 1; N(G) NITROARGININE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; PRAZOSIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS CAVERNOSUM; DENERVATION; DOG; ELECTROSTIMULATION; GANGLION; HISTOCHEMISTRY; MALE; NERVE CELL; NERVE ENDING; NERVE FIBER; NERVE PLEXUS; NONHUMAN; PELVIC NERVE; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATE; ANIMALS; DENERVATION; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; MALE; NADPH DEHYDROGENASE; NERVE FIBERS; NEURAL INHIBITION; NICOTINE; NICOTINIC AGONISTS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITROARGININE; PENIS; PRAZOSIN; STIMULATION, CHEMICAL; SYMPATHOLYTICS; TETRODOTOXIN;

EID: 0033577510     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(99)01204-4     Document Type: Article

References (20)

1. K.-E. Andersson, G. Wagner, Physiology of penile erection, Physiol. Rev. 75 (1995) 191-236.
2. K. Ayajiki, H. Hayashida, T. Okamura, N. Toda, Pelvic nerve stimulation-induced pressor responses in corpus cavernosum of anesthetized dogs, Am. J. Physiol. 273 (1997) H2141-H2145.
3. A.L. Burnett, C.J. Lowenstein, D.S. Bredt, T.S.K. Chang, S.H. Snyder, Nitric oxide: a physiologic mediator of penile erection, Science 257 (1992) 401-403.
4. A.L. Burnett, S.L. Tillman, T.S.K. Chang, J.I. Epstein, C.J. Lowenstein, D.S. Bredt, S.H. Snyder, P.C. Walsh, Immunohistochemical localization of nitric oxide synthase in the autonomie innervation of the human penis, J. Urol. 150 (1993) 73-76.
5. W.G. Dail, R.W. Harmill, Parasympathetic nerves in penile erectile tissue of the rat contain choline acetyltransferase, Brain Res. 487 (1989) 165-170.
6. T.M. Dawson, D.S. Bredt, M. Fotuhi, P.M. Hwang, S.H. Snyder, Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues, Proc. Natl. Acad. Sci. USA 88 (1991) 7797-7801.
7. R.F. Furchgott, Studies on relaxation of rabbit aorta by sodium nitrite: the basis for the proposal that the acid-activatable inhibitory factor from bovine retractor penis is inorganic nitrite and the endothelium-derived relaxing factor is nitric oxide, in: P.M. Vanhoutte (Ed.), Vasodilatation, Vol. IV, Raven, New York, 1988, pp. 401-414.
8. H. Hayashida, T. Okamura, T. Tomoyoshi, N. Toda, Neurogenic nitric oxide mediates relaxation of canine corpus cavernosum, J. Urol. 155 (1996) 1122-1127.
9. G-nitro-L-arginine on the erectile response to cavernous nerve stimulation in the rabbit, Acta Physiol. Scand. 143 (1991) 299-304.
10. L.J. Ignarro, P.A. Bush, G.M. Buga, K.S. Wood, J.M. Fukuto, J. Rajfer, Nitric oxide and cyclic GMP formation upon electrical field stimulation cause relaxation of corpus cavernosum smooth muscle, Biochem. Biophys. Res. Commun. 170 (1990) 843-850.
11. S. Moncada, R.M.J. Palmer, E.A. Higgs, Nitric oxide: physiology, pathophysiology, and pharmacology, Pharmacol. Rev. 43 (1991) 109-142.
12. R.S. Pickard, P.H. Powell, M.A. Zar, Evidence against vasoactive intestinal polypeptide as the relaxant neurotransmitter in human cavernosal smooth muscle, Br. J. Pharmacol. 108 (1993) 497-500.
13. Y. Tanobe, T. Okamura, M. Fujimura, N. Toda, Functional role and histological demonstration of nitric oxide-mediated inhibitory nerves in dog sphincter of Oddi, Neurogastroenterol. Motil. 7 (1995) 219-227.
14. N. Toda, Nicotine-induced relaxation in isolated canine cerebral arteries, J. Pharmacol. Exp. Ther. 193 (1975) 376-384.
15. + and nicotine in dog duodenal longitudinal muscle, J. Pharmacol. Exp. Ther. 260 (1992) 697-701.
16. N. Toda, T. Okamura, Nitroxidergic nerve: regulation of vascular tone and blood flow in the brain, J. Hypertension 14 (1996) 423-436.
17. N. Toda, M. Uchiyama, T. Okamura, Prejunctional modulation of nitroxidergic nerve function in canine cerebral arteries, Brain Res. 700 (1995) 213-218.
18. F. Trigo-Rocha, W.J. Aronson, M. Hohenfellner, L.J. Ignarro, J. Rajfer, T.F. Lue, Nitric oxide and cGMP: mediators of pelvic nerve-stimulated erection in dogs, Am. J. Physiol. 264 (1993) H419-H422.
19. S.R. Vincent, Nitric Oxide in the Nervous System, Academic Press, New York, 1995.
20. Y. Yoshida, K. Yoshida, T. Kimura, N. Toda, Distribution of NADPH diaphorase-reactive nerves in the human female genital organ, Acta Obstet. Gynecol. Scand. 74 (1995) 171-176.