Coevolutionary analysis of resistance-evading peptidomimetic inhibitors of HIV-1 protease

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 4, 1999, Pages 1369-1374

  Rosin, Christopher D ^a,b   Belew, Richard K ^a   Morris, Garrett M ^b   Olson, Arthur J ^b   Goodsell, David S ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINASE; PROTEINASE INHIBITOR;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; DRUG DESIGN; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME SPECIFICITY; MUTATION; PRIORITY JOURNAL; VIRUS RESISTANCE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; DRUG DESIGN; EVOLUTION, MOLECULAR; HIV PROTEASE; HIV PROTEASE INHIBITORS; HIV-1; KINETICS; POINT MUTATION; THERMODYNAMICS;

HUMAN IMMUNODEFICIENCY VIRUS 1; RNA VIRUSES;

EID: 0033573903     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.4.1369     Document Type: Article

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