USP25, a novel gene encoding a deubiquitinating enzyme, is located in the gene-poor region 21q11.2

Genomics

Volumn 62, Issue 3, 1999, Pages 395-405

  Valero, Rebeca ^a   Marfany, Gemma ^a   González Angulo, Olga ^a   González González, Gertrudis ^b   Puelles, Luis ^b   Gonzàlez Duarte, Roser ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b UNIVERSITY OF MURCIA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; BIRTH DEFECT; CHROMOSOME 21Q; DOWN SYNDROME; FETUS; GENE MAPPING; GENOME; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; TRISOMY 21;

ANIMALIA; MURINAE;

EID: 0033572623     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1999.6025     Document Type: Article

References (45)

1. Altschul, S. F., Madden, T. L., Schaffer, A. A., Zhang, J., Zhang, Z., Miller, W., and Lipman, D. J. (1997). Gapped BLAST and PSI-BLAST: A new generation of protein database search programs. Nucleic Acids Res. 25: 3389-3402.
2. Bird, A. (1986). CpG-rich islands and the function of DNA methylation. Nature 32: 209-213.
3. Burset, M., and Guigó, R. (1996). Evaluation of gene structure prediction programs. Genomics 34: 357-367.
4. Chumakov, I., Rigault, P., Guillou, S., Ougen, P., Billaut, A., Guasconi, G., Gervy, P., LeGall, I., Soularue, P., and Grinas, L. (1992). Continuum of overlapping clones spanning the entire human chromosome 21q. Nature 359: 380-387.
5. Cross, S. H., and Bird, A. P. (1995). CpG islands and genes. Curr. Opin. Genet. Dev. 5: 309-314.
6. D'Andrea, A., and Pellman, D. (1998). Deubiquitinating enzymes: A new class of biological regulators. Crit. Rev. Biochem. Mol. Biol. 33: 337-352.
7. De Sario, A., Roizes, G., Allegre, N., and Bernardi, G. (1997). A compositional map of the cen-q21 region of human chromosome 21. Gene 194: 107-113.
8. Delabar, J. M., Theophile, D., Rahmani, Z., Chettouh, Z., Blouin, J. L., Prieur, M., Noel, B., and Sinet, P. M. (1993). Molecular mapping of twenty-four features of Down syndrome on chromosome 21. Eur. J. Hum. Genet. 1: 114-124.
9. Delabar, J., Antonarakis, S. E., Brahe, C., Estivill, X., Pritchard, M., Fisher, E., Kessling, A., Yaspo, M. L., Nizetic, D., Bricarelli, D., Oliva, R., Petersen, M. B., Potier, M. C., Roizes, G., Van Broeckhoven, C., Sverdlov, E., and Yurov, Y. (1998). Construction of a high resolution map of chromosome 21 integrating genetic, physical, overlap and transcriptional data. Hum. Genome Anal. 23: 150-174.
10. Depiereux, E., Baudoux, G., Briffeuil, P., Reginster, I., De Bolle, X., Vinals, C., and Feytmans, E. (1997). Match-Box server: A multiple sequence alignment tool placing emphasis on reliability. CABIOS 13: 249-256.
11. Dynan, W. S., and Tjian, R. (1985). Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins. Nature 316: 774-778.
12. Frederick, A., Rolfe, M., and Chiu, M. I. (1998). The human UNP locus at 3p21.31 encodes two tissue-selective, cytoplasmic isoforms with deubiquitinating activity that have reduced expression in small cell lung carcinoma cell lines. Oncogene 16: 153-165.
13. Gardiner, K. (1996). Base composition and gene distribution: Critical patterns in mammalian genome organization. Trends Genet. 12: 519-524.
14. Gardiner, K., Aissani, B., and Bernardi, G. (1990a). A compositional map of human chromosome 21. EMBO J. 9: 1853-1858.
15. Gardiner, K., Horisberger, M., Kraus, J., Tantravahi, U., Korenberg, J., Rao, V., Reddy, S., and Patterson, D. (1990b). Analysis of human chromosome 21: Correlation of physical and cytogenetic maps: Gene and CpG island distributions. EMBO J. 9: 25-34.
16. Gardiner-Garden, M., and Frommer, M. (1987). CpG islands in vertebrate genomes. J. Mol. Biol. 196: 261-282.
17. Groet, J., Ives, J. H., South, A. P., Baptista, P. R., Jones, T. A., Yaspo, M. L., Lehrach, H., Potier, M. C., Van Broeckhoven, C., and Nizetic, D. (1998). Bacterial contig map of the 21q11 region associated with Alzheimer's disease and abnormal myelopoiesis in Down syndrome. Genome Res. 8: 385-398.
18. Hansen-Hagge, T. E., Janssen, J. W. G., Hameister, H., Papa, F. R., Zechner, U., Seriu, T., Jauch, A., Becke, D., Hochstrasser, M., and Bartram, C. R. (1998). An evolutionarily conserved gene on human chromosome 5q33-q34, UBH1, encodes a novel deubiquitinating enzyme. Genomics 49: 411-418.
19. Henrique, D., Adam, J., Myat, A., Chitnis, A., Lewis, J., and Ish-Horowicz, D. (1995). Expression of a Delta homologue in prospective neurons in the chick. Nature 375: 787-790.
20. Hershko, A., and Ciechanover, A. (1998). The ubiquitin system. Annu. Rev. Biochem. 67: 425-479.
21. Hochstrasser, M. (1995). Ubiquitin, proteasomes, and the regulation of intracellular protein degradation. Curr. Opin. Cell Biol. 7: 215-223.
22. Hochstrasser, M. (1996). Ubiquitin-dependent protein degradation. Annu. Rev. Genet. 30: 405-439.
23. Jones, M. H., Furlong, R. A., Burkin, H., Chalmers, I. J., Brown, G. M., Khwaja, O., and Affara, N. A. (1996). The Drosophila developmental gene fat facets has a human homologue in Xp11.4 which escapes X-inactivation and has related sequences on Yq11.2. Hum. Mol. Genet. 5: 1695-1701.
24. Kajimoto, Y., Hashimoto, T., Shirai, Y., Nishino, N., Kuno, T., and Tanaka, C. (1992). cDNA cloning and tissue distribution of rat ubiquitin carboxyl-terminal hydrolase PGP9.5. J. Biochem. 112: 28-32.
25. Kao, F. T., Yu, J., Tong, S., Qi, J., Patanjali, S. R., Weissman, S. M., and Patterson, D. (1994). Isolation and refined regional mapping of expressed sequences from human chromosome 21. Genomics 23: 700-703.
26. Korenberg, J. R., Chen, X. N., Schipper, R., Sun, Z., Gonsky, R., Gerwehr, S., Carpenter, N., Daumer, C., Dignan, P., and Disteche, C. (1994). Down syndrome phenotypes: The consequences of chromosomal imbalance. Proc. Natl. Acad. Sci. USA 91: 4997-5001.
27. Kozak, M. (1996). Interpreting cDNA sequences: Some insights from studies on translation. Mamm. Genome 7: 563-574.
28. Kurnit, D. M., Cheng, J.-F., Zhu, Y., Van Keuren, M. L., Jiang, Y., Pan, Y.-Z., Whitley, K., and Crombez, E. (1995). Transcription patterns of sequences on human chromosome 21. Cytogenet. Cell Genet. 71: 203-206.
29. Liu, L. Q., Robert Ilaria, J. R., Kingsley, P. D., Iwama, A., Van Etten, R. A., Palis, J., and Zhang, D. E. (1999). A novel ubiquitin-specific protease, UBP43, cloned from leukemia fusion protein AML1-ETO-expressing mice, functions in hematopoietic cell differentiation. Mol. Cell. Biol. 19: 3029-3038.
30. Lovett, M., Kere, J., and Hinton, L. M. (1991). Direct selection: A method for the isolation of cDNA encoded by large genomic regions. Proc. Natl. Acad. Sci. USA 88: 9628-9632.
31. Lowe, J., Mcdermott, H., Landon, M., Mayer, R. J., and Wilkinson, K. D. (1990). Ubiquitin carboxyl-terminal hydrolase (PGP9.5) is selectively present in ubiquitinated inclusion bodies characteristic of human neurodegenerative diseases. J. Pathol. 161: 153-160.
32. Niikawa, N., Deng, X.-H., Abe, K., Harada, N., Okada, T., Tsuchiya, I., Akaboshi, I., Matsuda, I., Fukushima, Y., Kaneko, Y., Kuwano, A., and Kajii, T. (1991). Possible mapping of the gene for transient myeloproliferative syndrome at 21q11.2. Hum. Genet. 87: 561-566.
33. Nizetic, D., Gellen, L., Hamvas, R. M., Mott, R., Grigoriev, A., Vatcheva, R., Zehetner, G., Yaspo, M. L., Dutriaux, A., Lopes, C., et al. (1994). An integrated YAC-overlap and 'cosmid-pocket' map of the human chromosome 21. Hum. Mol. Genet. 3: 759-770.
34. Papa, F. R., and Hochstrasser, M. (1993). The yeast DOA4 gene encodes a deubiquitinating enzyme related to a product of the human tre-2 oncogene. Nature 366: 313-319.
35. Potier, M., Dutriaux, A., Orti, R., Groet, J., Gibelin, N., Karadima, G., Lutfalla, G., Lynn, A., Van Broeckhoven, C., Chakravarti, A., Petersen, M., Nizetic, D., Delabar, J., and Rossier, J. (1998). Two sequence-ready contigs spanning the two copies of a 200-kb duplication on human 21q: Partial sequence and polymorphisms. Genomics 51: 417-426.
36. Rahmani, Z., Blouin, J. L., N., C.-G., Watkins, P. C., Mattei, J. F., Poissonnier, M., Prieur, M., Chettouh, Z., Nicole, A., and Aurias, A. (1989). Critical role of the D21S55 region on chromosome 21 in the pathogenesis of Down syndrome. Proc. Natl. Acad. Sci. USA 86: 5958-5962.
37. Saigoh, K., Wang, Y.-L., Suh, J.-G., Yamanishi, T., Sakai, Y., Kiyosawa, H., Harada, T., Ichihara, N., Wakana, S., Kikuchi, T., and Wada, K. (1999). Intragenic deletion in the gene encoding ubiquitin carboxy-terminal hydrolase in gad mice. Nat. Genet. 23: 47-51.
38. Schofield, J. N., Day, I. N. M., Thompson, R. J., and Edwards, Y. H. (1995). PGP9.5, a ubiquitin C-terminal hydrolase: Pattern of mRNA and protein expression during neural development in the mouse. Dev. Brain Res. 85: 229-238.
39. Schug, J., and Overton, G. (1997). Modeling transcription factor binding sites with Gibbs sampling and Minimum Description Length encoding. ISMB 5: 268-271.
40. Tassone, F., Xu, H., Burkin, H., Weissman, S., and Gardiner, K. (1995). cDNA selection from 10 Mb of chromosome 21 DNA: Efficiency in transcriptional mapping and reflections of genome organization. Hum. Mol. Genet. 4: 1509-1518.
41. Van Broeckhoven, C. (1995). Molecular genetics of Alzheimer disease: Identification of genes and gene mutations. Eur. Neurol. 35: 8-19.
42. Wilkinson, D. G., and Nieto, M. A. (1993). Detection of messenger RNA by in situ hybridization to tissue sections and whole mounts. Methods Enzymol. 225: 361-373.
43. Xu, H., Wei, H., Tassone, F., Graw, S., Gardiner, K., and Weissman, S. M. (1995). A search for genes from the dark band regions of human chromosome 21. Genomics 27: 1-8.
44. Yaspo, M. L., Gellen, L., Mott, R., Korn, B., Nizetic, D., Poustka, A. M., and Lehrach, H. (1995). Model for a transcript map of human chromosome 21: Isolation of new coding sequences from exon and enriched cDNA libraries. Hum. Mol. Genet. 4: 1291-1304.
45. Yu, J., Tong, S., Shen, Y., and Kao, F. T. (1997). Gene identification and DNA sequence analysis in the GC-poor 20 megabase region of human chromosome 21. Proc. Natl. Acad. Sci. USA 94: 6862-6867.