Increased peripheral blood gamma delta T-cells in patients with lymphoid neoplasia: A diagnostic dilemma in flow cytometry

Communications in Clinical Cytometry

Volumn 38, Issue 6, 1999, Pages 280-285

  McClanahan, Julie ^a   Fukushima, Paula I ^a   Stetler Stevenson, Maryalice ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Gamma delta T cells; Immunophenotype; Non Hodgkin's lymphoma

Indexed keywords

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; DIAGNOSTIC ACCURACY; DIAGNOSTIC ERROR; DIAGNOSTIC VALUE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LYMPHATIC SYSTEM TUMOR; NATURAL KILLER CELL; NONHODGKIN LYMPHOMA; PRIORITY JOURNAL; T LYMPHOCYTE;

ADULT; AGED; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOENZYME TECHNIQUES; LEUKEMIA; LYMPHOCYTE COUNT; LYMPHOMA; MALE; MIDDLE AGED; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; T-LYMPHOCYTES;

EID: 0033572311     PISSN: 01964763     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0320(19991215)38:6<280::AID-CYTO4>3.0.CO;2-G     Document Type: Article

References (13)

1. Groh V, Porcelli S, Fabbi M, Lanier LL, Picker LJ, Anderson T, Warnke RA, Bhana AK, Strominger JL, Brenner MB. Human lymphocytes bearing T-cell receptor γδ-are phenotypically diverse and evenly distributed through out the lymphoid system. J Exp Med 1989;169: 1277-1294.
2. Raulet DH. The structure function and molecular genetics of the γδ-T-cell receptor. Ann Rev Immunol 1989;7:175-207.
3. Faure F, Miossec C, Jitsukawa S, Triebel F, Hercend T. The γδ-T-cell receptor expressed on human peripheral blood lymphocytes. Eur Cytokine Net 1990; 1:65-69.
4. Lefrancois L, Lecorre R, Mayo J, Bluestone JA, Goodman T. Extrathymic selection of TCR-γδ-T-cells by class II major histocompatibility complex molecules. Cell 1990;63:333-340.
5. Bluestone JA, Khattri R, Sciammas R, Sperling AI. TCR γδ-cells: a specialized T-cell subset in the immune system. Annu Rev Dev Biol 1995;11:307-353.
6. Schild H, Mavaddat N, Litzenberger C, et al. The nature of major histocompatibility complex recognotion by γδ-T-cells. Cell 1994;76: 29-37.
7. Blazar BR, Taylor PA, Bluestone JA, et al. Murine γδ-expressing T-cells affect alloengraftment via the recognition of nonclassical major histocompatibility complex class Ib antigens. Blood 1996;87:4463-4472.
8. Lamb LS, Henslee-Downey J, Parrish RS, Godder K, Thompson J, Lee C, Gee AP. Increased frequency of TCR γδ-+-T-cells in disease-free survivors following T cell-depleted partially mismatched related donor bone marrow transplantation for leukemia. J Hematotherapy 1996; 5:503-509.
9. Esslin A, Formby B. Comparison of cytolytic and proliferative activities of human γδ-and-αβ-T-cells from peripheral blood against human tumor cell lines. J Natl Cancer Inst 1991;153:1564-1569.
10. Bucy RP, Chen CL, Cooper M. Tissue localization and CD8 accessory molecule expression of T γδ-cells in humans. J Immunol 1989;142: 3045-3049.
11. Cooke CB, Krenacs L, Stetler-Stevenson M, Greiner TC, Raffeld M, Kingma DW, Abruzzo L, Frantz C, Kaviani M, Jaffe ES. Hepatosplenic T-cell lymphoma: a distinct clinicopathologic entity of cytotoxic γδ-T-cell origin. Blood 1996; 88:4265-4274.
12. Arnulf B, Copie-Bergman C, Delfau-Larue M, Lavergne-Slove A, Bosq J, Wechsler J, Wassef M, Matuchansky C, Epardeau B, Stern M, Bagot M, Reyes F, Gaulard P. Nonhepatosplenic γδ-T-cell lymphoma: a subset of cytotoxic lymphomas with mucosal or skin localization. Blood 1998;91:1723-1731.
13. Kuchnio M, Sausville EA, Jaffe ES, Greiner T, Foss FM, McClanahan J, Fukushima P, Stetler-Stevenson M. Flow cytomctric detection of neoplastic T-cells in patients with mycosis fungoides based upon levels of T-cell receptor expression. Am J Clin Pathol 1994;102:856-860.