Seccadic dysmetria and adaptation after lesions of the cerebellar cortex

Journal of Neuroscience

Volumn 19, Issue 24, 1999, Pages 10931-10939

  Barash, Shabtai ^a   Melikyan, Armenuhi ^a   Sivakov, Alexey ^a   Zhang, Mingsha ^a   Glickstein, Mitchell ^b   Thier, Peter ^c  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

Author keywords

Cerebellar cortex; Cerebellum; Dysmetria; Eye movement; Fatigue; Lesion; Motor learning; Recovery; Recovery from brain damage; Saccades; Saccadic adaptation; Saccadic eye movement; Vermis

Indexed keywords

ADAPTATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CEREBELLUM CORTEX; CEREBELLUM INJURY; CEREBELLUM VERMIS; CONTROLLED STUDY; DYSMETRIA; EYE MOVEMENT CONTROL; MALE; MONKEY; MOTOR PERFORMANCE; MUSCLE FATIGUE; NONHUMAN; OCULOMOTOR NERVE; PRIORITY JOURNAL; SACCADIC EYE MOVEMENT; ANIMAL; CEREBELLAR ATAXIA; CEREBELLUM DISEASE; EXTRAOCULAR MUSCLE; MACACA; PATHOLOGY; PATHOPHYSIOLOGY; REFERENCE VALUE;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; CEREBELLAR ATAXIA; CEREBELLAR CORTEX; CEREBELLAR DISEASES; MACACA FASCICULARIS; MALE; MUSCLE FATIGUE; OCULOMOTOR MUSCLES; REFERENCE VALUES; SACCADES;

EID: 0033571982     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.19-24-10931.1999     Document Type: Article

References (30)

1. Albano JE, King WM (1989) Rapid adaptation of saccadic amplitude in humans and monkeys. Invest Ophthalmol Vis Sci 30:1883-1893.
2. Aschoff JC, Cohen B (1971) Changes in saccadic eye movements produced by cerebellar cortical lesions. Exp Neurol 32:123-133.
3. Barash S, Melikyan A, Sivakov A, Tauber M (1998) Shift of visual fixation dependent on background illumination. J Neurophysiol 79:2766-2781.
4. Botzel K, Rottach K, Buettner U (1993) Normal and pathological saccadic dysmetria. Brain 116:337-353.
5. Buettner U, Fuhry L (1995) Eye movements. Curr Opin Neurol 8:77-82.
6. Fitzgibbon EJ, Goldberg ME, Segraves MA (1986) Short term saccadic adaptation in the monkey. In: Adaptive processes in visual and oculomotor systems (Keller BL, Zee DS, eds), pp 329-333. Oxford: Pergamon.
7. Fujikado T, Noda H (1987) Saccadic eye movements evoked by microstimulation of lobule VII of the cerebellar vermis of macaque monkeys. J Physiol (Lond) 394:573-594.
8. Glickstein M (1992) The cerebellum and motor learning. Curr Opin Neurobiol 2:802-806.
9. Goldberg ME, Musil SY, Fitzgibbon EJ, Smith M, Olson CR (1993) The role of the cerebellum in the control of saccadic eye movements. In: Role of the cerebellum and basal ganglia in voluntary movement (Mano N, Hamada I, DeLong MR, eds), pp 203-211. Amsterdam: Elsevier Science.
10. Ito M (1998) Cerebellar learning in the vestibulo-ocular reflex. Trends Cognit Sci 2:313-321.
11. Judge SJ, Richmond BJ, Chu FC (1980) Implantation of magnetic search coils for measurement of eye position: an improved method. Vision Res 20:535-538.
12. Kommerell G, Olivier D, Theopold H (1976) Adaptive programming of phasic and tonic components in saccadic eye movements. Investigations of patients with abducens palsy. Invest Ophthalmol 15:657-660.
13. Leigh RJ, Zee DS (1990) The neurology of eye movements. Philadelphia: Davis.
14. Madigan JrJC, Carpenter MB (1971) Cerebellum of the rhesus monkey. Baltimore: University Park.
15. McLaughlin SC (1967) Parametric adjustment in saccadic eye movements. Percept Psychophys 2:359-362.
16. Noda H, Fujikado T (1987a) Topography of the oculomotor area of the cerebellar vermis in macaques as determined by microstimulation. J Neurophysiol 58:359-378.
17. Noda H, Fujikado T (1987b) Involvement of Purkinje cells in evoking saccadic eye movements by microstimulation of the posterior cerebellar vermis of monkeys. J Neurophysiol 57:1247-1261.
18. Ohtsuka K, Noda H (1995) Discharge properties of Purkinje cells in the oculomotor vermis during visually guided saccades in the macaque monkey. J Neurophysiol 74:1828-1840.
19. Optican LM, Robinson DA (1980) Cerebellar-dependent adaptive control of primate saccadic system. J Neurophysiol 44:1058-1076.
20. Raymond JL, Lisberger SG, Mauk MD (1996) The cerebellum: a neuronal learning machine? Science 272:1126-1131.
21. Ritchie L (1976) Effects of cerebellar lesions on saccadic eye movements. J Neurophysiol 39:1246-1256.
22. Robinson FR (1995) Role of the cerebellum in movement control and adaptation. Curr Opin Neurobiol 5:755-762.
23. Robinson FR, Straube A, Fuchs AF (1993) Role of the caudal fastigial nucleus in saccade generation. II. Effects of muscimol inactivation. J Neurophysiol 70:1741-1758.
24. Ron S, Robinson DA (1973) Eye movements evoked by cerebellar stimulation in the alert monkey. J Neurophysiol 36:1004-1022.
25. Sato H, Noda H (1992) Saccadic dysmetria induced by transient functional decortication of the cerebellar vermis. Exp Brain Res [Erratum 89:690] 88:455-458.
26. Scudder CA, Batourina EY, Tunder GS (1998) Comparison of two methods of producing adaptation of saccade size and implications for the site of plasticity J Neurophysiol 79:704-715.
27. Straube A, Fuchs AF, Usher S, Robinson FR (1997) Characteristics of saccadic gain adaptation in rhesus macaques. J Neurophysiol 77:874-895.
28. Takagi M, Zee DS, Tamargo RJ (1998) Effects of lesions of the oculomotor vermis on eye movements in primate: saccades. J Neurophysiol 80:1911-1931.
29. Thompson RF, Bao S, Chen L, Cipriano BD, Grethe JS, Kim JJ, Thompson JK, Tracy JA, Weninger MS, Krupa DJ (1997) Associative learning. Int Rev Neurobiol 41:151-189.
30. Yamada J, Noda H (1987) Afferent and efferent connections of the oculomotor cerebellar vermis in the macaque monkey. J Comp Neurol 265:224-241.