Efficient antibody diversification by gene conversion in vivo in the absence of selection for V(D)J-encoded determinants

EMBO Journal

Volumn 18, Issue 22, 1999, Pages 6319-6328

  Sayegh, Camil E ^a   Drury, Gillian ^a   Ratcliffe, Michael J H ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

B cell development; Bursa of Fabricius; Gene conversion; Immunoglobulin light chain; V(D)J recombination

Indexed keywords

IMMUNOGLOBULIN LIGHT CHAIN;

ANIMAL CELL; ANTIGEN SPECIFICITY; ARTICLE; BURSA FABRICII; CONTROLLED STUDY; GENE CONVERSION; IMMUNOGLOBULIN GENE; IMMUNOGLOBULIN VARIABLE REGION; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; PSEUDOGENE;

ANIMALS; ANTIBODY DIVERSITY; BASE SEQUENCE; BURSA OF FABRICIUS; CHICK EMBRYO; CHICKENS; GENE CONVERSION; GENE REARRANGEMENT; GENES, IMMUNOGLOBULIN; IMMUNOGLOBULIN LIGHT CHAINS; IMMUNOGLOBULIN MU-CHAINS; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; PSEUDOGENES; RECEPTORS, ANTIGEN, B-CELL; RESTRICTION MAPPING; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, NUCLEIC ACID; TRANSFECTION;

ANIMALIA; FABRICIUS;

EID: 0033571586     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/18.22.6319     Document Type: Article

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