Total synthesis of everninomicin 13,384-1 - Part 3: Synthesis of the DE fragment and completion of the total synthesis

Angewandte Chemie - International Edition

Volumn 38, Issue 22, 1999, Pages 3345-3350

  Nicolaou, K C ^a,b   Mitchell, Helen J ^a,b   Rodríguez, Rosa María ^a,b   Fylaktakidou, Konstantina C ^a,b   Suzuki, Hideo ^a,b  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Antibiotics; Carbohydrates; Everninomicin; Glycosylations; Total synthesis

Indexed keywords

ANTIBIOTIC AGENT; EVERNINOMYCIN; UNCLASSIFIED DRUG;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; GLYCOSYLATION; REACTION ANALYSIS;

EID: 0033571255     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-3773(19991115)38:22<3345::AID-ANIE3345>3.0.CO;2-9     Document Type: Article

References (21)

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2. K. C. Nicolaou, H. J. Mitchell, H. Suzuki, R. M. Rodríguez, O. Baudoin, K. C. Fylaktakidou, Angew. Chem. 1999, 111, 3523-3528; Angew. Chem. Int. Ed. 1999, 38, 3334-3339.
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11. Compound 26 was identical with an authentic sample obtained by degradation of everninomicin 13,384-1 (1). Details of this and other degradation studies will be reported in later publications.
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21. All new compounds exhibited satisfactory spectral and exact mass data.