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Volumn 161, Issue 1, 1999, Pages 50-58

Axonal neurofilaments are nonessential elements of toxicant-induced reductions in fast axonal transport: Video-enhanced differential interference microscopy in peripheral nervous system axons

Author keywords

2,5 hexanedione; Acrylamide; Fast axonal transport; Neurofilaments; Peripheral nervous system

Indexed keywords

ACETONYLACETONE; ACRYLAMIDE;

EID: 0033571227     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.1999.8780     Document Type: Article
Times cited : (24)

References (62)
  • 2
    • 0019849712 scopus 로고
    • Video-enhanced contrast, differential interference contrast (AVEC-DIC) microscopy: A new method capable of analyzing microtubule-related motility in the reticulopodial network of Allogromia laticollaris
    • Allen R. D., Allen N. S., Travis J. L. Video-enhanced contrast, differential interference contrast (AVEC-DIC) microscopy: A new method capable of analyzing microtubule-related motility in the reticulopodial network of Allogromia laticollaris. Cell Motil. 1:1981;291-302.
    • (1981) Cell Motil. , vol.1 , pp. 291-302
    • Allen, R.D.1    Allen, N.S.2    Travis, J.L.3
  • 3
    • 0021027622 scopus 로고
    • The effect of 3,4-dimethyl substitution on the neurotoxicity of 2,5-hexanedione. I. Accelerated clinical neuropathy is accompanied by more proximal axonal swellings
    • Anthony D. C., Boekelheide K., Graham D. G. The effect of 3,4-dimethyl substitution on the neurotoxicity of 2,5-hexanedione. I. Accelerated clinical neuropathy is accompanied by more proximal axonal swellings. Toxicol. Appl. Pharmacol. 71:1983a;362-371.
    • (1983) Toxicol. Appl. Pharmacol. , vol.71 , pp. 362-371
    • Anthony, D.C.1    Boekelheide, K.2    Graham, D.G.3
  • 4
    • 0014210026 scopus 로고
    • Peripheral neuropathy with sympathetic overactivity from industrial contact with acrylamide
    • Auld R. B., Bedwell S. F. Peripheral neuropathy with sympathetic overactivity from industrial contact with acrylamide. Can. Med. Assoc. J. 96:1967;652-654.
    • (1967) Can. Med. Assoc. J. , vol.96 , pp. 652-654
    • Auld, R.B.1    Bedwell, S.F.2
  • 5
    • 0021894565 scopus 로고
    • Video microscopy of fast axonal transport in extruded axoplasm: A new model for study of molecular mechanisms
    • Brady S. T., Lasek R. J., Allen R. D. Video microscopy of fast axonal transport in extruded axoplasm: A new model for study of molecular mechanisms. Cell Motil. 5:1985;81-101.
    • (1985) Cell Motil. , vol.5 , pp. 81-101
    • Brady, S.T.1    Lasek, R.J.2    Allen, R.D.3
  • 6
    • 0025021497 scopus 로고
    • A monoclonal antibody against kinesin inhibits both anterograde and retrograde fast axonal transport in squid axoplasm
    • Brady S. T., Pfister K. K., Bloom G. S. A monoclonal antibody against kinesin inhibits both anterograde and retrograde fast axonal transport in squid axoplasm. Proc. Natl. Acad. Sci. USA. 87:1990;1061-1065.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 1061-1065
    • Brady, S.T.1    Pfister, K.K.2    Bloom, G.S.3
  • 7
    • 0027287359 scopus 로고
    • Acrylamide and glycidamide impair outgrowth in differentiating N1E.115 neuroblastoma without disturbing rapid bi-directional transport of organelles observed by video microscopy
    • Brat D. J., Brimijoin S. Acrylamide and glycidamide impair outgrowth in differentiating N1E.115 neuroblastoma without disturbing rapid bi-directional transport of organelles observed by video microscopy. J. Neurochem. 60:1993;2145-2152.
    • (1993) J. Neurochem. , vol.60 , pp. 2145-2152
    • Brat, D.J.1    Brimijoin, S.2
  • 8
    • 0000494564 scopus 로고
    • The significance of the "dying-back" process in experimental and human neurological disease
    • Cavanagh J. B. The significance of the "dying-back" process in experimental and human neurological disease. Int. Rev. Exp. Pathol. 3:1964;219-267.
    • (1964) Int. Rev. Exp. Pathol. , vol.3 , pp. 219-267
    • Cavanagh, J.B.1
  • 9
    • 0029743539 scopus 로고    scopus 로고
    • Decreased GAP-43 accumulation in neurite tips of cultured hippocampal neurons by acrylamide
    • Clarke C. H., Sickles D. W. Decreased GAP-43 accumulation in neurite tips of cultured hippocampal neurons by acrylamide. Neurotoxicology. 17:1996;397-406.
    • (1996) Neurotoxicology , vol.17 , pp. 397-406
    • Clarke, C.H.1    Sickles, D.W.2
  • 10
    • 0022336953 scopus 로고
    • Molecular mechanisms of diketone neurotoxicity
    • DeCaprio A. P. Molecular mechanisms of diketone neurotoxicity. Chem.-Biol. Interact. 54:1985;257-270.
    • (1985) Chem.-Biol. Interact. , vol.54 , pp. 257-270
    • Decaprio, A.P.1
  • 11
    • 0020384150 scopus 로고
    • Covalent binding of a neurotoxic n-hexane metabolite: Conversion of primary amines to substituted pyrrole adducts by 2,5-hexanedione
    • DeCaprio A. P., Olajos E. J., Weber P. Covalent binding of a neurotoxic n-hexane metabolite: Conversion of primary amines to substituted pyrrole adducts by 2,5-hexanedione. Toxicol. Appl. Pharmacol. 65:1982;440-450.
    • (1982) Toxicol. Appl. Pharmacol. , vol.65 , pp. 440-450
    • Decaprio, A.P.1    Olajos, E.J.2    Weber, P.3
  • 12
    • 0028261670 scopus 로고
    • Neurofilament-deficient axons and perikaryal aggregates in viable transgenic mice expressing a neurofilament-β-galactosidase fusion protein
    • Eyer J., Peterson A. Neurofilament-deficient axons and perikaryal aggregates in viable transgenic mice expressing a neurofilament-β-galactosidase fusion protein. Neuron. 12:1994;1-20.
    • (1994) Neuron , vol.12 , pp. 1-20
    • Eyer, J.1    Peterson, A.2
  • 13
    • 0014219981 scopus 로고
    • Six cases of acrylamide poisoning
    • Garland T. O., Patterson M. W. H. Six cases of acrylamide poisoning. Br. Med. J. 10/21:1967;134-138.
    • (1967) Br. Med. J. , vol.1021 , pp. 134-138
    • Garland, T.O.1    Patterson, M.W.H.2
  • 14
    • 0016786349 scopus 로고
    • The nerve cell response to axotomy
    • Grafstein B. The nerve cell response to axotomy. Exp. Neurol. 48:1975;32-51.
    • (1975) Exp. Neurol. , vol.48 , pp. 32-51
    • Grafstein, B.1
  • 15
    • 0019312427 scopus 로고
    • Hexane neuropathy: A proposal for pathogenesis of a hazard of occupational exposure and inhalant abuse
    • Graham D. G. Hexane neuropathy: A proposal for pathogenesis of a hazard of occupational exposure and inhalant abuse. Chem.-Biol. Interact. 32:1980;339-345.
    • (1980) Chem.-Biol. Interact. , vol.32 , pp. 339-345
    • Graham, D.G.1
  • 16
    • 0020260658 scopus 로고
    • In vitro and in vivo studies of the molecular pathogenesis of n-hexane neuropathy
    • Graham D. G., Anthony D. C., Boekelheide K. In vitro and in vivo studies of the molecular pathogenesis of n-hexane neuropathy. Neurobehav. Toxicol. Teratol. 4:1982;629-634.
    • (1982) Neurobehav. Toxicol. Teratol. , vol.4 , pp. 629-634
    • Graham, D.G.1    Anthony, D.C.2    Boekelheide, K.3
  • 17
    • 0021258573 scopus 로고
    • In vitro evidence that covalent crosslinking of neurofilaments occurs in gamma-diketone neuropathy
    • Graham D. G., Szakal-Quin G., Priest J. W., Anthony D. C. In vitro evidence that covalent crosslinking of neurofilaments occurs in gamma-diketone neuropathy. Proc. Natl. Acad. Sci. USA. 81:1984;4979-4982.
    • (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 4979-4982
    • Graham, D.G.1    Szakal-Quin, G.2    Priest, J.W.3    Anthony, D.C.4
  • 18
    • 0345221537 scopus 로고
    • Axonal transport in neurotoxic disorders
    • Griffin J. W. Axonal transport in neurotoxic disorders. Comments Toxicol. 3:1989;405-426.
    • (1989) Comments Toxicol. , vol.3 , pp. 405-426
    • Griffin, J.W.1
  • 19
    • 0018126621 scopus 로고
    • Slow axonal transport of neurofilament proteins: Impairment by β,β′-iminodipropionitrile administration
    • Griffin J. W., Hoffman P. N., Clark A. W., Carroll P. T., Price D. L. Slow axonal transport of neurofilament proteins: Impairment by β,β′-iminodipropionitrile administration. Science. 202:1978;633-635.
    • (1978) Science , vol.202 , pp. 633-635
    • Griffin, J.W.1    Hoffman, P.N.2    Clark, A.W.3    Carroll, P.T.4    Price, D.L.5
  • 20
    • 0028175589 scopus 로고
    • Toxic neurofilamentous axonopathies and fast anterograde axonal transport. V. Reduced bi-directional vesicle transport in cultured neurons by acrylamide and glycidamide
    • Harris C. H., Gulati A. K., Friedman M. A., Sickles D. W. Toxic neurofilamentous axonopathies and fast anterograde axonal transport. V. Reduced bi-directional vesicle transport in cultured neurons by acrylamide and glycidamide. J. Toxicol. Environ. Health. 42:1994;343-356.
    • (1994) J. Toxicol. Environ. Health , vol.42 , pp. 343-356
    • Harris, C.H.1    Gulati, A.K.2    Friedman, M.A.3    Sickles, D.W.4
  • 21
    • 0024538867 scopus 로고
    • Acrylamide-induced increases in deposition of axonally transported glycoproteins in rat sciatic nerve
    • Harry G. J., Goodrum J. F., Bouldin T. W., Toews A. D., Morell P. Acrylamide-induced increases in deposition of axonally transported glycoproteins in rat sciatic nerve. J. Neurochem. 52:1989;1240-1247.
    • (1989) J. Neurochem. , vol.52 , pp. 1240-1247
    • Harry, G.J.1    Goodrum, J.F.2    Bouldin, T.W.3    Toews, A.D.4    Morell, P.5
  • 22
    • 0016259147 scopus 로고
    • Characteristics of the retrograde axonal transport system for nerve growth factor in the sympathetic nervous system
    • Hendry I. A., Stach R., Herrup K. Characteristics of the retrograde axonal transport system for nerve growth factor in the sympathetic nervous system. Brain Res. 82:1974;117-128.
    • (1974) Brain Res. , vol.82 , pp. 117-128
    • Hendry, I.A.1    Stach, R.2    Herrup, K.3
  • 23
    • 0032559260 scopus 로고    scopus 로고
    • Kinesin and dynein superfamily proteins and the mechanism of organelle transport
    • Hirokawa N. Kinesin and dynein superfamily proteins and the mechanism of organelle transport. Science. 279:1998;519-526.
    • (1998) Science , vol.279 , pp. 519-526
    • Hirokawa, N.1
  • 24
    • 0020683090 scopus 로고
    • Early and dose dependent decrease of retrograde axonal transport in acrylamide intoxicated rats
    • Jakobsen J., Sidenius P. Early and dose dependent decrease of retrograde axonal transport in acrylamide intoxicated rats. J. Neurochem. 40:1983;447-454.
    • (1983) J. Neurochem. , vol.40 , pp. 447-454
    • Jakobsen, J.1    Sidenius, P.2
  • 26
  • 28
    • 0023833599 scopus 로고
    • A comparison of the effects of acrylamide and experimental diabetes on the retrograde axonal transport of proteins in the rat sciatic nerve: Analysis by two-dimensional polyacrylamide gel
    • Logan M. J., McLean W. G. A comparison of the effects of acrylamide and experimental diabetes on the retrograde axonal transport of proteins in the rat sciatic nerve: Analysis by two-dimensional polyacrylamide gel. J. Neurochem. 50:1988;183-189.
    • (1988) J. Neurochem. , vol.50 , pp. 183-189
    • Logan, M.J.1    McLean, W.G.2
  • 29
    • 0009968987 scopus 로고
    • A quantitation of fast axonal transport in cultured chick dorsal root ganglion (DRG) explants following exposure to acrylamide (ACR), methacrylamide (M-ACR) and cyanide
    • Martenson C. H., Anthony D. C., Sheetz M. P., Graham D. G. A quantitation of fast axonal transport in cultured chick dorsal root ganglion (DRG) explants following exposure to acrylamide (ACR), methacrylamide (M-ACR) and cyanide. Toxicologist. 12:1992;191.
    • (1992) Toxicologist , vol.12 , pp. 191
    • Martenson, C.H.1    Anthony, D.C.2    Sheetz, M.P.3    Graham, D.G.4
  • 30
    • 0029039138 scopus 로고
    • The effect of acrylamide and other sulfhydryl alkylators on the ability of dynein and kinesin to translocate microtubules in vitro
    • Martenson C. H., Odom A., Sheetz M. P., Graham D. G. The effect of acrylamide and other sulfhydryl alkylators on the ability of dynein and kinesin to translocate microtubules in vitro. Toxicol. Appl. Pharmacol. 133:1995;73-81.
    • (1995) Toxicol. Appl. Pharmacol. , vol.133 , pp. 73-81
    • Martenson, C.H.1    Odom, A.2    Sheetz, M.P.3    Graham, D.G.4
  • 31
    • 0020523741 scopus 로고
    • Altered retrograde axonal transport of nerve growth factor after single and repeated doses of acrylamide in the rat
    • Miller M. S., Miller M. J., Burks T. F., Sipes I. G. Altered retrograde axonal transport of nerve growth factor after single and repeated doses of acrylamide in the rat. Toxicol. Appl. Pharmacol. 69:1983;96-101.
    • (1983) Toxicol. Appl. Pharmacol. , vol.69 , pp. 96-101
    • Miller, M.S.1    Miller, M.J.2    Burks, T.F.3    Sipes, I.G.4
  • 32
    • 0021686752 scopus 로고
    • Single doses of acrylamide reduce retrograde transport velocity
    • Miller M. S., Spencer P. S. Single doses of acrylamide reduce retrograde transport velocity. J. Neurochem. 43:1984;1401-1408.
    • (1984) J. Neurochem. , vol.43 , pp. 1401-1408
    • Miller, M.S.1    Spencer, P.S.2
  • 34
    • 0023838603 scopus 로고
    • Progressive deficits in retrograde axon transport precede degeneration of motor axons in acrylamide neuropathy
    • Moretto A., Sabri M. I. Progressive deficits in retrograde axon transport precede degeneration of motor axons in acrylamide neuropathy. Brain Res. 440:1988;18-24.
    • (1988) Brain Res. , vol.440 , pp. 18-24
    • Moretto, A.1    Sabri, M.I.2
  • 35
    • 0027182382 scopus 로고
    • Direct measurement of fast axonal organelle transport in the sciatic nerve of rats treated with acrylamide
    • Padilla S., Atkinson M. B., Breuer A. C. Direct measurement of fast axonal organelle transport in the sciatic nerve of rats treated with acrylamide. J. Toxicol. Environ. Health. 39:1993;429-445.
    • (1993) J. Toxicol. Environ. Health , vol.39 , pp. 429-445
    • Padilla, S.1    Atkinson, M.B.2    Breuer, A.C.3
  • 36
    • 0020361510 scopus 로고
    • Redistribution of proteins of fast axonal transport following administration of β,β′-iminodipropionitrile: A quantitative autoradiographic study
    • Papasozemenos S. C. H., Yoon M., Crane R., Autilio-Gambetti L. Redistribution of proteins of fast axonal transport following administration of β,β′-iminodipropionitrile: A quantitative autoradiographic study. J. Cell Biol. 95:1982;672-675.
    • (1982) J. Cell Biol. , vol.95 , pp. 672-675
    • Papasozemenos, S.C.H.1    Yoon, M.2    Crane, R.3    Autilio-Gambetti, L.4
  • 37
    • 0023205148 scopus 로고
    • Retrograde transport by the microtubule associated protein MAP 1C
    • Paschal B. M., Vallee R. B. Retrograde transport by the microtubule associated protein MAP 1C. Nature. 330:1987;181-183.
    • (1987) Nature , vol.330 , pp. 181-183
    • Paschal, B.M.1    Vallee, R.B.2
  • 38
    • 0024425922 scopus 로고
    • Modification of the microtubule-binding and ATPase activities of kinesin by N-ethylmaleimide (NEM) suggests a role of sulfhydryls in fast axonal transport
    • Pfister K. K., Wagner M. C., Bloom G. S., Brady S. T. Modification of the microtubule-binding and ATPase activities of kinesin by N-ethylmaleimide (NEM) suggests a role of sulfhydryls in fast axonal transport. Biochemistry. 28:1989;9006-9012.
    • (1989) Biochemistry , vol.28 , pp. 9006-9012
    • Pfister, K.K.1    Wagner, M.C.2    Bloom, G.S.3    Brady, S.T.4
  • 39
    • 0014591401 scopus 로고
    • The pathogensis of dying-back polyneuropathies. Part 2. An ultrastructural study of experimental acrylamide intoxication in the cat
    • Prineas J. The pathogensis of dying-back polyneuropathies. Part 2. An ultrastructural study of experimental acrylamide intoxication in the cat. J. Neuropathol. Exp. Neurol. 28:1969;598-621.
    • (1969) J. Neuropathol. Exp. Neurol. , vol.28 , pp. 598-621
    • Prineas, J.1
  • 40
    • 0027514882 scopus 로고
    • Determination of acrylamide in rat serum and sciatic nerve by gas chromatography-electron-capture detection
    • Raymer J. H., Sparacino C. M., Velez G. R., Padilla S., MacPhail R. C., Crofton K. M. Determination of acrylamide in rat serum and sciatic nerve by gas chromatography-electron-capture detection. J. Chromatogr. 619:1993;223-234.
    • (1993) J. Chromatogr. , vol.619 , pp. 223-234
    • Raymer, J.H.1    Sparacino, C.M.2    Velez, G.R.3    Padilla, S.4    MacPhail, R.C.5    Crofton, K.M.6
  • 41
    • 0028085087 scopus 로고
    • Microtubules with altered assembly kinetics have a decreased rate of kinesin-based transport
    • Redenbach D. M., Richburg J. H., Boekelheide K. Microtubules with altered assembly kinetics have a decreased rate of kinesin-based transport. Cell Motil. Cytoskel. 26:1993;79-87.
    • (1993) Cell Motil. Cytoskel. , vol.26 , pp. 79-87
    • Redenbach, D.M.1    Richburg, J.H.2    Boekelheide, K.3
  • 42
    • 0019414655 scopus 로고
    • Acrylamide and 2,5-hexanedione neuropathies: Abnormal bi-directional transport rate in distal axons
    • Sahenk Z., Mendell J. R. Acrylamide and 2,5-hexanedione neuropathies: Abnormal bi-directional transport rate in distal axons. Brain Res. 219:1981;397-405.
    • (1981) Brain Res. , vol.219 , pp. 397-405
    • Sahenk, Z.1    Mendell, J.R.2
  • 43
    • 0022370229 scopus 로고
    • Pathogenesis of experimental giant neurofilamentous axonopathies: A unified hypothesis based on chemical modification of neurofilaments
    • Sayre L. M., Autilio-Gambetti L., Gambetti P. Pathogenesis of experimental giant neurofilamentous axonopathies: A unified hypothesis based on chemical modification of neurofilaments. Brain Res. Rev. 10:1985;69-83.
    • (1985) Brain Res. Rev. , vol.10 , pp. 69-83
    • Sayre, L.M.1    Autilio-Gambetti, L.2    Gambetti, P.3
  • 44
    • 0016380524 scopus 로고
    • Ultrastructural studies of the dying-back process. I. Peripheral nerve terminal and axon degeneration in systemic acrylamide intoxication
    • Schaumburg H. H., Wisniewski H. M., Spencer P. S. Ultrastructural studies of the dying-back process. I. Peripheral nerve terminal and axon degeneration in systemic acrylamide intoxication. J. Neuropathol. Exp. Neurol. 33:1974;260-284.
    • (1974) J. Neuropathol. Exp. Neurol. , vol.33 , pp. 260-284
    • Schaumburg, H.H.1    Wisniewski, H.M.2    Spencer, P.S.3
  • 45
    • 0024317171 scopus 로고
    • Toxic neurofilamentous axonopathies and fast anterograde axonal transport. I. The effects of single doses of acrylamide on the rate and capacity of transport
    • Sickles D. W. Toxic neurofilamentous axonopathies and fast anterograde axonal transport. I. The effects of single doses of acrylamide on the rate and capacity of transport. Neurotoxicology. 10:1989a;91-102.
    • (1989) Neurotoxicology , vol.10 , pp. 91-102
    • Sickles, D.W.1
  • 46
    • 0024372799 scopus 로고
    • Toxic neurofilamentous axonopathies and fast anterograde axonal transport. II. The effects of single doses of neurotoxic and non-neurotoxic diketones and β,β′-iminodipropionitrile (IDPN) on the rate and capacity of transport
    • Sickles D. W. Toxic neurofilamentous axonopathies and fast anterograde axonal transport. II. The effects of single doses of neurotoxic and non-neurotoxic diketones and β,β′-iminodipropionitrile (IDPN) on the rate and capacity of transport. Neurotoxicology. 10:1989b;103-112.
    • (1989) Neurotoxicology , vol.10 , pp. 103-112
    • Sickles, D.W.1
  • 47
    • 0025804701 scopus 로고
    • Toxic neurofilamentous axonopathies and fast anterograde axonal transport. III. Recovery from single injections and multiple dosing effects of acrylamide and 2,5-hexanedione
    • Sickles D. W. Toxic neurofilamentous axonopathies and fast anterograde axonal transport. III. Recovery from single injections and multiple dosing effects of acrylamide and 2,5-hexanedione. Toxicol. Appl. Pharmacol. 108:1991;390-396.
    • (1991) Toxicol. Appl. Pharmacol. , vol.108 , pp. 390-396
    • Sickles, D.W.1
  • 48
    • 0026694407 scopus 로고
    • Toxic neurofilamentous axonopathies and fast anterograde axonal transport. IV. In vitro analysis of transport following acrylamide and 2,5-hexanedione
    • Sickles D. W. Toxic neurofilamentous axonopathies and fast anterograde axonal transport. IV. In vitro analysis of transport following acrylamide and 2,5-hexanedione. Toxicol. Lett. 61:1992;199-204.
    • (1992) Toxicol. Lett. , vol.61 , pp. 199-204
    • Sickles, D.W.1
  • 49
    • 0029763904 scopus 로고    scopus 로고
    • Direct effect of the neurotoxicant acrylamide on kinesin-based microtubule motility
    • Sickles D. W., Brady S. T., Testino A., Friedman M. A., Wrenn R. A. Direct effect of the neurotoxicant acrylamide on kinesin-based microtubule motility. J. Neurosci. Res. 46:1996;7-17.
    • (1996) J. Neurosci. Res. , vol.46 , pp. 7-17
    • Sickles, D.W.1    Brady, S.T.2    Testino, A.3    Friedman, M.A.4    Wrenn, R.A.5
  • 51
    • 74049096133 scopus 로고    scopus 로고
    • 2,5-Hexanedione directly affects kinesin-based microtubule motility
    • Sickles D. W., Tsai J. 2,5-Hexanedione directly affects kinesin-based microtubule motility. Toxicologist. 30:1996;302.
    • (1996) Toxicologist , vol.30 , pp. 302
    • Sickles, D.W.1    Tsai, J.2
  • 52
    • 0009968990 scopus 로고    scopus 로고
    • Acrylamide produces a temporal and correlative decrease in fast anterogradely transported proteins in neuromuscular junctions
    • Sickles D. W., Tsai N., Padilla S. Acrylamide produces a temporal and correlative decrease in fast anterogradely transported proteins in neuromuscular junctions. Toxicologist. 37:1998;107.
    • (1998) Toxicologist , vol.37 , pp. 107
    • Sickles, D.W.1    Tsai, N.2    Padilla, S.3
  • 53
    • 0020682413 scopus 로고
    • Anterograde axonal transport in rats during intoxication with acrylamide
    • Sidenius P., Jakobsen J. Anterograde axonal transport in rats during intoxication with acrylamide. J. Neurochem. 40:1983;697-704.
    • (1983) J. Neurochem. , vol.40 , pp. 697-704
    • Sidenius, P.1    Jakobsen, J.2
  • 54
    • 0018194601 scopus 로고
    • On the specific molecular configuration of neurotoxic aliphatic hexacarbon compounds causing central-peripheral distal axonopathy
    • Spencer P. S., Bischoff M. C., Schaumburg H. H. On the specific molecular configuration of neurotoxic aliphatic hexacarbon compounds causing central-peripheral distal axonopathy. Toxicol. Appl. Pharmacol. 44:1978;17-28.
    • (1978) Toxicol. Appl. Pharmacol. , vol.44 , pp. 17-28
    • Spencer, P.S.1    Bischoff, M.C.2    Schaumburg, H.H.3
  • 55
    • 0016135987 scopus 로고
    • A review of acrylamide neurotoxicity Part 1. Properties, uses and human exposure
    • Spencer P. S., Schaumburg H. H. A review of acrylamide neurotoxicity Part 1. Properties, uses and human exposure. Can. J. Neurol. Sci. 1:1974;143-150.
    • (1974) Can. J. Neurol. Sci. , vol.1 , pp. 143-150
    • Spencer, P.S.1    Schaumburg, H.H.2
  • 56
    • 0000290933 scopus 로고
    • Central-peripheral distal axonopathy - The pathology of dying-back polyneuropathies
    • Spencer P. S., Schaumburg H. H. Central-peripheral distal axonopathy - The pathology of dying-back polyneuropathies. Prog. Neuropathol. 3:1976;253-295.
    • (1976) Prog. Neuropathol. , vol.3 , pp. 253-295
    • Spencer, P.S.1    Schaumburg, H.H.2
  • 57
    • 0017364389 scopus 로고
    • Ultrastructural studies of the dying back process. IV. Differential vulnerability of PNS and CNS fibers in experimental central-peripheral distal axonopathies
    • Spencer P. S., Schaumburg H. H. Ultrastructural studies of the dying back process. IV. Differential vulnerability of PNS and CNS fibers in experimental central-peripheral distal axonopathies. J. Neuropathol. Exp. Neurol. 36:1977;300-320.
    • (1977) J. Neuropathol. Exp. Neurol. , vol.36 , pp. 300-320
    • Spencer, P.S.1    Schaumburg, H.H.2
  • 58
    • 0016612705 scopus 로고
    • Nervous system degeneration produced by the industrial solvent methyl n-buthyl ketone
    • Spencer P. S., Schaumburg H. H., Raleigh R. L., Terhaar C. J. Nervous system degeneration produced by the industrial solvent methyl n-buthyl ketone. Arch. Neurol. 32:1975;219-222.
    • (1975) Arch. Neurol. , vol.32 , pp. 219-222
    • Spencer, P.S.1    Schaumburg, H.H.2    Raleigh, R.L.3    Terhaar, C.J.4
  • 60
    • 0345221530 scopus 로고    scopus 로고
    • Axonal neurofilaments are non-essential elements of toxicant-induced reductions in fast axonal transport I. Radiolabeling in CNS axons
    • Stone J. D., Peterson A. P., Eyer J., Sickles D. W. Axonal neurofilaments are non-essential elements of toxicant-induced reductions in fast axonal transport I. Radiolabeling in CNS axons. Neurotoxicology. 1999b.
    • (1999) Neurotoxicology
    • Stone, J.D.1    Peterson, A.P.2    Eyer, J.3    Sickles, D.W.4
  • 62
    • 0018069550 scopus 로고
    • Inhibition of fast axoplasmic transport by acrylamide
    • Weir R. L., Glaubiger G., Chase T. N. Inhibition of fast axoplasmic transport by acrylamide. Environ. Res. 17:1978;251-255.
    • (1978) Environ. Res. , vol.17 , pp. 251-255
    • Weir, R.L.1    Glaubiger, G.2    Chase, T.N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.