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Volumn 266, Issue 1, 1999, Pages 260-273

RNA hairpin loops repress protein synthesis more strongly than hammerhead ribozymes

Author keywords

Hammerhead ribozyme; Loop induced degradation of mRNA; RNA hairpin loop; Self cleaving mRNA; Translational attentuation

Indexed keywords

BETA GALACTOSIDASE; RIBOZYME;

EID: 0033571083     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1999.00864.x     Document Type: Article
Times cited : (9)

References (50)
  • 2
    • 0031979354 scopus 로고    scopus 로고
    • Antisense inhibition of gene expression in bacteria by PNA targeted to mRNA
    • 2. Good, L. & Nielsen, P.E. (1998) Antisense inhibition of gene expression in bacteria by PNA targeted to mRNA. Nature Biotechnol. 16, 355-358.
    • (1998) Nature Biotechnol. , vol.16 , pp. 355-358
    • Good, L.1    Nielsen, P.E.2
  • 3
    • 0021760395 scopus 로고
    • The influence of messenger RNA secondary structure on expression of an immunoglobulin heavy chain in E. coli
    • 3. Wood, C.R., Boss, M.A., Patel, T.P. & Emtage, J.S. (1984) The influence of messenger RNA secondary structure on expression of an immunoglobulin heavy chain in E. coli. Nucleic Acids Res. 12, 3936-3949.
    • (1984) Nucleic Acids Res. , vol.12 , pp. 3936-3949
    • Wood, C.R.1    Boss, M.A.2    Patel, T.P.3    Emtage, J.S.4
  • 4
    • 0027417253 scopus 로고
    • Inhibition of translational initiation in the yeast S. cerevisiae as a function of the stability and position of hairpin structures in the mRNA leader
    • 4. Vega Laso, M.R., Zhu, D., Sagliocco, F., Brown, A.J.P., Tuite, M.F. & McCarthy, J.E. (1993) Inhibition of translational initiation in the yeast S. cerevisiae as a function of the stability and position of hairpin structures in the mRNA leader. J. Biol. Chem. 268, 6453-6462.
    • (1993) J. Biol. Chem. , vol.268 , pp. 6453-6462
    • Vega Laso, M.R.1    Zhu, D.2    Sagliocco, F.3    Brown, A.J.P.4    Tuite, M.F.5    McCarthy, J.E.6
  • 6
    • 0023221419 scopus 로고
    • A small catalytic oligoribonucleotide
    • 6. Uhlenbeck, O.C. (1987) A small catalytic oligoribonucleotide. Nature 328, 596-600.
    • (1987) Nature , vol.328 , pp. 596-600
    • Uhlenbeck, O.C.1
  • 7
    • 0024291288 scopus 로고
    • Simple RNA enzymes with new and highly specific endoribonuclease activities
    • 7. Haseloff, J. & Gerlach, W.L. (1988) Simple RNA enzymes with new and highly specific endoribonuclease activities. Nature 334, 585-591.
    • (1988) Nature , vol.334 , pp. 585-591
    • Haseloff, J.1    Gerlach, W.L.2
  • 9
    • 0031828144 scopus 로고    scopus 로고
    • Hammerhead ribozyme kinetics
    • 9. Stage-Zimmermann, T.K. & Uhlenbeck, O.C. (1998) Hammerhead ribozyme kinetics. RNA 4, 875-889.
    • (1998) RNA , vol.4 , pp. 875-889
    • Stage-Zimmermann, T.K.1    Uhlenbeck, O.C.2
  • 11
    • 0031945994 scopus 로고    scopus 로고
    • Specific RNA self-cleavage in coconut cadang cadang viroid: Potential for a role in rolling circle replication
    • 11. Liu, Y.-H. & Symons, R.H. (1998) Specific RNA self-cleavage in coconut cadang cadang viroid: potential for a role in rolling circle replication. RNA 4, 418-429.
    • (1998) RNA , vol.4 , pp. 418-429
    • Liu, Y.-H.1    Symons, R.H.2
  • 12
    • 0030803639 scopus 로고    scopus 로고
    • Progress toward the structure and therapeutic use of the hairpin ribozyme
    • 12. Earnshaw, D.J. & Gait, M.J. (1997) Progress toward the structure and therapeutic use of the hairpin ribozyme. Antisense Nucleic Acid Drug Dev. 7, 403-411.
    • (1997) Antisense Nucleic Acid Drug Dev. , vol.7 , pp. 403-411
    • Earnshaw, D.J.1    Gait, M.J.2
  • 13
    • 0002754552 scopus 로고    scopus 로고
    • Group I ribozymes: Substrate recognition, catalytic strategies, and comparative mechanistic analysis
    • 13. Cech, T.R. & Herschlag, D. (1996) Group I ribozymes: substrate recognition, catalytic strategies, and comparative mechanistic analysis. Catalytic RNA, Nucleic Acids Mol. Biol. 10, 1-17.
    • (1996) Catalytic RNA, Nucleic Acids Mol. Biol. , vol.10 , pp. 1-17
    • Cech, T.R.1    Herschlag, D.2
  • 14
    • 0000751372 scopus 로고    scopus 로고
    • Structural analysis of the bacterial ribonuclease P RNA
    • 14. Nolan, J.M. & Pace, N.R. (1996) Structural analysis of the bacterial ribonuclease P RNA. Catalytic RNA, Nucleic Acids Mol. Biol. 10, 109-128.
    • (1996) Catalytic RNA, Nucleic Acids Mol. Biol. , vol.10 , pp. 109-128
    • Nolan, J.M.1    Pace, N.R.2
  • 15
    • 0006389316 scopus 로고    scopus 로고
    • Crystal violet can be used to visualize DNA bands during gel electrophoresis and to improve cloning efficiency
    • 15. Rand, K.N. (1996) Crystal violet can be used to visualize DNA bands during gel electrophoresis and to improve cloning efficiency. Trends Pharmacol. Sci. T40022-1.
    • (1996) Trends Pharmacol. Sci.
    • Rand, K.N.1
  • 16
    • 0023682126 scopus 로고
    • Hyper-regulation of pyr gene expression in E. coli cells with slow ribosomes
    • 16. Jensen, K.P. (1988) Hyper-regulation of pyr gene expression in E. coli cells with slow ribosomes. Eur. J. Biochem. 175, 587-593.
    • (1988) Eur. J. Biochem. , vol.175 , pp. 587-593
    • Jensen, K.P.1
  • 17
    • 49849113253 scopus 로고
    • A simple method for extraction of RNA from E. coli utilizing diethylpyrocarbonate
    • 17. Summers, W.C. (1970) A simple method for extraction of RNA from E. coli utilizing diethylpyrocarbonate. Anal. Biochem. 33, 459-463.
    • (1970) Anal. Biochem. , vol.33 , pp. 459-463
    • Summers, W.C.1
  • 19
    • 0023277545 scopus 로고
    • Single-step method of isolation by acid guanidiniumthiocyanate-phenol-chloroform extraction
    • 19. Chomczynski, P. & Sacchi, N. (1987) Single-step method of isolation by acid guanidiniumthiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 20
    • 0024357988 scopus 로고
    • Specific gene suppression by engineered ribozymes inmonkey cells
    • 20. Cameron, F.H. & Jennings, P.A. (1989) Specific gene suppression by engineered ribozymes inmonkey cells. Proc. Natl Acad. Sci. USA 86, 9139-9143.
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , pp. 9139-9143
    • Cameron, F.H.1    Jennings, P.A.2
  • 21
    • 0026562551 scopus 로고
    • Expression of a chimeric ribozyme gene results in endonucleolytic cleavage of target RNA and a comcomitant reduction of gene expression in vivo
    • 21. Steinecke, P., Herget, T. & Schreier, P.H. (1992) Expression of a chimeric ribozyme gene results in endonucleolytic cleavage of target RNA and a comcomitant reduction of gene expression in vivo. EMBO J. 11, 1525-1530.
    • (1992) EMBO J. , vol.11 , pp. 1525-1530
    • Steinecke, P.1    Herget, T.2    Schreier, P.H.3
  • 23
    • 0024367068 scopus 로고
    • Can ribozymes be used to regulate prokaryote gene expression?
    • 23. Chuat, J.-C. & Galibert, F. (1989) Can ribozymes be used to regulate prokaryote gene expression? Biochem. Biophys. Res. Commun. 162, 1025-1029.
    • (1989) Biochem. Biophys. Res. Commun. , vol.162 , pp. 1025-1029
    • Chuat, J.-C.1    Galibert, F.2
  • 24
    • 0025864336 scopus 로고
    • Prevention of human immunodeficiency virus type 1 integrase expression in E. coli by a ribozyme
    • 24. Sioud, M. & Drlica, K. (1991) Prevention of human immunodeficiency virus type 1 integrase expression in E. coli by a ribozyme. Proc. Natl Acad. Sci. USA 88, 7303-7307.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 7303-7307
    • Sioud, M.1    Drlica, K.2
  • 25
    • 0028878615 scopus 로고
    • Tight transcriptional control mechanism ensuresstable high-level expression from T7 promoter-based expression plasmids
    • 25. Mertens, N., Remaut, E. & Fiers, W. (1995) Tight transcriptional control mechanism ensuresstable high-level expression from T7 promoter-based expression plasmids. Biotechnology 13, 175-179.
    • (1995) Biotechnology , vol.13 , pp. 175-179
    • Mertens, N.1    Remaut, E.2    Fiers, W.3
  • 26
    • 0031574065 scopus 로고    scopus 로고
    • The effect of structure in a long target RNA on ribozyme cleavage efficiency
    • 26. Campbell, T.B., McDonald, C.K. & Hagen, M. (1997) The effect of structure in a long target RNA on ribozyme cleavage efficiency. Nucleic Acids Res. 25, 4985-4993.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 4985-4993
    • Campbell, T.B.1    McDonald, C.K.2    Hagen, M.3
  • 27
    • 0032486203 scopus 로고    scopus 로고
    • Ribozyme-mediated repair of sickle β-globin mRNAs in erythrocyte precursors
    • 27. Lan, N., Howrey, R.P., Lee, S.-W., Smith, C.A. & Sullenger, B.A. (1998) Ribozyme-mediated repair of sickle β-globin mRNAs in erythrocyte precursors. Science 280, 1593-1596.
    • (1998) Science , vol.280 , pp. 1593-1596
    • Lan, N.1    Howrey, R.P.2    Lee, S.-W.3    Smith, C.A.4    Sullenger, B.A.5
  • 28
    • 0022435128 scopus 로고
    • SV40 enhancer activation during retinoic acid-induced differentiation of F9 embryonal carcinoma cells
    • 28. Sleigh, M.J. & Lockett, T.J. (1985) SV40 enhancer activation during retinoic acid-induced differentiation of F9 embryonal carcinoma cells. EMBO J. 4, 3831-3837.
    • (1985) EMBO J. , vol.4 , pp. 3831-3837
    • Sleigh, M.J.1    Lockett, T.J.2
  • 30
    • 0030629909 scopus 로고    scopus 로고
    • Minimized hammerhead ribozymes
    • Turner, P.C., ed. Humana Press, Princeton, NJ
    • 30. McCall, M.J., Hendry, P. & Lockett, T.J. (1996) Minimized hammerhead ribozymes. Methods in Molecular Biology (Turner, P.C., ed.), Vol. 74, pp. 151-159. Humana Press, Princeton, NJ.
    • (1996) Methods in Molecular Biology , vol.74 , pp. 151-159
    • McCall, M.J.1    Hendry, P.2    Lockett, T.J.3
  • 31
    • 0029586990 scopus 로고
    • Efficient hammerhead ribozymemediated cleavage of the structured hepatitis B virus encapsidation signal in vitro and in cell extracts but not in intact cells
    • 31. Beck, J. & Nassal, M. (1995) Efficient hammerhead ribozymemediated cleavage of the structured hepatitis B virus encapsidation signal in vitro and in cell extracts but not in intact cells. Nucleic Acids Res. 23, 4954-4962.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 4954-4962
    • Beck, J.1    Nassal, M.2
  • 32
    • 0029815359 scopus 로고    scopus 로고
    • A hammerhead ribozyme cleaves its target RNA during RNA preparation
    • 32. Heidenreich, O., Xu, X. & Nerenberg, M. (1996) A hammerhead ribozyme cleaves its target RNA during RNA preparation. Antisense Nucl Acid Drug Dev. 6, 141-144.
    • (1996) Antisense Nucl Acid Drug Dev. , vol.6 , pp. 141-144
    • Heidenreich, O.1    Xu, X.2    Nerenberg, M.3
  • 33
    • 0028859512 scopus 로고
    • A comparison of the in vitro activity of DNA-armed and all-RNA hammerhead ribozymes
    • 33. Hendry, P. & McCall, M.J. (1995) A comparison of the in vitro activity of DNA-armed and all-RNA hammerhead ribozymes. Nucleic Acids Res. 23, 3928-3936.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 3928-3936
    • Hendry, P.1    McCall, M.J.2
  • 34
    • 0025998488 scopus 로고
    • Role of divalent metal ions in hammerhead RNA cleavage reaction
    • 34. Dahm, S.C. & Uhlenbeck, O.C. (1991) Role of divalent metal ions in hammerhead RNA cleavage reaction. Biochemistry 30, 9464-9469.
    • (1991) Biochemistry , vol.30 , pp. 9464-9469
    • Dahm, S.C.1    Uhlenbeck, O.C.2
  • 35
    • 0032146201 scopus 로고    scopus 로고
    • Intracellular RNA cleavage by the hairpin ribozyme
    • 35. Seyhan, A.A., Amaral, J. & Burke, J.M. (1998) Intracellular RNA cleavage by the hairpin ribozyme. Nucleic Acids Res. 26, 3494-3504.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 3494-3504
    • Seyhan, A.A.1    Amaral, J.2    Burke, J.M.3
  • 36
    • 0021724702 scopus 로고
    • Structural specificities of five commonly-used nucleases
    • 36. Drew, H.R. (1984) Structural specificities of five commonly-used nucleases. J. Mol. Biol. 176, 535-557.
    • (1984) J. Mol. Biol. , vol.176 , pp. 535-557
    • Drew, H.R.1
  • 37
    • 0029941783 scopus 로고    scopus 로고
    • Cloning and characterization of extended hammerheads from a diverse set of caudate amphibians
    • 37. Zhang, Y. & Epstein, L.M. (1996) Cloning and characterization of extended hammerheads from a diverse set of caudate amphibians. Gene 172, 183-190.
    • (1996) Gene , vol.172 , pp. 183-190
    • Zhang, Y.1    Epstein, L.M.2
  • 38
    • 0030956463 scopus 로고    scopus 로고
    • Efficient hammerhead ribozyme and antisense RNA targeting in a slow ribosome E. coli mutant
    • 38. Chen, H., Ferbeyre, G. & Cedergren, R. (1997) Efficient hammerhead ribozyme and antisense RNA targeting in a slow ribosome E. coli mutant. Nat. Biotechnol. 15, 432-435.
    • (1997) Nat. Biotechnol. , vol.15 , pp. 432-435
    • Chen, H.1    Ferbeyre, G.2    Cedergren, R.3
  • 39
    • 0031592947 scopus 로고    scopus 로고
    • Streptomycin binds to the decoding center of 16S ribosomal RNA
    • 39. Spickler, C., Brunelle, M.-N. & Brakier-Gingras, L. (1997) Streptomycin binds to the decoding center of 16S ribosomal RNA. J. Mol. Biol. 273, 586-599.
    • (1997) J. Mol. Biol. , vol.273 , pp. 586-599
    • Spickler, C.1    Brunelle, M.-N.2    Brakier-Gingras, L.3
  • 40
    • 0030712114 scopus 로고    scopus 로고
    • The efficiency of a cis-cleaving ribozyme in an mRNA coding region is influenced by the translating ribosome in vivo
    • 40. Zhang, S., Stancek, M. & Isaksson, L.A. (1997) The efficiency of a cis-cleaving ribozyme in an mRNA coding region is influenced by the translating ribosome in vivo. Nucleic Acids Res. 25, 4301-4306.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 4301-4306
    • Zhang, S.1    Stancek, M.2    Isaksson, L.A.3
  • 43
    • 0028224199 scopus 로고
    • High-resolution molecular discrimination by RNA
    • 43. Jenison, R.D., Gill, S.C., Pardi, A. & Polisky, B. (1994). High-resolution molecular discrimination by RNA. Science 263, 1425-1429.
    • (1994) Science , vol.263 , pp. 1425-1429
    • Jenison, R.D.1    Gill, S.C.2    Pardi, A.3    Polisky, B.4
  • 44
    • 0032576953 scopus 로고    scopus 로고
    • Reduction of Cripto-1 expression by a hammerhead-shaped RNA molecule results from inhibition of translation rather than mRNA cleavage
    • 44. Kintner, R.L. & Hosick, H.L. (1998) Reduction of Cripto-1 expression by a hammerhead-shaped RNA molecule results from inhibition of translation rather than mRNA cleavage. Biochem. Biophys. Res. Commun. 245, 774-779.
    • (1998) Biochem. Biophys. Res. Commun. , vol.245 , pp. 774-779
    • Kintner, R.L.1    Hosick, H.L.2
  • 45
    • 0029896908 scopus 로고    scopus 로고
    • Detection of hammerhead ribozyme-mediated cleavage and reduced expression of LacZ mRNA in E. coli
    • 45. Junn, E. & Kang, C. (1996) Detection of hammerhead ribozyme-mediated cleavage and reduced expression of LacZ mRNA in E. coli. Genetic Anal. Biomol. Eng. 13, 1-7.
    • (1996) Genetic Anal. Biomol. Eng. , vol.13 , pp. 1-7
    • Junn, E.1    Kang, C.2
  • 46
    • 0031935854 scopus 로고    scopus 로고
    • Structural similarities between hammerhead ribozymes and the spliceosomal RNAs could be responsible for lack of ribozyme cleavage in yeast
    • 46. Castanotto, D., Li, H., Chow, W., Rossi, J.J. & Deshler, J.O. (1998) Structural similarities between hammerhead ribozymes and the spliceosomal RNAs could be responsible for lack of ribozyme cleavage in yeast. Antisense Nucleic Acid Drug Dev. 8, 1-13.
    • (1998) Antisense Nucleic Acid Drug Dev. , vol.8 , pp. 1-13
    • Castanotto, D.1    Li, H.2    Chow, W.3    Rossi, J.J.4    Deshler, J.O.5
  • 47
    • 0033551137 scopus 로고    scopus 로고
    • Oligoribonuclease is an essential component of the mRNA decay pathway
    • 47. Ghosh, S. & Deutscher, M.P. (1999) Oligoribonuclease is an essential component of the mRNA decay pathway. Proc. Natl Acad. Sci. USA 96, 4372-4377.
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 4372-4377
    • Ghosh, S.1    Deutscher, M.P.2
  • 48
    • 0028288686 scopus 로고
    • A kinetic and thermodynamic framework for the hammerhead ribozyme reaction
    • 48. Hertel, K.J., Herschlag, D. & Uhlenbeck, O.G. (1994) A kinetic and thermodynamic framework for the hammerhead ribozyme reaction. Biochemistry 33, 3374-3385.
    • (1994) Biochemistry , vol.33 , pp. 3374-3385
    • Hertel, K.J.1    Herschlag, D.2    Uhlenbeck, O.G.3
  • 50
    • 0142102891 scopus 로고    scopus 로고
    • Transsplicing ribozymes for targeted gene delivery
    • 50. Kohler, U., Ayre, B.G., Goodman, H.M. & Haseloff, J. (1999) Transsplicing ribozymes for targeted gene delivery. J. Mol. Biol. 285, 1935-1950.
    • (1999) J. Mol. Biol. , vol.285 , pp. 1935-1950
    • Kohler, U.1    Ayre, B.G.2    Goodman, H.M.3    Haseloff, J.4


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