Conjugation of polyethylene glycol via a disulfide bond confers water solubility upon a peptide model of a protein transmembrane segment

Analytical Biochemistry

Volumn 275, Issue 2, 1999, Pages 224-230

  Pomroy, Neil C ^a   Deber, Charles M ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; ALIPHATIC COMPOUNDS; COVALENT BONDS; HYDROPHOBICITY; PEPTIDES; POLYETHYLENES; REAGENTS; SOLUBILITY; SULFUR COMPOUNDS;

DISULFIDE BONDS; FUSION PROTEINS; HYDROPHOBIC PEPTIDES; MEMBRANE PROTEINS; STRUCTURAL CHARACTERIZATION; TRANS-MEMBRANE DOMAINS; TRANSMEMBRANE SEGMENTS; WATER SOLUBILITIES;

POLYETHYLENE GLYCOLS;

CYSTEINE; DISULFIDE; MACROGOL; WATER;

ARTICLE; CONJUGATION; HYDROPHOBICITY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN PURIFICATION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; REACTION ANALYSIS; SOLUBILITY;

EID: 0033571026     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1006/abio.1999.4315     Document Type: Article

References (27)

1. Garavito R. M., Picot D., Loll P. J. J. Bioenerg. Biomembr. 28:1996;13-27.
2. Clore G. M., Gronenborn A. M. Trends Biotechnol. 16:1998;22-34.
3. Peng S., Liu L. P., Emili A. Q., Deber C. M. FEBS Lett. 431:1998;29-33.
4. Henry G. D., Sykes B. D. Methods Enzymol. 239:1994;515-535.
5. Abuchowski A., van Es T., Palczuk N. C., Davis F. F. J. Biol. Chem. 252:1977;3578-3581.
6. Delgado C., Francis G. E., Fisher D. Crit. Rev. Ther. Drug Carrier Syst. 9:1992;249-304.
7. Sirokman G., Fasman G. D. Protein Sci. 2:1993;1161-1170.
8. Wei J., Fasman G. D. Biochemistry. 34:1995;6408-6415.
9. Felix, A. M. 1997, in, Poly(ethylene glycol): Chemistry and Biological Applications, (, Harris, J. M, and Zalipsky, S, Eds.), Am. Chem. Soc, Washington, DC.
10. Pomroy N. C., Deber C. M. Biochem. Biophys. Res. Commun. 245:1998;618-621.
11. Ladd D. L., Snow R. A. Anal. Biochem. 210:1993;258-263.
12. Walmsley T. A., Abernethy M. H., Fitzgerald H. P. Clin. Chem. 33:1987;1928-1931.
13. Skoog B. Vox Sang. 37:1979;345-349.
14. TM User Manual, (Application File No. 300), Pharmacia Biotech, Sweden.
15. Kurfurst M. M. Anal. Biochem. 200:1992;244-248.
16. Ellman G. L. Arch. Biochem. Biophys. 82:1959;70.
17. Akabas M. H., Cheung M., Guinamard R. J. Bioenerg. Biomembr. 29:1997;453-463.
18. Zalipsky S., Lee C. Harris J. M. Poly(ethylene glycol) Chemistry: Biotechnical and Biomedical Applications. 1992;Plenum Press, New York.
19. Morpurgo M., Veronese F. M., Kachensky D., Harris J. M. Bioconjug. Chem. 7:1996;363-368.
20. Musu T., Azarkan M., Brygier J., Paul C., Vincentelli J., Baeyens-Volant D., Guermant C., Nijs M., Looze Y. App. Biochem. Biotechnol. 56:1996;243-263.
21. Campbell R. M., Heimer E. P., Ahmad M., Eisenbeis H. G., Lombros T. J., Lee Y., Miller R. W., Stricker P. R., Felix A. M. J. Pept. Res. 49:1997;527-537.
22. Flory P. J. J. Am. Chem. Soc. 62:1940;1561.
23. Liu L.-P., Li S.-C., Goto N. K., Deber C. M. Biopolymers. 39:1996;465-470.
24. Folk J. E., Piez K. A., Carroll W. R., Gladner J. A. J. Biol. Chem. 235:1960;2272-2277.
25. Kyte J., Doolittle R. F. J. Mol. Biol. 157:1982;105-132.
26. Stuber W., Koschinsky R., Reers M., Hoffmann D., Czech J., Dickneite G. Pept. Res. 8:1995;78-85.
27. Arnold F. H. FASEB J. 7:1993;744-749.