Genome screen for platelet monoamine oxidase (MAO) activity

American Journal of Medical Genetics - Neuropsychiatric Genetics

Volumn 88, Issue 5, 1999, Pages 517-521

  Saccone, Nancy L ^a   Rice, John P ^a   Rochberg, Nan ^a   Goate, Alison ^a   Reich, Theodore ^a   Shears, Shantia ^a   Wu, William ^a   Nurnberger Jr , John I ^b   Foroud, Tatiana ^b   Edenberg, Howard J ^b   Li, Ting Kai ^b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INDIANA UNIVERSITY   (United States)

Author keywords

Linkage; MAO activity; Quantitative trait; Sib pair analysis

Indexed keywords

ARTICLE; ENZYME ACTIVITY; ENZYME ASSAY; FEMALE; GENETIC ANALYSIS; GENETIC LINKAGE; GENETIC SCREENING; GENOTYPE; HUMAN; HUMAN EXPERIMENT; MALE; MARKER GENE; PRIORITY JOURNAL; QUANTITATIVE TRAIT; SIBLING;

BLOOD PLATELETS; CHROMOSOMES, HUMAN, PAIR 2; CHROMOSOMES, HUMAN, PAIR 6; FAMILY; FEMALE; GENETIC MARKERS; GENETIC SCREENING; GENOTYPE; HUMANS; LINKAGE (GENETICS); LOD SCORE; MALE; MONOAMINE OXIDASE; SMOKING;

EID: 0033569937     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/(SICI)1096-8628(19991015)88:5<517::AID-AJMG15>3.0.CO;2-B     Document Type: Article

References (43)

1. Anthenelli RM, Tipp J, Li T-K, Magnes L, Schuckit MA, Rice J, Daw EW, Nurnberger Jr JI. 1998. Platelet monoamine oxidase (MAO) activity in subgroups of alcoholics and controls: results from the Collaborative Study on the Genetics of Alcoholism. Alcohol Clin Exp Res 22:598-604.
2. Bach AWJ, Lan NC, Johnson DL, Abell CW, Bembenek ME, Kwan S-W, Seeburg PH, Shih JC. 1988. cDNA cloning of human liver monoamine oxidase A and B: molecular basis of differences in enzymatic properties. Proc Natl Acad Sci USA 85:4934-4938.
3. Bench CJ, Price GW, Lammertsma AA, Cramer JC, Luthra SK, Turton D, Dolan RJ, Kettler R, Dingemanse J, DaPrada M, Biziere K, McClelland GR, Jamieson VL, Wood ND, Frackowiak RSJ. 1991. Measurement of human cerebral monoamine oxidase type B (MAO-B) activity with positron emission tomography (PET): a dose ranging study with the reversible inhibitor Ro 19-6327.Europ J Clin Pharmacol 40:169-173.
4. Boehnke M. 1991. Allele frequency estimation from pedigree data. Amer J Hum Genet 48:22-25.
5. Cloninger CR, von Knorring L, Oreland L. 1985. Pentametric distribution of platelet monoamine oxidase activity. Psychiatry Res 15:133-143.
6. Corash L. 1980. Platelet heterogeneity: relevance to the use of platelets to study psychiatric disorders. Schizophr Bull 1980; 6:254-258.
7. Dolinsky ZS, Shaskan EG, Hesselbrock MN. 1985. Basic aspects of blood platelet monoamine oxidase activity in hospitalized men alcoholics. J Studies on Alcohol 46:81-85.
8. Elston RC, Stewart J. 1971. A general method for the genetic analysis of pedigree data. Hum Hered 21:523-542.
9. Farren CK, Clare AW, Tipton KJ, Dinan TG. 1998. Platelet MAO activity in subtypes of alcoholics and controls in a homogeneous population. J Psychiatric Res 32:49-54.
10. Fowler CJ, Tipton KF, MacKay AVP, Youdim MBH. 1982. Human platelet monoamine oxidase: a useful enzyme in the study of psychiatric disorders? Neuroscience 7:1577-1594.
11. Fowler JS, Volkow ND, Wang G-J, Pappas N, Logan J, MacGregor R, Alexoff D, Shea C, Schlyer D, Wolf AP, Warner D, Zezulkova I, Cilento R. 1996. Inhibition of monoamine oxidase B in the brains of smokers. Nature 379:733-736.
12. Goldin LR, Gershon ES, Lake CR, Murphy DL, McGinniss M, Sparkes RS. 1982. Segregation and linkage studies of plasma dopamine-betahydroxylase (DBH), erythrocyte catechol-O-methyltransferase (COMT) and platelet monoamine oxidase (MAO): possible linkage between the ABO locus and a gene controlling DBH activity. Am J Hum Genet 34:250-262.
13. Lander ES, Green P. 1987. Construction of multilocus genetic linkage maps in humans. Proc. Natl. Acad. Sci. USA 84:2363-2367.
14. Haseman JK, Elston RC. 1972. The investigation of linkage between a quantitative trait and a marker locus. Behav. Genet. 2:3-19.
15. Hauser ER, Boehnke M, Guo S-W, Risch N. 1996. Affected-sib-pair interval mapping and exclusion for complex genetic traits: sampling considerations. Genet Epidemiol 13:117-137.
16. Hsu Y-PP, Powell JF, Sims KB, Breakefield XO. 1989. Molecular genetics of the monoamine oxidases. J. Neurochem 53:12-18.
17. Hussein L, Sindarto E, Goedde HW. 1980. Twin studies and substrate differences in platelet monoamine oxidase activity. Hum Hered 30:65-70.
18. Kruglyak L and Lander ES. 1995. Complete multipoint sib-pair analysis of qualitative and quantitative traits. Am J Hum Genet 57:439-454.
19. Lalouel, JM, Morton NE. 1981. Complex segregation analysis with pointers. Hum Hered 31:312-321.
20. Leckman JF, Gershon ES, Nichols AS, Murphy DL. 1977. Reduced MAO activity in first-degree relatives of individuals with bipolar affective disorders. Arch Gen Psychiatry 34:601-606.
21. Major LF, Murphy DL. 1978. Platelet and plasma amine oxidase activity in alcoholic individuals. Brit J Psychiatry 132:548-554.
22. Mantle TJ, Tipton KF, Garrett NJ. 1976. Inhibition of monoamine oxidase by amphetamine and related compounds. Biochem Pharmacol 25: 2073-2077.
23. Marcolin MA, Davis JM. 1992. Platelet monoamine oxidase in schizophrenia: a meta-analysis. Schizophrenia Res 7:249-267.
24. Morton NE, MacLean CJ. 1974. Analysis of family resemblance. III. Complex segregation of quantitative traits. Am J Hum Genet 26:489-503.
25. Murphy DL, Weiss R. 1972. Reduced monoamine oxidase activity in blood platelets from bipolar depressed patients. Am J Psychiatry 128:1351-1357.
26. Murphy DL, Wyatt RJ. 1972. Reduced platelet monoamine oxidase activity in blood platelets from schizophrenic patients. Nature 238:225-226.
27. Murray JC, Buetow KH, Weber JL, Ludwigsen S, Scherpbier-Heddema T, Manion F, Quillen J, Sheffield VC, Sunden S, Duyk GM, Weissenbach J, Gyapay G, Dib C, Morrissette J, Lathrop GM, Vignal A, White R, Matsunami N, Gerken S, Melis R, Albertsen H, Plaetke R, Odelberg S, Ward D, Dausset J, Cohen D, Cann H. 1994. A comprehensive human linkage map with centimorgan density. Science 265:2049-2054.
28. Nies A, Robinson DS, Lamborn KR, Lampert RP. 1973. Genetic control of platelet and plasma monoamine oxidase activity. Arch Gen Psychiatry 28:834-838.
29. Norman TR, Chamberlain KG, French MA, Burrows GD. 1982. Platelet monoamine oxidase activity and cigarette smoking. J Affective Disorders 4:73-77.
30. Oreland L, Fowler CJ, Schalling D. 1981. Low platelet monoamine oxidase activity in cigarette smokers. Life Sci 29:2511-2518.
31. Pandey GN, Dorus E, Shaughnessy R, Davis JM. 1979. Genetic control of platelet monoamine oxidase activity: studies on normal families. Life Sci 25:1173-1178.
32. Parsian A, Suarez BK, Tabakoff B, Hoffman P, Ovchinnikova L, Fisher L, Cloninger CR. 1995. Monoamine oxidases and alcoholism. I. Studies in unrelated alcoholics and normal controls. Am J Med Genet (Neuropsychiatr Genet) 60:409-416.
33. Reich T, Edenberg HJ, Goate A, Williams JT, Rice JP, Van Eerdewegh P, Foroud T, Hesselbrock V, Schuckit MA, Bucholz K, Porjesz B, Li T-K, Conneally PM, Nurnberger Jr. JI, Tischfield JA, Crowe R, Cloninger CR, Wu W, Shears S, Carr K, Crose C, Willig C, Begleiter H. 1998. A genome-wide search for genes affecting the risk for alcohol dependence. Am J Med Genet (Neuropsychiatr Genet) 81:207-215.
34. Rice J, McGuffin P, Shaskan EG. 1982. A commingling analysis of platelet monoamine oxidase activity. Psychiatry Res 7:325-335.
35. Rice J, McGuffin P, Boldin LR, Shaskan EG, Gershon ES. 1984. Platelet monoamine oxidase (MAO) activity: Evidence for a single major locus. Am J Hum Genet 36:36-43.
36. Stillman RC, Wyatt RJ, Murphy DL, Rauscher FP. 1978. Low platelet monoamine oxidase activity and chronic marijuana use. Life Sci 23: 1577-1582.
37. Suarez BK, Hampe CL, Parsian A, Cloninger CR. 1995. Monoamine oxidases and alcoholism. II. Studies in alcoholic families. Am J Med Genet (Neuropsychiatr Genet) 60:417-423.
38. Sullivan JL, Cavenar JO Jr, Maltbie AA, Lister P, Zung WWK. 1979. Familial biochemical and clinical correlates of alcoholics with low platelet monoamine oxidase activity. Biol Psychiatry 14:385-394.
39. von Knorring A, Hallman J, Knorring L von, Oreland L. 1991. Platelet monoamine oxidase activity in type I and type 2 alcoholism. Alcohol Alcoholism 26:409-416.
40. Winter H, Herschel M, Propping P, Friedl W, Vogel F. 1978. A twin study on three enzymes (DBH, COMT, MAO) of catecholamine metabolism. Correlations with MMPI. Psychopharmacology 57:63-69.
41. Wurtman RJ, Axelrod J. 1963. A sensitive and specific assay for the estimation of monoamine oxidase. Biochem Pharmacol 1439-1440.
42. Wyatt RJ, Potkin SG, Bridge TP, Phelps BH, Wise CD. 1980. Monoamine oxidase in schizophrenia: an overview. Schizophrenia Bull 6:199-207.
43. Zureick JL and Meltzer HY. 1988. Platelet MAO activity in hallucinating and paranoid schizophrenics: a review and meta-analysis. Biol Psychiatry 24:63-78.