Fibrin fragment induction of plasminogen activator inhibitor transcription is mediated by activator protein-1 through a highly conserved element

Blood

Volumn 94, Issue 6, 1999, Pages 2029-2038

  Olman, Mitchell A ^a   Hagood, James S ^b   Simmons, Warren L ^b   Fuller, Gerald M ^b   Vinson, Charles ^b   White, Kimberly E ^b  

^a University of Alabama at Birmingham Heersink School of Medicine   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

D DIMER; FIBRIN DEGRADATION PRODUCT; FIBRINOGEN; PLASMINOGEN ACTIVATOR INHIBITOR 1;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; DNA BINDING; FIBRINOLYSIS; GENE MUTATION; GENETIC TRANSCRIPTION; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; WOUND HEALING;

EID: 0033567905     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v94.6.2029.418k25_2029_2038     Document Type: Article

References (55)

1. Dvorak HF, Senger DR, Dvorak AM, Harvey VS, McDonagh J: Regulation of extravascular coagulation by microvascular permeability. Science 227:1059, 1985
2. Dvorak HF, Harvey VS, Estrella P, Brown LF, McDonagh J, Dvorak AM: Fibrin containing gels induce angiogenesis. Implications for tumor stroma generation and wound healing. Lab Invest 57:673, 1987
3. Brown LF, Dvorak AM, Dvorak HF: Leaky vessels, fibrin deposition, and fibrosis: a sequence of events common to solid tumors and to many other types of disease [review]. Am Rev Resp Dis 140:1104, 1989
4. Olman M, Mackman N, Gladson C, Moser K, Loskutoff D: Changes in procoagulant and fibrinolytic gene expression during bleomycin induced lung injury in the mouse. J Clin Invest 96:1621, 1995
5. Bugge TH, Kombrinck KW, Flick MJ, Daugherty CC, Danton MS, Degen JL: Loss of fibrinogen rescues mice from the pleiotropic effects of plasminogen deficiency. Cell 87:709, 1996
6. Smith EB, Thompson WD: Fibrin as a factor in atherogenesis. Thromb Res 73:1, 1995
7. Ny T, Sawdey M, Lawrence DA, Millan JL, Loskutoff DJ: Cloning and sequence of a cDNA coding for the human β-migrating endothelial-cell-type plasminogen activator inhibitor. Proc Natl Acad Sci USA 83:6776, 1986
8. van Mourik JA, Lawrence DA, Loskutoff DJ: Purification of an inhibitor of plasminogen activators (antiactivator) synthesized by endothelial cells. J Biol Chem 259:14914, 1984
9. Loskutoff DJ, Sawdey M, Mimuro J: Type I plasminogen activator inhibitor, in Coller B (ed): Progress in Hemostasis and Thrombosis. Columbia, MD, Bermedica Production, 1989, p 87
10. Loskutoff DJ, Schleef RR: Plasminogen activators and their inhibitors. Methods Enzymol 163:293, 1988
11. Flaumenhaft R, Abe M, Mignatti P, Rifkin DB: Basic fibroblast growth factor-induced activation of latent transforming growth factor β in endothelial cells: Regulation of plasminogen activator activity. J Cell Physiol 118:901, 1992
12. Kirchheimer JC, Binder BR, Remold HG: Matrix-bound plasminogen activator inhibitor type 1 inhibits the invasion of human monocytes into interstitial tissue. J Immunol 145:1518, 1990
13. Deng G, Curriden SA, Wang S, Rosenberg S, Loskutoff DJ: Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release. J Cell Biol 134:1563, 1996
14. Waltz DA, Natkin L, Fujita RM, Wei Y, Chapman HA: Plasmin and plasminogen activator inhibitor type 1 promote cellular motility by regulating the interaction between the urokinase receptor and vitronectin. J Clin Invest 100:58, 1997
15. Stefansson S, Lawrence DA: The serpin PAI-1 inhibits cell migration by blocking intergrin αVβ3 binding to vitronectin. Nature 383:441, 1996
16. Carmeliet P, Stassen JM, Schoonjans L, Ream B: Plasminogen activator inhibitor-1 gene-deficient mice. II. Effects on hemostasis, thrombosis, and thrombolysis. J Clin Invest 92:2756, 1993
17. Eitzman DT, McCoy RD, Zheng X, Fay WP, Shen T, Ginsburg D, Simon RH: Bleomycin-induced pulmonary fibrosis in transgenic mice that either lack or overexpress the murine plasminogen activator inhibitor-I gene. J Clin Invest 1:232, 1996
18. Greiling D, Clark RAF: Fibronectin provides a conduit for fibroblast transmigration from collagenous stroma into fibrin clot provisional matrix. J Cell Sci 110:861, 1997
19. Seebacher T, Manske M, Zoller J, Crab J, Bade EG: The EGF-inducible protein EIP-1 of migrating normal and malignant rat liver epithelial cells in identical to plasminogen activator inhibitor 1 and is a component of the ECM migration tracks. Exp Cell Res 203:504, 1992
20. Crutchley DJ, Conanan LB, Maynard JR: Human fibroblasts produce inhibitor directed against plasminogen activator when treated with glucocorticoids. Ann NY Acad Sci 370:609, 1981
21. Laiho M, Saksela O, Andreasen PA, Keski-Oja J: Enhanced production and extracellular deposition of the endothelial-type plasminogen activator inhibitor in cultured human lung fibroblasts by transforming growth factor-β. J Cell Physiol 103:2403, 1986
22. Lund LR, Riccio A, Andreasen PA, Nielsen LS, Kristensen P, Laiho M, Saksela O, Blasi F, Dano K: Transforming growth factor-β is a strong and fast acting positive regulator of the level of type-1 plasminogen activator inhibitor mRNA in WI-38 human lung fibroblasts. EMBO J 6:1281, 1987
23. Circolo A, Welgus HG, Pierce GF, Kramer J, Strunk RC: Differential regulation of the expression of proteinases/antiproteinases in fibroblasts. J Biol Chem 266:12283, 1991
24. ldell S, Zwieb C, Boggaram J, Holiday D, Johnson AR: Mechanisms of fibrin formation and lysis by human lung fibroblasts influence of TGF-beta and TNF-alpha. Am J Physiol 263:L487, 1992
25. Samad F, Bergtrom G, Amrani DL: Regulation of plasminogen activation by interleukin-6 in human lung fibroblasts. Biochimica Biophys Acta 1221:307, 1994
26. Olman MA, Simmons WL, Pollman DJ, Loftis AY, Bini A, Miller EJ, Fuller GM, Rivera K: Polymerization of fibrinogen in murine bleomycin-induced lung injury. Am J Physiol 271:L519, 1996
27. Hagood JS, Olman MA, Zeballos JG, Rivera KE, Fuller GM: Regulation of type I plasminogen activator inhibitor by fibrin degradation products in rat lung fibroblasts. Blood 87:3749, 1996
28. Bruzdzinski CJ, Riordan-Johnson M, Nordby EC, Suter SM, Gelehrter TD: Isolation and characterization of the rat plasminogen activator inhibitor-1 gene. J Biol Chem 265:2078, 1990
29. Johnson MR, Bruzdzinski CJ, Winograd SS, Gelehrter TD: Regulatory sequences and protein-binding sites involved in the expression of the rat plasminogen activator inhibitor-1 gene. J Biol Chem 267:12202, 1992
30. Olive M, Krylov D, Echlin DR, Gardner K, Taparowsky E, Vinson C: A dominant negative to activation protein-1 (AP1) that abolishes DNA binding and inhibits oncogenesis. J Biol Chem 272: 18586, 1997
31. Olman MA, Williams WF, Strickland JH, Hagood JS, Simmons WL, Rivera KE: Facile purification of fibrin(ogen) fragments using a computer based model with general applicability to the generation of salt gradients. Prot Exp Purif 14:71, 1998
32. Gailit J, Clarke C, Newman D, Tonnesen MG, Mosesson MW, Clark RA: Human fibroblasts bind directly to fibrinogen at RGD sites through integrin α(v)ß3. Exp Cell Res 232:118, 1997
33. Pizzo SV, Taylor LM Jr, Schwartz ML, Hill RL, McKee PA: Subunit structure of fragment D from fibrinogen and cross-linked fibrin. J Biol Chem 248:4584, 1973
34. Francis CW, Marder VJ, Barlow GH: Plasmic degradation of crosslinked fibrin. J Clin Invest 66:1033, 1980
35. Zhang Z, Fuentes NL, Fuller GM: Characterization of the IL-6 responsive elements in the gamma fibrinogen gene promoter. J Biol Chem 270:24287, 1995
36. Liu A, Fuller GM: Detection of a novel transcription factor for the Aα fibrinogen gene in response to interleukin-6. J Biol Chem 270:7580, 1995
37. Zar JH: Biostatistical Analysis. Englewood Cliffs, NJ, Prentice-Hall, 1984
38. Keeton MR, Curriden SA, van Zonneveld A, Loskutoff D: Identification of regulatory sequences in the type 1 plasminogen activator inhibitor gene responsive to transforming growth factor β. J Biol Chem 266:23048, 1991
39. Knudsen H, Olesen T, Riccio A, Ungaro P, Christensen L, Andreasen PA: A common response element mediates differential effects of phorbol esters and forskolin on type-1 plasminogen activator inhibitor gene expression in human breast carcinoma cells. Eur J Biochem 220:63, 1994
40. Descheemaeker KA, Wyns S, Nelles L, Auwerx J, Ny T, Collen D: Interaction of AP-1-, AP-2, and Sp1-like proteins with two distinct sites in the upstream regulatory region of the plasminogen activator inhibitor-1 gene mediates the phorbol 12-myristate 13-acetate response. J Biol Chem 267:15086, 1992
41. Ryan MP, Higgins PJ: Growth state-regulation expression of p52(PAI-1) in normal rat kidney cells. J Cell Physiol 155:376, 1993
42. Angel P, Karin M: The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation [review]. Biochim Biophys Acta 1072:129, 1991
43. Lau LF, Nathans D: Expression of a set of growth-related immediate early genes in BALB/c 3T3 cells: Coordinate regulation with c-fos or c-myc. Proc Natl Acad Sci USA 84:1182, 1987
44. Brown JR, Nigh E, Lee RJ, Ye H, Thompson MA, Saudo F, Pestell RG, Greenberg ME: Fos family members induce cell cycle entry by activating cyclin Dl. Mol Cell Biol 18:5609, 1998
45. Kovary K, Bravo R: The Jun and Fos protein families are both required for cell cycle progression in fibroblasts. Mol Cell Biol 11:4466, 1991
46. Johnson RS, Van Lingen B, Papaioannou VE, Spiegelman BM: A null mutation at the c-jun locus causes embryonic lethality and retarded cell growth in culture. Genes Dev 7:1309, 1993
47. Deng G, Curriden SA, Wang S, Rosenberg S, Loskutoff DJ: Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release. J Cell Biol 134:1563, 1996
48. Odrljin TM, Shainoff JR, Lawrence SO, Simpson-Haidaris PJ: Thrombin cleavage enhances exposure of a heparin binding domain in the N-terminus of the fibrin β chain. Blood 88:2050, 1996
49. Erban JK, Wagner DD: A 130-kDa protein on endothelial cells binds to amino acids 15-42 of the Bβ chain of fibrinogen. J Biol Chem 267:2451, 1992
50. Bini A, Kudryk BJ: Fibrinogen and fibrin in the arterial wall [review]. Thromb Res 75:337, 1994
51. Bini A, Fenoglio J, Sobel J, Owen J, Fejgl M, Kaplan KL: Immunochemical characterization of fibrinogen, fibrin I, and fibrin II in human thrombi and atherosclerotic lesions. Blood 69:1038, 1987
52. Davis RJ: The mitogen-activated protein kinase signal transduction pathway. J Biol Chem 268:14553, 1993
53. Claret FX, Hibi M, Dhut S, Toda T, Karin M: A new group conserved coactivators that increase the specificity of AP-1 transcription factors. Nature 383:453, 1996
54. Karin M: The regulation of AP-1 activity by mitogen-activated protein kinases [review]. J Biol Chem 270:16483, 1995
55. Romer J, Bugge TH, Pyke C, Lund LR, Flick MJ, Degen JL, Dano K: Imparied wound healing in mice with a disrupted plasminogen gene. Nat Med 2:287, 1996