Characterization of a novel cdk1-related kinase

European Journal of Biochemistry

Volumn 264, Issue 1, 1999, Pages 55-66

  Détivaud, Lénaïck ^a   Pettit, George R ^b   Meijer, Laurent ^a  

^a STATION BIOLOGIQUE   (France)

^b ARIZONA STATE UNIVERSITY   (United States)

Author keywords

Cdc2; Cdk BP; Cell cycle; CKS; CKShsl; Cyclin dependent kinases; HMG I; PSTAIRE; Suc1

Indexed keywords

CROSS REACTING ANTIBODY; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; OLOMOUCINE; PROTEIN P15; PROTEIN P16; PROTEIN P21; ROSCOVITINE;

ARTICLE; CROSS REACTION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME SUBUNIT; NONHUMAN; PRIORITY JOURNAL; PROTEIN IMMOBILIZATION; PROTEIN INTERACTION; SEA URCHIN;

ANIMALS; CYCLIN-DEPENDENT KINASES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; EMBRYONIC DEVELOPMENT; ENZYME INHIBITORS; FEMALE; OOCYTES; PROPHASE; PROTEIN BINDING; SEA URCHINS; STARFISH; XENOPUS;

ECHINOIDEA; MAMMALIA;

EID: 0033567322     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1999.00576.x     Document Type: Article

References (61)

1. 1. Meijer, L., Guidet, S., & Philippe, M. (eds) (1997) Progress in Cell Cycle Research. Vol. 3, pp. 1-321, Plenum Press, London.
2. 2. Morgan, D.O. (1997) Cyclin-dependent kinases: engines, clocks, and microprocessors. Ann. Rev. Cell Dev. Biol. 13, 261-291.
3. 3. Nurse, P. & Bissett, Y. (1981) Gene required in G1 for committment to cell cycle and in G2 for control of mitosis in fission yeast. Nature 292, 558-560.
4. 4. Reed, S.I. (1980) The selection of S. cerevisiae mutants defective in start event of cell division. Genetics 95, 561-577.
5. 5. Hunter, T. &Plowman, G.D. (1997) The protein kinases of budding yeast: Six score and more. Trends Biochem. Sci. 22, 18-22.
6. 6. Lee, M.G. & Nurse, P. (1987) Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2. Nature 237, 31-35.
7. 7. Mironov, V., Van Montagu, M. & Inze, D. (1997) Regulation of cell division in plants: an Arabidopsis perspective. Prog. Cell Cycle Res. 3, 29-41.
8. cdc2, catalytic subunit of maturation-promoting factor and key regulator of the cell cycle. Develop. Growth Differ. 33, 617-624.
9. 9. Meyerson, M., Enders, G.H., Wu, C.L., Su, L.K., Gorka, C., Nelson, C., Harlow, E. & Tsai, L.H. (1992) A family of human cdc2-related protein kinases. EMBO J. 11, 2909-2917.
10. 10. Wei, P., Garber, M.E., Fang, S.M., Fischer, W.H. & Jones, K.A. (1998) A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA. Cell 92, 451-462.
11. 11. Okuda, T., Cleveland, J.L. & Downing, J.R. (1992) PCTAIRE-I and PCTAIRE-3, 2 members of a novel cdc2/CDC28-related protein kinase gene family. Oncogene 7, 2249-2258.
12. 12. Bunnell, B.A., Heath, L.S., Adams, D.E., Lahti, J.M. & Kidd, V.J. (1990). Increased expression of a 58-kDa protein kinase leads to changes in the CHO cell cycle. Proc. Natl Acad. Sci. USA 87, 7467-7471.
13. 13. Xiang, J., Lahti, J.M., Grenet, J., Easton, J. & Kidd, V.J. (1994) Molecular cloning and expression of alternatively spliced PITSLRE protein kinase isoforms. J. Biol. Chem. 269, 15786-15794.
14. 14. Lazzaro, M.A., Albert, P.R. & Julien, J.P. (1997) A novel cdc2-related protein kinase expressed in the nervous system. J. Neurochem. 69, 348-364.
15. 15. Lapidot-Lifson, Y., Patinkin, D., Prody, C.A., Ehrlich, G., Seidman, S., Ben-Aziz, R., Benseler, F., Eckstein, F., Zakut, H. & Soreq, H. (1992) Cloning and antisense oligodeoxynucleotide inhibition of a human homolog of cdc2 required in hematopoiesis. Proc. Natl Acad. Sci. USA 89, 579-583.
16. 16. Brambilla, R. & Draetta, G. (1994) Molecular cloning of PISSLRE, a novel putative member of the cdk family of protein serine/threonine kinases. Oncogene 9, 3037-3041.
17. 17. Rhee, K. & Wolgemuth, D.J. (1995) Cdk family genes are expressed not only in dividing but also in terminally differentiated mouse germ cells, suggesting their possible function during both cell division and differentiation. Dev. Dynamics 204, 406-420.
18. 18. Hirose, T., Tamaru, T., Okumura, N., Nagai, K. & Okada, M. (1997) PCTAIRE 2, a Cdc2-related serine/threonine kinase, is predominantly expressed in terminally differentiated neurons. Eur. J. Biochem. 249, 481-488.
19. 19. Lahti, J.M., Xiang, J.L., Heath, L.S., Campana, D. & Kidd, V.J. (1995) PITSLRE protein kinase activity is associated with apoptosis. Mol. Cell. Biol. 15, 1-11.
20. 20. Beyaert, R., Kidd, V.J., Cornelis, S., Van de Craen, M., Denecker, G., Lahti, J.M., Gururajan, R., Vandenabeele, P. & Fiers, W. (1997) Cleavage of PITSLRE kinases by ICE/CASP-1 and CPP. 32/CASP-3 during apoptosis induced by tumor necrosis factor. J. Biol. Chem. 272, 11694-11697.
21. 21. Hayles, J., Aves, S. & Nurse, P. (1986) Sucl is an essential gene involved in both the cell cycle and growth in fission yeast. EMBO J. 5, 3373-3379.
22. 22. Hadwiger, J.A., Wittenberg, C., Mendenhall, M.D. & Reed, S.I. (1989) The Saccharomyces cerevisiae CKSI gene, a homolog of the Schizosaccharomyces pombe sucl+ gene, encodes a subunit of the CDC28 protein kinase complex. Mol Cell. Biol. 9, 2034-2041.
23. cdc28/cdc2 associated protein of Saccharomyces cerevisiae and Schizosaccharomyces pombe. Genes Dev. 4, 1332-1344.
24. 24. Vogel, L. & Baratte, B. (1996) Sucl: Cdc2 affinity reagent or essential cdk adaptor protein? In Prog. Cell Cycle Res. Vol. 2, 129-135, Plenum Press, London.
25. 25. Bourne, Y., Watson, M.H., Hickey, M.J., Holmes, W., Rocque, W., Reed, S.I. & Trainer, J.A. (1996) Crystal structure and mutational analysis of the human CDK2 kinase complex with cell cycle-regulatory protein CksHs1. Cell 84, 863-874.
26. +. Cell 50, 319-325.
27. cdc2 protein kinase during mitosis. Cell 58, 361-372.
28. ckshs2. Eur. J. Biochem. 203, 353-360.
29. 29. Elledge, S.J., Richman, R., Hall, F.L., Williams, R.T., Lodgson, N. & Harper, J.W. (1992) Cdk2 encodes a 33-kda cyclin-A-associated protein kinase and is expressed before cdc2 in the cell cycle. Proc. Natl Acad. Sci. USA 89, 2907-2911.
30. 30. Tang, Y. & Reed, S.I. (1993) The Cdk-associated protein Cks 1 funtions both in G1 and G2 in Saccharomyces cerevisiae. Genes Dev. 7, 822-832.
31. 31. Basi, G. & Draetta, G. (1995) pl3 (suc1) of Schizosaccharomyces pombe regulates two distinct forms of the mitotic cdc2 kinase. Mol. Cell. Biol. 15, 2028-2036.
32. 32. Hindley, J., Phear, G., Stein, M. & Beach, D. (1987) Suc1+ encodes a predicted 13-kilodalton protein that is essential for cell viability and is directly involved in the division cycle of Schizosaccharomyces pombe. Mol. Cell. Biol. 7, 504-511.
33. 33. Patra, D. & Dunphy, W.G. (1996) Xe-p9, a Xenopus Suc 1/Cks homolog, has multiple essential roles in cell cycle control. Genes Dev. 10, 1503-1515.
34. 34. Sudakin, V., Shteinberg, M., Ganoth, D., Hershko, J. & Hershko, A. (1997) Binding of activated cyclosome to p13 (suc1) - use for affinity purification. J. Biol. Chem. 272, 18051-18059.
35. 35. Egan, E.A. & Solomon, M.J. (1998) Cyclin-stimulated binding of Cks proteins to cyclin-dependent kinases. Mol. Cell. Biol. 18, 3659-3667.
36. 36. Parge, H.E., Arvai, A.S., Murtari, D.J., Reed, S.I. & Tainer, J.A. (1993) Human CksHs2 atomic structure: a role for its hexameric assembly in cell cycle control. Science 262, 387-395.
37. cdc2-interacting cell cycle control protein. EMBO J. 14, 1004-1014.
38. 38. Watson, M.H., Bourne, Y., Arvai, A.S., Hickey, M.J., Santiago, A., Bernstein, S.L., Tainer, J.A. & Reed, S.I. (1996) A mutation in the human cyclin-dependent kinase interacting protein, CksHs2, interferes with cyclin-dependent kinase binding and biological function, but preserves protein structure and assembly. J. Mol. Biol. 261, 646-657.
39. 39. Azzi, L., Meijer, L., Ostvold, A.C., Lew, J. & Wang, J.H. (1994) Purification of a 15-kDa cdk4-and cdk5-binding protein. J. Biol. Chem. 269, 13279-13288.
40. 40. Pettit, G.R., Herald, C.L., Leet, J.E., Gupta, R., Schaufelberger, D.E., Bates, R.B., Clewlow, P.J., Doubek, D.L., Manfredi, K.P., Rutzier, K., Schmidt, J.M., Tackett, L.P., Ward, F.B., Bruck, M. & Camou, F. (1990) Antineoplastic agents 168. Isolation and structure of axinohydantoin. Can. J. Chem. 68, 1621-1624.
41. 41. Kato, J., Matsushime, H., Hiebert, S.W., Ewen, M.E. & Sherr, C.J. (1993) Direct binding of cyclin-D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4. Genes Dev. 7, 331-342.
42. 42. Meijer, L., Pondaven, P., Guerrier, P. & Moreau, M. (1986) A starfish oocyte user's guide. Cah. Biol. Mar. 25, 457-480.
43. 43. Ford, C.C. & Gurdon, J.B. (1977) A method for enucleating oocytes of Xenopus laevis. J. Embryol. Exp. Morphol. 37, 203-209.
44. cdc2 on Thr-14 and Tyr-15 at the prophase/metaphase transition. J. Biol. Chem. 271, 27847-27854.
45. cdc13 kinase. Eur. J. Biochem. 196, 557-567.
46. 46. Vesely, J., Havlicek, L., Strnad, M., Blow, J.J., Donelladeana, A., Pinna, L., Letham, D.S., Kato, J., Detivaud, L., Leclerc, S. & Meijer. L. (1994) Inhibition of cyclin-dependent kinases by purine analogues. Eur. J. Biochem. 224, 771-786.
47. 47. Meijer, L., Borgne, A., Mulner, O., Chong, J.P.J., Blow, J.J., Inagaki, N., Inagaki, M., Deleros, J.G. & Moulinoux, J.P. (1997) Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5. Eur. J. Biochem. 243, 527-536.
48. 48. Gray, N.S., Wodicka, L., Thunnissen, A.M.W.H., Norman, T.C., Kwon, S.J., Espinoza, F.H., Morgan, D.O., Barnes, G., Leclerc, S., Meijer, L., Kim, S.H., Lockhart, D.J. & Schultz, P.G. (1998) Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors. Science 281, 533-538.
49. 49. Meijer, L., Arion, D., Golsteyn, R., Pines, J., Brizuela, L., Hunt, T. & Beach, D. (1989) Cyclin is a component of the sea urchin egg M-phase specific histone H1 kinase. EMBO J. 8, 2275-2282.
50. 50. Kaffman, A., Herskowitz, I., Tjian, R. & Oshea, E.K. (1994) Phosphorylation of the transcription factor-PHO4 by a cyclin-CDK complex, PHO80-PHO85. Science 263, 1153-1156.
51. 51. Besset, V., Rhee, K. & Wolgemuth, D.J. (1998) The identification and characterization of expression of Pftaire-1, a novel Cdk family member, suggest its function in the mouse testis and nervous system. Mol. Reprod. Dev. 50, 18-29.
52. 52. De Luca, A., Esposito, V., Baldi, A., Claudio, P.P., Fu, Y., Caputi, M., Pisano, M.M., Baldi, F. & Giordano, A. (1997) CDC2-related kinase PITALRE phosphorylates pRB exclusively on serine and is widely expressed in human tissues. J. Cell. Physiol. 172, 265-273.
53. 53. Bagella, L., MacLachlan, T.K., Buono, R.J., Pisano, M.M., de Giordano, A. & Luca, A. (1998) Cloning of murine CDK9/PITALRE and its tissue-specific expression in development. J. Cell. Physiol. 177, 206-213.
54. 54. So, K., Katz, S. & Pelech, S.L. (1998) Expression of second messenger and cyclin-dependent protein kinases during postnatal development of rat heart. J. Cell Biol. 69, 506-521.
55. 55. Yen, S.H., Kenessey, A., Lee, S.C. & Dickson, D.W. (1995) The distribution and biochemical properties of a cdc2-related kinase, KKIALRE, in normal and alzheimer brains. J. Neurochem. 65, 2577-2584.
56. 56. Taglienti, C.A., Wysk, M. & Davis, R.J. (1996) Molecular cloning of the epidermal growth factor-stimulated protein kinase p56 KKIAMRE. Oncogene 13, 2563-2574.
57. 57. Xiang, J.L., Lahti, J.M. & Kidd, V.J. (1994) 2-Aminopurine overrides a late telophase delay created by ectopic expression of the PITSLRE β 1 protein kinase. Biochem. Biophys. Res. Commun. 199, 1167-1173.
58. 58. Grana, X., Deluca, A., Sang, N., Fu, Y., Claudio, P.P., Rosenblatt, J., Morgan, D.O. & Giordano, A. (1994) Pitalre, a nuclear cdc2-related protein kinase that phosphorylates the retinoblastoma protein in vitro. Proc. Natl Acad. Sci. USA 91, 3834-3838.
59. 59. Measday, V., Moore, L., Ogas, J., Tyers, M. & Andrews, B. (1994) The PCL2 (ORFD) -PHO85 cyclin-dependent kinase complex: a cell cycle regulator in yeast. Science 266, 1391-1395.
60. 60. Espinoza, F.H., Ogas, J., Herskowitz, I. & Morgan, D.O. (1994) Cell cycle control by a complex of the cyclin HCS26 (PCL I) and the kinase PHO85. Science 266, 1388-1391.
61. 61. Bussink, H.J. & Osmani, S.A. (1998) A cyclin-dependent kinase family member (PHOA) is required to link developmental fate to environmental conditions in Aspergillus nidulans. EMBO J. 17, 3990-4003.