메뉴 건너뛰기




Volumn 59, Issue 16, 1999, Pages 4111-4118

Inhibition of bladder carcinoma angiogenesis, stromal support, and tumor growth by halofuginone

Author keywords

[No Author keywords available]

Indexed keywords

HALOFUGINONE;

EID: 0033566986     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (96)

References (46)
  • 1
    • 0002956456 scopus 로고
    • Tumor stroma
    • R. Colvin, A. Bhan, and R. McCluskey (eds.), New York: Raven Press
    • Yeo, T-K., and Dvorak, H. F. Tumor stroma. In: R. Colvin, A. Bhan, and R. McCluskey (eds.), Diagnostic Immunopathology, Ed. 2, pp. 685-697. New York: Raven Press, 1995.
    • (1995) Diagnostic Immunopathology, Ed. 2 , pp. 685-697
    • Yeo, T.-K.1    Dvorak, H.F.2
  • 2
    • 0026639806 scopus 로고
    • Angiogenesis
    • Folkman, J., and Shing, Y. Angiogenesis. J. Biol. Chem., 267: 10931-10934, 1992.
    • (1992) J. Biol. Chem. , vol.267 , pp. 10931-10934
    • Folkman, J.1    Shing, Y.2
  • 3
    • 0026846928 scopus 로고
    • The role of angiogenesis in tumor growth
    • Folkman, J. The role of angiogenesis in tumor growth. Semin. Cancer Biol., 3: 65-71, 1992.
    • (1992) Semin. Cancer Biol. , vol.3 , pp. 65-71
    • Folkman, J.1
  • 4
    • 0001924046 scopus 로고
    • Extracellular matrix-bound growth factors, enzymes and plasma proteins
    • D. H. Rohrbach and R. Timpl (eds.), Orlando, FL: Academic Press
    • Vlodavsky, I., Bar-Shavit, R., Korner, G., and Fuks, Z. Extracellular matrix-bound growth factors, enzymes and plasma proteins. In: D. H. Rohrbach and R. Timpl (eds.), Basement Membranes: Cellular and Molecular Aspects, pp. 327-343. Orlando, FL: Academic Press, 1993.
    • (1993) Basement Membranes: Cellular and Molecular Aspects , pp. 327-343
    • Vlodavsky, I.1    Bar-Shavit, R.2    Korner, G.3    Fuks, Z.4
  • 5
    • 0021079540 scopus 로고
    • Tumor invasion and extracellular matrix
    • Liotta, L. A., Rao, C. N., and Barsky, S. H. Tumor invasion and extracellular matrix. Lab. Invest., 49: 636-649, 1983.
    • (1983) Lab. Invest. , vol.49 , pp. 636-649
    • Liotta, L.A.1    Rao, C.N.2    Barsky, S.H.3
  • 6
    • 0026522287 scopus 로고
    • The role of proteolytic enzymes in cancer invasion and metastasis
    • Duffy, M. J. The role of proteolytic enzymes in cancer invasion and metastasis. Clin. Exp. Metastasis, 10: 145-155, 1992.
    • (1992) Clin. Exp. Metastasis , vol.10 , pp. 145-155
    • Duffy, M.J.1
  • 7
    • 0025611427 scopus 로고
    • Type IV collagenases in tumor invasion and metastasis
    • Stetler-Stevenson, W. G. Type IV collagenases in tumor invasion and metastasis. Cancer Metastasis Rev., 9: 289-303, 1990.
    • (1990) Cancer Metastasis Rev. , vol.9 , pp. 289-303
    • Stetler-Stevenson, W.G.1
  • 8
    • 0027333411 scopus 로고
    • Tumor cell interactions with the extracellular matrix during invasion and metastasis
    • Stetler-Stevenson, W. G., Aznavoorian, S., and Liotta, L. A. Tumor cell interactions with the extracellular matrix during invasion and metastasis. Annu. Rev. Cell Biol., 9: 541-573, 1993.
    • (1993) Annu. Rev. Cell Biol. , vol.9 , pp. 541-573
    • Stetler-Stevenson, W.G.1    Aznavoorian, S.2    Liotta, L.A.3
  • 10
    • 0029908587 scopus 로고    scopus 로고
    • Prognostic significance of circulating matrix metalloproteinase-2 to tissue inhibitor of metalloproteinases-2 ratio in recurrence of urothelial cancer after complete resection
    • Gohji, K., Fujimoto, N., Fujii, A., Komiyama, T., Okawa, J., and Nakajima, M. Prognostic significance of circulating matrix metalloproteinase-2 to tissue inhibitor of metalloproteinases-2 ratio in recurrence of urothelial cancer after complete resection. Cancer Res., 56: 3196-3198, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 3196-3198
    • Gohji, K.1    Fujimoto, N.2    Fujii, A.3    Komiyama, T.4    Okawa, J.5    Nakajima, M.6
  • 12
    • 0022979424 scopus 로고
    • Secretion of metalloproteinases by stimulated capillary endothelial cells. Expression of collagenase and stromeolysin activities is regulated by endogenous inhibitors
    • Herron, G. S., Banda, M., Clarck, E. J., Gavrilovic, J., and Werb, Z. Secretion of metalloproteinases by stimulated capillary endothelial cells. Expression of collagenase and stromeolysin activities is regulated by endogenous inhibitors. J. Biol. Chem., 261: 2814-2818, 1986.
    • (1986) J. Biol. Chem. , vol.261 , pp. 2814-2818
    • Herron, G.S.1    Banda, M.2    Clarck, E.J.3    Gavrilovic, J.4    Werb, Z.5
  • 13
    • 0025351278 scopus 로고
    • Identification of an inhibitor of neovascularization from cartilage
    • Washington DC
    • Moses, M. A., Sudhalter, J., and Langer, R. Identification of an inhibitor of neovascularization from cartilage. Science (Washington DC), 248: 1408-1410, 1990.
    • (1990) Science , vol.248 , pp. 1408-1410
    • Moses, M.A.1    Sudhalter, J.2    Langer, R.3
  • 15
    • 0025139833 scopus 로고
    • Vectorial secretion of extracellular matrix proteins, matrix-degrading proteinases, and tissue inhibitor of metalloproteinases by endothelial cells
    • Unemori, E. N., Bouhana, K. S., and Werb, Z. Vectorial secretion of extracellular matrix proteins, matrix-degrading proteinases, and tissue inhibitor of metalloproteinases by endothelial cells. J. Biol. Chem., 265: 445-451, 1990.
    • (1990) J. Biol. Chem. , vol.265 , pp. 445-451
    • Unemori, E.N.1    Bouhana, K.S.2    Werb, Z.3
  • 16
    • 0028000141 scopus 로고
    • Inhibition of AIDS-Kaposi's sarcoma cell induced endothelial cell invasion by TIMP-2 and a synthetic peptide from the metalloproteinase propeptide: Implications for an anti-angiogenic therapy
    • Benelli, R., Adatia, R., Ensoli, B., Stetler-Stevenson, W. G., Santi, L., and Albini, A. Inhibition of AIDS-Kaposi's sarcoma cell induced endothelial cell invasion by TIMP-2 and a synthetic peptide from the metalloproteinase propeptide: implications for an anti-angiogenic therapy. Oncol. Res., 6: 251-257, 1994.
    • (1994) Oncol. Res. , vol.6 , pp. 251-257
    • Benelli, R.1    Adatia, R.2    Ensoli, B.3    Stetler-Stevenson, W.G.4    Santi, L.5    Albini, A.6
  • 18
    • 0026199498 scopus 로고
    • Increased skin tearing in broilers and reduced collagen synthesis in vivo and in vitro in response to the coccidiostat halofuginone
    • Granot, I., Bartov, I., Davnik, I., Wax, E., Hurwitz, S., and Pines, M. Increased skin tearing in broilers and reduced collagen synthesis in vivo and in vitro in response to the coccidiostat halofuginone. Poult. Sci., 70: 1559-1563, 1991.
    • (1991) Poult. Sci. , vol.70 , pp. 1559-1563
    • Granot, I.1    Bartov, I.2    Davnik, I.3    Wax, E.4    Hurwitz, S.5    Pines, M.6
  • 19
    • 0027469572 scopus 로고
    • Halofuginone: An inhibitor of collagen type I synthesis
    • Granot, I., Halevy, O., Hurwitz, S., and Pines, M. Halofuginone: an inhibitor of collagen type I synthesis. Biochem. Biophys. Acta, 1156: 107-112, 1993.
    • (1993) Biochem. Biophys. Acta , vol.1156 , pp. 107-112
    • Granot, I.1    Halevy, O.2    Hurwitz, S.3    Pines, M.4
  • 20
    • 0030580036 scopus 로고    scopus 로고
    • Inhibition of collagenase type I synthesis by skin fibroblasts of graft versus host disease and scleroderma patients: Effect of halofuginone
    • Halevy, O., Nagler, A., Levi-Schaffer, F., Genina, O., and Pines, M. Inhibition of collagenase type I synthesis by skin fibroblasts of graft versus host disease and scleroderma patients: effect of halofuginone. Biochem. Pharmacol., 52: 1057-1062, 1996.
    • (1996) Biochem. Pharmacol. , vol.52 , pp. 1057-1062
    • Halevy, O.1    Nagler, A.2    Levi-Schaffer, F.3    Genina, O.4    Pines, M.5
  • 21
    • 0031028794 scopus 로고    scopus 로고
    • Inhibition of collagen synthesis, smooth muscle cell proliferation and injury-induced intimal hyperplasia by halofuginone
    • Nagler, A., Miao, H-Q., Aingorn, E,. Pines, M., Genina, O., and Vlodavsky, I. Inhibition of collagen synthesis, smooth muscle cell proliferation and injury-induced intimal hyperplasia by halofuginone. Arterioscler. Thromb. Vasc. Biol., 17: 194-202, 1997.
    • (1997) Arterioscler. Thromb. Vasc. Biol. , vol.17 , pp. 194-202
    • Nagler, A.1    Miao, H.-Q.2    Aingorn, E.3    Pines, M.4    Genina, O.5    Vlodavsky, I.6
  • 22
    • 0031434767 scopus 로고    scopus 로고
    • Inhibition of glomerular mesangial cell proliferation and extracellular matrix deposition by halofuginone
    • Nagler, A., Katz, A., Aingorn, E., Miao, H-Q., Condiotti, R., Genina, O., Pines, M., and Vlodavsky, I. Inhibition of glomerular mesangial cell proliferation and extracellular matrix deposition by halofuginone. Kidney Int., 52: 1561-1569, 1997.
    • (1997) Kidney Int. , vol.52 , pp. 1561-1569
    • Nagler, A.1    Katz, A.2    Aingorn, E.3    Miao, H.-Q.4    Condiotti, R.5    Genina, O.6    Pines, M.7    Vlodavsky, I.8
  • 24
    • 0017064608 scopus 로고
    • Different susceptibilities of the urinary bladder epithelium of animal species to three nitroso compounds
    • Hirose, M., Fukushima, S., Hananouchi, M., Shirai, T., Ogiso, T., Takahashi, M., and Ito, N. Different susceptibilities of the urinary bladder epithelium of animal species to three nitroso compounds. Gann, 67: 175-189, 1976.
    • (1976) Gann , vol.67 , pp. 175-189
    • Hirose, M.1    Fukushima, S.2    Hananouchi, M.3    Shirai, T.4    Ogiso, T.5    Takahashi, M.6    Ito, N.7
  • 25
    • 0022647132 scopus 로고
    • Sequential changes of mouse bladder epithelium during induction of invasive carcinomas by N-butyl-N-(4-hydroxybutyl)nitrosamine
    • Ohtani, M., Kakizoe, T., Nisio, Y., Sato, S., Sugimura, T., Fukushima, S., and Nijima, T. Sequential changes of mouse bladder epithelium during induction of invasive carcinomas by N-butyl-N-(4-hydroxybutyl)nitrosamine. Cancer Res., 46: 2001-2004, 1986.
    • (1986) Cancer Res. , vol.46 , pp. 2001-2004
    • Ohtani, M.1    Kakizoe, T.2    Nisio, Y.3    Sato, S.4    Sugimura, T.5    Fukushima, S.6    Nijima, T.7
  • 26
    • 0032405505 scopus 로고    scopus 로고
    • The dynamics of the imprinted H19 gene expression in the mouse model of bladder carcinoma induced by N-butyl-N-(4-hydroxybutil)nitrosamine
    • Lond.
    • Elkin, M., Ayesh, S., Schneider, T., de-Groot, N., Hochberg, A., and Ariel, I. The dynamics of the imprinted H19 gene expression in the mouse model of bladder carcinoma induced by N-butyl-N-(4-hydroxybutil)nitrosamine. Carcinogenesis (Lond.), 19: 2095-2099, 1998.
    • (1998) Carcinogenesis , vol.19 , pp. 2095-2099
    • Elkin, M.1    Ayesh, S.2    Schneider, T.3    De-Groot, N.4    Hochberg, A.5    Ariel, I.6
  • 28
    • 18544405060 scopus 로고    scopus 로고
    • H19 overexpression in breast adenocarcinoma stromal cells is associated with tumor values and steroid receptor status but independent of p53 and Ki-67 expression
    • Adriaenssens, E., Dumont, I., Lottin, S., Bolle, D., Lepretre, A., Delobelle, A., Bouali, F., Dugimom, T., Coll, J., and Curgy, J. J. H19 overexpression in breast adenocarcinoma stromal cells is associated with tumor values and steroid receptor status but independent of p53 and Ki-67 expression. Am. J. Pathol., 153: 1597-1607, 1998.
    • (1998) Am. J. Pathol. , vol.153 , pp. 1597-1607
    • Adriaenssens, E.1    Dumont, I.2    Lottin, S.3    Bolle, D.4    Lepretre, A.5    Delobelle, A.6    Bouali, F.7    Dugimom, T.8    Coll, J.9    Curgy, J.J.10
  • 30
    • 0031053304 scopus 로고    scopus 로고
    • Anti-neoplastic activity of paclitaxel on experimental superficial bladder cancer: In vivo and in vitro studies
    • Nativ, O., Aronson, M., Medalia, O., Moldavsky, T., Sabo, E., Ringel, I., and Kravtsov, V. Anti-neoplastic activity of paclitaxel on experimental superficial bladder cancer: in vivo and in vitro studies. Int. J. Cancer, 70: 297-301, 1997.
    • (1997) Int. J. Cancer , vol.70 , pp. 297-301
    • Nativ, O.1    Aronson, M.2    Medalia, O.3    Moldavsky, T.4    Sabo, E.5    Ringel, I.6    Kravtsov, V.7
  • 31
    • 0029763274 scopus 로고    scopus 로고
    • Treatment of experimental mouse bladder tumor by LPS-induced epithelial cell shedding
    • Nativ, O., Medalia, O., Mor, Y., Shajrawi, I., Sabo, E., and Aronson, M. Treatment of experimental mouse bladder tumor by LPS-induced epithelial cell shedding. Br. J. Cancer, 74: 603-605, 1996.
    • (1996) Br. J. Cancer , vol.74 , pp. 603-605
    • Nativ, O.1    Medalia, O.2    Mor, Y.3    Shajrawi, I.4    Sabo, E.5    Aronson, M.6
  • 32
    • 0020016572 scopus 로고
    • Collagen as a substrate for cell growth and differentiation
    • Strom, S. C., and Michalopoulos, G. Collagen as a substrate for cell growth and differentiation. Methods Enzymol. 82: 544-555, 1982.
    • (1982) Methods Enzymol. , vol.82 , pp. 544-555
    • Strom, S.C.1    Michalopoulos, G.2
  • 33
    • 0015402532 scopus 로고
    • Collagen substrata for studies on cell behavior
    • Elsdale, T., and Bard, J. Collagen substrata for studies on cell behavior. J. Cell Biol. 54: 626-637, 1972.
    • (1972) J. Cell Biol. , vol.54 , pp. 626-637
    • Elsdale, T.1    Bard, J.2
  • 34
    • 0025364195 scopus 로고
    • Growth of microvessels in serum-free matrix culture of rat aorta
    • Nicosia, R. F., and Ottinetti, A. Growth of microvessels in serum-free matrix culture of rat aorta. Lab. Invest. 63: 115-122, 1990.
    • (1990) Lab. Invest. , vol.63 , pp. 115-122
    • Nicosia, R.F.1    Ottinetti, A.2
  • 35
    • 0030759740 scopus 로고    scopus 로고
    • Halofuginone, a specific inhibitor of collagen type I synthesis, prevents dimethylnitrosamine-induced liver cirrhosis
    • Pines, M., Knopov, V., Genina, O., Lavelin, I., and Nagler, A. Halofuginone, a specific inhibitor of collagen type I synthesis, prevents dimethylnitrosamine-induced liver cirrhosis. J. Hepatol., 27: 391-398, 1997.
    • (1997) J. Hepatol. , vol.27 , pp. 391-398
    • Pines, M.1    Knopov, V.2    Genina, O.3    Lavelin, I.4    Nagler, A.5
  • 36
    • 0031928721 scopus 로고    scopus 로고
    • Halofuginone - An inhibitor of collagen type I synthesis - Prevents post-operative formation of abdominal adhesions
    • Nagler, A., Rivkind, A., Raphael, J., Levi-Schaffer, F., Genina, O., Lavelin, I., and Pines, M. Halofuginone - an inhibitor of collagen type I synthesis - prevents post-operative formation of abdominal adhesions. Ann. Surg. 227: 575-582, 1998.
    • (1998) Ann. Surg. , vol.227 , pp. 575-582
    • Nagler, A.1    Rivkind, A.2    Raphael, J.3    Levi-Schaffer, F.4    Genina, O.5    Lavelin, I.6    Pines, M.7
  • 37
    • 0001432887 scopus 로고    scopus 로고
    • Detection of halofuginone residues in chicken liver tissue by HPLC and a monoclonal-based immunoassay
    • Beier, R. C., Dutco, T. J., Buckley, S. A., Muldoon, M. T., Holtzappe, C. K., and Stanker, L. H. Detection of halofuginone residues in chicken liver tissue by HPLC and a monoclonal-based immunoassay. J. Agric. Food Chem. 46: 1049-1054, 1998.
    • (1998) J. Agric. Food Chem. , vol.46 , pp. 1049-1054
    • Beier, R.C.1    Dutco, T.J.2    Buckley, S.A.3    Muldoon, M.T.4    Holtzappe, C.K.5    Stanker, L.H.6
  • 38
    • 0024760499 scopus 로고
    • Pharmacokinetics of halofuginone in cattle
    • Kinabo, L. D., and McKellar, Q. A. Pharmacokinetics of halofuginone in cattle. Br. Vet. J., 145: 546-551, 1989.
    • (1989) Br. Vet. J. , vol.145 , pp. 546-551
    • Kinabo, L.D.1    McKellar, Q.A.2
  • 40
    • 0001176281 scopus 로고    scopus 로고
    • A dose-finding study of marimastat, an oral matrix metalloproteinase inhibitor, in patients with advanced colorectal cancer
    • Primrose, J., Bleiberg, H., Daniel, F., Johnson, P., Mansi, J., Neoptolemos, J., Seymour, M., and Van Belle, S. A dose-finding study of marimastat, an oral matrix metalloproteinase inhibitor, in patients with advanced colorectal cancer. Ann. Oncol. 7: 35, 1996.
    • (1996) Ann. Oncol. , vol.7 , pp. 35
    • Primrose, J.1    Bleiberg, H.2    Daniel, F.3    Johnson, P.4    Mansi, J.5    Neoptolemos, J.6    Seymour, M.7    Van Belle, S.8
  • 41
    • 0025811546 scopus 로고
    • Differential expression of extracellular proteins is correlated with angiogenesis in vitro
    • Iruela-Arispe, M. L., Hasselaar, P., and Sage, H. Differential expression of extracellular proteins is correlated with angiogenesis in vitro. Lab. Invest., 64: 174-186, 1991.
    • (1991) Lab. Invest. , vol.64 , pp. 174-186
    • Iruela-Arispe, M.L.1    Hasselaar, P.2    Sage, H.3
  • 42
    • 0025990740 scopus 로고
    • Transcriptional activity of the α 1(I)-collagen promoter is correlated with the formation of capillary-like structures by endothelial cells in vitro
    • Fouser, L., Iruela-Arispe, L., Bornstein, P., and Sage, E. H. Transcriptional activity of the α 1(I)-collagen promoter is correlated with the formation of capillary-like structures by endothelial cells in vitro. J. Biol. Chem., 266: 18345-18351, 1991.
    • (1991) J. Biol. Chem. , vol.266 , pp. 18345-18351
    • Fouser, L.1    Iruela-Arispe, L.2    Bornstein, P.3    Sage, E.H.4
  • 43
    • 0026080462 scopus 로고
    • Type I collagen fibrils promote rapid vascular tube formation upon contact with the apical side of cultured endothelium
    • Jackson, C. J., and Jenkins, K. L. Type I collagen fibrils promote rapid vascular tube formation upon contact with the apical side of cultured endothelium. Exp. Cell Res., 192: 319-323, 1991.
    • (1991) Exp. Cell Res. , vol.192 , pp. 319-323
    • Jackson, C.J.1    Jenkins, K.L.2
  • 44
    • 0028057278 scopus 로고
    • H19, a developmentally regulated gene, is reexpressed in rat vascular smooth muscle cells after injury
    • Kim, D-K., Zang, L., Dzau, V., and Pratt, R. H19, a developmentally regulated gene, is reexpressed in rat vascular smooth muscle cells after injury. J. Clin. Invest. 93: 355-360, 1994.
    • (1994) J. Clin. Invest. , vol.93 , pp. 355-360
    • Kim, D.-K.1    Zang, L.2    Dzau, V.3    Pratt, R.4
  • 45
    • 0029866163 scopus 로고    scopus 로고
    • H19, a marker of developmental transition, is reexpressed in human atherosclerotic plaques and is regulated by the insulin family of growth factors in cultured rabbit smooth muscle cells
    • Han, D. K. H., Khaing, Z., Pollock, R. A., Haudenschild, C. C., and Liau, G. H19, a marker of developmental transition, is reexpressed in human atherosclerotic plaques and is regulated by the insulin family of growth factors in cultured rabbit smooth muscle cells. J. Clin. Invest., 97: 1276-1285, 1996.
    • (1996) J. Clin. Invest. , vol.97 , pp. 1276-1285
    • Han, D.K.H.1    Khaing, Z.2    Pollock, R.A.3    Haudenschild, C.C.4    Liau, G.5
  • 46
    • 0032054482 scopus 로고    scopus 로고
    • Halofuginone: A novel anti-fibrotic therapy
    • Pines, M., and Nagler, A. Halofuginone: a novel anti-fibrotic therapy. Gen. Pharmacol., 30: 445-450, 1998.
    • (1998) Gen. Pharmacol. , vol.30 , pp. 445-450
    • Pines, M.1    Nagler, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.