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Volumn 59, Issue 16, 1999, Pages 3980-3984

The protein kinase C inhibitor CGP41251 suppresses cytokine release and extracellular signal-regulated kinase 2 expression in cancer patients

Author keywords

[No Author keywords available]

Indexed keywords

MIDOSTAURIN; PROTEIN KINASE C INHIBITOR;

EID: 0033566983     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (56)

References (20)
  • 1
    • 0031058595 scopus 로고    scopus 로고
    • Protein kinase C: A worthwhile target for anticancer drugs?
    • Caponigro, F., French, R. C., and Kaye, S. B. Protein kinase C: a worthwhile target for anticancer drugs? Anticancer Drugs, 8: 26-33, 1997.
    • (1997) Anticancer Drugs , vol.8 , pp. 26-33
    • Caponigro, F.1    French, R.C.2    Kaye, S.B.3
  • 2
    • 0027981240 scopus 로고
    • Inhibiting intracellular signalling as a strategy for cancer chemoprevention
    • Powis, G., and Alberts, D. S. Inhibiting intracellular signalling as a strategy for cancer chemoprevention. Eur. J. Cancer, 30A: 1138-1144, 1994.
    • (1994) Eur. J. Cancer , vol.30 A , pp. 1138-1144
    • Powis, G.1    Alberts, D.S.2
  • 3
    • 0021227676 scopus 로고
    • The role of protein kinase C in cell surface signal transduction and tumour promotion
    • Nishizuka, Y. The role of protein kinase C in cell surface signal transduction and tumour promotion. Nature (Lond.), 30S: 693-698, 1984.
    • (1984) Nature (Lond.) , vol.30 S , pp. 693-698
    • Nishizuka, Y.1
  • 4
    • 0030022970 scopus 로고    scopus 로고
    • Antitumor activity of the new selective protein kinase C inhibitor 4′-N-benzoyl staurosporine on murine and human tumor models
    • Ikegami, Y., Yano, S., Nakao, K., Fujita, F., Sakamoto, Y., Murata, N., and Isowa, K. Antitumor activity of the new selective protein kinase C inhibitor 4′-N-benzoyl staurosporine on murine and human tumor models. Jpn. J. Pharmacol., 70: 65-72, 1996.
    • (1996) Jpn. J. Pharmacol. , vol.70 , pp. 65-72
    • Ikegami, Y.1    Yano, S.2    Nakao, K.3    Fujita, F.4    Sakamoto, Y.5    Murata, N.6    Isowa, K.7
  • 5
    • 0027312987 scopus 로고
    • Staurosporine-related compounds, K252a and UCN-01, inhibit both cPKC and nPKC
    • Mizuno, K., Saido, T. C., Ohno, S., Tamaoki, T., and Suzuki, K. Staurosporine-related compounds, K252a and UCN-01, inhibit both cPKC and nPKC. FEBS Lett., 330: 114-116, 1993.
    • (1993) FEBS Lett. , vol.330 , pp. 114-116
    • Mizuno, K.1    Saido, T.C.2    Ohno, S.3    Tamaoki, T.4    Suzuki, K.5
  • 6
    • 0024379951 scopus 로고
    • A derivative of staurosporine (CGP41 251) shows selectivity for protein kinase C inhibition and in vitro anti-proliferative as well as in vivo anti-tumour activity
    • Meyer, T., Regenass, U., Fabbro, D., Alteri, E., Rosel, J., Muller, M., Caravatti, G., and Matter, A. A derivative of staurosporine (CGP41 251) shows selectivity for protein kinase C inhibition and in vitro anti-proliferative as well as in vivo anti-tumour activity. Int. J. Cancer, 43: 851-856, 1989.
    • (1989) Int. J. Cancer , vol.43 , pp. 851-856
    • Meyer, T.1    Regenass, U.2    Fabbro, D.3    Alteri, E.4    Rosel, J.5    Muller, M.6    Caravatti, G.7    Matter, A.8
  • 9
    • 0028231242 scopus 로고
    • The protein kinase C inhibitor CGP41251, a staurosporine derivative with antitumour activity, reverses multidrug resistance
    • Utz, I., Hofer, S., Regenass, U., Hilbe, W., Thaler, J., Grunicke, H., and Hofmann, J. The protein kinase C inhibitor CGP41251, a staurosporine derivative with antitumour activity, reverses multidrug resistance. Int. J. Cancer, 57: 104-110, 1994.
    • (1994) Int. J. Cancer , vol.57 , pp. 104-110
    • Utz, I.1    Hofer, S.2    Regenass, U.3    Hilbe, W.4    Thaler, J.5    Grunicke, H.6    Hofmann, J.7
  • 10
    • 0029988743 scopus 로고    scopus 로고
    • Comparison of staurosporine and four analogues: Their effects on growth, rhodamine 123 retention and binding of P-glycoprotein in multidrug resistant MCF-7/Adr cells
    • Budworth, J., Davies, R., Malkhandi, J., Gant, T. W., Ferry, D. R., and Gescher, A. Comparison of staurosporine and four analogues: their effects on growth, rhodamine 123 retention and binding of P-glycoprotein in multidrug resistant MCF-7/Adr cells. Br. J. Cancer, 73: 1063-1068, 1998.
    • (1998) Br. J. Cancer , vol.73 , pp. 1063-1068
    • Budworth, J.1    Davies, R.2    Malkhandi, J.3    Gant, T.W.4    Ferry, D.R.5    Gescher, A.6
  • 11
    • 0031012175 scopus 로고    scopus 로고
    • Chemosensitization of cancer cells by the staurosporine derivative CGP41251 in association with decreased P-glycoprotein phosphorylation
    • Beltran, P. J., Fan, D., Fidler, I. J., and O'Brian, C. A. Chemosensitization of cancer cells by the staurosporine derivative CGP41251 in association with decreased P-glycoprotein phosphorylation. Biochem. Pharmacol., 53: 245-247, 1997.
    • (1997) Biochem. Pharmacol. , vol.53 , pp. 245-247
    • Beltran, P.J.1    Fan, D.2    Fidler, I.J.3    O'Brian, C.A.4
  • 12
    • 0028068084 scopus 로고
    • Involvement of protein kinase C and protein tyrosine kinase in lipopolysaccharide-induced TNF-α and IL-1β production by human monocytes
    • Shapira, L., Takashiba, T., Champagne C., Amar S., and Van Dyke, T. E. Involvement of protein kinase C and protein tyrosine kinase in lipopolysaccharide-induced TNF-α and IL-1β production by human monocytes. J. Immunol., 153: 1818-1824, 1994.
    • (1994) J. Immunol. , vol.153 , pp. 1818-1824
    • Shapira, L.1    Takashiba, T.2    Champagne, C.3    Amar, S.4    Van Dyke, T.E.5
  • 13
    • 0028293559 scopus 로고
    • Signal transduction pathways mediating astrocyte IL-6 induction by IL-1β and tumour necrosis factor-α
    • Norris, J. G., Tang, L. P., Sparacio, S. M., and Benveniste, E. N. Signal transduction pathways mediating astrocyte IL-6 induction by IL-1β and tumour necrosis factor-α. J. Immunol., 152: 841-850, 1994.
    • (1994) J. Immunol. , vol.152 , pp. 841-850
    • Norris, J.G.1    Tang, L.P.2    Sparacio, S.M.3    Benveniste, E.N.4
  • 14
    • 0039791449 scopus 로고    scopus 로고
    • Activation of the mitogen-activated protein kinase/extracellular signal-related kinase pathway by conventional, novel, and atypical protein kinase C isotypes
    • Schonwasser, D. C., Marais, R. M., Marshall, C. J., and Parker, P. J. Activation of the mitogen-activated protein kinase/extracellular signal-related kinase pathway by conventional, novel, and atypical protein kinase C isotypes. Mol. Cell. Biol., 18: 790-798, 1998.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 790-798
    • Schonwasser, D.C.1    Marais, R.M.2    Marshall, C.J.3    Parker, P.J.4
  • 15
    • 0026781419 scopus 로고
    • Measuring cytokines in blood: The importance of anticoagulants, processing and storage
    • Thavasu, P., Longhurst, S., Joel, S. P., Slevin, M., and Balkwill, F. R. Measuring cytokines in blood: the importance of anticoagulants, processing and storage. J. Immunol. Methods, 153: 115-124, 1992.
    • (1992) J. Immunol. Methods , vol.153 , pp. 115-124
    • Thavasu, P.1    Longhurst, S.2    Joel, S.P.3    Slevin, M.4    Balkwill, F.R.5
  • 16
    • 0022673130 scopus 로고
    • Longitudinal data analysis for discrete and continuous outcomes
    • Zeger, S. L., and Liang, K. Y. Longitudinal data analysis for discrete and continuous outcomes. Biometrics, 42: 121-130, 1986.
    • (1986) Biometrics , vol.42 , pp. 121-130
    • Zeger, S.L.1    Liang, K.Y.2
  • 17
    • 0029074859 scopus 로고
    • Genetics of tumour necrosis factor a in autoimmune, infectious and neoplastic disease
    • Wilson, A. G., di Giovine, F. S., and Duff, G. W. Genetics of tumour necrosis factor a in autoimmune, infectious and neoplastic disease. J. Inflamm., 45: 1-12, 1995.
    • (1995) J. Inflamm. , vol.45 , pp. 1-12
    • Wilson, A.G.1    Di Giovine, F.S.2    Duff, G.W.3
  • 20
    • 0028985987 scopus 로고
    • EGF-mediated phosphorylation of extracellular signal-regulated kinases in osteoblastic cells
    • Zhang, W., Dziak, R. M., and Aletta, J. M. EGF-mediated phosphorylation of extracellular signal-regulated kinases in osteoblastic cells. J. Cell. Physiol., 162: 348-358, 1995.
    • (1995) J. Cell. Physiol. , vol.162 , pp. 348-358
    • Zhang, W.1    Dziak, R.M.2    Aletta, J.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.