Two regions of deletion in 9p23-24 in sporadic breast cancer

Cancer Research

Volumn 59, Issue 16, 1999, Pages 3941-3943

  An, Han Xiang ^a   Claas, Andreas ^a   Savelyeva, Larissa ^a   Seitz, Susanne ^b   Schlag, Peter ^b   Scherneck, Siegfried ^b   Schwab, Manfred ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ARTICLE; BREAST CANCER; CHROMOSOME 9P; CHROMOSOME REARRANGEMENT; GENE DELETION; GENE LOCATION; GENETIC ANALYSIS; HETEROZYGOSITY; HUMAN; HUMAN TISSUE; PATHOGENESIS; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

BREAST NEOPLASMS; CHROMOSOMES, HUMAN, PAIR 9; FEMALE; GENE FREQUENCY; GENOME, HUMAN; HUMANS; LOSS OF HETEROZYGOSITY; SEQUENCE DELETION;

EID: 0033566763     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Feuer, E. J. The lifetime risk of developing of breast cancer. J. Natl. Cancer Inst., 85: 892-897, 1993.
2. Biéche, I., and Lidereau, R. Genetic alterations in breast cancer. Genes Chromosomes Cancer, 14: 227-251, 1995.
3. Devilee, P., and Cornelisse, C. Somatic genetic changes in human breast cancer. Biochim. Biophys. Acta., 1198: 113-130, 1994.
4. Ford, D., Easton, D. F., Stratton, M., Narod, S., Goldgar, D., Devilee, P., Bishop, D. T., Weber, B., Lenoir, G., Chang-Claude, J., Sobol, H., Teare, M. D., Struewing, J., Arason, A., Scherneck, S., Peto, J., Rebbeck, T. R., Tonin, P., Neuhausen, S., Barkardottir, R., Eyfjord, J., Lynch, H., Ponder, B. A., Gayther, S. A., Zelada-Hedman, M., and The Breast Cancer Linkage Consortium. Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. Am. J. Hum. Genet., 62: 676-689, 1998.
5. Neuhausen, S. L., Godwin, A. K., Gershoni-Baruch, R., Schubert, E., Garber, J., Stoppa-Lyonnet, D., Olah, E., Csokay, B., Serova, O., Lalloo, F., Osorio, A., Stratton, M., Offit, K., Boyd, J., Caligo, M. A., Scott, R. J., Schofield, A., Teugels, E., Schwab, M., Cannon-Albright, L., Bishop, T., Easton, D., Benitez, J., King, M. C., and Goldgar, D. Haplotype and phenotype analysis of nine recurrent BRCA2 mutations in 111 families: results of an international study. Am. J. Hum. Genet., 62: 1381-1388, 1998.
6. Wilson, C. A., Ramos, L., Villasenor, M. R., Anders, K. H., Press, M. F., Clarke, K., Karlan, B., Chen, J. J., Scully, R., Livingston, D., Zuch, R. H., Kanter, M. H., Cohen, S., Calzone, F. J., and Slamon, D. J. Localization of human BRCA1 and its loss in high-grade, non-inherited breast carcinomas. Nat. Genet., 21: 236-240, 1999.
7. Futreal, P. A., Liu, Q., Shattuck-Eidens, D., Cochran, C., Harshman, K., Tavtigian, S., Bennett, L. M., Haugen-Strano, A., Swensen, J., and Miki, Y. BRCA1 mutations in primary breast and ovarian carcinomas. Science (Washington DC), 266: 120-122, 1994.
8. Lancaster, J. M., Wooster, R., Mangion, J., Phelan, C. M., Cochran, C., Gumbs, C., Seal, S., Barfoot, R., Collins, N., Bignell, G., Patel, S., Hamoudi, R., Larsson, C., Wiseman, R. W., Berchuck, A., Iglehart, J. D., Marks, J. R., Ashworth, A., Stratton, M. R., and Futreal, P. A. BRCA2 mutations in primary breast and ovarian cancers. Nat. Genet., 13: 238-240, 1996.
9. Miki, Y., Katagiri, T., Kasumi, F., Yoshimoto, T., and Nakamura, Y. Mutation analysis in the BRCA2 gene in primary breast cancers. Nat. Genet., 13: 245-247, 1996.
10. Czerniak, B., Chaturvedi, V., Li, L., Hodges, S., Johnston, D., Roy, J. Y., Luthra, R., Logothetis, C., Von Eschenbach, A. C., Grossman, H. B., Benedict, W. F., and Batsakis, J. G. Superimposed histologic and genetic mapping of chromosome 9 in progression of human urinary bladder neoplasia: implications for a genetic model of multistep urothelial carcinogenesis and early detection of urinary bladder cancer. Oncogene, 18: 1185-1196, 1999.
11. Simoneau, A. R., Spruck, C. H., III, Gonzalez-Zulueta, M., Gonzalgo, M. L., Chan, M. F., Tsai, Y. C., Dean, M., Steven, K., Horn, T., and Jones, P. A. Evidence for two tumor suppressor loci associated with proximal chromosome 9p to q and distal chromosome 9q in bladder cancer and the initial screening for GASI and PTC mutations. Cancer Res., 56: 5039-5043, 1996.
12. Keen, A. J., and Knowles, M. A. Definition of two regions of deletion on chromosome 9 in carcinoma of the bladder. Oncogene, 9: 2083-2088, 1994.
13. Kim, S. K., Ro, J. Y., Kemp, B. L., Lee, J. S., Kwon, T. J., Fong, K. M., Sekido, Y., Minna, J. D., Hong, W. K., and Mao, L. Identification of three distinct tumor suppressor loci on the short arm of chromosome 9 in small cell lung cancer. Cancer Res., 57: 400-403, 1997.
14. Wiest, J. S., Franklin, W. A. Otstot, J. T., Forbey, K., Varella-Garcia, M., Rao, K., Drabkin, H., Gemmill, R., Ahrent, S., Sidransky, D., Saccomanno, G., Fountain, J. W., and Anderson, M. W. Identification of a novel region of homozygous deletion on chromosome 9p in squamous cell carcinoma of the lung: the location of a putative tumor suppressor gene. Cancer Res., 57: 1-6, 1997.
15. Merlo, A., Gabrielson, E., Askin, F., and Sidransky, D. Frequent loss of chromosome 9 in human primary non-small cell lung cancer. Cancer Res., 54: 640-642, 1994.
16. Neville, E. M., Stewart, M., Myskow, M., Donnelly, R. J., and Field, J. K. Loss of heterozygosity at 9p23 defines a novel locus in non-small cell lung cancer. Oncogene, 11: 581-585, 1995.
17. Farrell, W. E., Simpson, D. J., Bicknell, J. E., Talbot, A. J., Bates, A. S., and Clayton, R. N. Chromosome 9p deletions in invasive and noninvasive nonfunctional pituitary adenomas: the deleted region involves markers outside of the MTS1 and MTS2 genes. Cancer Res., 57: 2703-2709, 1997.
18. Puig, S., Ruiz, A., Lazaro, C., Castel, T., Lynch, M., Palou, J., Vilalta, A., Weissenbach, J., Mascaro, J. M., and Estivill, X. Chromosome 9p deletions in cutaneous malignant melanoma tumors: the minimal deleted region involves markers outside the p16 (CDKN2) gene. Am. J. Hum. Genet., 57: 395-402, 1995.
19. Holland, E. A., Beaton, S. C., Edwards, B. G., Kefford, R. F., and Mann, G. J. Loss of heterozygosity and homozygous deletions on 9p21-22 in melanoma. Oncogene, 9: 1361-1365, 1994.
20. Tannin, L., Yin, J., Zhou, X., Suzuki, H., Jiang, H. Y., Rhyu, M. G., Abraham, J. M., Krasna, M. J., Cottrell, J., and Meltzer, S. J. Frequent loss of heterozygosity on chromosome 9 in adenocarcinoma and squamous cell carcinoma of the esophagus. Cancer Res., 54: 6094-6096, 1994.
21. Takita, J., Hayashi, Y., Kohno, T., Yamaguchi, N., Hanada, R., Yamamoto, K., and Yokota, J. Deletion map of chromosome 9 and p16 (CDKN2A) gene alterations in neuroblastoma. Cancer Res., 57: 907-912, 1997.
22. Savelyeva, L., Claas, A., Gier, S., Schlag, P., Finke, L., Mangion, J., Stratton, M. R., and Schwab, M. An interstitial tandem duplication of 9p23-24 coexists with a mutation in the BRCA2 gene in the germ line of three brothers with breast cancer. Cancer Res., 58: 863-866, 1998.
23. Savelyeva, L., Claas, A., An, H. X., Weber, R. G., Lichter, P., and Schwab, M. Retention of polysomy at 9p23-24 during karyotypic evolution in human breast cancer cell line COLO 824. Genes Chromosomes Cancer, 24: 87-93, 1999.
24. Eiriksdottir, G., Sigurdsson, A., Jonasson, J. G., Agnarsson, B. A., Sigurdsson, H., Gudmundsson, J., Bergthorsson, J. T., Barkardottir, R. B., Egilsson, V., and Ingvarsson, S. Loss of heterozygosity on chromosome 9 in human breast cancer: association with clinical variables and genetic changes at other chromosome regions. Int. J. Cancer, 64: 378-382, 1995.
25. Brenner, A. J., and Aldaz, C. M. Chromosome 9p allelic loss and p16/CDKN2 in breast cancer and evidence of p16 inactivation in immortal breast epithelial cells. Cancer Res., 55: 2892-2895, 1995.
26. An, H. X., Niederacher, D., Picard, F., van Roeyen, C., Bender, H. G., and Beckmann, M. W. Frequent allele loss on 9p21-22 defines a smallest common region in the vicinity of the CDKN2 gene in sporadic breast cancer. Genes Chromosomes Cancer, 17: 14-20, 1996.
27. Marsh, K. L., and Varley, J. M. Loss of heterozygosity at chromosome 9p in ductal carcinoma in situ and invasive carcinoma of the breast. Br. J. Cancer, 77: 1439-1447, 1998.
28. Cairns, P., Tokino, K., Eby, Y., and Sidransky, D. Homozygous deletions of 9p21 in primary human bladder tumors detected by comparative multiplex polymerase chain reaction. Cancer Res., 54: 1422-1424, 1994.
29. Pandis, N., Jin, Y., Gorunova, L., Petersson, C., Bardi, G., Idvall, I., Johansson, B., Ingvar, C., Mandahl, N., and Mitelman, F. Chromosome analysis of 97 primary breast carcinomas: identification of eight karyotypic subgroups. Genes Chromosomes Cancer, 12: 173-185, 1995.