Synthesis and characterization of complexes of p-isopropyl benzaldehyde and methyl 2-pyridyl ketone thiosemicarbazones with Zn(II) and Cd(II) metallic centers. Cytotoxic activity and induction of apoptosis in Pam-ras cells

Journal of Inorganic Biochemistry

Volumn 75, Issue 4, 1999, Pages 255-261

  Pérez, José M ^a   Matesanz, Ana I ^a   Martín Ambite, Alfonso ^a   Navarro, Paloma ^a   Alonso, Carlos ^a   Souza, Pilar ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

Apoptosis; Cytotoxic activity; Methyl 2 pyridyl ketone thiosemicarbazones; p Isopropyl benzaldehyde thiosemicarbazones; Pam ras cells

Indexed keywords

2 ACETYLPYRIDINE THIOSEMICARBAZONE; ANTINEOPLASTIC AGENT; CADMIUM; CISPLATIN; CUMINALDEHYDE; DNA; DNA FRAGMENT; METAL COMPLEX; ZINC;

ANIMAL CELL; APOPTOSIS; ARTICLE; CIRCULAR DICHROISM; CYTOTOXICITY; DNA BINDING; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; NONHUMAN; ONCOGENE H RAS; SYNTHESIS;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CADMIUM; CATTLE; CELLS, CULTURED; CISPLATIN; DNA; DNA FRAGMENTATION; GENES, RAS; HAPLORHINI; HELA CELLS; HUMANS; INHIBITORY CONCENTRATION 50; KERATINOCYTES; MICE; ORGANOMETALLIC COMPOUNDS; SPECTROPHOTOMETRY, INFRARED; SPECTROPHOTOMETRY, ULTRAVIOLET; THIOSEMICARBAZONES; THYMUS GLAND; ZINC;

ANIMALIA;

EID: 0033566189     PISSN: 01620134     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0162-0134(99)00096-3     Document Type: Article

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