Osteocalcin binds tightly to the γ-glutamylcarboxylase at a site distinct from that of the other known vitamin K-dependent proteins

Biochemical Journal

Volumn 341, Issue 2, 1999, Pages 265-269

  Houben, Roger J T J ^a   Jin, Dayun ^b   Stafford, Darrel W ^b   Proost, Paul ^c   Ebberink, Rob H M ^d   Vermeer, Cees ^a   Soute, Berry A M ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c UNIVERSITY OF LEUVEN   (Belgium)

^d Perkin Elmer Netherlands Ltd   (Netherlands)

Author keywords

Bone Gla protein; Phylloquinone; Post translational processing; carboxyglutamate

Indexed keywords

OSTEOCALCIN; PROTEIN PRECURSOR; RECOMBINANT ENZYME; VITAMIN K DEPENDENT CARBOXYLASE; VITAMIN K GROUP;

ARTICLE; BINDING KINETICS; BINDING SITE; CARBOXYLATION; CONTROLLED STUDY; INHIBITION KINETICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING;

EID: 0033565894     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3410265     Document Type: Article

References (31)

1. Hauschka, P. V., Haroon, Y., Buchthal, S. D. and Bell, R. G. (1986) Haemostasis 16, 273-287
2. Wolf, G. (1996) Nutr. Rev. 54, 332-333
3. Price, P. A. (1988) Annu. Rev. Nutr. 8, 565-583
4. Hauschka, P. V., Lian, J. B., Cole, D. E. and Gundberg, C. M. (1989) Physiol. Rev. 69, 990-1047
5. Furie, B. C. and Furie, B. (1997) Thromb. Haemost. 78, 595-598
6. Wu, S. M., Morris, D. P. and Stafford, D. W. (1991) Proc. Natl. Acad. Sci. U.S.A. 88, 2236-2240
7. Vermeer, C. (1990) Biochem. J. 266, 625-636
8. Fraser, J. D. and Price, P. A. (1988) J. Biol. Chem. 263, 11033-11036
9. Luo, G., Ducy, P., McKee, M. D., Pinero, G. J., Loyer, E., Behringer, R. R. and Karsenty, G. (1997) Nature (London) 385, 78-81
10. Nakano, T., Kawamoto, K., Kishino, J., Nomura, K., Higashino, K. and Arita, H. (1997) Biochem. J. 323, 387-392
11. Engelke, J. A., Hale, J. E., Suttie, J. W. and Price, P. A. (1991) Biochim. Biophys. Acta 1078, 31-34
12. Jorgensen, M. J., Cantor, A. B., Furie, B. C., Brown, C. L., Shoemaker, C. B. and Furie, B. (1987) Cell 48, 185-191
13. Ulrich, M. M., Furie, B., Jacobs, M. R., Vermeer, C. and Furie, B. C. (1988) J. Biol. Chem. 263, 9697-9702
14. Furie, B., Bouchard, B. A. and Furie, B. C. (1999) Blood 93, 1798-1808
15. Suttie, J. W., Lehrman, S. R., Geweke, L. O., Hageman, J. M. and Rich, D. H. (1979) Biochem. Biophys Res. Commun. 86, 500-507
16. Suttie, J. W. and Jackson, C. M. (1977) Physiol. Rev. 57, 1-70
17. Wu, S. M., Soute, B. A. M., Vermeer, C. and Stafford, D. W. (1990) J. Biol. Chem. 265, 13124-13129
18. Soute, B. A. M., Ulrich, M. M., Watson, A. D., Maddison, J. E., Ebberink, R. H. and Vermeer, C. (1992) Thromb. Haemost. 68, 521-525
19. Cheung, A., Engelke, J. A., Sanders, C. and Suttie, J. W. (1989) Arch. Biochem. Biophys. 274, 574-581
20. Benton, M. E., Price, P. A. and Suttie, J. W. (1995) Biochemistry 34, 9541-9551
21. Ulrich, M. M., Soute, B. A. M., de Boer van den Berg, M. A. and Vermeer, C. (1985) Biochim. Biophys. Acta 830, 105-108
22. Van Haarlem, L. J., Ulrich, M. M., Hemker, H. C., Soute, B. A. M. and Vermeer, C. (1987) Biochem. J. 245, 251-255
23. Stearns, D. J., Kurosawa, S., Sims, P. J., Esmon, N. L. and Esmon, C. T. (1988) J. Biol. Chem. 263, 826-832
24. Wu, S. M., Mutucumarana, V. P. and Stafford, D. W. (1997) Methods Enzymol. 282, 346-357
25. Wu, C.-R., Stevens, V. C., Tregear, G. W. and Wade, J. D. (1989) J. Chem. Soc. Perkin Trans. I, 81-87
26. Ramage, R., Green, J. and Ogunjobi, O. M. (1989) Tetrahedron Lett. 28, 2149-2152
27. Ogunjobi, O. and Ramage, R. (1990) Biochem. Soc. Trans. 18, 1322-1323
28. Chun, R., Glabe, C. G. and Fan, H. (1990) J. Virol. 64, 3074-3077
29. Knobloch, J. E. and Suttie, J. W. (1987) J. Biol. Chem. 262, 15334-15337
30. Price, P. A. and Williamson, M. K. (1985) J. Biol. Chem. 260, 14971-14975
31. Young, M. F., Kerr, J. M., Ibaraki, K., Heegaard, A. M. and Robey, P. G. (1992) Clin. Orthop. 281, 275-294