Divergence of binding, signaling, and biological responses to recombinant human hybrid IFN

Journal of Immunology

Volumn 163, Issue 2, 1999, Pages 854-860

  Hu, Renqiu ^a   Bekisz, Joseph ^a   Hayes, Mark ^a   Audet, Susette ^a   Beeler, Judy ^a   Petricoin, Emanuel ^a   Zoon, Kathryn ^a  

^a CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN HY 1; PROTEIN HY 2; PROTEIN HY 3; RECOMBINANT ALPHA INTERFERON; STAT1 PROTEIN; STAT2 PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CANCER CELL; CANCER THERAPY; CELL PROLIFERATION; ENZYME ACTIVATION; GENE INDUCTION; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION;

EID: 0033565299     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Hayes, M. P., and K. C. Zoon. 1994. Production and action of interferons: new insights into molecular mechanisms of gene regulation and expression. In Progress in Drug Research, Vol. 43. Ernst Jucker, ed. Birkhauser Verlag, Berlin, p. 239.
2. Weiss, K. 1998. Safety profile of interferon-α therapy. Semin. Oncol. 25 (Suppl. 1):9.
3. Streuli, M., A. Hall, W. Boll, W. E. Stewart, S. Nagata, and C. Weissmann. 1981. Target-cell specificity of two species of human interferon-α produced in E. coli and of hybrid molecules derived from them. Proc. Natl. Acad. Sci. USA 78:2848.
4. Horisberger, M. A., and S. DiMarco. 1995. Interferon-α hybrids. Pharmacol. Ther. 66:507.
5. Rehberg, E., B. Kelder, E. G. Hoal, and S. Pestka. 1982. Specific molecular activities of recombinant and hybrid leukocyte interferons. J. Biol. Chem. 257: 11497.
6. Meister, A., G. Uze, K. E. Morgensen, I. Gresser, M. G. Yovey, M. Gruetter, and F. Meyer. 1986. Biological activities and receptor binding of two human recombinant interferons and their hybrids. J. Gen. Virol. 67:1633.
7. Fidler, I. J., R. Heicappell, I. Saiki, M. G. Grutter, M. A. Horisberger, and J. Nuesch. 1987. Direct antiproliferative effects of recombinant human interfer-on-α B/D hybrids on human tumor cell lines. Cancer. Res. 47:2020.
8. Sperber, S. J., S. B. Hunger, B. Schwartz, and S. Pestka. 1993. Anti-rhinoviral activity of recombinant and hybrid species of interferon α. Antiviral Res. 22:121.
9. Mitsui, Y., T. Senda, T. Shimazu, S. Matsuda, and J. Utsumi. 1993. Structural, functional and evolutionary implications of the three-dimensional crystal structure of murine interferon-β. Pharmacol. Ther. 58:93.
10. Muller, U., U. Steinhoff, L. F. L. Reis, S. Hemmi, J. Pavlovic, R. M. Zinkernagel, and M. Aguet. 1994. Functional role of type I and type II interferons in antiviral defense. Science 264:1918.
11. Zav'Yalov, V. P., and G. A. Zav'yalov. 1997. Interferons α/β and their receptors: place in the hierarchy of cytokines. APMIS 105:161.
12. Zoon, K. C., D. Miller, J. Bekisz, D. ZurNedden, J. C. Enterline, N. Nguyen, and R. Hu. 1992. Purification and characterization of multiple components of human lymphoblastoid interferon-α. J. Biol. Chem. 267:15210.
13. Hu, R., Y. Gan, J. Liu, D. Miller, and K. C. Zoon. 1993. Evidence for multiple binding sites for several components of human lymphoblastoid interferon-α. J. Biol. Chem. 268:12591.
14. Hu, R., and K. C. Zoon. 1994. HuIFNA21 gene expression and properties of recombinant IFNA21. J. Interferon Res. 14:S98.
15. Korn, A. P., D. R. Rose, and E. N. Fish. 1994. Three-dimensional model of a human interferon-α consensus sequence. J. Interferon Res. 12:1.
16. Mitsui, Y. 1997. Elucidation of the basic three-dimensional structure of type I interferons and its functional and evolutionary implications. J. Interferon Cytokine Res. 17:319.
17. Saiki, R. K., and R. Higuchi. 1990. PCR Protocols: A Guide to Methods and Applications. Academic Press, New York, NY.
18. Sanger, F., S. Nicklen, and A. R. Coulson. 1977. DNA sequencing with chainterminating inhibitors. Proc. Natl. Acad. Sci. USA 74:5463.
19. Horton, R. M., H. D. Hunt, S. N. Ho, J. K. Pullen, and L. R. Pease. 1989. Engineering hybrid genes without the use of restriction enzymes. Gene 77:61.
20. 1997. The QIA expressionist: the high level expression and protein purification system. Qiagen, Santa Clarita, CA.
21. Janknecht, R., G. DeMartynoff, J. Lou, R. A. Hipskind, A. Nordhei, and H. G. Stunnenberg. 1991. Rapid and efficient purification of native, histidine-tagged protein expressed by recombinant vaccinia virus. Proc. Natl. Acad. Sci. USA 88:8972.
22. Petricoin, E. F., S. Ito, B. L. Williams, S. Audet, L. F. Stancato, A. Gamero, K. Clouse, P. Grimley, A. Weiss, J. Beeler, D. S. Finbloom, E. W. Shores, R. Abraham, A. C. Lamer. 1997. Antiproliferative action of interferon-α requires components of T-cell receptor signalling. Nature 390:629.
23. Lamer, A. C., M. David, G. M. Feldman, K. Igarashi, R. H. Hackett, D. S. Webb, S. M. Sweitzer, E. F. Petricoin III, and D. S. Finbloom. 1993. Tyrosine phosphorylation of DNA binding proteins by multiple cytokines. Science 261:1730.
24. Zoon, K. C., D. Zur Nedden, and H. Amheiter. 1982. Specific binding of human α interferon to a high affinity cell surface binding site on bovine kidney cells. J. Biol. Chem. 257:4695.
25. Grander, D., O. Sangfelt, and S. Erickson. 1997. How does interferon exert its cell growth inhibitory effect? Eur. J. Haematol. 59:129.
26. Walter, M. R. 1997. Three-dimensional models for interferon-α subtypes IFN-conl, IFN-α8 and IFN-α1 derived from the crystal structure of IFN-α2b. Semin. Oncol. 24:S52.
27. Viscomi, G. C. 1997. Structure-activity of type I interferons. Biotherapy 10:59.
28. Murgolo, N. J., W. T. Windsor, A. Hruza, P. Reichert, A. Tsarbopoulos, S. Baldwin, E. Huang, B. Pramanik, S. Ealick, and P. P. Trotta. 1993. A homology model of human interferon-α2. Proteins Struct. Funct. Genet. 17:62.
29. DiMarco, S., M. G. Grutter, J. P. Priestle, and M. A. Horisberger. 1994. Mutational analysis of the structure-function relationship in interferon-α. Biochem. Biophys. Res. Commun. 202:1445.
30. Fish, E. N. 1992. Definition of receptor binding domains in interferon-α. J. Interferon Res. 12:257.
31. Fish, E. N., K. Banerjee, and N. Stebbing. 1989. The role of three domains in the biological activity of human interferon-α. J. Interferon Res. 9:97.
32. Kontsek, P., L. Borecky, E. Kontsekova, I. Macikova, A. Kolcunova, M. Novak, and V. Krchnak. 1991. Mapping of two immunodominant structures on human interferon α2c and their role in binding to cells. Mol. Immunol. 28:1289.
33. Colamonici, O., and L. M. Pfeffer. 1991. Structure of the human interferon α receptor. Pharmacol. Ther. 52:227.