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Volumn 162, Issue 10, 1999, Pages 5805-5812

Costimulation reverses the defect in IL-2 but not effector cytokine production by T cells with impaired IκBα degradation

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; CD4 ANTIGEN; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR PROTEIN; INTERLEUKIN 2; INTERLEUKIN 4; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR AP 1;

EID: 0033563092     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (24)

References (66)
  • 1
    • 0025602793 scopus 로고
    • Extrathymic tolerance of mature T cells: Clonal elimination as a consequence of immunity
    • Webb, S., C. Morris, and J. Sprent. 1990. Extrathymic tolerance of mature T cells: clonal elimination as a consequence of immunity. Cell 63:1249.
    • (1990) Cell , vol.63 , pp. 1249
    • Webb, S.1    Morris, C.2    Sprent, J.3
  • 2
    • 0026434554 scopus 로고
    • Separation of IL-4 production from Th cell proliferation by an altered T cell receptor ligand
    • Evavold, B. D., and P. M. Allen. 1991. Separation of IL-4 production from Th cell proliferation by an altered T cell receptor ligand. Science 252:1308.
    • (1991) Science , vol.252 , pp. 1308
    • Evavold, B.D.1    Allen, P.M.2
  • 4
    • 0030200829 scopus 로고    scopus 로고
    • The roles of Fas/APO-1 (CD95) and TNF in antigen-induced programmed cell death in T cell receptor transgenic mice
    • Sytwu, H.-K., R. S. Liblau, and H. O. McDevitt. 1996. The roles of Fas/APO-1 (CD95) and TNF in antigen-induced programmed cell death in T cell receptor transgenic mice. Immunity 5:17.
    • (1996) Immunity , vol.5 , pp. 17
    • Sytwu, H.-K.1    Liblau, R.S.2    McDevitt, H.O.3
  • 5
    • 0030023574 scopus 로고    scopus 로고
    • Surface T cell Fas receptor/CD95 regulation, in vivo activation, and apoptosis: Activation-induced death can occur without Fas receptor
    • Tucek-Szabo, C. L., S. Andjelic, E. Lacy, K. B. Elkon, and J. Nikolic-Zugic. 1996. Surface T cell Fas receptor/CD95 regulation, in vivo activation, and apoptosis: activation-induced death can occur without Fas receptor. J. Immunol. 156:192.
    • (1996) J. Immunol. , vol.156 , pp. 192
    • Tucek-Szabo, C.L.1    Andjelic, S.2    Lacy, E.3    Elkon, K.B.4    Nikolic-Zugic, J.5
  • 6
    • 0029743824 scopus 로고    scopus 로고
    • Hierarchical control of lymphocyte survival
    • Boise, L. H., and C. B. Thompson. 1996. Hierarchical control of lymphocyte survival. Science 274:67.
    • (1996) Science , vol.274 , pp. 67
    • Boise, L.H.1    Thompson, C.B.2
  • 7
    • 0029933309 scopus 로고    scopus 로고
    • Altered peptide ligand-induced partial T cell activation
    • Sloan-Lancaster, J., and P. M. Allen. 1996. Altered peptide ligand-induced partial T cell activation. Annu. Rev. Immunol. 14:1.
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 1
    • Sloan-Lancaster, J.1    Allen, P.M.2
  • 8
    • 0029965138 scopus 로고    scopus 로고
    • Balancing immunity and tolerance: Deleting and tuning lymphocyte repertoires
    • Goodnow, C. G. 1996. Balancing immunity and tolerance: deleting and tuning lymphocyte repertoires. Proc. Natl. Acad. Sci. USA 93:2264.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 2264
    • Goodnow, C.G.1
  • 9
    • 0029444727 scopus 로고
    • Autoantigen-induced deletion of peripheral self-reactive T cells
    • Miller, J. F. A. P. 1995. Autoantigen-induced deletion of peripheral self-reactive T cells. Int. Rev. Immunol. 13:107.
    • (1995) Int. Rev. Immunol. , vol.13 , pp. 107
    • Miller, J.F.A.P.1
  • 10
    • 0024327899 scopus 로고
    • Clonal expansion vs. Functional clonal inactivation: A costimulatory signaling pathway determines the outcome of T cell antigen receptor occupancy
    • Mueller, D. L., M. K Jenkins, and R. H. Schwartz. 1989. Clonal expansion vs. functional clonal inactivation: a costimulatory signaling pathway determines the outcome of T cell antigen receptor occupancy. Annu. Rev. Immunol. 7:445.
    • (1989) Annu. Rev. Immunol. , vol.7 , pp. 445
    • Mueller, D.L.1    Jenkins, M.K.2    Schwartz, R.H.3
  • 11
    • 0023816040 scopus 로고
    • Antigen presenting function of class II MHC expressing pancreatic β cells
    • Markman, J., D. Lo, A. Naji, R. D. Palmiter, R. L. Brinster, and E. Heber-Katz. 1988. Antigen presenting function of class II MHC expressing pancreatic β cells. Nature 336:476.
    • (1988) Nature , vol.336 , pp. 476
    • Markman, J.1    Lo, D.2    Naji, A.3    Palmiter, R.D.4    Brinster, R.L.5    Heber-Katz, E.6
  • 12
    • 0028102655 scopus 로고
    • High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein-specific T cell receptor transgenic mice
    • Lafaille, J., K. Nagashima, M. Katsuki, and S. Tonegawa. 1994. High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein-specific T cell receptor transgenic mice. Cell 78:399.
    • (1994) Cell , vol.78 , pp. 399
    • Lafaille, J.1    Nagashima, K.2    Katsuki, M.3    Tonegawa, S.4
  • 16
    • 0026537347 scopus 로고
    • CD28-mediated signaling co-stimulates murine cells and prevents induction of anergy in T-cell clones
    • Harding, F. A., J. G. McArthur, J. A. Gross, D. H. Raulet, and J. P. Allison. 1992. CD28-mediated signaling co-stimulates murine cells and prevents induction of anergy in T-cell clones. Nature 356:607.
    • (1992) Nature , vol.356 , pp. 607
    • Harding, F.A.1    McArthur, J.G.2    Gross, J.A.3    Raulet, D.H.4    Allison, J.P.5
  • 17
    • 0030592564 scopus 로고    scopus 로고
    • Expansion or elimination of B cells in vivo: Dual roles for CD40- and Fas (CD95)-ligands modulated by the B cell antigen receptor
    • Rathmell, J. C., S. E. Townsend, J. C. Xu, R. A. Flavell, and C. C. Goodnow. 1996. Expansion or elimination of B cells in vivo: dual roles for CD40- and Fas (CD95)-ligands modulated by the B cell antigen receptor. Cell 87:319.
    • (1996) Cell , vol.87 , pp. 319
    • Rathmell, J.C.1    Townsend, S.E.2    Xu, J.C.3    Flavell, R.A.4    Goodnow, C.C.5
  • 19
    • 0031022715 scopus 로고    scopus 로고
    • Accessory molecule and costimulation requirements for CD4 T cell response
    • Croft, M., and C. Dubey. 1997. Accessory molecule and costimulation requirements for CD4 T cell response. Crit. Rev. Immunol. 17:89.
    • (1997) Crit. Rev. Immunol. , vol.17 , pp. 89
    • Croft, M.1    Dubey, C.2
  • 20
    • 0024548313 scopus 로고
    • Contingent genetic regulatory events in T lymphocyte activation
    • Crabtree, G. R. 1989. Contingent genetic regulatory events in T lymphocyte activation. Science 243:355.
    • (1989) Science , vol.243 , pp. 355
    • Crabtree, G.R.1
  • 21
    • 0028174061 scopus 로고
    • Function and activation of NF-κB in the immune system
    • Baeuerle, P. A., and T. Henkel. 1994. Function and activation of NF-κB in the immune system. Annu. Rev. Immunol. 12:141.
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 141
    • Baeuerle, P.A.1    Henkel, T.2
  • 22
    • 0028014460 scopus 로고
    • Signal transduction by lymphocyte antigen receptors
    • Weiss, A., and D. R. Littman. 1994. Signal transduction by lymphocyte antigen receptors. Cell 76:263.
    • (1994) Cell , vol.76 , pp. 263
    • Weiss, A.1    Littman, D.R.2
  • 23
    • 0030973579 scopus 로고    scopus 로고
    • Transcription factors of the NF-AT family: Regulation and function
    • Rao, A., C. Luo, and P. G. Hogan. 1997. Transcription factors of the NF-AT family: regulation and function. Annu. Rev. Immunol. 15:707.
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 707
    • Rao, A.1    Luo, C.2    Hogan, P.G.3
  • 29
    • 0030925372 scopus 로고    scopus 로고
    • Perturbation of the T lymphocyte lineage in transgenic mice expressing a constitutive repressor of NF-κB
    • Boothby, M., A. L. Mora, D. C. Scherer, J. A. Brockman, and D. W. Ballard. 1997. Perturbation of the T lymphocyte lineage in transgenic mice expressing a constitutive repressor of NF-κB. J. Exp. Med. 185:1897.
    • (1997) J. Exp. Med. , vol.185 , pp. 1897
    • Boothby, M.1    Mora, A.L.2    Scherer, D.C.3    Brockman, J.A.4    Ballard, D.W.5
  • 30
    • 0028986075 scopus 로고
    • Control of IκBα proteolysis by site-specific signal-induced phosphorylation
    • Brown, K., S. Gerstberger, L. Carlson, G. Franzoso, and U. Siebenlist. 1995. Control of IκBα proteolysis by site-specific signal-induced phosphorylation. Science 267:1485.
    • (1995) Science , vol.267 , pp. 1485
    • Brown, K.1    Gerstberger, S.2    Carlson, L.3    Franzoso, G.4    Siebenlist, U.5
  • 32
    • 0029977948 scopus 로고    scopus 로고
    • CD28 mediates a potent costimulatory signal for rapid degradation of IκBβ which is associated with accelerated activation of various NF-κB/Rel heterodimers
    • Harhaj, E. W., S. B. Maggirwar, L. Good, and S. C. Sun. 1996. CD28 mediates a potent costimulatory signal for rapid degradation of IκBβ which is associated with accelerated activation of various NF-κB/Rel heterodimers. Mol. Cell. Biol. 16:6736.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 6736
    • Harhaj, E.W.1    Maggirwar, S.B.2    Good, L.3    Sun, S.C.4
  • 33
    • 0030176384 scopus 로고    scopus 로고
    • Upstream-downstream: CD28 cosignaling pathways and T cell function
    • Rudd, C. E. 1996. Upstream-downstream: CD28 cosignaling pathways and T cell function. Immunity 4:527.
    • (1996) Immunity , vol.4 , pp. 527
    • Rudd, C.E.1
  • 35
    • 0030999057 scopus 로고    scopus 로고
    • NF-κB RelA-deficient lymphocytes: Normal development of T cell and B cells, impaired production of IgA and IgG1, and reduced proliferative responses
    • Doi, T. S., T. Takahashi, O. Taguchi, T. Azuma, and Y. Obata. 1997. NF-κB RelA-deficient lymphocytes: normal development of T cell and B cells, impaired production of IgA and IgG1, and reduced proliferative responses. J. Exp. Med. 185:953.
    • (1997) J. Exp. Med. , vol.185 , pp. 953
    • Doi, T.S.1    Takahashi, T.2    Taguchi, O.3    Azuma, T.4    Obata, Y.5
  • 36
    • 0031035635 scopus 로고    scopus 로고
    • Differential transcription directed by discrete γ interferon promoter elements in naive and memory (effector) CD4 cells and CD8 cells
    • Aune, T. M., L. A. Penix, M. R. Rincon, and R. A. Flavell. 1997. Differential transcription directed by discrete γ interferon promoter elements in naive and memory (effector) CD4 cells and CD8 cells. Mol. Cell. Biol. 17:199.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 199
    • Aune, T.M.1    Penix, L.A.2    Rincon, M.R.3    Flavell, R.A.4
  • 38
    • 0024380087 scopus 로고
    • Rapid detection of octamer binding proteins with mini-extracts prepared from small numbers of cells
    • Schreiber, E., P. Mathias, M. Muller, and W. Schaffner. 1989. Rapid detection of octamer binding proteins with mini-extracts prepared from small numbers of cells. Nucleic Acids Res. 17:6419.
    • (1989) Nucleic Acids Res. , vol.17 , pp. 6419
    • Schreiber, E.1    Mathias, P.2    Muller, M.3    Schaffner, W.4
  • 39
    • 0026550073 scopus 로고
    • Human T cell activation through the activation inducer molecule CD69 enhances the activity of transcription factor AP-1
    • Tugures, A., M. A. Alonso, F. Sanchez-Madrid, and M. O. De Landazuri. 1992. Human T cell activation through the activation inducer molecule CD69 enhances the activity of transcription factor AP-1. J. Immunol. 148:2300.
    • (1992) J. Immunol. , vol.148 , pp. 2300
    • Tugures, A.1    Alonso, M.A.2    Sanchez-Madrid, F.3    De Landazuri, M.O.4
  • 41
    • 0029000938 scopus 로고
    • RelA is a potent transcriptional activator of the CD28 response element within the interleukin 2 promoter
    • Lai, J.-H., G. Horvath, J. Subleski, J. Bruder, P. Ghosh, and T.-H. Tan. 1995. RelA is a potent transcriptional activator of the CD28 response element within the interleukin 2 promoter. Mol. Cell. Biol. 15:4260.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 4260
    • Lai, J.-H.1    Horvath, G.2    Subleski, J.3    Bruder, J.4    Ghosh, P.5    Tan, T.-H.6
  • 42
    • 0029150389 scopus 로고
    • Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression
    • Kontgen, F., R. J. Grumont, A. Strasser, D. Metcalf, R. Li, D. Tarlinton, and S. Gerondakis. (1995) Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression. Genes Dev. 9:1965.
    • (1995) Genes Dev. , vol.9 , pp. 1965
    • Kontgen, F.1    Grumont, R.J.2    Strasser, A.3    Metcalf, D.4    Li, R.5    Tarlinton, D.6    Gerondakis, S.7
  • 43
    • 0029582793 scopus 로고
    • Inhibition of NF-AT-dependent transcription by NF-κB: Implications for differentia gene expression by T helper cell subsets
    • Casarolo, V., S. N. Georas, Z. Song, I. D. Zubkoff, S. A. Abdulkadir, D. Thanos, and S. J. Ono. 1995. Inhibition of NF-AT-dependent transcription by NF-κB: implications for differentia] gene expression by T helper cell subsets. Proc. Natl. Acad. Sci. USA 92:11623.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 11623
    • Casarolo, V.1    Georas, S.N.2    Song, Z.3    Zubkoff, I.D.4    Abdulkadir, S.A.5    Thanos, D.6    Ono, S.J.7
  • 45
    • 0030890603 scopus 로고    scopus 로고
    • Mouse CD-1 specific NK1 T cells: Development, specificity, and function
    • Bendelac, A., M. N. Rivera, S.-H. Park, and J. H. Roark. 1997. Mouse CD-1 specific NK1 T cells: development, specificity, and function. Annu. Rev. Immunol. 15:535.
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 535
    • Bendelac, A.1    Rivera, M.N.2    Park, S.-H.3    Roark, J.H.4
  • 46
    • 0028019261 scopus 로고
    • Effect of CD28 signal transduction on c-Rel in human peripheral blood T cells
    • Bryan, R. G., Y. Li, J. H. Lai, M. Van, N. R. Rice, R. R. Rich, and T. H. Tan. 1994. Effect of CD28 signal transduction on c-Rel in human peripheral blood T cells. Mol. Cell. Biol. 14:7933.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 7933
    • Bryan, R.G.1    Li, Y.2    Lai, J.H.3    Van, M.4    Rice, N.R.5    Rich, R.R.6    Tan, T.H.7
  • 47
    • 0030899121 scopus 로고    scopus 로고
    • IκB epsilon, a novel member of the IκB family, controls RelA and c-Rel NF-κB activity
    • Whiteside, S. T., J.-C. Epinat, N. R. Rice, and A. Israël. 1997. IκB epsilon, a novel member of the IκB family, controls RelA and c-Rel NF-κB activity. EMBO J. 16:1413.
    • (1997) EMBO J. , vol.16 , pp. 1413
    • Whiteside, S.T.1    Epinat, J.-C.2    Rice, N.R.3    Israël, A.4
  • 48
    • 0029814276 scopus 로고    scopus 로고
    • Role of unphosphorylated, newly synthesized IκBβ in persistent activation of NF-κB
    • Suyang, H., R. Phillips, I. Douglas, and S. Ghosh. 1996. Role of unphosphorylated, newly synthesized IκBβ in persistent activation of NF-κB. Mol. Cell. Biol. 16:5444.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 5444
    • Suyang, H.1    Phillips, R.2    Douglas, I.3    Ghosh, S.4
  • 49
    • 0030611782 scopus 로고    scopus 로고
    • Regulation of IκBβ in WEHI 231 mature B cells
    • Phillips, R. J., and S. Ghosh. 1997. Regulation of IκBβ in WEHI 231 mature B cells. Mol. Cell. Biol. 17:4390.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 4390
    • Phillips, R.J.1    Ghosh, S.2
  • 50
    • 0030584924 scopus 로고    scopus 로고
    • Costimulation of IL-4 production by mouse B7-1 and B7-2 molecules
    • Natesan, M., Z. Razi-Wolf, and H. Reiser. 1996. Costimulation of IL-4 production by mouse B7-1 and B7-2 molecules. J. Immunol. 156:2783.
    • (1996) J. Immunol. , vol.156 , pp. 2783
    • Natesan, M.1    Razi-Wolf, Z.2    Reiser, H.3
  • 52
    • 0029052324 scopus 로고
    • Negative transcriptional regulation of the interferon-γ promoter by glucocorticoids and dominant negative mutants of c-Jun
    • Cipitelli, M., A. Sica, V. Viggiano, J. Ye, P. Ghosh, M. J. Birrer, and H. A. Young. 1995. Negative transcriptional regulation of the interferon-γ promoter by glucocorticoids and dominant negative mutants of c-Jun. J. Biol. Chem. 270:12548.
    • (1995) J. Biol. Chem. , vol.270 , pp. 12548
    • Cipitelli, M.1    Sica, A.2    Viggiano, V.3    Ye, J.4    Ghosh, P.5    Birrer, M.J.6    Young, H.A.7
  • 53
    • 0023611441 scopus 로고
    • Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements
    • Lee, W., P. Mitchell, and R. Tjian. 1987. Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements. Cell 49:741.
    • (1987) Cell , vol.49 , pp. 741
    • Lee, W.1    Mitchell, P.2    Tjian, R.3
  • 55
    • 3643072843 scopus 로고    scopus 로고
    • Regulation of the activity of IFN-γ promoter elements during T helper cell differentiation
    • Zhang, F., D. Z. Wang, M. Boothby, L. A. Penix, R. A. Flavell, and T. M. Aune. 1998. Regulation of the activity of IFN-γ promoter elements during T helper cell differentiation. J. Immunol. 161:6105.
    • (1998) J. Immunol. , vol.161 , pp. 6105
    • Zhang, F.1    Wang, D.Z.2    Boothby, M.3    Penix, L.A.4    Flavell, R.A.5    Aune, T.M.6
  • 56
    • 0028902752 scopus 로고
    • ζ phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists
    • Madrenas, J., R. L. Wange, J. L. Wang, N. Isakov, L. E. Samelson, and R. N. Germain. 1995. ζ Phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists. Science 267:515.
    • (1995) Science , vol.267 , pp. 515
    • Madrenas, J.1    Wange, R.L.2    Wang, J.L.3    Isakov, N.4    Samelson, L.E.5    Germain, R.N.6
  • 57
    • 0027967385 scopus 로고
    • Partial T cell signaling altered phospho-ζ and lack of ZAP 70 recruitment an APL-induced T cell anergy
    • Sloan-Lancaster, J., A. S. Shaw, J. B. Rothbard, and P.M. Allen. 1994. Partial T cell signaling altered phospho-ζ and lack of ZAP 70 recruitment an APL-induced T cell anergy. Cell 79:913.
    • (1994) Cell , vol.79 , pp. 913
    • Sloan-Lancaster, J.1    Shaw, A.S.2    Rothbard, J.B.3    Allen, P.M.4
  • 58
    • 0028859281 scopus 로고
    • Selective requirement for MAP kinase activation in thymocyte differentiation
    • Alberola-Ila, J., K. A. Forbush, R. Seger, E. G. Krebs, and R. Perlmutter. 1995. Selective requirement for MAP kinase activation in thymocyte differentiation. Nature 373:620.
    • (1995) Nature , vol.373 , pp. 620
    • Alberola-Ila, J.1    Forbush, K.A.2    Seger, R.3    Krebs, E.G.4    Perlmutter, R.5
  • 59
    • 0030602798 scopus 로고    scopus 로고
    • The MAP kinase pathway controls differentiation from double-negative to double-positive thymocyte
    • Crompton, T., K. C. Gilmour, and M. J. Owen. 1996. The MAP kinase pathway controls differentiation from double-negative to double-positive thymocyte. Cell 86:243.
    • (1996) Cell , vol.86 , pp. 243
    • Crompton, T.1    Gilmour, K.C.2    Owen, M.J.3
  • 61
    • 0028292001 scopus 로고
    • Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase
    • Elder, M. E., D. Lin, J. Clever, A. C. Chan, T. J. Hope, A. Weiss, and T. G. Parslow. 1994. Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase. Science 264:1596.
    • (1994) Science , vol.264 , pp. 1596
    • Elder, M.E.1    Lin, D.2    Clever, J.3    Chan, A.C.4    Hope, T.J.5    Weiss, A.6    Parslow, T.G.7
  • 62
    • 0028409131 scopus 로고
    • Generation of normal T and B lymphocytes by c-Jun-deficient embryonic stem cells
    • Chen, J., V. Stewart, G. Spyrou, F. Hilberg, E. F. Wagner, and F. W. Alt. 1994. Generation of normal T and B lymphocytes by c-Jun-deficient embryonic stem cells. Immunity 1:65.
    • (1994) Immunity , vol.1 , pp. 65
    • Chen, J.1    Stewart, V.2    Spyrou, G.3    Hilberg, F.4    Wagner, E.F.5    Alt, F.W.6
  • 64
    • 0030298294 scopus 로고    scopus 로고
    • Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death
    • Liu, Z.-g., H. Hsu, D. V. Goeddel, and M. Karin. 1996. Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death. Cell 87:565.
    • (1996) Cell , vol.87 , pp. 565
    • Liu, Z.-G.1    Hsu, H.2    Goeddel, D.V.3    Karin, M.4
  • 65
    • 0029826970 scopus 로고    scopus 로고
    • c-Rel regulation of IL-2 gene expression may be mediated through activation of AP-1
    • Shapiro, V. S., M. N. Mollenauet, W. C. Greene, and A. Weiss. 1996. c-Rel regulation of IL-2 gene expression may be mediated through activation of AP-1. J. Exp. Med. 184:1663.
    • (1996) J. Exp. Med. , vol.184 , pp. 1663
    • Shapiro, V.S.1    Mollenauet, M.N.2    Greene, W.C.3    Weiss, A.4
  • 66
    • 0031285250 scopus 로고    scopus 로고
    • Activation of the IκBα kinase complex by MEKK1, a kinase of the JNK pathway
    • Lee, F. S., J. Hagler, Z. T. Chen, and T. Maniatis. 1997. Activation of the IκBα kinase complex by MEKK1, a kinase of the JNK pathway. Cell 88:213.
    • (1997) Cell , vol.88 , pp. 213
    • Lee, F.S.1    Hagler, J.2    Chen, Z.T.3    Maniatis, T.4


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