Regional metabolic changes in the pedunculopontine nucleus of unilateral 6-hydroxydopamine Parkinson's model rats

Brain Research

Volumn 828, Issue 1-2, 1999, Pages 12-19

  Carlson, Jonathan D ^a   Pearlstein, Robert D ^b   Buchholz, John ^a   Iacono, Robert P ^c   Maeda, George ^a  

^a LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c LOMA LINDA UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

2 Deoxyglucose autoradiography; 6 OHDA; Cerebral metabolism; Parkinson's disease; Pedunculopontine nucleus

Indexed keywords

CATECHOLAMINE; DEOXYGLUCOSE; GLUCOSE; OXIDOPAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BASAL GANGLION; BRAIN METABOLISM; CONTROLLED STUDY; DISEASE ASSOCIATION; GLOBUS PALLIDUS; GLUCOSE METABOLISM; METABOLIC ACTIVATION; METABOLIC RATE; MOTOR CORTEX; NERVE DEGENERATION; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; PARKINSON DISEASE; PATHOGENESIS; PRIORITY JOURNAL; RAT; SENSORY CORTEX; SUBSTANTIA NIGRA; SUBTHALAMIC NUCLEUS; TEGMENTUM;

3,4-DIHYDROXYPHENYLACETIC ACID; ANIMALS; ANTIMETABOLITES; BASAL GANGLIA DISEASES; CEREBRAL CORTEX; DEOXYGLUCOSE; DISEASE MODELS, ANIMAL; DOPAMINE; ENERGY METABOLISM; GLUCOSE; MALE; OXIDOPAMINE; PARKINSON DISEASE, SECONDARY; PONS; RATS; RATS, SPRAGUE-DAWLEY; SYMPATHOLYTICS;

EID: 0033562467     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(99)01268-8     Document Type: Article

References (50)

1. M.S. Aldrich, Medical disorders: Parkinsonism, in: H.M. Kryger, T. Roth, W.C. Dement (Eds.), Principles and Practice of Sleep Medicine, W.B. Saunders, Philadelphia, 1989, pp. 783-789.
2. Blaha C.D., Allen L.F., Das S., Inglis W.L., Latimer M.P., Vincent S.R., Winn P. Modulation of dopamine efflux in the nucleus accumbens after cholinergic stimulation of the ventral tegmental area in intact, pedunculopontine tegmental nucleus-lesioned, and lateraldorsal tegmental nucleus-lesioned rats. J. Neurosci. 16(2):1996;714-722.
3. Blaha C.D., Winn P. Modulation of dopamine efflux in the striatum following cholinergic stimulation of the substantia nigra in intact and pedunculopontine tegemental nucleus-lesioned rats. J. Neurosci. 13(3):1993;1035-1044.
4. Brudzynski S.M., Wu M., Mogenson G.J. Modulation of locomotor activity induced by injections of carbachol into the tegmental pedunculopontine nucleus and adjacent areas in the rat. Brain Res. 451:1988;119-125.
5. Buchholz J., Tsai H., Foucart S., Duckles S.P. Advancing age alters intracellular calcium buffering in rat adrenergic nerves. Neurobiol. Aging. 16:1996;885-892.
6. Burbaud P., Gross C., Benazzouz A., Coussemacq M., Bioulac B. Reduction of apomorphine-induced rotational behaviour by subthalamic lesion in 6-OHDA lesioned rats is associated with a normalization of firing rate and discharge pattern of pars reticulata neurons. Exp. Brain Res. 105:1995;48-58.
7. Carman L.S., Gage F.H., Shults C.W. Partial lesion of the substantia nigra: relation between extent of lesion and rotational behavior. Brain Res. 553:1991;275-283.
8. Dunbar J.S., Hitchcock K., Latimer M., Rugg E.L., Ward N., Winn P. Excitotoxic lesions of the peduculopontine tegmental nucleus of the rat: II. Examination of eating and drinking, rotation, and reaching and grasping following unilateral ibotenate or quinolinate lesions. Brain Res. 589:1992;194-206.
9. Engber T.M., Susel Z., Kuo S., Chase T.N. Chronic levodopa treatment alters basal dopamine agonist-stimulated cerebral glucose utilization. J. Neurosci. 10(12):1990;3889-3895.
10. Factor S.A., McAlarney T., Sanchez-Ramos J., Weiner W.J. Sleep disorders and sleep effect in Parkinson's disease. Mov. Disord. 5(4):1990;280-285.
11. Garcia-Rill E. The basal ganglia and the locomotor regions. Brain Res. Rev. 11:1986;47-63.
12. Garcia-Rill E. The pedunculopontine nucleus. Prog. Neurobiol. 36:1991;363-389.
13. Garcia-Rill E., Skinner R.D. The mesencephalic locomotor region: I. Activation of a medullary projection site. Brain Res. 411:1987;1-12.
14. Garcia-Rill E., Skinner R.D. Modulation of rhythmic function in the posterior midbrain. Neuroscience. 27:1988;639-654.
15. Garcia-Rill E., Skinner R.D., Fitzgerald J.A. Activity in the mesencephalic locomotor region during locomotion. Exp. Neurol. 82:1983;609-622.
16. Granata A.R., Kitai S.T. Intracellular analysis of excitatory subthalamic inputs to the pedunculopontine neurons. Brain Res. 488:1989;57-72.
17. Guela C., Schatz R., Mesulam M.M. Differential localization of NADPH-diaphorase and calbindin-D28k within the cholinergic neurons of the basal forebrain, striatum and brainstem in the rat, monkey, baboon and human. Neuroscience. 54:1993;461-476.
18. Hassani I.K., Mouroux M., Feger J. Increased subthalamic neuronal activity after nigral dopaminergic lesion independent of disinhibition via the globus pallidus. Neuroscience. 72:1996;105-115.
19. Hirsch E.C., Graybiel A.N., Duyckaerts C., Javoy-Agid F. Neuronal loss in the pedunculopontine tegmental nucleus in Parkinson's disease and in progressive supranuclear palsy. Proc. Natl. Acad. Sci. USA. 84:1987;5976-5980.
20. Iacono R.P., Shima F., Lonser R.R., Kuniyoshi S., Maeda G., Yamada S. The results, indications, and physiology of posteroventral pallidotomy for patients with Parkinsons's disease. Neurosurgery. 36:1995;1118-1127.
21. Inglis W.L., Winn P. The pedunculopontine tegmental nucleus: where the striatum meets the reticular formation. Prog. Neurobiol. 47:1995;1-29.
22. Jackson A., Crossman A.R. Nucleus tegmenti pedunculopontinus: efferent connections with special reference to the basal ganglia, studied in the rat by anterograde and retrograde transport of horseradish peroxidase. Neuroscience. 10:1983;725-765.
23. Kang Y., Kitai S.T. Electrophysiological properties of pedunculopontine neurons and their postsynaptic responses following stimulation of substantia nigra reticulata. Brain Res. 535:1990;79-95.
24. 14C] 2-deoxy-D-glucose incorporation into neostriatum and related structures in response to dopamine neuron damage and apomorphine replacement Brain Res. 197:1980;167-183.
25. Kreiss D.S., Mastropietro C.W., Rawji S.S., Walters J.R. The response of subthalamic nucleus neurons to dopamine receptor stimulation in a rodent model of Parkinson's disease. J. Neurosci. 17(17):1997;6807-6819.
26. Lawrence D.G., Kuypers H.G.J.M. The functional organization of the motor system in the monkey: I. the effects of bilateral pyramidal lesions. Brain. 91:1968;1-14.
27. MacLeod N.K., Ryman A., Arbuthnott G.W. Electrophysiological properties of nigrothalamic neurons after 6-hydroxydopamine lesions in the rat. Neuroscience. 38(2):1990;447-456.
28. Milner K.L., Mogenson G.J. Electrical and chemical activation of the mesencephalic and subthalamic locomotor regions in freely moving rats. Brain Res. 452:1988;273-285.
29. Mitchell I.J., Boyce S., Sambrook M.A., Crossman A.R. A 2-deoxyglucose study of the effects of dopamine agonists on the Parkinsonian primate brain. Brain. 115:1992;809-824.
30. Mitchell I.J., Clarke C.E., Boyce S., Robertson R.G., Peggs D., Sambrook M.A., Crossman A.R. Neural mechanisms underlying parkinsonian symptoms based upon regional uptake of 2-deoxyglucose in monkeys exposed to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Neuroscience. 32:1989;213-226.
31. Mohamed A.S., Iacono R.P., Yamada S. Normalization of middle latency auditory P1 potential following posterior ansa-pallidotomy in idiopathic Parkinson's disease. Neurol. Res. 18:1996;516-520.
32. S. Mori, Neurophysiology of locomotion: recent advances in the study of locomotion, in: J.C. Masdeu, L. Sudarsky, L. Solfson (Eds.), Gait Disorders of Aging. Falls and Therapeutic Strategies, Lippincott Raven, Philadelphia, 1997, pp. 55-78.
33. Mori S., Iwakiri H., Homma Y., Yokoyama T., Matsuyama K. Neuroanatomical and neurophysiological basis of postural control. Adv. Neurol. 67:1995;289-303.
34. Nakao N., Ogura M., Nakai K., Itakura T. Intrastriatal mesencaphalic grafts affect neuronal activity in basal ganglia and their target structures in a rat model of Parkinson's disease. J. Neurosci. 18:1998;1806-1817.
35. Palombo E., Porrino L.J., Bakiewicz K.S., Crane A.M., Sokoloff L., Kopin I.J. Local cerebral glucose utilization in monkeys with hemiparkinsonism induced by intracarotid infusion of the neurotoxin MPTP. J. Neuroscience. 10(3):1990;860-869.
36. Pare D., Dossi C., Datta S., Steriade M. Brainstem genesis of reserpine-induced ponto-geniculo-occipital waves: an electrophysiological and morphological investigation. Exp. Brain Res. 81:1990;533-544.
37. Perese D.A., Ulman J., Viola J., Ewing S.E., Bankiewiz K.S. A 6-hydroxydopamine-induced selective parkinsonian rat model. Brain Res. 494:1989;285-293.
38. Rye D.B., Saper C.B., Lee H.J., Wainer B.H. Pedunculopontine tegmental nucleus of the rat: cytoarchitecture, cytochemistry, and some extrapyramidal connections of the mesopontine tegmentum. J. Comp. Neurol. 259:1987;483-528.
39. Scarnati E., Florio T. The pedunculopontine nucleus and related structures functional organization. Adv. Neurol. 74:1997;97-110.
40. Scarnati E., Proia A., Loreto D., Pacitti C. The reciprocal electrophysiological influence between the nucleus tegmenti peduncuolpontinus and the substantia nigra in normal and decorticated rats. Brain Res. 423:1987;116-124.
41. Shima F., Sakato S., Sun J., Kato M., Fukui M., Iacono R.P. The role of the descending pallido-reticular pathway in movement disorders. Monogr. Neural Sci. 14:1995;197-207.
42. J.M. Siegel, Brainstem mechanisms generating REM sleep, in: M.H. Kryger, T. Roth, W.C. Dement (Eds.), Principles and Practice of Sleep Medicine, Saunders, Philadelphia, 1994, pp. 125-144.
43. Sokoloff L., Reivich M., Kennedy C., Des Rosiers M.H., Patlak C.S., Pettigrew K.D., Sakurada O., Shinohara M. The [14C]deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat. J. Neurochem. 28:1977;897-916.
44. Spann B.M., Grofova I. Origin of ascending and spinal pathways from the nucleus tegmenti pedunculopontinus in the rat. J. Comp. Neurol. 283:1989;13-27.
45. Steriade M., Datta S., Pare D., Dossi R.C. Neuronal activities in brain-stem cholinergic nuclei related to tonic activation processes in thalamocortical systems. J. Neurosci. 10(8):1990;2541-2559.
46. Steriade M., Pare D., Datta S., Oakson G., Dossi R.C. Different cellular types in mesopontine cholinergic nuclei related to ponto-geniculo-occipital waves. J. Neurosci. 10(8):1990;2560-2579.
47. Teo C., Rasco L., Al-Mefty K., Skinner R.D., Boop F.A., Garcia-Rill E. Decreased habituation of midlatency auditory evoked responses in Parkinson's disease. Mov. Disord. 12:1997;655-664.
48. Trugman J.M., James C.L., Wooten G.F. D1/D2 dopamine receptor stimulation by L-dopa. Brain. 114:1991;1429-1440.
49. Trugman J.M., Wooten G.F. Selective D1 and D2 dopamine agonists differentially alter basal ganglia glucose utilization in rats with unilateral 6-hydroxydopamine substantia nigra lesions. J. Neurosci. 7(9):1987;2927-2935.
50. Weick B.G., Walters J.R. Effects of D1 and D2 receptor stimulation on the activity of substantia nigra pars reticulata neurons in 6-hydroxydopamine lesioned rats: D1/D2 coactivation induces potentiated responses. Brain Res. 405:1987;234-236.