Interferon-γ prevents apoptosis in Epstein-Barr virus-infected natural killer cell leukemia in an autocrine fashion

Blood

Volumn 93, Issue 10, 1999, Pages 3494-3504

  Mizuno, Shin Ichi ^b   Akashi, Koichi ^a   Ohshima, Koichi ^b   Iwasaki, Hiromi ^b   Miyamoto, Toshihiro ^b   Uchida, Naoyuki ^b   Shibuya, Tsunefumi ^b   Harada, Mine ^b   Kikuchi, Masahiro ^b   Niho, Yoshiyuki ^b  

^a STANFORD UNIVERSITY   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON;

APOPTOSIS; ARTICLE; AUTOCRINE EFFECT; CELL CLONE; CELL SURVIVAL; DISEASE COURSE; EPSTEIN BARR VIRUS; HUMAN; HUMAN TISSUE; NATURAL KILLER CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; T CELL LEUKEMIA;

EID: 0033562373     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v93.10.3494.410k14_3494_3504     Document Type: Article

References (53)

1. Loughran TP Jr: Clonal diseases of large granular lymphocytes. Blood 82:1, 1993
2. Jaffe ES: Classification of natural killer (NK) cell and NK-like T-cell malignancies (editorial). Blood 87:1207, 1996
3. Oshimi K, Yamada O, Kaneko T, Nishinarita S, Iizuka Y, Urabe A, Inamori T, Asano S, Takahashi S, Hattori M, Naohara T, Ohira Y, Togawa A, Masuda Y, Okubo Y, Furasawa S, Sakamoto S, Omine M, Mori M, Tatsumi E, Mizoguchi H: Laboratory findings and clinical courses of 33 patients with granular lymphocyte-proliferative disorders. Leukemia 7:782, 1993
4. Imamura N, Kusunoki Y, Kawa-Ha K, Yumura K, Hara J, Oda K, Abe K, Dohy H, Inada T, Kajihara H, Kuramoto A: Aggressive natural killer cell leukaemia/lymphoma: Report of four cases and review of the literature. Possible existence of a new clinical entity originating from the third lineage of lymphoid cells. Br J Haematol 75:49, 1990
5. - lymphoproliferative disease of granular lymphocytes. Blood 81:2363, 1993
6. Tefferi A, Li CY, Witzig TE, Dhodapkar MV, Okuno SH, Phyliky RL: Chronic natural killer cell lymphocytosis: A descriptive clinical study. Blood 84:2721, 1994
7. Kawa-Ha K, Ishihara S, Ninomiya T, Yumura-Yagi K, Hara J, Murayama F, Tawa A, Hirai K: CD3-negative lymphoproliferative disease of granular lymphocytes containing Epstein-Barr viral DNA. J Clin Invest 84:51, 1989
8. Hart DN, Baker BW, Inglis MJ, Nimmo JC, Starling GC, Deacon E, Rowe M, Beard ME: Epstein-Barr viral DNA in acute large granular lymphocyte (natural killer) leukemic cells. Blood 79:2116, 1992
9. Hammerschmidt W, Sugden B: Genetic analysis of immortalizing functions of Epstein-Barr virus in human B lymphocytes. Nature 340:393, 1989
10. Abbot SD, Rowe M, Cadwallader K, Ricksten A, Gordon J, Wang F, Rymo L, Rickinson AB: Epstein-Barr virus nuclear antigen 2 induces expression of the virus-encoded latent membrane protein. J Virol 64:2126, 1990
11. Hockenbery D, Nunez G, Milliman C, Schreiber RD, Korsmeyer SJ: Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348:334, 1990
12. Henderson S, Rowe M, Gregory C, Croom-Carter D, Wang F, Longnecker R, Kieff E, Rickinson A: Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death. Cell 65:1107, 1991
13. Wilson JB, Bell JL, Levine AJ: Expression of Epstein-Barr virus nuclear antigen-1 induces B cell neoplasia in transgenic mice. EMBO J 15:3117, 1996
14. Ohshima K, Kikuchi M, Mizuno S, Akashi K, Moriyama K, Yoneda S, Takeshita M, Shibata T: Hepatosinusoidal leukaemia/ lymphoma consisting of Epstein-Barr virus-containing natural killer cell leukaemia/lymphoma and T-cell lymphoma; mimicking malignant histiocytosis. Hematol Oncol 13:83, 1995
15. Kobayashi Y, Uehara S, Inamori K, Shirato R, Ozawa K, Sklar J, Asano S: Hemophagocytosis as a para-neoplastic syndrome in NK cell leukemia. Int J Hematol 64:135, 1996
16. Imashuku S, Hibi S, Morinaga S, Takagi K, Chen J, Mugishima H, Ishii T, Sako M, Arakawa H, Kato M: Haemophagocytic lymphohistiocytosis in association with granular lymphocyte proliferative disorders in early childhood: Characteristic bone marrow morphology. Br J Haematol 96:708, 1997
17. Henter JI, Elinder G, Soder O, Hansson M, Andersson B, Andersson U: Hypercytokinemia in familial hemophagocytic lymphohistiocytosis. Blood 78:2918, 1991
18. Imashuku S, Hibi S, Fujiwara F, Ikushima S, Todo S: Haemophagocytic lymphohistiocytosis, interferon-gamma-naemia and Epstein-Barr virus involvement. Br J Haematol 88:656, 1994
19. Akashi K, Hayashi S, Gondo H, Mizuno S, Harada M, Tamura K, Yamasaki K, Shibuya T, Uike N, Okamura T, Miyamoto T, Niho Y: Involvement of interferon-gamma and macrophage colony-stimulating factor in pathogenesis of haemophagocytic lymphohistiocytosis in adults. Br J Haematol 87:243, 1994
20. Kawaguchi H, Miyashita T, Herbst H, Niedobitek G, Asada M, Tsuchida M, Hanada R, Kinoshita A, Sakurai M, Kobayashi N, Mizutani S: Epstein-Barr virus-infected T lymphocytes in Epstein-Barr virus-associated hemophagocytic syndrome. J Clin Invest 92:1444, 1993
21. Lay JD, Tsao CJ, Chen JY, Kadin ME, Su IJ: Upregulation of tumor necrosis factor-alpha gene by Epstein-Barr virus and activation of macrophages in Epstein-Barr virus-infected T cells in the pathogenesis of hemophagocytic syndrome. J Clin Invest 100:1969, 1997
22. Carson WE, Ross ME, Baiocchi RA, Marien MJ, Boiani N, Grabstein K, Caligiuri MA: Endogenous production of interleukin 15 by activated human monocytes is critical for optimal production of interferon-gamma by natural killer cells in vitro. J Clin Invest 96:2578, 1995
23. Ross ME, Caligiuri MA: Cytokine-induced apoptosis of human natural killer cells identifies a novel mechanism to regulate the innate immune response. Blood 89:910, 1997
24. Jewett A, Cavalcanti M, Bonavida B: Pivotal role of endogenous TNF-alpha in the induction of functional inactivation and apoptosis in NK cells. J Immunol 159:4815, 1997
25. Henter JI, Elinder G, Ost A: Diagnostic guidelines for hemophagocytic lymphohistiocytosis. The FHL Study Group of the Histiocyte Society. Semin Oncol 18:29, 1991
26. Akashi K, Kondo M, von Freeden-Jeffry U, Murray R, Weissman IL: Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice. Cell 89:1033, 1997
27. Hsu YT, Wolter KG, Youle RJ: Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis. Proc Natl Acad Sci USA 94:3668, 1997
28. Buschle M, Campana D, Carding SR, Richard C, Hoffbrand AV, Brenner MK: Interferon gamma inhibits apoptotic cell death in B cell chronic lymphocytic leukemia. J Exp Med 177:213, 1993
29. Raab-Traub N, Flynn K: The structure of the termini of the Epstein-Barr virus as a marker of clonal cellular proliferation. Cell 47:883, 1986
30. Chang KL, Chen YY, Shibata D, Weiss LM: Description of an in situ hybridization methodology for detection of Epstein-Barr virus RNA in paraffin-embedded tissues, with a survey of normal and neoplastic tissues. Diagn Mol Pathol 1:246, 1992
31. Mosmann T: Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods 65:55, 1983
32. Smith CA, Williams GT, Kingston R, Jenkinson EJ, Owen JJ: Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures. Nature 337:181, 1989
33. - blasts from acute myelogenous leukemia. Blood 78:197, 1991
34. Carson WE, Fehniger TA, Haldar S, Eckhert K, Lindemann MJ, Lai CF, Croce CM, Baumann H, Caligiuri MA: A potential role for interleukin-15 in the regulation of human natural killer cell survival. J Clin Invest 99:937, 1997
35. Foghsgaard L, Jaattela M: The ability of BHRF1 to inhibit apoptosis is dependent on stimulus and cell type. J Virol 71:7509, 1997
36. Jiwa NM, Oudejans JJ, Bai MC, Van den Brule AJ, Horstman A, Vos W, Van der Valk P, Kluin PM, Walboomers JM, Meijer CJ: Expression of bcl-2 protein and transcription of the Epstein-Barr virus bcl-2 homologue BHRF-1 in Hodgkin's disease: Implications for different pathogenic mechanisms. Histopathology 26:547, 1995
37. Hausen Hz, Schulte-Holthausen H, Klein G, Henle W, Henle G, Clifford P, Santesson L: EBV DNA in biopsies of Burkitt tumours and anaplastic carcinomas of the nasopharynx. Nature 228:1056, 1970
38. Suzushima H, Asou N, Fujimoto T, Nishimura S, Okubo T, Yamasaki H, Osato M, Matsuoka M, Tsukamoto A, Takai K, Kawano F, Takatsuki K: Lack of the expression of EBNA-2 and LMP-1 in T-cell neoplasms possessing Epstein-Barr virus. Blood 85:480, 1995
39. Milner AE, Grand RJ, Waters CM, Gregory CD: Apoptosis in Burkitt lymphoma cells is driven by c-myc. Oncogene 8:3385, 1993
40. Milner AE, Johnson GD, Gregory CD: Prevention of programmed cell death in Burkitt lymphoma cell lines by bcl-2-dependent and -independent mechanisms. Int J Cancer 52:636, 1992
41. Nonkwelo C, Ruf IK, Sample J: Interferon-independent and -induced regulation of Epstein-Barr virus EBNA-1 gene transcription in Burkitt lymphoma. J Virol 71:6887, 1997
42. Carson WE, Haldar S, Baiocchi RA, Croce CM, Caligiuri MA: The c-kit ligand suppresses apoptosis of human natural killer cells through the upregulation of bcl-2. Proc Natl Acad Sci USA 91:7553, 1994
43. Sartori A, Oliveira MA, Scott P, Trinchieri G: Metacyclogenesis modulates the ability of Leishmania promastigotes to induce IL-12 production in human mononuclear cells. J Immunol 159:2849, 1997
44. Kanegane H, Wang F, Tosato G: Virus-cell interactions in a natural killer-like cell line from a patient with lymphoblastic lymphoma. Blood 88:4667, 1996
45. Kaneko T, Fukuda J, Yoshihara T, Zheng H, Mori S, Mizoguchi H, Oshimi K: Nasal natural killer (NK) cell lymphoma: Report of a case with activated NK cells containing Epstein-Barr virus and expressing CD21 antigen, and comparative studies of their phenotype and cytotoxicity with normal NK cells. Br J Haematol 91:355, 1995
46. Kondo M, Weissman IL, Akashi K: Identification of clonogenic common lymphoid progenitors in mouse bone marrow, Cell 91:661, 1997
47. Galy A, Travis M, Cen D, Chen B: Human T, B, natural killer, and dendritic cells arise from a common bone marrow progenitor cell subset. Immunity 3:459, 1995
48. Fairbairn LJ, Cowling GJ, Reipert BM, Dexter TM: Suppression of apoptosis allows differentiation and development of a multipotent hemopoietic cell line in the absence of added growth factors. Cell 74:823, 1993
49. Lagasse E, Weissman IL: Enforced expression of Bcl-2 in monocytes rescues macrophages and partially reverses osteopetrosis in op/op mice. Cell 89:1021, 1997
50. Klampfer L, Zhang J, Zelenetz AO, Uchida H, Nimer SD: The AML1/ETO fusion protein activates transcription of BCL-2. Proc Natl Acad Sci USA 93:14059, 1996
51. Campos L, Sabido O, Rouault JP, Guyotat D: Effects of BCL-2 antisense oligodeoxynucleotides on in vitro proliferation and survival of normal marrow progenitors and leukemic cells. Blood 84:595, 1994
52. Stoetzer OJ, Nussler V, Darsow M, Gullis E, Pelka-Fleischer R, Scheel U, Wilmanns W: Association of bcl-2, bax, bcl-xL and interleukin-1 beta-converting enzyme expression with initial response to chemotherapy in acute myeloid leukemia. Leukemia 10:S18, 1996 (suppl 3)
53. Yang XF, Weber GF, Cantor H: A novel Bcl-x isoform connected to the T cell receptor regulates apoptosis in T cells. Immunity 7:629, 1997