Notch(spl) is deficient for inductive processes in the eye, and E(spl)(D) enhances split by interfering with proneural activity

Developmental Biology

Volumn 208, Issue 2, 1999, Pages 406-415

  Nagel, Anja C ^a   Preiss, Anette ^a  

^a UNIVERSITY OF HOHENHEIM   (Germany)

Author keywords

Atonal; E(spl); Eye development; Inductive signals; Notch; Proneural genes; Split

Indexed keywords

ARTICLE; DROSOPHILA; EMBRYO; EYE DEVELOPMENT; GENE MUTATION; NONHUMAN; PHOTORECEPTOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; ALLELE; ANIMAL; BIOLOGICAL MODEL; EMBRYO INDUCTION; EYE; GENE DOSAGE; GENETICS; METABOLISM; MORPHOGENESIS; MUTATION; PRENATAL DEVELOPMENT; PROTEIN BINDING; ULTRASTRUCTURE;

DROSOPHILA; HEXAPODA;

BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; DNA BINDING PROTEIN; DROSOPHILA PROTEIN; E(SPL) REGION TRANSCRIPT MDELTA PROTEIN, DROSOPHILA; HELIX LOOP HELIX PROTEIN; INSECT PROTEIN; MEMBRANE PROTEIN; NOTCH PROTEIN, DROSOPHILA; NOTCH RECEPTOR; REPRESSOR PROTEIN;

ALLELES; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BODY PATTERNING; DNA-BINDING PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; EMBRYONIC INDUCTION; EYE; GENE DOSAGE; HELIX-LOOP-HELIX MOTIFS; INSECT PROTEINS; MEMBRANE PROTEINS; MODELS, BIOLOGICAL; MUTATION; PROTEIN BINDING; RECEPTORS, NOTCH; REPRESSOR PROTEINS;

EID: 0033560170     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.1999.9203     Document Type: Article

References (24)

1. Alifragis P., Poortinga G., Parkhurst S. M., Delidakis C. A network of interacting transcriptional regulators involved inDrosophila. Proc. Natl. Acad. Sci USA. 94:1997;13099-13104.
2. Artavanis-Tsakonas S., Matsuno K., Fortini M. E. Notch. Science. 268:1995;225-232.
3. Ausubel F. M., Brent R., Kingston R. E., Moore D. D., Seidman J. G., Smith G. A., Struhl K. Current Protocols in Molecular Biology. 1995;Wiley, New York.
4. Baker N. E., Mlodzik M., Rubin G. M. Spacing differentiation in the developingDrosophilascabrous. Science. 250:1990;1370-1377.
5. Baker N. E., Yu S., Han D. Evolution of proneural atonal expression during distinct regulatory phases in the developingDrosophila. Curr. Biol. 6:1996;1290-1301.
6. Baker N. E., Yu S. Y. Proneural function of neurogenic genes in the developingDrosophila. Curr. Biol. 7:1997;122-132.
7. Brennan K., Tateson R., Lewis K., Martinez-Arias A. A functional analysis ofNotchDrosophila. Genetics. 147:1997;177-188.
8. Cagan R. L., Ready D. F. NotchDrosophila. Genes Dev. 3:1989;1099-1112.
9. DDrosophila melanogaster. Roux's Arch. Dev. Biol. 198:1990;286-294.
10. de Celis J. F., de Celis J., Ligoxygakis P., Preiss A., Delidakis C., Bray S. Functional relationship betweenNotch, Su(H)E(spl)E(spl)Notch. Development. 122:1996;2719-2728.
11. Dickson B., Hafen E. Genetic dissection of eye development inDrosophila. The Development ofDrosophila melanogaster. 1993;Cold Spring Harbor Laboratory Press, New York. p. 1327-1364.
12. Fisher A. L., Caudy M. Groucho proteins: Transcriptional corepressors for specific subsets of DNA-binding transcription factors in vertebrates and invertebrates. Genes Dev. 12:1998;1931-1940.
13. Halder G., Callaerts P., Flister S., Walldorf U., Kloter U., Gehring W. J. Eyeless initiates the expression of bothsine oculiseyes absentDrosophila. Development. 125:1998;2193-2202.
14. Hartley D. A., Xu T., Artavanis-Tsakonas S. The embryonic expression of theNotchDrosophila melanogaster. EMBO J. 6:1987;3407-3417.
15. Klämbt C., Knust E., Tietze K., Campos-Ortega J. A. Closely related transcripts encoded by the neurogenic gene complexEnhancer of splitDrosophila melanogaster. EMBO J. 8:1989;203-210.
16. Lai E. C., Burks C., Posakony J. W. The K box, a conserved 3′ UTR sequence motif, negatively regulates accumulation ofEnhancer of split. Development. 125:1998;4077-4088.
17. Ligoxygakis P., Yu S. Y., Delidakis C., Baker N. A subset ofNotchDrosophilaSu(H)E(spl). Development. 125:1998;2893-2900.
18. Lindsley D. L., Zimm G. G. The Genome ofDrosophila melanogaster. 1992;Academic Press, San Diego.
19. DDrosophila.
20. Paroush Z., Finley R. L. J., Kidd T., Wainwright S. M., Ingham P. W., Brent R., Ish-Horowicz D. Groucho is required forDrosophila. Cell. 79:1994;805-815.
21. Posakony J. W. Nature versus nurture: Asymmetric cell divisions inDrosophila. Cell. 76:1994;415-418.
22. DDrosophila, Proc. Natl. Acad. Sci USA. 89:1992;6152-6156.
23. Welshons W. J. Dosage experiments withsplitsplit. Drosophila Inf. Serv. 30:1956;157-158.
24. Wolff T., Ready D. F. Pattern formation in theDrosophila. Bate M., Martinez-Ariaz A. The Development ofDrosophila melanogaster. 1993;1091-1129 Cold Spring Harbor Laboratory Press, New York.