ATP-dependent colchicine transport by human erythrocyte glutathione conjugate transporter

Toxicology and Applied Pharmacology

Volumn 155, Issue 3, 1999, Pages 215-226

  Awasthi, Sanjay ^a   Singhal, Sharad S ^a   Pandya, Utpal ^a   Gopal, Sanjiv ^a   Zimniak, Piotr ^b   Singh, Shivendra V ^c   Awasthi, Yogesh C ^a  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^b CENTRAL ARKANSAS VETERANS HEALTHCARE SYSTEM   (United States)

^c MERCY HOSPITAL OF PITTSBURGH   (United States)

Author keywords

Colchicine; Drug resistance; Glutathione; Glutathione conjugate transport; Leukotrienes

Indexed keywords

ADENOSINE TRIPHOSPHATE; COLCHICINE; DOXORUBICIN; GLUTATHIONE; GLYCOPROTEIN P; LEUKOTRIENE;

ACTIVE TRANSPORT; ARTICLE; BIOTRANSFORMATION; DRUG TRANSPORT; ENZYME PURIFICATION; ENZYME SPECIFICITY; ERYTHROCYTE MEMBRANE; HUMAN; HUMAN CELL; MEMBRANE VESICLE; POLYMERIZATION; PROTEOLIPOSOME; TISSUE SPECIFICITY;

EID: 0033559441     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.1998.8617     Document Type: Article

References (50)

1. m transport of dinitrophenyl glutathione in inside out vesicles from human erythrocytes. Biochim. Biophys. Acta 1103, 115-119.
2. Awasthi, S., Singhal, S. S., Pikula, S., Piper, J. T., Srivastava, S. K., Torman, R. T., Pikula, J., Lin, J. T., Singh, S. V., Zimniak, P., and Awasthi, Y. C. (1998b). ATP-dependent human erythrocyte glutathione-conjugate transporter. II. Functional reconstitution of transport activity. Biochemistry 37, 5239-5248.
3. Awasthi, S., Singhal, S. S., Srivastava, S. K., Torman, R. T., Zimniak, P., Pikula, J., Singh, S. V., Piper, J. T., Awasthi, Y. C., and Pikula, S. (1998a). ATP-dependent human erythrocyte glutathione-conjugate transporter. I. Purification, photoaffinity labeling, and kinetic characteristics of ATPase activity. Biochemistry 37, 5231-5238.
4. Awasthi, S., Singhal, S. S., Srivastava, S. K., Zimniak, P., Bajpai, K. K., Saxena, M., Sharma, R., Ziller, S. A., Frenkel, E. P., Singh, S. V., He, N-G., and Awasthi, Y. C. (1994). Adenosine triphosphate-dependent transport of doxorubicin, daunomycin, and vinblastine in human tissues by a mechanism distinct from the P-glycoprotein. J. Clin. Invest. 93, 958-965.
5. Awasthi, S., Srivastava, S. K., Ahmad, F., Ahmad, H., and Ansari, G. A. S. (1993). Interactions of glutathione S-transferase pi with ethacrynic acid and its glutathione conjugate. Biochim. Biophys. Acta 1164, 173-178.
6. Awasthi, Y. C., Sharma, R., and Singhal, S. S. (1994). Human glutathione S-transferases. Int. J. Biochem. Cell Biol. 26, 295-308. [Review]
7. Awasthi, Y. C., Singhal, S. S., Gupta, S., Ahmad, H., Zimniak, P., Radominska, A., Lester, R., and Sharma, R. (1991). Purification and characterization of an ATPase from human liver which catalyzes ATP hydrolysis in the presence of the conjugates of bilirubin, bile acids and glutathione. Biochem. Biophys. Res. Commun. 175, 1090-1096.
8. Ball, H. A., Cook, J. A., Spicer, K. M., Hsu, C. Y., and Halushka, P. V. (1988). Oleic acid-induced pulmonary injury in rats: Potential role of sulfidopeptide leukotrienes. Circulatory Shock 26, 59-70.
9. Bilzer, M., Krauth-Siegel, R. L., Schirmer, R. H., Akerboom, T. P., Sies, H., and Schulz, G. E. (1984). Interaction of a glutathione S-conjugate with glutathione reductase. Kinetic and x-ray crystallographic studies. Eur. J. Biochem. 138, 373-378.
10. Board, P. G. (1981). Transport of glutathione S-conjugates from human erythrocytes. FEBS Lett. 124, 163-165.
11. Cole, S. P., Bhardwaj, G., Gerlach, J. H., Mackie, J. E., Grant, C. E., Almquist, K. C., Stewart, A. J., Kurz, E. U., Duncan, A. M., and Deeley, R. G. (1992). Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line. Science (Washington, D.C.) 258, 1650-1654.
12. Ducloux, D., Schuller, V., Bresson-Vautrin, C., and Chalopin, J. M. (1997). Colchicine myopathy in renal transplant recipients on cyclosporin. Nephrol. Dial. Transplant. 12, 2389-2392.
13. Ebron-McCoy, M. T., Nichols, H. P., Andrews, J. E. X., and Kavlock, R. J. (1995). Profile of procarbazine-induced embryotoxicity in an embryo hepatocyte co-culture system and after in utero glutathione depletion. Teratog. Carcinog. Mutagen. 15, 33-42.
14. Evans, T. I., Wheeler, M. T., Small, R. E., Breitbach, S. A., Sanders, K. M., and Roberts, W. N. (1996). A comprehensive investigation of impatient intravenous colchicine use shows more education is needed. J. Rheumatol. 23, 143-148.
15. Finklestein, M., Goldman, L., Grace, N. D., Foley, M., and Randall, N. (1987). Granulocytopenia complicating colchicine therapy for primary biliary cirrhosis. Gastroenterology 93, 1231-1235.
16. Flower, R. J., Moncada, S., and Vane, J. R. (1985). Analgesic-antipyretics and anti-inflammatory agents. Drugs employed in the treatment of gout. In The Pharmacological Basis of Therapeutics. (A. Gilman, L. S. Goodman, T. W. Rall, and F. Murad, Eds.), pp. 708-710. MacMillan Publishing, New York.
17. Hammarstrom, S. (1983). Leukotrienes. Annu. Rev. Biochem. 52, 355-377.
18. Hastie, S. B. (1991). Interactions of colchicine with tubulin. Pharmacol. Ther. 51, 377-401.
19. Heaney, D., Derghazarian, C. B., Pineo, G. F., and Ali, M. A. (1976). Massive colchicine overdose: A report on the toxicity. Am. J. Med. Sci. 271, 233-238.
20. Hoffman, R. S., Shih, R. D., and Baruch, J. M. (1993). Outpatient colchicine poisoning. Del. Med. J. 65, 257-260.
21. Jakoby, W. B. (1978). The glutathione S-transferases: A group of multifunctional detoxification proteins. Adv. Enzymol. Relat. Areas Mol. Biol. 46, 383-414.
22. Jap, B. K., and Walian, P. J. (1996). Structure and functional mechanism of porins. Physiol. Rev. 76, 1073-1088. [Review]
23. Juliano, R. L., and Ling, V. (1976). A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Biochim. Biophys. Acta 455, 152-162.
24. 2+)-ATPase from the membranes of a human oat cell carcinoma. J. Biol. Chem. 259, 10919-10924.
25. Kuncl, R. W., Duncan, G., Watson, D., Alderson, K., Rogawski, M. A., and Peper, M. (1987). Colchicine myopathy and neuropathy. N. Engl. J. Med. 316, 1562-1568.
26. LaBelle, E. F., Singh, S. V., Srivastava, S. K., and Awasthi, Y. C. (1986). Dinitrophenyl glutathione efflux from human erythrocytes is a primary active ATP-dependent transport. Biochem. J. 238, 443-449.
27. Lautier, D., Canitrot, Y., Deeley, R. G., and Cole, S. P. (1996). Multidrug resistance mediated by the multidrug resistance protein (MRP) gene. Biochem. Pharmacol. 52, 967-977. [Review]
28. Levy, M., Spino, M., and Read, S. E. (1991). Colchicine: A state-of-the-art. Pharmacotherapy 11, 196-211. [Review]
29. Loe, D. W., Almquist, K. C., Deeley, R. G., and Cole, S. P. (1996). Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles. Demonstration of glutathione-dependent vincristine transport. J. Biol. Chem. 271, 9675-9682.
30. Malawista, S. E. (1975). The action of colchicine in acute gouty arthritis. Arthritis Rheum. 18, 835-846.
31. Mannervik, B., and Danielson, U. H. (1988). Glutathione transferases - Structure and catalytic activity. CRC Crit. Rev. Biochem. 23, 283-337. [Review]
32. Maurizi, M., Delorme, N., Laprevote-Heully, M. C., Lambert, H., and Larcan, A. (1986). Acute respiratory distress syndrome in adults in colchicine poisoning. Ann. Fr. Anesth. Reanim. 5, 530-532.
33. Meier, P. J., Sztul, E. S., Reuben, A., and Boyer, J. L. (1984). Structural and functional polarity of canalicular and basolateral plasma membrane vesicles isolated in high yield from rat liver. J. Cell Biol. 98, 991-1000.
34. Mertens, J. J., Gibson, N. W., Lau, S. S., and Monks, T. J. (1995). Reactive oxygen species and DNA damage in 2-bromo-(glutathion-S-yl) hydroquinone-mediated cytotoxicity. Arch. Biochem. Biophys. 320, 51-58.
35. Miller, C., and Racker, E. (1976). Fusion of phospholipid vesicles reconstituted with cytochrome c oxidase and mitochondrial hydrophobic protein. J. Membr. Biol. 26, 319-333.
36. Monks, T. J., Lau, S. S., Highet, R. J., and Gillette, J. R. (1985). Glutathione conjugates of 2-bromohydroquinone are nephrotoxic. Drug Metab. Dispos. 13, 553-559.
37. Naidus, R. M., Rodvien, R., and Mielke, C. H. (1977). Colchicine toxicity. Arch. Intern. Med. 137, 394-397.
38. Ohtsuki, T., Matsumoto, M., Hayashi, Y., Yamamoto, K., Kitagawa, K., Ogawa, S., Yamamoto, S., and Kamada, T. (1995). Reperfusion induces 5-lipoxygenase translocation and leukotriene C4 production in ischemic brain. Am. J. Physiol. 268, 1249-1257.
39. Pikula, S., Bandorowicz-Pikula, J., Awasthi, S., and Awasthi, Y. C. (1996). Differential staining of human erythrocyte membrane proteins by coomassie and silver: Implications in the assessment of homogeneity of membrane proteins. Biochem. Arch. 12, 237-243.
40. Saxena, M., Singhal, S. S., Awasthi, S., Singh, S. V., LaBelle, E. F., Zimniak, P., and Awasthi, Y. C. (1992). Dinitrophenyl S-glutathione ATPase purified from human muscle catalyzes ATP hydrolysis in the presence of leukotrienes. Arch. Biochem. Biophys. 298, 231-237.
41. Shapiro, A. B., and Ling, V. (1994). ATPase activity of purified and reconstituted P-glycoprotein from Chinese hamster ovary cells. J. Biol. Chem. 269, 3745-3754.
42. Sharma, R., Gupta, S., Singh, S. V., Medh, R. D., Ahmad, H., LaBelle, E. F., and Awasthi, Y. C. (1990). Purification and characterization of dinitrophenylglutathione ATPase of human erythrocytes and its expression in other tissues. Biochem. Biophys. Res. Commun. 171, 155-161.
43. Singhal, S. S., Sharma, R., Gupta, S., Ahmad, H., Zimniak, P., Radominska, A., Lester, R., and Awasthi, Y. C. (1991). The anionic conjugates of bilirubin and bile acids stimulate ATP hydrolysis by S-(dinitrophenyl)glutathione ATPase of human erythrocyte. FEBS Lett. 281, 255-257.
44. Smit, J. J., Schinkel, A. H., Mol, C. A., Majoor, D., Mooi, W. J., Jongsma, A. P., Lincke, C. R., and Borst, P. (1994). Tissue distribution of the human MDR3 P-glycoprotein. Lab Invest. 71, 638-649.
45. Smith, L. J., Shamsuddin, M., Anderson, J., and Hsueh, W. (1988). Hyperoxic lung damage in mice: Appearance and bioconversion of peptide leukotrienes. J. Appl Physiol. 64, 944-951.
46. Stanley, M. W., Taurog, J. D., and Snover, D. C. (1984). Fatal colchicine toxicity: Report of a case. Clin. Exp. Rheumatol. 3, 167-171.
47. Stapczynski, J. S., Rothstein, R. J., Gaye, W. A., and Niemann, J. T. (1981). Colchicine overdose: Report of two cases and review of the literature. Ann. Emerg. Med. 10, 364-369.
48. Tandon, P., Barone, S., Mundy, W. R., and Tilson, H. A. (1994). Compensatory changes in the hippocampus following intradentate infusion of colchicine. Neurotoxicology 15, 513-524. [Review]
49. Yagi, Y. N. (1994). Induction of apoptotic cell death in differentiating neuroblastoma SH-SY5Y cells by colchicine. Biochem. Biophys. Res. Commun. 199, 807-817.
50. Zhang, X., Collins, K. I., and Greenberger, L. M. (1995). Functional evidence that transmembrane 12 and the loop between transmembrane 11 and 12 form part of the drug-binding domain in P-glycoprotein encoded by MDR 1. J. Biol. Chem. 270, 5441-5448.