Bootstrap approach for constructing confidence intervals for population pharmacokinetic parameters. II: A bootstrap modification of standard two-stage (STS) method for phase I trial

Statistics in Medicine

Volumn 18, Issue 5, 1999, Pages 601-612

  Yafune, Akifumi ^a,b   Ishiguro, Makio ^c  

^a KITASATO INSTITUTE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c INSTITUTE OF STATISTICAL MATHEMATICS   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CLINICAL RESEARCH; CONTROLLED STUDY; DRUG RESEARCH; HUMAN; PHARMACOKINETICS; POPULATION; SIMULATION; STATISTICAL ANALYSIS; VARIANCE;

CLINICAL TRIALS, PHASE I; CONFIDENCE INTERVALS; DATA INTERPRETATION, STATISTICAL; DEMOGRAPHY; HUMANS; MODELS, STATISTICAL; PHARMACOKINETICS;

EID: 0033559220     PISSN: 02776715     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0258(19990315)18:5<601::AID-SIM48>3.0.CO;2-L     Document Type: Article

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