Temporal sequence of transcription of perforin, Fas ligand, and tumor necrosis factor-α genes in rejecting skin allografts

Transplantation

Volumn 67, Issue 5, 1999, Pages 672-680

  Borson, Nancy D ^a   Strausbauch, Michael A ^a   Kennedy, Richard B ^a   Oda, Robert P ^a   Landers, James P ^b   Wettstein, Peter J ^a  

^a MAYO CLINIC   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FAS LIGAND; MESSENGER RNA; PERFORIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; GENETIC TRANSCRIPTION; GRAFT REJECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; SKIN ALLOGRAFT; WOUND HEALING;

EID: 0033559040     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199903150-00006     Document Type: Article

References (46)

1. Podack ER, Hengartner H, Lichtenheld MG. A central role of perforin in cytolysis? Annu. Rev. Immunol 1991; 9: 129-157.
2. Heusel JW, Wesselschmidt RL, Shresta S, Russell JH, Ley TJ. Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells. Cell 1994; 76: 977-987.
3. Shi L, Kam CM, Powers JC, Aebersold R, Greenberg AH. Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions. J Exp. Med 1992; 176: 1521-1529.
4. Nakajima H, Henkart PA. Cytotoxic lymphocyte granzymes trigger a target cell internal disintegration pathway leading to cytolysis and DNA breakdown. J Immunol 1994; 152: 1057-1063.
5. Walsh CM, Matloubian M, Liu CC, et al. Immune function in mice lacking the perforin gene. Proc. Natl. Acad. Sci. USA 1994; 91: 10854-10858.
6. Walsh CM, Hayashi F, Saffran DC, Ju ST, Berke G, Clark WR. Cell-mediated cytotoxicity results from, but may not be critical for, primary allograft rejection. J Immunol 1996; 156: 1436-1441.
7. Ratner A, Clark WR. Role of TNF-α in CD8+ cytotoxic T lymphocyte-mediated lysis. J Immunology 1993; 150: 4303-4314.
8. Glass A, Walsh CM, Lynch DH, Clark WR. Regulation of the fas lytic pathway in cloned CTL. Journal of Immunology 1996; 156: 3638-3644.
9. Kagi D, Vignaux F, Ledermann B, et al. Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicty Science 1994; 265: 528-530.
10. Schulz M, Schuurman HJ, Joergensen J, et al. Acute rejection of vascular heart allografts by perforin-deficient mice. Eur. J Immunol 1995; 25: 474-480.
11. Seino K, Kayagaki N, Bashuda H, Okumura K, Yagita H. Contribution of fas ligand to cardiac allograft rejection. International Immunology 1996; 8: 1347-1354.
12. Imagawa DK, Millis JM, Olthoff KM, et al. The role of tumor necrosis factor in allograft rejection. Transplantation 1990; 50: 189-193.
13. Lin H, Chensue SW, Strieter RM, et al. Antibodies against tumor necrosis factor prolong cardiac allograft survival in the rat. J Heart Lung Transplant 1992; 11: 330-335.
14. Piatak M, Jr., Luk KC, Williams B, Lifson JD. Quantitative competitive polymerase chain reaction for accurate quantitation of HIV DNA and RNA species. BioTechniques 1993; 14: 70-79.
15. Riedy MC, Timm EA, Jr., Stewart CC. Quantitative RT-PCR for measuring gene expression. BioTechniques 1995; 18: 70-76.
16. Personett DA, Chouinard M, Sugaya K, McKinney M. Simplified RT/PCR quantitation of gene transcripts in cultured neuroblastoma (SN49) and microglial (BV-2) cells using capillary electrophoresis and laser-induced fluorescence. J Neuro. Methods 1995; 65: 77-91.
17. Borson ND, Strausbauch MA, Wettstein PJ, Oda RP, Johnston SL, Landers JP. Direct quantitation of RNA transcripts by competitive single-tube RT-PCR and capillary electrophoresis. BioTechniques 1998; 25: 130-137.
18. Bailey DW, Usama B. A rapid method of grafting skin on tails of mice. Transplantation Bulletin 1960; 7: 424-428.
19. Dialynas DP, Wilde DB, Marrack P, et al. Characterization of the murine antigenic determinant designated L3T4a, recognized by monoclonal antibody GK1.5: expression of L3T4a by functional T cell clones appears to correlate primarily with Class II MHC antigen-reactivity. Immunol Rev. 1983; 74: 29.
20. Sheehan KCF, Ruddle NH, Schreiber RD. Generation and characterization of hamster monoclonal antibodies that neutralize murine tumor necrosis factors. J Immunol 1989; 142: 3884-3893.
21. Nevala WK, Paul C, Wettstein PJ. Reduced diversity of CTLs specific for multiple minor histocompatibility antigens relative to allograft rejection in vivo. J Immunol 1997; 158: 1102-1107.
22. Wettstein PJ, Korngold R. T cell subsets required for the generation of CTL activity directed toward single and multiple histocompatibility antigens. Transplantation 1991; 54: 296-307.
23. Esser MT, Dinglasan RD, Krishnamurthy B, Gullo CA, Graham MB, Braciale VL. IL-2 induces fas ligand/fas (CD95L/CD95) cytotoxicity in CD8+ and CD4+ T lymphocyte clones. J Immunol 1997; 158: 5612-5618.
24. Maury CPJ, Teppo Am Raised serum levels of cachetin/tumor necrosis factor a in renal allograft rejection. J Exp. Med 1987; 166: 1132-1137.
25. Fahey TJ, III, Turbeville T, McIntyre K. Differential TNF secretion by wound fibroblasts compared to normal fibroblasts in response to LPS. J Surg. Res. 1995; 58: 759-764.
26. Hubner G, Brauchle M, Smola H, Madlener M, Fassler R, Werner S. Differential regulation of pro-inflammatory cytokines during wound healing in normal and glucocorticoidtreated mice. Cytokine 1996; 8: 548-556.
27. Dieleman LA, Elson CO, Tennyson GS, Beagley KW. Kinetics of cytokine expression during healing of acute colitis in mice. Am J. Physiol. 1996; 271: G130-G136.
28. Quan D, Grant DR, Zhong RZ, Zhand Z, Garcia BM, Jevnikar Am Altered gene expression of cytokine, ICAm-1, and class II molecules precedes mouse intestinal allograft rejection. Transplantation 1994; 58: 808-816.
29. Dallman MJ, Larsen CP, Morris PJ. Cytokine gene transcription in vascularised organ grafts: analysis using semiquantitative polymerase chain reaction. J Exp. Med 1991; 174: 493-496.
30. Morgan CJ, Pelletier RP, Hernandez CJ, et al. Alloantigen-dependent endothelial phenotype and lymphokine mRNA expression in rejecting murine cardiac allografts. Transplantation 1993; 55: 919-923.
31. Larsen CP, Alexander DZ, Hendrix R, et al. Fas-mediated cytotoxicity. An immunoeffector or immunoregulatory pathway in T cell-mediated immune responses? Transplantation 1995; 60: 221-224.
32. Smyth MJ, Ortaldo JR, Shinkai YI, et al. Interleukin 2 induction of pore-forming protein gene expression in human peripheral blood CD8+ T cells. J Exp. Med 1990; 171: 1269-1281.
33. Esser MT, Krishnamurthy B, Braciale VL. Distinct T cell receptor signaling requirements for perform- or FasL-mediated by cytotoxicity. J Exp. Med 1996; 183: 1697-1706.
34. Strehlau J, Pavlakis M, Lipman M, et al. Quantitative detection of immune activation transcripts as a diagnostic tool in kidney transplantation. Proc. Natl. Acad. Sci. USA 1997; 94: 695-700.
35. Zheng L, Fisher G, Miller RE, Peschon J, Lynch DH, Lenardo MJ. Induction of apoptosis in mature T cells by tumour necrosis factor. Nature 1995; 377: 348-351.
36. Kainulainen V, Nelimarkka L, Jarvelainen H, Laato M, Jalkanen M, Elenius K. Suppression of syndecan-1 expression in endothelial cells by tumor necrosis factor-alpha. The Journal of Biological Chemistry 1996; 271: 18759-18766.
37. Cumberbatch M, Fielding I, Kimber I. Modulation of epidermal Langerhans' cell frequency by tumour necrosis factor-α. Immunology 1994; 81: 395-401.
38. Kondo S, Sauder DN. Tumor necrosis factor (TNF) receptor type 1 (p55) is a main mediator for TNF-α -induced skin inflammation. Eur. J Immunol 1997; 27: 1713-1718.
39. Colletti LM, Remick DG, Burtch GD, Kunkel SL, Strieter RM, Campbell DA, Jr. Role of tumor necrosis factor-α in the pathophysiologic alterations after hepatic ischemia/reperfusion injury in the rat. J Clin. Invest. 1990; 85: 1936-1943.
40. Bruce AJ, Boling W, Kindy MS, et al. Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors. Nature Medicine 1996; 2: 788-794.
41. Feiken E, Romer J, Eriksen J, Lund LR. Neutrophils express tumor necrosis factor-α during mouse skin wound healing. J Invest. Dermatol. 1995; 105: 120-123.
42. Kock A, Schwarz T, Kirnbauer R, et al. Human keratinocytes are a source for tumor necrosis factor a: evidence for synthesis and release upon stimulation with endotoxin or ultraviolet light. J Exp. Med 1990; 172: 1609-1614.
43. Harder J, Bartels J, Christophers E, Schroder JM. A peptide antibiotic from human skin. Nature 1997; 387: 861.
44. Cumberbatch M, Kimber I. Dermal tumour necrosis factor-α induces dendritic cell migration to draining lymph nodes, and possibly provides one stimulus for Langerhans' cell migration. Immunology 1992; 75: 257-263.
45. Sallusto F, A. L. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/ macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J Exp. Med 1994; 179: 1109-1118.
46. Matzinger P. Tolerance, danger, and the extended family. Annu. Rev. Immunol 1994; 12: 991-1045.