Castration differentially alters [3H]nisoxetine binding to norepinephrine uptake sites in olfactory bulb and frontal cortex of male rats

Synapse

Volumn 31, Issue 4, 1999, Pages 250-255

  Shang, Yili ^a   Boja, John W ^b   Dluzen, Dean E ^a,c  

^a Northeastern Ohio Medical University   (United States)

^b College of Medicine ^*  (United States)

^c NORTHEAST OHIO MEDICAL UNIVERSITY   (United States)

Author keywords

Androgens; Depression; Memory recognition; Norepinephrine transporter; Olfaction

Indexed keywords

CARRIER PROTEIN; NISOXETINE; NORADRENALIN; SEX HORMONE; TESTOSTERONE; TRITIUM;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CASTRATION; CONTROLLED STUDY; DEPRESSION; DISSOCIATION CONSTANT; DRUG BINDING SITE; DRUG UPTAKE; FRONTAL CORTEX; MALE; NONHUMAN; NORADRENERGIC SYSTEM; OLFACTORY BULB; PRIORITY JOURNAL; RAT; SMELLING; SYNAPTOSOME;

ANIMALS; FLUOXETINE; FRONTAL LOBE; KINETICS; MALE; NOREPINEPHRINE; OLFACTORY BULB; ORCHIECTOMY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC; SYNAPTOSOMES; TESTOSTERONE;

EID: 0033558999     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2396(19990315)31:4<250::AID-SYN2>3.0.CO;2-Z     Document Type: Article

References (54)

1. Boja JW, McNeil RM, Lewin AH, Abraham P, Carroll FI, Kuhar MJ. 1992. Selective dopamine transporter inhibition by cocaine analogs. NeuroReport 3:984-986.
2. Bosse R, Rivest R, Di Paolo T. 1997. Ovariectomy and estradiol treatment affect the dopamine transporter and its gene expression in the rat brain. Mol Brain Res 46:343-346.
3. Bradford MM. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
4. Brann DW, Hendry LB, Mahesh VB. 1995. Emerging diversities in the mechanism of action of steroid hormones. J Steroid Biochem Mol Biol 52:113-133.
5. 3H]nisoxetine autoradiography. Brain Res 582: 208-214.
6. Brennan P, Kaba H, Keverne EB. 1990. Olfactory recognition: A simple memory system. Science 250:1223-1226.
7. Brown RE. 1977. Odor preference and urine-making scales in male and female rats: Effects of gonadectomy and sexual experience on responses to conspecific odors. J Comp Physiol Psychol 91:1190-1206.
8. Cardinali DP, Gomez E. 1977. Changes in hypothalamic noradrenaline, dopamine and serotonin uptake after oestradiol administration to rats. J Endocrinol 73:181:182.
9. Carr WJ, Loeb LS, Dissinger ML. 1965. Responses of rats to sex odors. J Comp Physiol Psychol 59:370-377.
10. Carr WJ, Loeb LS, Wylie NR. 1966. Responses to feminine odors in normal and castrated rats. J Comp Physiol Psychol 62:336-338.
11. 3H] norepinephrine uptake and effect of DSP-4 lesioning and antidepressant treatments. Neuropharmacology 35:63-70.
12. Cooper JR, Bloom FE, Roth RH. 1996. The biochemical basis of neuropharmacology. New York: Oxford University Press.
13. Cornwell-Jones CA. 1988. DSP4, a noradrenergic neurotoxin, impairs male rats' attraction to conspecific odors. Behav Neural Biol 50:1-15.
14. Cornwell-Jones CA, Marasco EM. 1980. Castration decreases olfactory bulb norepinephrine in male rats but not hamsters. Brain Res 183:377-382.
15. Cubells JF, Kim KS, Baker H, Volpe BT, Chung Y, Houpt TA, Wessel TC, Joh TH. 1995. Differential in vivo regulation of mRNA encoding the norepinephrine transporter and tyrosine hydroxylase in rat adrenal medulla and locus coeruleus. J Neurochem 65:502-509.
16. Dluzen DE, Ramirez VD. 1983. Localized and discrete changes in neuropeptide (LHRH and TRH) and neurotransmitter (NE and DA) concentrations within the olfactory bulbs of male mice as a function of social interaction. Horm Behav 17:139-145.
17. Dluzen DE, Ramirez VD. 1987. Involvement of olfactory bulb catecholamines and luteinizing hormone-releasing hormone in response to social stimuli mediating reproductive functions. Ann NY Acad Sci 519:252-268.
18. Dluzen DE, Ramirez VD. 1989. Receptive female rats stimulate norepinephrine release from olfactory bulbs of freely behaving male rats. Neuroendocrinology 49:28-32.
19. Dluzen DE, Ramirez VD, Carter CS, Getz LL. 1981. Male vole urine changes luteinizing hormone-releasing hormone and norepinephrine in female olfactory bulb. Science 212:573-575.
20. 3H-5-hydroxytrptamine by hypothalamic tissue in vitro. Br J Pharmacol 47:647p-648p.
21. Fumagalli F, Jones S, Bosse R, Jaber M, Giros B, Missale C, Wightman RM, Caron MG. 1998. Inactivation of the dopamine transporter reveals essential roles of dopamine in the control of locomotion, psychostimulant response, and pituitary function. Adv Pharmacol 42:179-182.
22. 3H]nisoxetine binding in rat brain. J Neurochem 64:2792-2800.
23. 3H](-)-norepinephrine into synaptosomes from rat cerebral cortex and hypothalamus. Brain Res 277:163-168.
24. Gray CM, Freeman WJ, Skinner JE. 1986. Chemical dependencies of learning in the rabbit olfactory bulb: Acquisition of the transient spatial pattern change depends on norepinephrine. Behav Neurosci 100:585-596.
25. Guan X, Dluzen D. 1991. Castration reduces potassium-stimulated norepinephrine release from superfused olfactory bulbs of male rats. Brain Res 568:147-151.
26. Guan X, Dluzen DE. 1994. L-dopa reverses castration-induced disruption of dishabituation responses to female chemical cues in male rats. Pharmacol Biochem Behav 48:515-519.
27. Guan X, Blank J, Dluzen DE. 1993a. Depletion of olfactory bulb norepinephrine by 6-OHDA disrupts chemical cue but not social recognition responses in male rats. Brain Res 622:51-57.
28. Guan X, Blank J, Dluzen DE. 1993b. Role of olfactory bulb norepinephrine in the identification and recognition of chemical cues. Physiol Behav 53:437-441.
29. Hrdina PD. 1983. Antidepressant binding: Implications for the mode of action and the biology of depression. Prog Neuropsychopharmacol Biol Psychiatry 7:457-462.
30. Iversen LL. 1975. Uptake process of biogenic amines. In: Iversen LL, Iversen SD, Snyder SH, editors. Handbook of psychopharmacology. New York: Plenum Press, pp 381-442.
31. Jaber M, Jones S, Giros B, Caron MG. 1997. The dopamine transporter: A crucial component regulating dopamine transmission. Mov Disord 12:629-633.
32. Jacobs BL. 1990. Locus coeruleus neuronal activity in behaving animals. In: Heal E, Marsden CA, editors. The pharmacology of noradrenaline in the central nervous system. Oxford, UK: Oxford University Press, pp 248-265.
33. Janowsky DS, Davis JM. 1970. Progesterone-estrogen effects on uptake and release of norepinephrine by synaptosomes. Life Sci 9:525-531.
34. Kaba H, Nakanishi S. 1995. Synaptic mechanisms of olfactory recognition memory. Rev Neurosci 6:125-141.
35. Kitayama I, Yaga T, Kayahara T, Nakano K, Murase S, Otani M, Nomura J. 1997. Long-term stress degenerates, but imipramine regenerates, noradrenergic axons in the rat cerebral cortex. Biol Psychiatry 42:687-696.
36. Lee CM, Javitch JA, Snyder SH. 1983. Recognition sites for norepinephrine uptake: Regulation by neurotransmitter. Science 220:626-629.
37. McLean JH, Shipley MT, Nickell WT, Aston-Jones G, Reyher CKH. 1989. Chemoanatomical organization of the noradrenergic input from locus coeruleus to the olfactory bulb of the adult rat. J Comp Neurol 285:339-349.
38. 3H]idazoxan binding sites in the frontal cortex of depressed suicide victims. Biol Psychiatry 34:498-501.
39. 3H-serotonin in rat brain synaptosomes. Res Commun Chem Pathol Pharmacol 7:233-236.
40. Pissonier D, Thiery JC, Fabre-Nys C, Poindron P, Keverne EB. 1985. The importance of olfactory bulb noradrenaline for maternal recognition in sheep. Physiol Behav 35:361-363.
41. Shang Y, Dluzen DE. 1998a. Castration reduces olfactory bulb norepinephrine transporter function as indicated by responses to noradrenergic uptake blockers. Brain Res 779:119-124.
42. Shang Y, Dluzen DE. 1998b. The effect of testosterone upon olfactory discrimination and olfactory bulb noradrenergic activity. Soc Neurosci 24:907 Abstract #358.3.
43. Shipley MT, Halloran FJ, de la Torre J. 1985. Surprisingly rich projection from locus coeruleus to the olfactory bulb in the rat. Brain Res 329:294-299.
44. 2 receptors. Mol Brain Res 27:337-341.
45. Sullivan RM, Wilson DA, Leon M. 1989. Norepinephrine and learning-induced plasticity in infant rat olfactory system. J Neurosci 9:3998-4006.
46. Sullivan RM, McGaugh JL, Leon M. 1991. Norepinephrine-induced plasticity and one-trial olfactory learning in neonatal rats. Dev Brain Res 60:219-228.
47. Szot P, Ashliegh A, Kohen R, Petri E, Dorsa DM, Veith R. 1993. Norepinephrine transporter mRNA is elevated in the locus coeruleus following short-and long-term desipramine treatment. Brain Res 618:308-312.
48. 3H]Nisoxetine: A radioligand for quantitation of norepinephrine uptake sites by autoradiography or by homogenate binding. J Pharmacol Exp Ther 260:427-436.
49. Tejani-Butt SM, Yang J. 1994. A time course of altered thyroid states on the noradrenergic system in rat brain by quantitative autoradiography. Neuroendocrinology 59:235-244.
50. 3H]Nisoxetine: A new radioligand for norepinephrine uptake sites in brain. Eur J Pharmacol 191:239-243.
51. Xiao Q, Yao Y, Tejani-Butt SM. 1995. Acute administration of α-methylpara-tyrosine alters levels of norepinephrine transporter mRNA in the rat brainstem. Mol Brain Res 30:389-392.
52. Yang S-P, Pau K-YF, Spies HG. 1997. Gonadectomy alters tyrosine hydroxylase and norepinephrine transporter mRNA levels in the locus coeruleus in rabbits. J Neuroendocrinology 9:763-768.
53. Zhu M-Y, Ordway GA. 1997. Down-regulation of norepinephrine transporters on PC12 cells by transporter inhibitors. J Neurochem 68:134-141.
54. Zhu M-Y, Blakely RD, Apparsundaram S, Ordway GA. 1998. Down-regulation of the human norepinephrine transporter in intact 293-hNET cells exposed to desipramine. J Neurochem 70:1547-1555.