Lateral mobility of proteins and lipids of cell surface membranes during aging: Do the data support 'The Membrane Hypothesis of Aging'?

Mechanisms of Ageing and Development

Volumn 107, Issue 3, 1999, Pages 299-322

  Kitani, Kenichi ^a  

^a NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

Author keywords

Aging; FRAP; Hepatocyte surface membranes; Intracellular enzyme activities; Lateral mobilities of proteins

Indexed keywords

ENZYME; LIPID; PROTEIN;

AGING; ANISOTROPY; BLEACHING; CELL MEMBRANE; CONFERENCE PAPER; DIFFUSION COEFFICIENT; ENZYME ACTIVITY; FLUORESCENCE; LIVER CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; RAT;

AGING; ANIMALS; CELL MEMBRANE; FEMALE; HUMANS; MALE; MEMBRANE LIPIDS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MODELS, BIOLOGICAL; RATS; RATS, INBRED F344; RATS, WISTAR;

ANIMALIA;

EID: 0033558962     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0047-6374(98)00139-0     Document Type: Conference Paper

References (52)

1. Armbrecht, H.J., Bimbaum, L.S., Zenser, J.V., Davis, B.B., 1982. Ethanol-induced disordering of membranes from different age groups of C57BV6MNIA mice. Exp. Gerontol. 17, 41-48.
2. Axelrod, D., Koppel, D.E., Schlessinger, J., Elson, E., Webb, W.U., 1976. Mobility measurement by analysis of fluorescence photobleaching recovery kinetics. J. Biophys. 16, 1055-1069.
3. Carrillo, M.C., Kitani, K., Kanai, S., Sato, Y., Nokubo, M., Ohta, M., Otsubo, K., 1989. Differences in the influence of diet on hepatic glutathione S-transferase activity and glutathione content between young and old C57 black female mice. Mech. Ageing Dev. 44, 749-753.
4. Carrillo, M.C., Nokubo, M., Sato, Y., Kanai, S., Ohta, M., Kitani, K., 1990. Effect of protein free diet on activities and subunits of glutathione S-transferase in livers of young and aged female rats. Mech. Ageing Dev. 56, 237-251.
5. Carrillo, M.C., Nokubo, M., Kitani, K., Satoh, K., Sato, K., 1991. Age-related alterations of enzyme activities and subunits of hepatic glutathione S-transferases in male and female Fischer-344 rats. Biochim. Biophys. Acta 1077, 325-331.
6. Carrillo, M.C., Kanai, S., Sato, Y., Kitani, K., 1992. Age-related changes in antioxidant enzyme activities are region and organ selective as well as sex in the rat. Mech. Ageing Dev. 65, 187-198.
7. Cimino, M., Vantini, G., Algeri, S., Curatola, G., Pezzoli, C., Stramentionoli, G., 1984. Age related modification of dopaminergic and β-adrenergic receptor system: restoration to normal activity by modifying membrane fluidity with S-adenosylmethionine. Life Sci. 34, 2029-2039.
8. De-Pont, J.J.H.H.M., Bonting, S.L., 1977. Permeability of membranes. In: Jamieson, G.A., Robinson, D.M. (Eds.), Mammalian cell membranes, vol. 4. Membranes and cellular functions. Butterworths, London UK, pp. 116-144.
9. Eaton, D.L., Klaassen, C.D., 1978. Carrier mediated transport of ouabain in isolated hepatocytes. J. Pharmacol. Exp. Ther. 205, 480-488.
10. Eaton, D.L., Klaassen, C.D., 1979. Effects of microsomal inducers on carrier-mediated transport systems in isolated hepatocytes. J. Pharmacol. Exp. Ther. 208, 208-381.
11. Fujita, S., Chiba, M., Suzuki, T., Kitani, K., 1986. Effect of senescence on the hepatic metabolism of drugs affecting the central nervous system in rats and mice. In: Kitani, K. (Ed.), Liver and Aging 1986: Liver and Brain, Elsevier Science Publishers, Amsterdam, pp. 103-114.
12. Gummucio, J.J., Valdiniesso, V.D., 1971. Studies on the mechanism of ethinyl estradiol impariment of bile flows and bile salt excretion in the rat. Gastroenterology 61, 339-344.
13. Hegner, D., Platt, D., 1975. Effect of essential phospholipids on the properties of ATPase of isolated rat liver plasma membranes of young and old animals. Mech. Ageing Dev. 4, 91-200.
14. Kimelberg, H.K., 1977. The influence of membrane fluidity on the activity of membrane-bound enzymes. In: Poste, G., Nicolson, G.L. (Eds.), Cell surface reviews; Vol. 3, Dynamic aspects of surface organization, Elsevier/North-Holland Biomedical Press, Amsterdam, pp. 205-293.
15. Kitani, K., 1988. Drugs and the ageing liver. Life Chem. Rep. 6, 143-230.
16. Kitani, K., 1991. Aging of the liver: facts and theories. Arch. Gerontol. Geriatr. 12, 233-254.
17. Kitani, K., Zs.-Nagy, I., 1996. The effect of ethinyl-estradiol treatment on the lateral mobility of lipids and proteins in hepatocyte plasma membrane of male rats (FRAP studies on liver smears). Int. Hepatol. Commun. 5, 236-243.
18. Kitani, K., Zs.-Nagy, I., 1998. Effect of spironolactone on lateral mobility of lipids in hepatocyte plasma membranes in the rat. Hepatol. Res. 12, 131-139.
19. Kitani, K., Zs.-Nagy, I., Kanai, S., Sato, Y., Ohta, M., 1988. Correlation between the biliary excretion of ouabain and the lateral mobility of hepatocyte plasma membrane proteins in the rat: the effects of age and spironolactone pretreatment. Hepatology 8, 125-131.
20. Kitani, K., Tanaka, S., Zs.-Nagy, I., 1998. Age dependence of the lateral diffusion coefficient of lipids and proteins in the hepatocyte plasma membranes of BN/Bi RijHsd rats as revealed by the smear-FRAP technique. Arch. Gerontol. Geriatr. 26, 257-273.
21. Klaassen, C.D., 1974. The effect of microsomal enzyme inducers on the biliary excretion of cardiac glycosides. J. Pharmacol. Exp. Ther. 191, 201-211.
22. Lindeman, R.D., Tobin, J.D., Shock, N.W., 1985. Longitudinal studies on the rate of decline in renal function with age. J. Am. Geriatr. Soc. 33, 278-285.
23. +) ATPase activity, surface membrane cholesterol and phopholipid, and fluorescence polarization in the rat. Hepatology 3, 481-488.
24. Nagy, K., Zs.-Nagy, V., Bertoni-Freddam, C., Zs.-Nagy, I., 1983. Alteration of the synaptosomal membrane 'microviscosity' in the brain cortex of rats during aging and centrophenoxine treatment. Arch. Gerontol. Geriatr. 2, 23-39.
25. Nokubo, M., 1985. Physical-chemical and biochemical differences in liver plasma membranes in aging F-344 rats. J. Gerontol. 40, 409-414.
26. Nokubo, M., Zs.-Nagy, I., Kitani, K., Ohta, M., 1988. Characterization of the autofluorescence of rat liver plasma membranes. Biochim. Biophys. Acta 939, 441-448.
27. Nokubo, M., Ohta, M., Kitani, K., Zs.-Nagy, I., 1989. Identification of protein-bound riboflavin in rat hepatocyte membrane as a source of autofluorescence. Biochim. Biophys. Acta 981, 303-308.
28. Ohta, M., Kitani, K., 1990. Age-dependent decrease in the hepatic uptake of taurocholic acid resembles that for ouabain. Biochem. Pharmacol. 39, 1223-1228.
29. Ohta, M., Kanai, S., Sato, Y., Kitani, K., 1988. Age-dependent decrease in the hepatic uptake and biliary excretion of ouabain in rats. Biochem. Pharmacol. 37, 935-942.
30. Rikans, L.E., Moore, D.R., Snowdon, C.D., 1991. Sex differences in the effects of aging on antioxidant defence mechanisms of rat liver. Biochim. Biophys. Acta 1074, 195-200.
31. Rogiers, V., Coecke, C., Vanderbergke, Y., Morel, F., Calloerts, A., Verley, C., Van Bezoojen, C.F.A., Guillouzo, A., Vergruysse, A., 1991. Effect of the aging process on the gender and phenobarbital dependent expression of glutathione S-transferase subunits in Brown Norway rat liver. Biochem. Pharmacol. 42, 491-498.
32. Rosario, E.J., Sutherland, E., Zaccaro, L., Simon, R., 1978. Ethinylestradiol administration selectively alters liver sinusoidal membrane lipid fluidity and protein composition. Biochemistry 27, 3939-3946.
33. Rowe, J.W., Andres, R., Tobin, J.D., Norris, A.H., Shock, N.W., 1976. The effect of age on creatinine clearance in men: a cross-sectional and longitudinal study. J. Gerontol. 31, 155-163.
34. Stacey, N.H., 1986. Effects of ethinyl estradiol on substrate uptake and efflux by isolated rat hepatocytes. Biochem. Pharmacol. 35, 2495-2500.
35. Semsei, I., Rao, G., Richardson, A., 1989. Changes in the expression of superoxide dismutase and catalase as a function of age and dietary restriction. Biochim. Biophys. Res. Commun. 164, 620-625.
36. Smith, D.J., Gordon, E.R., 1988. Role of liver plasma membrane fluidity in the pathogenesis of estrogen-induced cholestasis. J. Lab. Clin. Med. 112, 679-685.
37. Williams, L.R., Carter, O.B., Dunn, E., Conner, J.R., 1995. Indicators of oxidative stress in aged Fischer 344 rats: potential for neurotrophic treatment. In: Hann, I., Fischer, A., Yoshida M. (Eds.), Alzheimer's and Parkinson's diseases: Recent Advances, Plenum Publications, New York, pp. 641-646.
38. Wynne, H.A., Cope, L.H., Hend, B., Rawlins, M.D., James, O.F.W., 1990. The effect of age and frailty upon paracetamol conjugation in man. Age Ageing 13, 419-424.
39. Yguerabide, J., Schmidt, J.A., Yguerabide, E.E., 1982. Lateral mobility in membranes detected by fluorescence recovery after photobleaching. Biophys. J. 40, 69-75.
40. Yu, B.P., Suescun, B.A., Yang, S.Y., 1992. Effect of age-related lipid peroxidation on membrane fluidity and phospholipase A2: modulation by dietary restriction. Mech. Ageing Dev. 65, 17-33.
41. Zs.-Nagy, I., 1991. The horizons of interdisciplinary synthesis in experimental gerontology. A review. Arch. Gerontol. Geriatr. 12, 329-349.
42. Zs.-Nagy, I., 1994. The membrane hypothesis of aging, CRC Press, Boca Raton, FL.
43. Zs.-Nagy, I., Kitani, K., 1996. Age-dependence of the lateral mobility of lipids in hepatocyte plasma membrane of male rats and the effect of life-long dietary restricition. Arch. Gerontol. Geriatr. 23, 81-93.
44. Zs.-Nagy, I., Ohta, M., Kitani, K., Imahori, K., 1984. An automated method for measuring lateral mobility of proteins in the plasma membrane of cells. Mikroskopie 41, 12-25.
45. Zs.-Nagy, I., Kitani, K., Ohta, M., Zs.-Nagy, V., Imahori, K., 1986. Age-dependent decrease of the lateral diffusion constant of proteins in the plasma membrane of hepatocytes as revealed by fluorescence recovery after photobleaching in tissue smears. Arch. Gerontol. Geriatr. 5, 131-146.
46. Zs.-Nagy, I., Kitani, K., Ohta, M., Zs.-Nagy, V., Imahori, K., 1986. Age-estimation of rats based on the average lateral diffusion constant of hepatocyte membrane proteins as revealed by fluorescence recovery after photo-bleaching. Exp. Gerontol. 21, 555-563.
47. Zs.-Nagy, V., Zs.-Nagy, I., Kitani, K., Ohta, M., 1988. Possibilities and limitations of the smearing technique for cellular studies in compact tissues: a transmission electron microscopic analysis of liver smears. Tissue Cells 20, 229-237.
48. Zs.-Nagy, I., Kitani, K., Ohta, M., 1989. Age-dependence of the lateral mobility of proteins in the plasma membrane of hepatocytes of C57BV6 mice: FRAP studies on liver smears. J. Gerontol. Biol. Sci. 44, B83-87.
49. Zs.-Nagy, I., Cutler, R.G., Kitani, K., Ohta, M., 1993. Comparison of the lateral diffusion constant of hepatocyte membrane proteins in two wild mouse strains of considerably different longevity: FRAP studies on liver smears. J. Gerontol. Biol. Sci. 48, B86-B92.
50. Zs.-Nagy, I., Ohta, M., Kitani, K., Cutler, R.G., 1993. The effect of caloric restriction on the lateral diffusion constant of hepatocyte membrane proteins in C57BL/6J male mice of different ages: FRAP studies on liver smears. Mech. Ageing Dev. 71, 85-96.
51. Zs.-Nagy, I., Tanaka, S., Kitani, K., 1998. Age-dependence of the lateral diffusion coefficient of Con-A receptor protein in the skeletal muscle membrane of C57BV6J mice. Mech. Ageing Dev. 101, 257-268.
52. Zs.-Nagy, I., Tanaka, S., Kitani, K., 1998. Age-dependence of the lateral diffusion coefficient of the Con-A receptors in the plasma membrane of ex vivo prepared brain cortical nerve cells of BN/BiRij hsd rats. Exp. Brain Res. 124, 233-240.