Mapping and characterization of the functional domains of the nucleolar protein RNA helicase II/Gu

Experimental Cell Research

Volumn 247, Issue 2, 1999, Pages 389-398

  Ou, Yongchun ^a   Fritzler, Marvin J ^b   Valdez, Benigno C ^c   Rattner, Jerome B ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF CALGARY   (Canada)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Fibrillarin; Gu; Nuclear localization signal; Nucleolar targeting signal; Nucleolus; RNA helicase II

Indexed keywords

FIBRILLARIN; GREEN FLUORESCENT PROTEIN; RNA HELICASE;

ARTICLE; CELL GROWTH; CENTROSOME; HELA CELL; HUMAN; HUMAN CELL; NUCLEAR LOCALIZATION SIGNAL; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEIN DOMAIN;

EID: 0033558824     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.1998.4365     Document Type: Article

References (32)

1. Alberts B., Bray D., Lewis J., Raff M., Roberts K., Watson J. D. Molecular Biology of the Cell. 1994;Garland, New York/London. p. 913.
2. Adachi Y., Copeland T. D., Hatanaka M., Oroszlan S. Nucleolar targeting signal of Rex protein of human T-cell leukemia virus type I specifically binds to nucleolar shuttle protein B-23. J. Biol. Chem. 268:1993;13930-13934.
3. Arnett F. C., Reveille J. D., Valdez B. C. Autoantibodies to a nucleolar RNA helicase protein in patients with connective tissue diseases. Arthritis Rheum. 40:1997;1487-1492.
4. Bastos R, Ribas de Pouplana L., Enarson M., Bodoor K., Burke B. Nup84, a novel nucleoporin that is associated with CAN/Nup214 on the cytoplasmic face of the nuclear pore complex. J. Cell Biol. 137:1997;989-1000.
5. Boulikas T. Nuclear localisation signals (NLS). Crit. Rev. Eukaryot. Gene Exp. 3:1993;193-227.
6. Dundr M., Meier U. T., Lewis N., Rekosh D., Hammarskjold M. L., Olson M. O. J. A class of nonribosomal nucleolar components is located in chromosome periphery and in nucleolus-derived foci during anaphase and telophase. Chromosoma. 106:1997;407-417.
7. Flores-Rozas H., Hurwitz J. Characterization of a new RNA helicase from nuclear extracts of HeLa cells which translocates in the 5′ to 3′ direction. J. Biol. Chem. 268:1993;21372-21383.
8. Girard J. P., Bagni C., Caizergues-Ferrer M., Amalric F., Lapeyre B. Identification of a segment of the small nucleolar ribonucleoprotein-associated protein GAR1 that is sufficient for nucleolar accumulation. J. Biol. Chem. 269:1994;18499-18506.
9. Gururajan R., Mathews L., Longo F., Weeks D. L. An3 mRNA encodes an RNA helicase that colocalizes with nucleoli inXenopus. Proc. Natl. Acad. Sci. USA. 91:1994;2056-2060.
10. Hirling H., Scheffner M., Restle T., Stahl H. RNA helicase activity associated with the human p68 protein. Nature (London). 339:1989;562-564.
11. Iggo R. D., Jamieson D. J., MacNeill S. A., Southgate J., McPheat J., Lane D. P. p68 RNA helicase: Identification of a nucleolar form and cloning of related genes containing a conserved intron in yeasts. Mol. Cell Biol. 11:1991;1326-1333.
12. Iost I., Dreyfus M. mRNA can be stabilized by DEAD-box proteins. Nature (London). 372:1994;193-196.
13. Lane D. P., Hoeffler W. K. SV40 large T shares an antigenic determinant with a cellular protein of molecular weight 68,000. Nature (London). 288:1980;167-170.
14. Liang S., Hitomi M., Hu Y. H., Liu Y., Tartakoff A. M. A DEAD-box-family protein is required for nucleocytoplasmic transport of yeast mRNA. Mol. Cell Biol. 16:1996;5139-5146.
15. Linder P., Lasko P. F., Leroy P., Nielsen P., Nishi K., Schnier J., Slonimski P. P. Birth of the D-E-A-D box. Nature (London). 337:1989;121-122.
16. Margossian S. P., Li H., Zassenhaus H. P., Butow R. A. The DExH box protein Suv3p is a component of a yeast mitochondrial 3′-to-5′ exoribonuclease that suppresses group I intron toxicity. Cell. 73:1996;837-840.
17. O'Day C. L., Chavanikamannil F., Abelson J. 18S rRNA processing requires the RNA helicase-like protein Rrp3. Nucleic Acids Res. 24:1996;3201-3207.
18. Py B., Higgins C. F., Krisch H. M., Carpousis A. J. A DEAD-box RNA helicase in theEscherichia coli. Nature (London). 381:1996;169-172.
19. Ripmaster T. L., Vaughn G. P., Woolford J. L. Jr. A putative ATP-dependent RNA helicase involved in Saccharomyces cerevisiae ribosome assembly. Proc. Natl. Acad. Sci. USA. 89:1992;11131-11135.
20. Sachs A. B., Davis R. W. Translation initiation and ribosomal biogenesis: Involvement of a putative rRNA helicase and RPL46. Science. 247:1990;1077-1079.
21. Schmid S. R., Linder P. D-E-A-D protein family of putative RNA helicases. Mol. Microbiol. 6:1992;283-297.
22. Schmidt-Zachmann M. S., Nigg E. A. Protein localisation to the nucleolus: A search for targeting domains in nucleolin. J. Cell Sci. 105:1993;799-806.
23. Seraphin B., Simon M., Boulet A., Faye G. Mitochondrial splicing requires a protein from a novel helicase family. Nature (London). 337:1989;84-87.
24. Strauss E. J., Guthrie C. PRP28, a 'DEAD-box' protein, is required for the first step of mRNA splicing in vitro. Nucleic Acids Res. 22:1994;3187-3193.
25. Valdez B. C., Hening D., Busch R. K., Woods K., Flores-Rozas H., Hurwitz J., Perlaky L., Busch H. A nucleolar RNA helicase recognized by autoimmune antibodies from a patient with watermelon stomach disease. Nucleic Acids Res. 24:1996;1220-1224.
26. Valdez B. C., Hening D., Perlaky L., Busch R. K., Busch H. Cloning and characterization of Gu/RH-II binding protein. Biochem. Biophys. Res. Commun. 234:1997;335-340.
27. Valdez B. C., Perlaky L., Henning D., Saijo Y., Chan P. K., Busch H. Identification of the nuclear and nucleolar localisation signals of the protein p120: Interaction with translocation protein B23. J. Biol. Chem. 269:1994;23776-23783.
28. Venema J., Bousquet-Antonelli C., Gelugne J. P., Caizergues-Ferrer M., Tollervey D. Rok1p is a putative RNA helicase required for rRNA processing. Mol. Cell Biol. 17:1997;3398-3407.
29. Wassarman D. A., Steitz J. A. Alive with DEAD proteins. Nature (London). 349:1991;463-464.
30. Weaver P. L., Sun C., Chang T.-H. Dbp3p, a putative RNA helicase in Saccharomyces cerevisiae is required for efficient pre-rRNA processing predominantly at site A3. Mol. Cell Biol. 17:1997;1354-1365.
31. Whitehead C. M., Winkfein R. J., Fritzler M. J., Rattner J. B. ASE-1: A novel protein of the fibrillar centres of the nucleolus and nucleolus organizer region of mitotic chromosomes. Chromosoma. 104:1997;493-502.
32. Yan C., Melese T. Multiple regions of NSR1 are sufficient for accumulation of a fusion protein within the nucleolus. J. Biol. Chem. 123:1993;1081-1091.