Sustained and accelerating activity at two discrete sites generate epileptiform discharges in slices of piriform cortex

Journal of Neuroscience

Volumn 19, Issue 4, 1999, Pages 1294-1306

  Demir, Rezan ^a   Haberly, Lewis B ^a   Jackson, Meyer B ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

Disinhibition; Epilepsy; Neural circuitry; Olfactory cortex; Piriform cortex; Voltage imaging

Indexed keywords

COBALT; KYNURENIC ACID;

ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; ELECTRIC ACTIVITY; ELECTROSTIMULATION; EPILEPTIC DISCHARGE; EPILEPTOGENESIS; IMAGE ANALYSIS; LATENT PERIOD; MALE; MEMBRANE DEPOLARIZATION; MICROELECTRODE; NERVE CONDUCTION; NONHUMAN; OLFACTORY CORTEX; PRIORITY JOURNAL; PYRIFORM CORTEX; RAT;

EID: 0033558312     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.19-04-01294.1999     Document Type: Article

References (36)

1. Ayala GF, Dichter M, Gumnit RJ, Matsumoto H, Spencer WA (1973) Genesis of epileptic interjetai spikes. New knowledge of cortical feedback systems suggests a neurophysiological explanation of brief paroxysms. Brain Res 52:1-17.
2. a) in piriform cortex. J Neurosci 16:3862-3876.
3. Behan M, Haberly LB (1999) Intrinsic and efferent connections of the endopiriform nucleus in rat. J Comp Neurol, in press.
4. Behan M, Sachdev P, Haberly LB (1997) Intrinsic and efferent connections of the endopiriform nucleus that may contribute to epileptogenesis. Soc Neurosci Abstr 23:317.8.
5. Burwell RD, Witter MP, Amaral DG (1995) The perirhinal and postrhinal cortices of the rat: a review of the neuroanatomical literature and comparison with findings from the monkey brain. Hippocampus 5:390-408.
6. Cechetto DF, Saper CB (1987) Evidence for a viscerotopic sensory representation in the cortex and thalamus in the rat. J Comp Neurol 262:27-45.
7. Chien C-B, Pine J (1991) Voltage-sensitive dye recording of action potentials and synaptic potentials from sympathetic microcultures. Biophys J 60:697-711.
8. Colom LV, Saggau P (1994) Spontaneous interictal-like activity originates in multiple areas of the CA2-CA3 region of hippocampal slices. J Neurophysiol 71:1574-1585.
9. Crill WE (1996) Persistent sodium current in mammalian central neurons. Annu Rev Physiol 58:349-362.
10. Demir R, Haberly LB, Jackson MB (1997) Activity at two discreet sites in deep piriform cortex is required for epileptiform discharge. Soc Neurosci Abstr 23:836.9.
11. Demir R, Haberly LB, Jackson MB (1998) Voltage imaging of epileptiform activity in slices from rat piriform cortex: onset and propagation. J Neurophysiol 80:2723-2742.
12. Domroese ME, Haberly LB (1996) Dual origin of slow regenerative potentials in the endopiriform nucleus. Soc Neurosci Abstr 22:823.15.
13. Domroese ME, Behan M, Haberly LB (1997) Interneurons in the endopiriform nucleus and deep piriform cortex that may be involved in epileptogenesis. Soc Neurosci Abstr 23:316.14.
14. Grinvald A, Frostig RD, Lieke E, Hildesheim R (1988) Optical imaging of neuronal activity. Physiol Rev 68:1285-1366.
15. Haberly LB (1998) Olfactory Cortex. In: The synaptic organization of the brain (Shepherd GM, ed), pp 377-416. New York: Oxford UP.
16. Hoffman WH, Haberly LB (1989) Bursting induces persistent all-or-none EPSPs by an NMDA-dependent process in piriform cortex. J Neurosci 9:206-215.
17. Hoffman WH, Haberly LB (1991) Bursting-induced epileptiform EPSPs in slices of piriform cortex are generated by deep cells. J Neurosci 11:2021-2031.
18. Hoffman WH, Haberly LB (1993) Role of synaptic excitation in the generation of bursting-induced epileptiform potentials in the endopiriform nucleus and piriform cortex. J Neurophysiol 70:2550-2561.
19. Hoffman WH, Haberly LB (1996) Kindling-induced epileptiform potentials in piriform cortex slices originate in the underlying endopiriform nucleus. J Neurophysiol 76:1430-1438.
20. Huguenard JR (1996) Low-threshold calcium currents in central nervous system neurons. Annu Rev Physiol 58:329-348.
21. Jackson MB, Scharfman HE (1996) Positive feedback from hilar mossy cells to granule cells in the dentate gyrus revealed by voltage-sensitive dye and microelectrode recording. J Neurophysiol 76:601-616.
22. Johnston D, Brown TH (1986) Control theory applied to neural networks illuminates synaptic basis of interjetai epileptiform activity. Adv Neurol 44:263-274.
23. Klapstein GJ, Colmers WF (1997) Neuropeptide Y suppresses epileptiform activity in rat hippocampus in vitro. J Neurophysiol 78:1651-1661.
24. Llinás R, Sugimori M (1980a) Electrophysiological properties of in vitro Purkinje cell somata in mammalian cerebellar slices. J Physiol (Lond) 305:171-195.
25. Llinás R, Sugimori M (1980b) Electrophysiological properties of in vitro Purkinje cell dendrites in mammalian cerebellar slices. J Physiol (Lond) 305:197-213.
26. Magistretti J, de Curtis M (1998) Low-voltage-activated T-type calcium currents are differently expressed in superficial and deep layers of guinea pig piriform cortex. J Neurophysiol 79:808-816.
27. McIntyre DC, Kelly ME, Staines WA (1996) Efferent projections of the anterior perirhinal cortex of the rat. J Comp Neurol 369:302-318.
28. Paxinos G, Watson C (1998) The rat brain in stereotaxic coordinates, Ed 4. New York: Academic.
29. Stasheff SF, Anderson WW, Clark S, Wilson WA (1989) NMDA antagonists differentiate epileptogenesis from seizure expression in an in vitro model. Science 245:648-651.
30. Traub RD, Miles R (1991) Neuronal networks of the hippocampus. New York: Cambridge UP.
31. Traub RD, Miles R, Wong RKS (1989) Model of the origin of rhythmic population oscillations in the hippocampal slice. Science 243:1319-1325.
32. Tseng GF, Haberly LB (1989a) Deep neurons in piriform cortex. I. Morphology and synaptically evoked responses including a unique high-amplitude paired shock facilitation. J Neurophysiol 62:369-385.
33. Tseng GF, Haberly LB (1989b) Deep neurons in piriform cortex. II. Membrane properties that underlie unusual synaptic responses. J Neurophysiol 62:386-400.
34. Wong RKS, Traub RD, Miles R (1986) Cellular basis of neuronal synchrony in epilepsy. In: Basic mechanisms of the epilepsies (Delgado-Escueta AV, Ward AA, Woodbury DM, Porter RJ, eds), pp 583-592. New York: Raven.
35. Wu JY, Cohen LB (1993) Fast multisite optical measurements of membrane potential. In: Fluorescent and luminescent probes for biological activity (Mason WT, ed), pp 389-404. London: Academic.
36. Zucker RS (1989) Short-term synaptic plasticity. Annu Rev Neurosci 12:13-31.