메뉴 건너뛰기




Volumn 18, Issue 4, 1999, Pages 1038-1048

Structural basis for the specificity of the initiation of HIV-1 reverse transcription

Author keywords

AIDS; DNA polymerase; Reverse transcriptase; RNA; Structure

Indexed keywords

LYSINE TRANSFER RNA; RNA DIRECTED DNA POLYMERASE; VIRUS RNA;

EID: 0033558050     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/18.4.1038     Document Type: Article
Times cited : (106)

References (65)
  • 1
    • 0026578805 scopus 로고
    • Trp primer is required for efficient initiation of reverse transcription
    • Trp primer is required for efficient initiation of reverse transcription. J. Virol., 66, 2464-2472.
    • (1992) J. Virol. , vol.66 , pp. 2464-2472
    • Aiyar, A.1    Cobrinik, D.2    Ge, Z.3    Kung, H.J.4    Leis, J.5
  • 2
    • 0028123452 scopus 로고
    • A specific orientation of RNA secondary structure is required for initiation of reverse transcription
    • Aiyar, A., Ge, Z. and Leis, J. (1994) A specific orientation of RNA secondary structure is required for initiation of reverse transcription. J. Virol., 68, 611-618.
    • (1994) J. Virol. , vol.68 , pp. 611-618
    • Aiyar, A.1    Ge, Z.2    Leis, J.3
  • 3
    • 0031982415 scopus 로고    scopus 로고
    • Interaction of retroviral reverse transcriptase with template-primer duplexes during replication
    • Arts, E.J. and Le Grice, S.F.J. (1998) Interaction of retroviral reverse transcriptase with template-primer duplexes during replication. Prog. Nucleic Acids Res. Mol. Biol., 58, 339-393.
    • (1998) Prog. Nucleic Acids Res. Mol. Biol. , vol.58 , pp. 339-393
    • Arts, E.J.1    Le Grice, S.F.J.2
  • 4
    • 0029814780 scopus 로고    scopus 로고
    • Lys interactions inhibiting primer utilization by retroviral reverse transcriptases
    • Lys interactions inhibiting primer utilization by retroviral reverse transcriptases. Proc. Natl Acad. Sci. USA, 93, 10063-10068.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 10063-10068
    • Arts, E.J.1
  • 6
    • 0014964654 scopus 로고
    • Viral RNA-dependent DNA polymerase
    • Baltimore, D. (1970) Viral RNA-dependent DNA polymerase. Nature, 226, 1209-1211.
    • (1970) Nature , vol.226 , pp. 1209-1211
    • Baltimore, D.1
  • 7
    • 0027479628 scopus 로고
    • Functional sites in the 5′ region of human immunodeficiency virus type-1 RNA form defined structural domains
    • Baudin, F., Marquet, R., Isel, C., Darlix, J.L., Ehresmann, B. and Ehresmann, C. (1993) Functional sites in the 5′ region of human immunodeficiency virus type-1 RNA form defined structural domains. J. Mol. Biol., 229, 382-397.
    • (1993) J. Mol. Biol. , vol.229 , pp. 382-397
    • Baudin, F.1    Marquet, R.2    Isel, C.3    Darlix, J.L.4    Ehresmann, B.5    Ehresmann, C.6
  • 9
    • 0025963132 scopus 로고
    • Visualizing the higher order folding of a catalytic RNA molecule
    • Celander, D.W. and Cech, T.R. (1991) Visualizing the higher order folding of a catalytic RNA molecule. Science, 251, 401-407.
    • (1991) Science , vol.251 , pp. 401-407
    • Celander, D.W.1    Cech, T.R.2
  • 10
    • 0023732046 scopus 로고
    • A retroviral RNA secondary structure required for efficient initiation of reverse transcription
    • Cobrinik, D., Soskey, L. and Leis, J. (1988) A retroviral RNA secondary structure required for efficient initiation of reverse transcription. J. Virol., 62, 3622-3630.
    • (1988) J. Virol. , vol.62 , pp. 3622-3630
    • Cobrinik, D.1    Soskey, L.2    Leis, J.3
  • 11
    • 0022626913 scopus 로고
    • Isolation of a recombinant murine leukemia virus utilizing a new primer tRNA
    • Colicelli, J. and Goff, S.P. (1987) Isolation of a recombinant murine leukemia virus utilizing a new primer tRNA. J. Virol., 57, 37-45.
    • (1987) J. Virol. , vol.57 , pp. 37-45
    • Colicelli, J.1    Goff, S.P.2
  • 14
    • 0030786006 scopus 로고    scopus 로고
    • Protein-nucleic acid interactions and DNA conformation in a complex of human immunodeficiency virus type 1 reverse transcriptase with a double-stranded DNA template-primer
    • Ding, J., Hughes, S.H. and Arnold, E. (1997) Protein-nucleic acid interactions and DNA conformation in a complex of human immunodeficiency virus type 1 reverse transcriptase with a double-stranded DNA template-primer. Biopolymers, 44, 125-138.
    • (1997) Biopolymers , vol.44 , pp. 125-138
    • Ding, J.1    Hughes, S.H.2    Arnold, E.3
  • 15
    • 0032518398 scopus 로고    scopus 로고
    • Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 Å resolution
    • Doublié, S., Tabor, S., Long, A.M., Richardson, C.C. and Ellenberger, T. (1998) Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 Å resolution. Nature, 391, 251-258.
    • (1998) Nature , vol.391 , pp. 251-258
    • Doublié, S.1    Tabor, S.2    Long, A.M.3    Richardson, C.C.4    Ellenberger, T.5
  • 16
    • 0028924567 scopus 로고
    • Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors
    • Esnouf, R., Ren, J.S., Ross, C., Jones, Y., Stammers, D. and Stuart, D. (1995) Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors. Nature Struct. Biol., 2, 303-308.
    • (1995) Nature Struct. Biol. , vol.2 , pp. 303-308
    • Esnouf, R.1    Ren, J.S.2    Ross, C.3    Jones, Y.4    Stammers, D.5    Stuart, D.6
  • 19
    • 0018716671 scopus 로고
    • A detailed model of reverse transcription and tests of crucial aspects
    • Gilboa, E., Mitra, S.W., Goff, S. and Baltimore, D. (1979) A detailed model of reverse transcription and tests of crucial aspects. Cell, 18, 93-100.
    • (1979) Cell , vol.18 , pp. 93-100
    • Gilboa, E.1    Mitra, S.W.2    Goff, S.3    Baltimore, D.4
  • 20
    • 0028945841 scopus 로고
    • HIV-1 reverse transcriptase-associated RNase H cleaves RNA/RNA in arrested complexes: Implications for the mechanism by which RNase H discriminates beween RNA/RNA and RNA/DNA
    • Götte, M., Fackler, S., Hermann, T., Perola, E., Cellai, L., Gross, H.J., Le Grice, S.F.J. and Heumann, H. (1995) HIV-1 reverse transcriptase-associated RNase H cleaves RNA/RNA in arrested complexes: Implications for the mechanism by which RNase H discriminates beween RNA/RNA and RNA/DNA. EMBO J., 14, 833-841.
    • (1995) EMBO J. , vol.14 , pp. 833-841
    • Götte, M.1    Fackler, S.2    Hermann, T.3    Perola, E.4    Cellai, L.5    Gross, H.J.6    Le Grice, S.F.J.7    Heumann, H.8
  • 21
    • 0032573488 scopus 로고    scopus 로고
    • Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: Implications for drug resistance
    • Huang, H., Chopra, R., Verdine, G.L. and Harrison, S.C. (1998) Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance. Science, 282, 1669-1675.
    • (1998) Science , vol.282 , pp. 1669-1675
    • Huang, H.1    Chopra, R.2    Verdine, G.L.3    Harrison, S.C.4
  • 23
    • 0027331556 scopus 로고
    • Lys modulate primer/template loop-loop interaction in the initiation complex of HIV-1 reverse transcription
    • Lys modulate primer/template loop-loop interaction in the initiation complex of HIV-1 reverse transcription. J. Biol. Chem., 268, 25269-25272.
    • (1993) J. Biol. Chem. , vol.268 , pp. 25269-25272
    • Isel, C.1    Marquet, R.2    Keith, G.3    Ehresmann, C.4    Ehresmann, B.5
  • 27
    • 0027318776 scopus 로고
    • Crystal structure of human immunodeficiency virus type-1 reverse transcriptase complexed with double-stranded DNA at 3.0 Å resolution shows bent DNA
    • Jacobo-Molina, A. et al. (1993) Crystal structure of human immunodeficiency virus type-1 reverse transcriptase complexed with double-stranded DNA at 3.0 Å resolution shows bent DNA. Proc. Natl Acad. Sci. USA, 90, 6320-6324.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 6320-6324
    • Jacobo-Molina, A.1
  • 28
    • 0028774179 scopus 로고
    • Comparison of three different crystal forms shows HIV-1 reverse transcriptase displays an internal swivel motion
    • Jager, J., Smerdon, S.J., Wang, J.M., Boisvert, D.C. and Steitz, T.A. (1994) Comparison of three different crystal forms shows HIV-1 reverse transcriptase displays an internal swivel motion. Structure, 2, 869-876.
    • (1994) Structure , vol.2 , pp. 869-876
    • Jager, J.1    Smerdon, S.J.2    Wang, J.M.3    Boisvert, D.C.4    Steitz, T.A.5
  • 29
    • 0000356656 scopus 로고
    • A graphic model building and refinement system for macromolecules
    • Jones, T.A. (1978) A graphic model building and refinement system for macromolecules. J. Appl. Crystallogr., 11, 268-272.
    • (1978) J. Appl. Crystallogr. , vol.11 , pp. 268-272
    • Jones, T.A.1
  • 31
    • 0032518524 scopus 로고    scopus 로고
    • Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal
    • Kiefer, J.R., Mao, C. Braman, J.C. and Beese, L.S. (1998) Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal. Nature, 391, 304-307.
    • (1998) Nature , vol.391 , pp. 304-307
    • Kiefer, J.R.1    Mao, C.2    Braman, J.C.3    Beese, L.S.4
  • 32
    • 0026693137 scopus 로고
    • Crystal structure at 3.5 Å resolution of HIV-1 reverse transcriptase complexed with an inhibitor
    • Kohlstaedt, L.A., Wang, J., Friedman, J.M., Rice, P.A. and Steitz, T.A. (1992) Crystal structure at 3.5 Å resolution of HIV-1 reverse transcriptase complexed with an inhibitor. Science, 256, 1783-1790.
    • (1992) Science , vol.256 , pp. 1783-1790
    • Kohlstaedt, L.A.1    Wang, J.2    Friedman, J.M.3    Rice, P.A.4    Steitz, T.A.5
  • 33
    • 0001720577 scopus 로고
    • A restrained-parameter thermal-factor refinement procedure
    • Konnert, J.H. and Hendrickson, W.A. (1980) A restrained-parameter thermal-factor refinement procedure. Acta Crystallogr., 36, 344-350.
    • (1980) Acta Crystallogr. , vol.36 , pp. 344-350
    • Konnert, J.H.1    Hendrickson, W.A.2
  • 34
    • 0030449991 scopus 로고    scopus 로고
    • Binding and kinetic properties of HIV-1 reverse transcriptase markedly differ during initiation and elongation of reverse transcription
    • Lanchy, J.M., Ehresmann, C., Le Grice, S.F.J. Ehresmann, B. and Marquet, R. (1996) Binding and kinetic properties of HIV-1 reverse transcriptase markedly differ during initiation and elongation of reverse transcription. EMRO J., 15, 7178-7187.
    • (1996) EMRO J. , vol.15 , pp. 7178-7187
    • Lanchy, J.M.1    Ehresmann, C.2    Le Grice, S.F.J.3    Ehresmann, B.4    Marquet, R.5
  • 35
    • 0024359787 scopus 로고
    • Defining the inside and outside of a catalytic RNA molecule
    • Latham, J.A. and Cech, T.R. (1989) Defining the inside and outside of a catalytic RNA molecule. Science, 245, 276-282.
    • (1989) Science , vol.245 , pp. 276-282
    • Latham, J.A.1    Cech, T.R.2
  • 36
    • 0025191211 scopus 로고
    • Rapid purification of homodimer and heterodimer HIV-1 reverse transcriptase by metal chelate aftinity chromatography
    • Le Grice, S.F.J. and Grueninger-Leitch, F. (1990) Rapid purification of homodimer and heterodimer HIV-1 reverse transcriptase by metal chelate aftinity chromatography. Eur. J. Biochem., 187, 307-314.
    • (1990) Eur. J. Biochem. , vol.187 , pp. 307-314
    • Le Grice, S.F.J.1    Grueninger-Leitch, F.2
  • 37
    • 0028122546 scopus 로고
    • Effects of alterations of primer-binding site sequences on human immunodeficiency virus type 1 replication
    • Li, X.G., Mak, J., Arts, E.J., Gu, Z.X., Kleiman, L., Wainberg, M.A. and Parniak, M.A. (1994) Effects of alterations of primer-binding site sequences on human immunodeficiency virus type 1 replication. J. Virol., 68, 6198-6206.
    • (1994) J. Virol. , vol.68 , pp. 6198-6206
    • Li, X.G.1    Mak, J.2    Arts, E.J.3    Gu, Z.X.4    Kleiman, L.5    Wainberg, M.A.6    Parniak, M.A.7
  • 39
    • 0030795935 scopus 로고    scopus 로고
    • The importance of the A-rich loop in human immunodeficiency virus type 1 reverse transcription and infectivity
    • Liang, C., Li, X., Rong, L., Inouye, P., Quan, Y., Kleiman, L. and Wainberg, M.A. (1997) The importance of the A-rich loop in human immunodeficiency virus type 1 reverse transcription and infectivity. J. Virol., 71, 5750-5757.
    • (1997) J. Virol. , vol.71 , pp. 5750-5757
    • Liang, C.1    Li, X.2    Rong, L.3    Inouye, P.4    Quan, Y.5    Kleiman, L.6    Wainberg, M.A.7
  • 40
    • 0027360074 scopus 로고
    • Mutated primer binding sites interacting with different tRNAs allow efficient murine leukemia virus replication
    • Lund, A.H., Duch, M., Lovmand, J., Jørgensen, P. and Pedersen, F.S. (1993) Mutated primer binding sites interacting with different tRNAs allow efficient murine leukemia virus replication. J. Virol., 67, 7125-7130.
    • (1993) J. Virol. , vol.67 , pp. 7125-7130
    • Lund, A.H.1    Duch, M.2    Lovmand, J.3    Jørgensen, P.4    Pedersen, F.S.5
  • 41
    • 0031027095 scopus 로고    scopus 로고
    • Complementation of a primer binding site-impaired murine leukemia virus-derived retroviral vector by a genetically engineered tRNA-like primer
    • Lund, A.H., Duch, M., Lovmand, J., Jørgensen, P. and Pedersen, F.S. (1997) Complementation of a primer binding site-impaired murine leukemia virus-derived retroviral vector by a genetically engineered tRNA-like primer. J. Virol., 71, 1191-1195.
    • (1997) J. Virol. , vol.71 , pp. 1191-1195
    • Lund, A.H.1    Duch, M.2    Lovmand, J.3    Jørgensen, P.4    Pedersen, F.S.5
  • 42
    • 0030812830 scopus 로고    scopus 로고
    • Primer tRNAs for reverse transcription
    • Mak, J. and Kleiman, L. (1997) Primer tRNAs for reverse transcription. J. Virol., 71, 8087-8095.
    • (1997) J. Virol. , vol.71 , pp. 8087-8095
    • Mak, J.1    Kleiman, L.2
  • 44
    • 0028500393 scopus 로고
    • DRAWNA: A program for drawing schematic views of nucleic acids
    • Massire, C., Gaspin, C. and Westhof, E. (1994) DRAWNA: a program for drawing schematic views of nucleic acids. J. Mol. Graph., 12, 201-207.
    • (1994) J. Mol. Graph. , vol.12 , pp. 201-207
    • Massire, C.1    Gaspin, C.2    Westhof, E.3
  • 45
    • 0027225211 scopus 로고
    • Hydroxyl radical footprint analysis of human immunodeficiency virus reverse transcriptase-template-primer complexes
    • Metzger, W., Hermann, T., Schatz, O., Le Grice, S.F.J. and Heumann, H. (1993) Hydroxyl radical footprint analysis of human immunodeficiency virus reverse transcriptase-template-primer complexes. Proc. Natl Acad. Sci. USA, 90, 5909-5913.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 5909-5913
    • Metzger, W.1    Hermann, T.2    Schatz, O.3    Le Grice, S.F.J.4    Heumann, H.5
  • 46
    • 0029061471 scopus 로고
    • Lys to reverse transcriptase from human immunodeficiency virus type 1
    • Lys to reverse transcriptase from human immunodeficiency virus type 1. EMBO J., 14, 2679-2687.
    • (1995) EMBO J. , vol.14 , pp. 2679-2687
    • Mishima, Y.A.1    Steitz, J.A.2
  • 47
    • 0001884540 scopus 로고    scopus 로고
    • Probing RNA structure and function in solution
    • Simons, R.W. and Grunberg-Manago, M. (eds), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • Moine, H., Ehresmann, B., Ehresmann, C. and Romby, P. (1997) Probing RNA structure and function in solution. In Simons, R.W. and Grunberg-Manago, M. (eds), RNA Structure and Function. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 77-115.
    • (1997) RNA Structure and Function , pp. 77-115
    • Moine, H.1    Ehresmann, B.2    Ehresmann, C.3    Romby, P.4
  • 48
    • 0028301674 scopus 로고
    • GAAA tetraloop and conserved bulge stabilize tertiary structure of a group 1 intron domain
    • Murphy, F.L. and Cech, T.R. (1994) GAAA tetraloop and conserved bulge stabilize tertiary structure of a group 1 intron domain. J. Mol. Biol., 236, 49-63.
    • (1994) J. Mol. Biol. , vol.236 , pp. 49-63
    • Murphy, F.L.1    Cech, T.R.2
  • 49
    • 0030606301 scopus 로고    scopus 로고
    • HIV-1 reverse transcriptase discriminates against non-self tRNA primers
    • Oude Essink, B.B., Das, A.T. and Berkhout, B. (1996) HIV-1 reverse transcriptase discriminates against non-self tRNA primers. J. Mol. Biol., 264, 243-254.
    • (1996) J. Mol. Biol. , vol.264 , pp. 243-254
    • Oude Essink, B.B.1    Das, A.T.2    Berkhout, B.3
  • 50
    • 0027996464 scopus 로고
    • Mutational analysis of the bipartite dimer linkage structure of HIV-1 genomic RNA
    • Paillart, J.C., Marquet, R., Skripkin, E., Ehresmann, B. and Ehresmann, C. (1994) Mutational analysis of the bipartite dimer linkage structure of HIV-1 genomic RNA. J. Biol. Chem., 269, 27486-27493.
    • (1994) J. Biol. Chem. , vol.269 , pp. 27486-27493
    • Paillart, J.C.1    Marquet, R.2    Skripkin, E.3    Ehresmann, B.4    Ehresmann, C.5
  • 51
    • 0019051754 scopus 로고
    • Chemical probes for higher-order structure in RNA
    • Peattie, D.A. and Gilbert, W. (1980) Chemical probes for higher-order structure in RNA. Proc. Natl Acad. Sci. USA, 77, 4679-4682.
    • (1980) Proc. Natl Acad. Sci. USA , vol.77 , pp. 4679-4682
    • Peattie, D.A.1    Gilbert, W.2
  • 52
    • 0011152255 scopus 로고
    • Molecular modeling with the PS300: A new generation graphics display system
    • Pflugrath, J.W., Saper, M.A. and Quiocho, F.A. (1983) Molecular modeling with the PS300: a new generation graphics display system. J. Mol. Graph., 1, 53-54.
    • (1983) J. Mol. Graph. , vol.1 , pp. 53-54
    • Pflugrath, J.W.1    Saper, M.A.2    Quiocho, F.A.3
  • 53
    • 0021755764 scopus 로고
    • Solvent accessible surface area and excluded volume in proteins
    • Richmond, T.J. (1984) Solvent accessible surface area and excluded volume in proteins. J. Mol. Biol., 178, 63-89.
    • (1984) J. Mol. Biol. , vol.178 , pp. 63-89
    • Richmond, T.J.1
  • 54
    • 0030930760 scopus 로고    scopus 로고
    • Crystal structures of human DNA polymerase β complexed with gapped and nicked DNA: Evidence for an induced fit mechanism
    • Sawaya, M.R., Prasad, R., Wilson, S.H., Kraut, J. and Pelletier, H. (1997) Crystal structures of human DNA polymerase β complexed with gapped and nicked DNA: Evidence for an induced fit mechanism. Biochemistry, 36, 11205-11215.
    • (1997) Biochemistry , vol.36 , pp. 11205-11215
    • Sawaya, M.R.1    Prasad, R.2    Wilson, S.H.3    Kraut, J.4    Pelletier, H.5
  • 55
    • 0029909551 scopus 로고    scopus 로고
    • The 16S rRNA binding site of Thermus thermophilus ribosomal protein S15: Comparison with Escherichia coli S15, minimum site and structure
    • Serganov, A.A., Masquida, B., Westhof, E., Cachia, C., Portier, C., Garber, M., Ehresmann, B. and Ehresmann, C. (1996) The 16S rRNA binding site of Thermus thermophilus ribosomal protein S15: Comparison with Escherichia coli S15, minimum site and structure. RNA, 2, 1124-1138.
    • (1996) RNA , vol.2 , pp. 1124-1138
    • Serganov, A.A.1    Masquida, B.2    Westhof, E.3    Cachia, C.4    Portier, C.5    Garber, M.6    Ehresmann, B.7    Ehresmann, C.8
  • 57
    • 0014964695 scopus 로고
    • RNA-dependent DNA polymerase in virions of Rous sarcoma virus
    • Temin, H.M. and Mizutani, S. (1970) RNA-dependent DNA polymerase in virions of Rous sarcoma virus. Nature, 226, 1211-1213.
    • (1970) Nature , vol.226 , pp. 1211-1213
    • Temin, H.M.1    Mizutani, S.2
  • 60
    • 0001320146 scopus 로고
    • Modelling the three-dimensional structure of ribonucleic acids
    • Westhof, E. (1993) Modelling the three-dimensional structure of ribonucleic acids. J. Mol. Struct., 286, 203-210.
    • (1993) J. Mol. Struct. , vol.286 , pp. 203-210
    • Westhof, E.1
  • 61
    • 0021879256 scopus 로고
    • Crystallographic refinement of yeast aspartic acid transfer RNA
    • Westhof, E., Dumas, P. and Moras, D. (1985) Crystallographic refinement of yeast aspartic acid transfer RNA. J. Mol. Biol., 184, 119-145.
    • (1985) J. Mol. Biol. , vol.184 , pp. 119-145
    • Westhof, E.1    Dumas, P.2    Moras, D.3
  • 62
    • 0029133873 scopus 로고
    • Replication of avian leukosis viruses with mutations at the primer binding site: Use of alternative tRNAs as primers
    • Whitcomb, J.M., Ortiz-Conde, B.A. and Hughes, S.H. (1995) Replication of avian leukosis viruses with mutations at the primer binding site: use of alternative tRNAs as primers. J. Virol., 69, 6228-6238.
    • (1995) J. Virol. , vol.69 , pp. 6228-6238
    • Whitcomb, J.M.1    Ortiz-Conde, B.A.2    Hughes, S.H.3
  • 63
    • 0029056438 scopus 로고
    • An expanded model of replicating human immunodeficiency virus reverse transcriptase
    • Wöhrl, B.M., Tantillo, C., Arnold, E. and Le Grice, S.F.J. (1995) An expanded model of replicating human immunodeficiency virus reverse transcriptase. Biochemistry, 34, 5343-5350.
    • (1995) Biochemistry , vol.34 , pp. 5343-5350
    • Wöhrl, B.M.1    Tantillo, C.2    Arnold, E.3    Le Grice, S.F.J.4
  • 64
    • 0030589458 scopus 로고    scopus 로고
    • Nucleotide sequences within the U5 region of the viral RNA genome are the major determinants for an human immunodeficiency virus type 1 to maintain a primer binding site complementary to tRNA (His)
    • Zhang, Z., Kang, S.M., LeBlanc, A., Hajduk, S.L. and Morrow, C.D. (1996) Nucleotide sequences within the U5 region of the viral RNA genome are the major determinants for an human immunodeficiency virus type 1 to maintain a primer binding site complementary to tRNA (His). Virology, 226, 306-317.
    • (1996) Virology , vol.226 , pp. 306-317
    • Zhang, Z.1    Kang, S.M.2    LeBlanc, A.3    Hajduk, S.L.4    Morrow, C.D.5
  • 65
    • 0031922810 scopus 로고    scopus 로고
    • Genetic analysis of the U5-PBS of a novel HIV-1 reveals multiple interactions between the tRNA and RNA genome required for initiation of reverse transcription
    • Zhang, Z.J., Kang, S.M., Li, Y. and Morrow, C.D. (1998) Genetic analysis of the U5-PBS of a novel HIV-1 reveals multiple interactions between the tRNA and RNA genome required for initiation of reverse transcription. RNA, 4, 394-406.
    • (1998) RNA , vol.4 , pp. 394-406
    • Zhang, Z.J.1    Kang, S.M.2    Li, Y.3    Morrow, C.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.