Glycosaminoglycans treatment increases IGF-I muscle levels and counteracts motor neuron death: A novel nonanticoagulant action

Journal of Neuroscience Research

Volumn 55, Issue 4, 1999, Pages 496-505

  Losa, Matteo ^a   Vergani, Letizia ^a   Lesma, Elena ^a   Rossoni, Giuseppe ^a   Di Giulio, Anna Maria ^a   Vercelli, Alessandro ^b   Torsello, Antonio ^a   Muller, Eugenio E ^a   Gorio, Alfredo ^a,c  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

^c Lab Res Pharmacol Neurodeg D   (Italy)

Author keywords

Heparin; IGF I; Motor neuron survival; Muscle atrophy; Muscle reinnervation

Indexed keywords

GLYCOSAMINOGLYCAN; HEPARIN; HEPARIN LYASE; MESSENGER RNA; NERVE GROWTH FACTOR; SOMATOMEDIN BINDING PROTEIN; SOMATOMEDIN C;

ANIMAL CELL; ANIMAL TISSUE; ANTICOAGULATION; ARTICLE; CELL COUNT; CELL LOSS; CELL SURVIVAL; CONTROLLED STUDY; DRUG EFFECT; EXTENSOR DIGITORUM LONGUS MUSCLE; MOTONEURON; MUSCLE ATROPHY; MUSCLE CELL; MUSCLE DENERVATION; MUSCLE LEVEL; MUSCLE MASS; MUSCLE REINNERVATION; NERVE CELL DEGENERATION; NERVE CELL LESION; NERVE CELL NECROSIS; NERVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; SCIATIC NERVE; TREATMENT OUTCOME;

EID: 0033558043     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19990215)55:4<496::AID-JNR9>3.0.CO;2-6     Document Type: Article

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