A physical, transcript, and deletion map of chromosome region 12p12.3 Flanked by ETV6 and CDKN1B: Hypermethylation of the LRP6 CpG island in two leukemia patients with hemizygous del(12p)

Genomics

Volumn 56, Issue 1, 1999, Pages 40-50

  Baens, Mathijs ^a   Wlodarska, Iwona ^a   Corveleyn, Anniek ^a   Hoornaert, Inge ^a   Hagemeijer, Anne ^a   Marynen, Peter ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CONTIG; DNA; NUCLEOTIDE;

ARTICLE; CHROMOSOME 12P; CHROMOSOME DELETION; CLINICAL ARTICLE; CPG ISLAND; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE; GENE INACTIVATION; GENE SILENCING; GENE STRUCTURE; HETEROZYGOSITY LOSS; HUMAN; LEUKEMIA; MALE; METHYLATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PSEUDOGENE; PULSED FIELD GEL ELECTROPHORESIS; TUMOR SUPPRESSOR GENE;

EID: 0033557787     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1998.5685     Document Type: Article

References (53)

1. Altschul S. F., Madden T. L., Schaffer A. A., Zhang J., Zhang Z., Miller W., Lipman D. J. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs. Nucleic Acids Res. 25:1997;3389-3402.
2. Baens M., Aerssens J., Van Zand K., Van Den Berghe H., Marynen P. Isolation and regional assignment of human chromosome 12p cDNAs. Genomics. 29:1995;44-52.
3. Baens M., Peeters P., Guo C., Aerssens J., Marynen P. Genomic organisation of TEL: The human ETS-variant gene 6 (ETV6). Genome Res. 6:1996;404-413.
4. Batova A., Diccianni M. B., Yu J. C., Nobori T., Link M. P., Pullen J., Yu A. L. Frequent and selective methylation ofp15p15p16. Cancer Res. 57:1997;832-836.
5. Baylin S. B., Herman J. G., Graff J. R., Vertino P. M., Issa J. P. Alterations in DNA methylation: A fundamental aspect of neoplasia. Adv. Cancer Res. 72:1998;141-196.
6. Brown S. D., Twells R. C. J., Hey P. J., Cox R. D., Levy E. R., Soderman A. R., Metzker M. L., Caskey C. T., Todd J. A., Hess J. F. Isolation and characterization of LRP6, a novel member of the low density lipoprotein receptor gene family. Biochem. Biophys. Res. Commun. 248:1998;879-888.
7. Buijs A., Sherr S., Van Baal S., Van Bezouw S., Van der Plas D., Van Kessel A. G., Riegman P., Deprez R. L., Zwarthoff E., Hagemeijer A., Grosveld G. Translocation (12;22) (p13;q11) in myeloproliferative disorders results in fusion of the ETS-likeTELMN1. Oncogene. 10:1995;1511-1519.
8. Kip1. Nat. Med. 3:1997;227-230.
9. Dal Cin P., Drochmans A., Moerman P., Van Den Berghe H. Isochromosome 12p in mediastinal germ cell tumor. Cancer Genet. Cytogenet. 42:1989;243-251.
10. Golub T. R., Barker G. F., Bohlander S. K., Hiebert S. W., Ward D. C., Bray-Ward P., Morgan E., Raimondi S. C., Rowley J. D., Gilliland D. G. Fusion of theTELAML1. Proc. Natl. Acad. Sci. USA. 92:1995;4917-4921.
11. Golub T. R., Barker G. F., Lovett M., Gilliland D. G. Fusion of PDGF receptor β to a noveletstel, Cell. 77:1994;307-316.
12. Hatta Y., Takeuchi S., Yokota J., Koeffler H. P. Ovarian cancer has frequent loss of heterozygosity at chromosome 12p12.3-13.1 (region ofTELKip1. Br. J. Cancer. 75:1997;1256-1262.
13. Herman J. G., Graff J. R., Myöhänen S., Nelkin B. D., Baylin S. B. Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands. Proc. Natl. Acad. Sci. USA. 93:1996;9821-9826.
14. Hey P., Twells R. C. J., Phillips M. S., Nakagawa Y., Brown S. D., Kawaguchi Y., Cox R., Xie G., Dugan V., Hammond H., Metzker M. L., Todd J. A., Hess J. F. Cloning of a novel member of the low-density lipoprotein receptor family. Gene. 216:1998;103-111.
15. Hiltunen M. O., Alhonen L., Koistinaho J., Myöhänen S., Pääkkönen M., Marin S., Kosma V. M., Jänne J. Hypermethylation of theAPCPolyposis coli. Int. J. Cancer. 70:1997;644-648.
16. Hoornaert I., Marynen P., Baens M. CREBL2,ETV6CDKN1B. Genomics. 51:1998;154-157.
17. Issa J. P. J., Baylin S. B., Herman J. G. DNA methylation changes in hematologic malignancies: Biologic and clinical implications. Leukemia. 11:1997;S7-S11.
18. Johansson B., Mertens F., Mitelman F. Cytogenetic deletion maps of hematologic neoplasms: Circumstantial evidence for tumor suppressor loci. Genes Chromosomes Cancer. 8:1993;205-218.
19. Kanai Y., Ushijima S., Hui A. M., Ochiai A., Tsuda H., Sakamoto M., Hirohashi S. The E-cadherin gene is silenced by CpG methylation in human hepatocellular carcinomas. Int. J. Cancer. 71:1997;355-359.
20. Knezevich S. R., McFadden D. E., Tao W., Lim J. F., Sorensen P. H. B. A novelETV6-NTRK3. Nat. Genet. 18:1998;184-187.
21. Krauter K., Montgomery K., Yoon S. J., LeBlanc-Straceski J., Renault B., Marondel I., Herdman V., Cupelli L., Banks A., Lieman J., Menninger J., Bray-Ward P., Nadkami P., Weissenbach J., Le Paslier D., Rigault P., Chumakov I., Cohen D., Miller P., Ward D., Kucherlapati R. A second-generation YAC contig map of human chromosome 12. Nature. 377:1995;321-333.
22. Kucherlapati R., Marynen P., Turc-Carel C. Report of the Fourth International Workshop on Human Chromosome 12 Mapping 1997 held on April 27-29, 1997-Nice, France. Cytogenet. Cell Genet. 78:1997;81-92.
23. Lacronique V., Boureux A., Valle V. D., Poirel H., Quang C. T., Mauchauffe M., Berthou C., Lessard M., Berger R., Ghysdael J., Bernard O. A. A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia. Science. 278:1997;1309-1312.
24. Li J., Yen C., Liaw D., Podsypanina K., Bose S., Wang S. I., Puc J., Miliaresis C., Rodgers L., McCombie R., Bigner S. H., Giovanella B. C., Ittmann M., Tycko B., Hibshoosh H., Wigler M. H., Parsons R. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science. 275:1997;1943-1947.
25. Liaw D., Marsh D. J., Li J., Dahia P. L. M., Wang S. I., Zheng Z. M., Bose S., Call K. M., Tsou H. C., Peacocke M., Eng C., Parsons R. Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome. Nat. Genet. 16:1997;64-67.
26. Loda M., Cukor B., Tam S. W., Lavin P., Fiorentino M., Draetta G. F., Jessup J. M., Pagano M. Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas. Nat. Med. 3:1997;231-234.
27. Merlo A., Herman J. G., Mao L., Lee D. J., Gabrielson E., Burger P. C., Baylin S. B., Sidransky D. 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressorp16/CDKN2/MTS1. Nat. Med. 1:1997;686-692.
28. Montgomery K. T., LeBlanc J. M., Tsai P., McNinch J. S., Ward D. C., de Jong P. J., Kucherlapati R., Krauter K. S. Characterization of two chromosome 12 cosmid libraries and development of STSs from cosmids mapped by FISH. Genomics. 17:1993;682-693.
29. KIP1. Blood. 86:1995;1924-1930.
30. Ng M. H. L., Chung Y. F., Lo K. W., Wickham N. W. R., Lee J. C. K., Huang D. P. Frequent hypermethylation ofp16p15. Blood. 89:1997;2500-2506.
31. Nizetic D., Zehetner G., Monaco A. P., Gellen L., Young B. D., Lehrach H. Construction, arraying and high-density screening of large insert libraries of human chromosome X and 21: Their potential use as reference libraries. Proc. Natl. Acad. Sci. USA. 88:1991;3233-3237.
32. Papadopoulos P., Ridge S. A., Boucher C. A., Stocking C., Wiedemann L. M. The novel activation of ABL by fusion to an ets-related gene, TEL. Cancer Res. 55:1995;34-38.
33. Parra I., Windle B. High resolution visual mapping of stretched DNA by fluorescent hybridisation. Nat. Genet. 5:1993;17-21.
34. Peeters P., Wlodarska I., Baens M., Criel A., Selleslag D., Hagemeijer A., Van Den Berghe H., Marynen P. Fusion ofETV6MDS1/EVI1. Cancer Res. 57:1997a;564-569.
35. Peeters P., Raynaud S. D., Cools J., Wlodarska I., Grosgeorge J., Philip P., Monpoux F., Van Rompaey L., Baens M., Van Den Berghe H., Marynen P. Fusion ofTEL,ETV6JAK2. Blood. 90:1997b;2535-2540.
36. Kip1. Nat. Med. 3:1997;222-225.
37. Raynaud S., Cavé H., Baens M., Bastard C., Cacheux V., Grosgeorge J., Guidal-Giroux C., Guo C. Y., Vilmer E., Marynen P., Grandchamp B. The 12;21 translocation involvingTELTEL. Blood. 87:1996;2891-2899.
38. Riley J., Butler R., Ogilvie D., Finniear R., Jenner D., Powell S., Anand R., Smith J. C., Markham A.F. A novel, rapid method for the isolation of terminal sequences from yeast artificial chromosome (YAC) clones. Nucleic Acids Res. 18:1990;2887-2890.
39. Romana S. P., Le Coniat M., Poirel H., Marynen P., Bernard O. A., Berger R. Deletion of the short arm of chromosome 12 is a secondary event in acute lymphoblastic leukemia with t(12;21). Leukemia. 10:1996;167-170.
40. Romana S. P., Mauchauffe M., Le Coniat M., Chumakov I., Le Paslier D., Berger R., Bernard O. A. The t(12;21) of acute lymphoblastic leukemia results in a tel-AML1 gene fusion. Blood. 85:1995;3662-3670.
41. Sambrook J., Fritsch E., Maniatis T. Molecular Cloning: A Laboratory Manual. 1989;Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
42. Sato Y., Suto Y., Pietenpol J., Golub T. R., Gilliland D. G., Davis E. M., Le Beau M. M., Roberts J. M., Vogelstein B., Rowley J. D., Bohlander S. K. TELKIP1. Blood. 86:1995;1525-1533.
43. Schuler G. D., Boguski M. S., Stewart E. A., Stein L. D., Gyapay G., Rice K., White R. E., Rodriguez Tome P., Aggarwal A., Bajorek E., Bentolila S., Birren B. B., Butler A., Castle A. B., Chiannikulchai N., Chu A., Clee C., Cowles S., Day P. J., Dibling T., Drouot N., Dunham I., Duprat S., East C., Hudson T. J. A gene map of the human genome. Science. 274:1996;540-546.
44. Southgate J., Proffitt J., Roberts P., Smith B., Selby P. Loss of cyclin-dependent kinase inhibitor genes and chromosome 9 karyotypic abnormalities in human bladder cancer cell lines. Br. J. Cancer. 72:1995;1214-1218.
45. Spirin K. S., Simpson J. F., Takeuchi S., Kawamata N., Miller C. W., Koeffler H. P. p27/Kip1 mutation found in breast cancer. Cancer Res. 56:1996;2400-2404.
46. Steck P. A., Pershouse M. A., Jasser S. A., Yung W. K. A., Lin H., Ligon A. H., Langford L. A., Baumgard M. L., Hattier T., Davis T., Frye C., Hu R., Swedlund B., Teng D. H. F., Tavtigian S. V. Identification of a candidate tumour suppressor gene,MMAC1, Nat. Genet. 15:1997;356-362.
47. Stegmaier K., Takeuchi S., Golub T. R., Bohlander S. K., Bartram C. R., Koeffler H. P., Gilliland D. G. Mutational analysis of the candidate tumor suppressor genesTELKIP1. Cancer Res. 56:1996;1413-1417.
48. Suto Y., Sato Y., Smith S. D., Rowley J. D., Bohlander S. K. A t(6;12)(q23;p13) results in the fusion of ETV6 to a novel gene, STL, in a B-cell ALL cell line. Genes Chromosomes Cancer. 18:1997;254-268.
49. Takeuchi S., Mori N., Koike M., Slater J., Park S., Miller C. W., Miyoshi I., Koeffler H. P. Frequent loss of heterozygosity in region of theKIP1. Cancer Res. 56:1996;738-740.
50. Watanabe T. K., Shimizu F., Nagata M., Takaichi A., Fujiwara T., Nakamura Y., Takahashi E., Hirai Y. Cloning, expression pattern and mapping to 12p13.2 → p13.1 of CLAPS3, a gene encoding a novel clathrin-adaptor small chain. Cytogenet. Cell Genet. 73:1996;214-217.
51. Wlodarska I., Baens M., Peeters P., Aerssens J., Mecucci C., Brock P., Marynen P., Van Den Berghe H. Biallelic alterations of bothETV6CDKN1B. Cancer Res. 56:1996a;2655-2661.
52. Wlodarska I., Marynen P., La Starza R., Mecucci C., Van Den Berghe H. The ETV6, CDKN1B and D12S178 loci are involved in a segment commonly deleted in various 12p aberrations in different hematological malignancies. Cytogenet. Cell Genet. 72:1996b;229-235.
53. Zhang Y., Lin S. C. Molecular characterization of the cyclin-dependent kinase inhibitor p27 promoter. Biochim. Biophys. Acta Gene Struct. Expression. 1353:1997;307-317.