메뉴 건너뛰기




Volumn 19, Issue 4, 1999, Pages 1335-1344

Suppression of postischemic hippocampal nerve growth factor expression by a c-fos antisense oligodeoxynucleotide

Author keywords

Antisense DNA; C fos; Drug target validation; Experimental cerebral ischemia; Gene function analysis; Gene regulation; Immediate early genes; Intracerebroventricular delivery; Neurotrophin; NGF; Oligodeoxynucleotide; Stroke; Transfection

Indexed keywords

ACTIN; ANTISENSE OLIGODEOXYNUCLEOTIDE; BIOTIN; MESSENGER RNA; NERVE GROWTH FACTOR; NEUROTROPHIN 3; PROTEIN C FOS;

EID: 0033557658     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.19-04-01335.1999     Document Type: Article
Times cited : (49)

References (58)
  • 1
    • 0345313998 scopus 로고
    • Cellular uptake and anti-HIV activity of oligonucleotides and their analogs
    • Erickson RP, des Izant JG, eds, New York: Raven
    • Agrawal S, Sarin PS, Zamecnik M, Zamecnik PC (1992) Cellular uptake and anti-HIV activity of oligonucleotides and their analogs. In: Gene regulation: biology of antisense RNA and DNA (Erickson RP, des Izant JG, eds), pp 273-228. New York: Raven.
    • (1992) Gene Regulation: Biology of Antisense RNA and DNA , pp. 273-1228
    • Agrawal, S.1    Sarin, P.S.2    Zamecnik, M.3    Zamecnik, P.C.4
  • 2
    • 0029834603 scopus 로고    scopus 로고
    • Immediate early gene expression in response to cerebral ischemia: Friend or foe?
    • Akins PT, Liu PK, Hsu CY (1996) Immediate early gene expression in response to cerebral ischemia: friend or foe? Stroke 27:1682-1687.
    • (1996) Stroke , vol.27 , pp. 1682-1687
    • Akins, P.T.1    Liu, P.K.2    Hsu, C.Y.3
  • 3
    • 0027283310 scopus 로고
    • Expression of c-fos and c-jun family genes after focal cerebral ischemia
    • An G, Lin T-N, Liu J-S, Xue J-J, He Y-Y, Hsu CY (1993) Expression of c-fos and c-jun family genes after focal cerebral ischemia. Ann Neurol 33:457-464.
    • (1993) Ann Neurol , vol.33 , pp. 457-464
    • An, G.1    Lin, T.-N.2    Liu, J.-S.3    Xue, J.-J.4    He, Y.-Y.5    Hsu, C.Y.6
  • 4
    • 0026497249 scopus 로고
    • Antisense oligonucleotide eliminates in vivo expression of c-fos in mammalian brain
    • Chiasson BJ, Hooper ML, Murphy PR, Robertson HA (1992) Antisense oligonucleotide eliminates in vivo expression of c-fos in mammalian brain. Eur J Pharmacol 227:451-453.
    • (1992) Eur J Pharmacol , vol.227 , pp. 451-453
    • Chiasson, B.J.1    Hooper, M.L.2    Murphy, P.R.3    Robertson, H.A.4
  • 6
    • 0028986604 scopus 로고
    • Sleep-waking changes after c-fos antisense injections in the medial preoptic area
    • Cirelli C, Pompeiano M, Tononi G (1995a) Sleep-waking changes after c-fos antisense injections in the medial preoptic area. NeuroReport 6:801-805.
    • (1995) Neuroreport , vol.6 , pp. 801-805
    • Cirelli, C.1    Pompeiano, M.2    Tononi, G.3
  • 7
    • 0028867610 scopus 로고
    • In vivo antisense approaches to the role of immediate early gene expression in the brain
    • Cirelli C, Pompeiano M, Tononi G (1995b) In vivo antisense approaches to the role of immediate early gene expression in the brain. Regul Pept 59:1551-1621.
    • (1995) Regul Pept , vol.59 , pp. 1551-1621
    • Cirelli, C.1    Pompeiano, M.2    Tononi, G.3
  • 8
    • 0026645859 scopus 로고
    • Expression and involvement of c-fos and c-jun protooncogenes in programmed cell death induced by growth factor deprivation in lymphoid cell lines
    • Colotta F, Polentarutti N, Sironi M, Mantovani A (1992) Expression and involvement of c-fos and c-jun protooncogenes in programmed cell death induced by growth factor deprivation in lymphoid cell lines. J Biol Chem 267:18278-18283.
    • (1992) J Biol Chem , vol.267 , pp. 18278-18283
    • Colotta, F.1    Polentarutti, N.2    Sironi, M.3    Mantovani, A.4
  • 9
    • 0021247951 scopus 로고
    • Spiral and cellular fos protein: A comparative analysis
    • Curran T, Miller AD, Zokas L, Verma IM (1984) Spiral and cellular Fos protein: a comparative analysis. Cell 36:259-268.
    • (1984) Cell , vol.36 , pp. 259-268
    • Curran, T.1    Miller, A.D.2    Zokas, L.3    Verma, I.M.4
  • 10
    • 0026472565 scopus 로고
    • Differential regulation of the nerve growth factor and brain-derived neurotrophic factor genes in l929 mouse fibroblasts
    • D'Mello SR, Jiang C, Lamberti C, Martin SC, Heinrich G (1992) Differential regulation of the nerve growth factor and brain-derived neurotrophic factor genes in L929 mouse fibroblasts. J Neurosci Res 33:519-526.
    • (1992) J Neurosci Res , vol.33 , pp. 519-526
    • D'Mello, S.R.1    Jiang, C.2    Lamberti, C.3    Martin, S.C.4    Heinrich, G.5
  • 11
    • 0028609906 scopus 로고
    • c-fos antisense reduces expression of Krox 24 in rat caudate and neocortex
    • Dragunow M, Tse C, Glass M, Lawlor P (1994) c-fos antisense reduces expression of Krox 24 in rat caudate and neocortex. Cell Mol Neurobiol 14:395-405.
    • (1994) Cell Mol Neurobiol , vol.14 , pp. 395-405
    • Dragunow, M.1    Tse, C.2    Glass, M.3    Lawlor, P.4
  • 12
    • 0023687772 scopus 로고
    • Expression of c-fos antisense RNA inhibits the differentiation of F9 cells to parietal endoderm
    • Edwards SA, Rundell YK, Adamson ED (1988) Expression of c-fos antisense RNA inhibits the differentiation of F9 cells to parietal endoderm. Dev Biol 129:91-102.
    • (1988) Dev Biol , vol.129 , pp. 91-102
    • Edwards, S.A.1    Rundell, Y.K.2    Adamson, E.D.3
  • 15
    • 0028217132 scopus 로고
    • Requirement for BDNF in activity-dependent survival of cortical neurons
    • Ghosh A, Carnahan J, Greenberg ME, (1994) Requirement for BDNF in activity-dependent survival of cortical neurons. Science 263:1618-1623.
    • (1994) Science , vol.263 , pp. 1618-1623
    • Ghosh, A.1    Carnahan, J.2    Greenberg, M.E.3
  • 17
    • 0030944373 scopus 로고    scopus 로고
    • Gene expression and apoptosis in the spinal cord neurons after peripheral nerve damage
    • Gu ZZ, Pan C, Cui JK, Klebec M, Shenaq S, Liu PK (1997) Gene expression and apoptosis in the spinal cord neurons after peripheral nerve damage. Neurochem Int 30:417-426.
    • (1997) Neurochem Int , vol.30 , pp. 417-426
    • Gu, Z.Z.1    Pan, C.2    Cui, J.K.3    Klebec, M.4    Shenaq, S.5    Liu, P.K.6
  • 18
    • 0023771685 scopus 로고
    • c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities
    • Halazonetis TD, Georgopoulos K, Greenberg ME, Leder P (1988) c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities. Cell 55:917-924.
    • (1988) Cell , vol.55 , pp. 917-924
    • Halazonetis, T.D.1    Georgopoulos, K.2    Greenberg, M.E.3    Leder, P.4
  • 19
    • 0024394332 scopus 로고
    • Function of neurotrophic factors in the adult and aging brain and their possible use in the treatment of neurodegenerative diseases
    • Hefti F, Hartikka J, Knusel B (1989) Function of neurotrophic factors in the adult and aging brain and their possible use in the treatment of neurodegenerative diseases. Neurobiol Aging 10:515-533.
    • (1989) Neurobiol Aging , vol.10 , pp. 515-533
    • Hefti, F.1    Hartikka, J.2    Knusel, B.3
  • 20
    • 0027310376 scopus 로고
    • c-fos antisense in the nucleus accumbens blocks the locomotor stimulant action of cocaine
    • Heilig M, Engel JA, Soderpalm B (1993) c-fos antisense in the nucleus accumbens blocks the locomotor stimulant action of cocaine. Eur J Pharmacol 236:339-340.
    • (1993) Eur J Pharmacol , vol.236 , pp. 339-340
    • Heilig, M.1    Engel, J.A.2    Soderpalm, B.3
  • 22
    • 0001597247 scopus 로고
    • Inducible production of c-fos antisense RNA inhibits 3T3 cell proliferation
    • Holt JT, Gopal TV, Moulton AD, Nienhuis AW (1986) Inducible production of c-fos antisense RNA inhibits 3T3 cell proliferation. Proc Natl Acad Sci USA 83:4794-4798.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 4794-4798
    • Holt, J.T.1    Gopal, T.V.2    Moulton, A.D.3    Nienhuis, A.W.4
  • 23
    • 0028150874 scopus 로고
    • Infusion into the brain of an antisense oligonucleotide to the immediate-early gene c-fos suppresses production of fos and produces a behavioral effect
    • Hooper ML, Chiasson BJ, Robertson HA (1994) Infusion into the brain of an antisense oligonucleotide to the immediate-early gene c-fos suppresses production of fos and produces a behavioral effect. Neuroscience 63:917-924.
    • (1994) Neuroscience , vol.63 , pp. 917-924
    • Hooper, M.L.1    Chiasson, B.J.2    Robertson, H.A.3
  • 24
    • 0024253769 scopus 로고
    • Growth factors regulate transin gene expression by c-fos-dependent and c-fos-independent pathways
    • Kerr LD, Holt JT, Matrisian LM (1988) Growth factors regulate transin gene expression by c-fos-dependent and c-fos-independent pathways. Science 242:1424-1427.
    • (1988) Science , vol.242 , pp. 1424-1427
    • Kerr, L.D.1    Holt, J.T.2    Matrisian, L.M.3
  • 25
    • 0344019795 scopus 로고
    • Terminal deoxynucleotidyl transferase
    • San Francisco: Freeman
    • Kornberg A (1980) Terminal deoxynucleotidyl transferase. In: DNA replication, pp 225-229. San Francisco: Freeman.
    • (1980) DNA Replication , pp. 225-229
    • Kornberg, A.1
  • 26
    • 0022347794 scopus 로고
    • Induction of the protooncogene fos by nerve growth factor
    • Kruijer W, Schubert D, Verma IM (1985) Induction of the protooncogene fos by nerve growth factor. Proc Natl Acad Sci USA 82:7330-7334.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 7330-7334
    • Kruijer, W.1    Schubert, D.2    Verma, I.M.3
  • 27
    • 0024009355 scopus 로고
    • Constitutive expression of c-fos antisense RNA blocks c-fos gene induction by interferon and by phorbol ester and reduces c-myc expression in F9 embryonal carcinoma cells
    • Levi BZ, Ozato K (1988) Constitutive expression of c-fos antisense RNA blocks c-fos gene induction by interferon and by phorbol ester and reduces c-myc expression in F9 embryonal carcinoma cells. Genes Dev 2:554-566.
    • (1988) Genes Dev , vol.2 , pp. 554-566
    • Levi, B.Z.1    Ozato, K.2
  • 28
    • 0024208990 scopus 로고
    • c-fos antisense RNA blocks expression of c-fos gene in F9 embryonal carcinoma cells
    • Levi BZ, Kasik JW, Ozato K (1988) c-fos antisense RNA blocks expression of c-fos gene in F9 embryonal carcinoma cells. Cell Differ Dev 258:95-101.
    • (1988) Cell Differ Dev , vol.258 , pp. 95-101
    • Levi, B.Z.1    Kasik, J.W.2    Ozato, K.3
  • 29
    • 0026599302 scopus 로고
    • Differential regulation of mRNAs for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 in the adult rat brain following cerebral ischemia and hypoglycemic coma
    • Lindvall O, Ernfors P, Bengzon J, Kokaia Z, Smith ML, Siesjo BK, Persson H (1992) Differential regulation of mRNAs for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 in the adult rat brain following cerebral ischemia and hypoglycemic coma. Proc Natl Acad Sci USA 89:648-652.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 648-652
    • Lindvall, O.1    Ernfors, P.2    Bengzon, J.3    Kokaia, Z.4    Smith, M.L.5    Siesjo, B.K.6    Persson, H.7
  • 30
    • 0027265878 scopus 로고
    • Enhanced expression in the α-type DNA polymerase genes reduces AZT-cytotoxicity in hamster tr5 cells
    • Liu PK (1993) Enhanced expression in the α-type DNA polymerase genes reduces AZT-cytotoxicity in hamster tr5 cells. Somatic Cell Mol Genet 19:211-220.
    • (1993) Somatic Cell Mol Genet , vol.19 , pp. 211-220
    • Liu, P.K.1
  • 31
    • 0028170006 scopus 로고
    • Suppression of ischemia-induced fos expression and AP-1 activity by an antisense oligodeoxynucleotide to c-fos mRNA
    • Liu PK, Salminen A, He YY, Jiang MH, Xue JJ, Liu JS, Hsu CY (1994) Suppression of ischemia-induced Fos expression and AP-1 activity by an antisense oligodeoxynucleotide to c-fos mRNA. Ann Neurol 36:566-576.
    • (1994) Ann Neurol , vol.36 , pp. 566-576
    • Liu, P.K.1    Salminen, A.2    He, Y.Y.3    Jiang, M.H.4    Xue, J.J.5    Liu, J.S.6    Hsu, C.Y.7
  • 32
    • 0025217198 scopus 로고
    • Direct cloning of leucine zipper proteins: Jun binds cooperatively to the CRE with CRE-BP1
    • Macgregor PF, Abate C, Curran T (1990) Direct cloning of leucine zipper proteins: Jun binds cooperatively to the CRE with CRE-BP1. Oncogene 5:451-458.
    • (1990) Oncogene , vol.5 , pp. 451-458
    • Macgregor, P.F.1    Abate, C.2    Curran, T.3
  • 34
    • 0023669349 scopus 로고
    • Antisense RNA to the c-fos gene: Restoration of density-dependent growth arrest in a transformed cell line
    • Mercola D, Rundell A, Westwick J, Edwards SA (1987) Antisense RNA to the c-fos gene: restoration of density-dependent growth arrest in a transformed cell line. Biochem Biophys Res Commun 147:288-294.
    • (1987) Biochem Biophys Res Commun , vol.147 , pp. 288-294
    • Mercola, D.1    Rundell, A.2    Westwick, J.3    Edwards, S.A.4
  • 35
    • 0002468854 scopus 로고
    • Antisense oligonucleotides in the context of modern molecular drug discovery and development
    • Crooke ET, Lebleu B, eds, Boca Raton, FL: CRC
    • Mirabelli CK, Crooke ST (1993) Antisense oligonucleotides in the context of modern molecular drug discovery and development. In: Antisense research and applications (Crooke ET, Lebleu B, eds), pp 7-35. Boca Raton, FL: CRC.
    • (1993) Antisense Research and Applications , pp. 7-35
    • Mirabelli, C.K.1    Crooke, S.T.2
  • 36
    • 0023125528 scopus 로고
    • Antisense RNA of protooncogene c-fos blocks renewed growth of quiescent 3T3 cells
    • Nishikura K, Murray HM (1987) Antisense RNA of protooncogene c-fos blocks renewed growth of quiescent 3T3 cells. Mol Cell Biol 7:637-649.
    • (1987) Mol Cell Biol , vol.7 , pp. 637-649
    • Nishikura, K.1    Murray, H.M.2
  • 37
    • 0024990331 scopus 로고
    • Wide spread expression of BDNF but not NT3 by target areas of basal forebrain cholinergic neurons
    • Phillips HS, Hains JM, Laramee GR, Rosenthal A, Winslow JW (1990) Wide spread expression of BDNF but not NT3 by target areas of basal forebrain cholinergic neurons. Science 250:290-294.
    • (1990) Science , vol.250 , pp. 290-294
    • Phillips, H.S.1    Hains, J.M.2    Laramee, G.R.3    Rosenthal, A.4    Winslow, J.W.5
  • 39
    • 0029951903 scopus 로고    scopus 로고
    • Antisense oligodeoxynucleotide attenuates in vivo expression of c-fos in the paraventricular hypothalamic nucleus of the rat brain
    • Quercia S, Chang SL (1996) Antisense oligodeoxynucleotide attenuates in vivo expression of c-fos in the paraventricular hypothalamic nucleus of the rat brain. Neurosci Lett 209:89-92.
    • (1996) Neurosci Lett , vol.209 , pp. 89-92
    • Quercia, S.1    Chang, S.L.2
  • 40
    • 0030668245 scopus 로고    scopus 로고
    • Differentiation of engrafted multipotent neural progenitors towards replacement of missing granule neurons in meander tail cerebellum may help determine the locus of mutant gene action
    • Rosario CM, Yandava BD, Kosaras B, Zurakowski D, Sidman RL, Snyder EY (1997) Differentiation of engrafted multipotent neural progenitors towards replacement of missing granule neurons in meander tail cerebellum may help determine the locus of mutant gene action. Development 124:4213-4224.
    • (1997) Development , vol.124 , pp. 4213-4224
    • Rosario, C.M.1    Yandava, B.D.2    Kosaras, B.3    Zurakowski, D.4    Sidman, R.L.5    Snyder, E.Y.6
  • 41
    • 0032562704 scopus 로고    scopus 로고
    • Early activation of c-Jun N-terminal kinase and p38 kinase regulate cell survival in response to tumor necrosis factor alpha
    • Roulston A, Reinhard C, Amiri P, Williams LT (1998) Early activation of c-Jun N-terminal kinase and p38 kinase regulate cell survival in response to tumor necrosis factor alpha. J Biol Chem 273:10232-10239.
    • (1998) J Biol Chem , vol.273 , pp. 10232-10239
    • Roulston, A.1    Reinhard, C.2    Amiri, P.3    Williams, L.T.4
  • 42
    • 0027300977 scopus 로고
    • Expression of c-fos protein in brain: Metabolic mapping at the cellular level
    • Sagar SM (1993) Expression of c-fos protein in brain: metabolic mapping at the cellular level. Ann Neurol 33:437-438.
    • (1993) Ann Neurol , vol.33 , pp. 437-438
    • Sagar, S.M.1
  • 43
    • 0023891990 scopus 로고
    • Expression of c-fos protein in brain: Metabolic mapping at the cellular level
    • Sagar SM, Sharp FR, Curran T (1988) Expression of c-fos protein in brain: metabolic mapping at the cellular level. Science 240:1328-1331.
    • (1988) Science , vol.240 , pp. 1328-1331
    • Sagar, S.M.1    Sharp, F.R.2    Curran, T.3
  • 44
    • 0029119638 scopus 로고
    • Alteration of transcription factor binding activities in the ischemic rat brain
    • Salminen A, Liu PK, Hsu CY (1995) Alteration of transcription factor binding activities in the ischemic rat brain. Biochem Biophys Res Commun 212:939-944.
    • (1995) Biochem Biophys Res Commun , vol.212 , pp. 939-944
    • Salminen, A.1    Liu, P.K.2    Hsu, C.Y.3
  • 45
    • 0025872121 scopus 로고
    • Ribozyme-mediated cleavage of c-fos mRNA reduces gene expression of DNA synthesis enzymes and metallothionein
    • Scanlon KJ, Jiao L, Funato T, Wang W, Tine T, Rossi JJ, Kashani-Sabet M (1991) Ribozyme-mediated cleavage of c-fos mRNA reduces gene expression of DNA synthesis enzymes and metallothionein. Proc Natl Acad Sci USA 88:10591-10595.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 10591-10595
    • Scanlon, K.J.1    Jiao, L.2    Funato, T.3    Wang, W.4    Tine, T.5    Rossi, J.J.6    Kashani-Sabet, M.7
  • 46
    • 0028631458 scopus 로고
    • The role of Jun transcription factor expression and phosphorylation in neuronal differentiation, neuronal cell death, and plastic adaptations in vivo
    • Schlingensiepen KH, Wollnik F, Kunst M, Schlingensiepen R, Herdegen T, Brysch W (1994) The role of Jun transcription factor expression and phosphorylation in neuronal differentiation, neuronal cell death, and plastic adaptations in vivo. Cell Mol Neurobiol 14:487-505.
    • (1994) Cell Mol Neurobiol , vol.14 , pp. 487-505
    • Schlingensiepen, K.H.1    Wollnik, F.2    Kunst, M.3    Schlingensiepen, R.4    Herdegen, T.5    Brysch, W.6
  • 47
    • 0023819405 scopus 로고
    • Requirement for fos gene expression in the transcriptional activation of collagenase by other oncogene and phorbol esters
    • Schönthal A, Herrlic P, Rahmsdorf HJ, Ponta H (1988) Requirement for fos gene expression in the transcriptional activation of collagenase by other oncogene and phorbol esters. Cell 54: 325-334.
    • (1988) Cell , vol.54 , pp. 325-334
    • Schönthal, A.1    Herrlic, P.2    Rahmsdorf, H.J.3    Ponta, H.4
  • 48
    • 0028136829 scopus 로고
    • The sense of antisense fos oligonucleotides
    • Sharp FR (1994) The sense of antisense fos oligonucleotides. Ann Neurol 36:566-576.
    • (1994) Ann Neurol , vol.36 , pp. 566-576
    • Sharp, F.R.1
  • 49
    • 0025065439 scopus 로고
    • The NMDA receptor mediates cortical induction of fos and fos-related antigens following cortical injury
    • Sharp JW, Sagar SM, Hisanaga K, Jasper P, Sharp FR (1991) The NMDA receptor mediates cortical induction of fos and fos-related antigens following cortical injury. Exp Neurol 109:323-332.
    • (1991) Exp Neurol , vol.109 , pp. 323-332
    • Sharp, J.W.1    Sagar, S.M.2    Hisanaga, K.3    Jasper, P.4    Sharp, F.R.5
  • 50
    • 0025270328 scopus 로고
    • Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB
    • Sheng M, McFadden G, Greenberg ME (1990) Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB. Neuron 4:571-582.
    • (1990) Neuron , vol.4 , pp. 571-582
    • Sheng, M.1    McFadden, G.2    Greenberg, M.E.3
  • 51
    • 0027972156 scopus 로고
    • Anti-AP-1 activity of all-trans retinoic acid in glomerular mesangial cells
    • Simonson MS (1994) Anti-AP-1 activity of all-trans retinoic acid in glomerular mesangial cells. Am J Physiol 267:F805-815.
    • (1994) Am J Physiol , vol.267
    • Simonson, M.S.1
  • 52
    • 0028238769 scopus 로고
    • Functions of the neurotrophins during nervous system development: What the knockdowns are teaching us
    • Snider WD (1994) Functions of the neurotrophins during nervous system development: what the knockdowns are teaching us. Cell 77:627-638.
    • (1994) Cell , vol.77 , pp. 627-638
    • Snider, W.D.1
  • 53
    • 0030636214 scopus 로고    scopus 로고
    • Potential of neural "stem-like" cells for gene therapy and repair of the degenerating central nervous system
    • Snyder EY, Park KI, Flax JD, Liu S, Rosario CM, Yandava BD, Aurora S (1997) Potential of neural "stem-like" cells for gene therapy and repair of the degenerating central nervous system. Adv Neurol 72:121-132.
    • (1997) Adv Neurol , vol.72 , pp. 121-132
    • Snyder, E.Y.1    Park, K.I.2    Flax, J.D.3    Liu, S.4    Rosario, C.M.5    Yandava, B.D.6    Aurora, S.7
  • 54
    • 0025071211 scopus 로고
    • Localization of brain-derived neurotrophic factor mRNA to neurons in the brain by in situ hybridization
    • Wetmore C, Ernfors P, Persson H, Olson L (1990) Localization of brain-derived neurotrophic factor mRNA to neurons in the brain by in situ hybridization. Exp Neurol 109:141-152.
    • (1990) Exp Neurol , vol.109 , pp. 141-152
    • Wetmore, C.1    Ernfors, P.2    Persson, H.3    Olson, L.4
  • 55
    • 0027298897 scopus 로고
    • Stability, clearance, and disposition of intraventricularly administered oligodeoxynucleotides: Implications for therapeutic application within the central nervous system
    • Whitesell L, Geselowitz D, Chavany C, Fahmy B, Walbridge S, Alger JR, Neckers LM (1993) Stability, clearance, and disposition of intraventricularly administered oligodeoxynucleotides: implications for therapeutic application within the central nervous system. Proc Natl Acad Sci USA 90:4665-4669.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 4665-4669
    • Whitesell, L.1    Geselowitz, D.2    Chavany, C.3    Fahmy, B.4    Walbridge, S.5    Alger, J.R.6    Neckers, L.M.7
  • 57
    • 0029953122 scopus 로고    scopus 로고
    • Angitensin II regulation of tyrosine hydroxylase gene expression in the neuronal cultures of normotensive and spontaneously hypertensive rats
    • Yu K, Lu D, Rowland NE, Raizada MK (1996) Angitensin II regulation of tyrosine hydroxylase gene expression in the neuronal cultures of normotensive and spontaneously hypertensive rats. Endocrinology 137:3566-3576.
    • (1996) Endocrinology , vol.137 , pp. 3566-3576
    • Yu, K.1    Lu, D.2    Rowland, N.E.3    Raizada, M.K.4
  • 58
    • 0023947867 scopus 로고
    • Structural and functional analysis of the promoter region of the nerve growth factor gene
    • Zheng M, Heinrich G (1988) Structural and functional analysis of the promoter region of the nerve growth factor gene. Brain Res 427: 133-140.
    • (1988) Brain Res , vol.427 , pp. 133-140
    • Zheng, M.1    Heinrich, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.