Previous uptake of apoptotic neutrophils or ligation of integrin receptors downmodulates the ability of macrophages to ingest apoptotic neutrophils

Blood

Volumn 93, Issue 4, 1999, Pages 1406-1412

  Erwig, Lars Peter ^a,b   Gordon, Sharon ^a   Walsh, Garry M ^a   Rees, Andrew J ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

INTEGRIN RECEPTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; IMMUNOREGULATION; MACROPHAGE; MALE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

EID: 0033557563     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v93.4.1406.404k10_1406_1412     Document Type: Article

References (39)

1. Unanue ER: Studies in listeriosis show the strong symbiosis between the innate cellular system and the T-cell response. Immunol Rev 158:11, 1997
2. Duvall E, Wyllie AH, Morris RG: Macrophage recognition of cells undergoing programmed cell death (apoptosis). Immunology 56:351, 1985
3. Savill J, Hogg N, Ren Y, Haslett C: Thrombospondin cooperates with CD36 and the vitronectin receptor in macrophage recognition of neutrophils undergoing apoptosis. J Clin Invest 90:1513, 1992
4. Savill J, Dransfield I, Hogg N, Haslett C: Vitronectin receptor-mediated phagocytosis of cell undergoing apoptosis. Nature 343:170, 1990
5. Fadok VA, Voelker DR, Campbell PA, Cohen JJ, Bratton DL, Henson PM: Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J Immunol 148:2207, 1992
6. Fadok VA, Savill JS, Haslett C, Bratton DL, Doherty DE, Campbell PA, Henson PM Henson: Different populations of macrophages use either the vitronectin receptor or the phosphatidylserine receptor to recognize and remove apoptotic cells. J Immunol 149:4029, 1992
7. Platt N, Suzuki H, Kurihara Y, Kodama T, Gordon S: Role for the class A macrophage scavenger receptor in the phagocytosis of apoptotic thymocytes in vitro. Proc Natl Acad Sci USA 93:12456, 1996
8. Flora PK, Gregory CD: Recognition of apoptotic cells by human macrophages: Inhibition by a monocyte/macrophage-specific monoclonal antibody. Eur J Immunol 24:2625, 1994
9. Devitt A, Moffatt OD, Raykundalia C, Capra JD, Simmons DL, Gregory CD: Human CD14 mediates recognition and phagocytosis of apoptotic cells. Nature 392:505, 1998
10. Pradhan D, Krahling S, Williamson P, Schlegel RA: Multiple systems for recognition of apoptotic lymphocytes by macrophages. Mol Biol Cell 8:767, 1997
11. Ramprasad MP, Terpstra V, Kondratenko N, Quehenberger O, Steinberg D: Cell surface expression of mouse macrosialin and human CD68 and their role as macropahge receptors for oxidized low density lipoprotein. Proc Natl Acad Sci USA 93:14833, 1996
12. Sambrano GR, Steinberg D: Recognition of oxidatively damaged and apoptotic cells by and oxidized low density lipoprotein receptor on mouse peritoneal macrophages: Role of membrane phosphatidylserine. Proc Natl Acad Sci USA 28:1396, 1995
13. Morris RG, Hargreaves AD Duvall E, Wyllie AH: Hormone-induced cell death. 2. Surface changes in thymocytes undergoing apoptosis. Am J Pathol 115:426, 1984
14. Walsh GM, Williamson ML, Symon FA, Willars GB, Wardlaw AJ: Ligation of CD69 induces apoptosis and cell death in human eosinophils cultured with granulocyte-macrophage colony-stimulating factor. Blood 87:2815, 1996
15. Savill J, Smith J, Sarraf C, Ren Y, Abbott F, Rees A: Glomerular mesangial cells and inflammatory macrophages ingest neutrophils undergoing apoptosis. Kidney Int 42:924, 1992
16. Meagher LC, Savill JS, Baker A, Fuller RW Haslett C: Phagocytosis of apoptotic neutrophils does not induce macrophage release of thromboxane B2. J Leukoc Biol 52:269, 1992
17. Fadok VA, Bratton DL, Konowal A, Freed PW, Westcott JY, Henson PM: Macrophages that have ingested apoptotic cells in vitro inhibit profinflammatory cytokine production through autocrine/ paracrine mechanisms involving TGF-beta, PGE2, and PAF. J Clin Invest 101:890, 1998
18. Lake FR, Noble PW, Henson PM, Riches DW: Functional switching of macrophage responses to tumor necrosis factor-alpha (TNF alpha) by interferons. Implications for the pleiotropic activities of TNF alpha. J Clin Invest 93:1661, 1994
19. Bellingan GJ, Caldwell H, Howie SE, Dransfield I, Haslett C: In vivo fate of the inflammatory macrophage during the resolution of inflammation: Inflammatory macrophages do not die locally, but emigrate to the draining lymph nodes. J Immunol 157:2577, 1996
20. Tam FW, Smith J, Karkar AM, Pusey CD, Rees AJ: Interleukin-4 ameliorates experimental glomerulonephritis and up-regulates glomerular gene expression of IL-1 decoy receptor. Kidney Int 52:1224, 1997
21. Helfrich MH, Nesbitt SA, Horton MA: Integrins on rat osteoclasts: Characterization of two monoclonal antibodies (F4 and F11) to rat beta 3. J Bone Miner Res 7:345, 1992
22. Noble PW, Henson PM, Lucas C, Mora-Worms M, Carre PC Riches DW: Transforming growth factor-beta primes macrophages to express inflammatory gene products in response to particulate stimuli by an autocrine/paracrine mechanism. J Immunol 151:979, 1993
23. Savill JS, Wyllie AH, Henson JE, Walport MJ, Henson PM, Haslett: Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages. J Clin Invest 83:865, 1989
24. Savill JS, Henson PM, Haslett C: Phagocytosis of aged human neutrophils by macrophages is mediated by a novel "charge-sensitive" recognition mechanism. J Clin Invest 84:1518, 1989
25. Ren Y, Savill J: Proinflammatory cytokines potentiate thrombospondin-mediated phagocytosis of neutrophils undergoing apoptosis. J Immunol 154:2366, 1995
26. Bonder CS, Dickensheets HL, Finlay-Jones JJ, Donnelly RP, Hart PH: Involvement of the IL-2 receptor gamma-chain (gammac) in the control by IL-4 of human monocyte and macrophage proinflammatory mediator production. J Immunol 160:4048, 1998
27. Fadok VA, Laszlo DJ, Noble PW, Weinstein L, Riches DW, Henson PM: Particle digestibility is required for induction of the phosphatidylserine recognition mechanism used by murine macrophages to phagocytose apoptotic cells. J Immunol 151:4274, 1993
28. Erwig L-P, Rees AJ: Interleukins 4, 6 and 10 have different effects on rat macrophages. J Am Soc Nephrol 8:471a. 1997 (abstr)
29. Shankar G, Davison I, Helfrich MH, Mason WT, Horton MA: Integrin receptor-mediated mobilisation of intranuclear calcium in rat osteoclasts. J Cell Sci 105:61, 1993
30. Henson PM, Riches DW: Modulation of macrophage maturation by cytokines and lipid mediators: A potential role in resolution of pulmonary inflammation. Ann N Y Acad Sci 725:298, 1994
31. Ogasawara J, Watanabe-Fukunaga R, Adachi M, Matsuzawa A, Kasugai T, Kitamura Y, Itoh N, Suda T, Nagata S: Lethal effect of the anti-Fas antibody in mice. Nature 364:806, 1993
32. Johnson RJ: The glomeular response to injury: Progression or resolution? Kidney Int 45:1769, 1994
33. Blystone SD, Graham IL, Lindberg FP, Brown EJ: Integrin of αvβ3 differentially regulates adhesive and phagocytic functions of the fibronectin receptor α5β1. J Cell Biol 127:1129, 1994
34. Blystone SD, Lindberg FP, LaFlamme SE, Brown EJ: Integrin β3 cytoplasmic tail is necessary and sufficient for regulation of α5β1 phagocytosis by αvβ3 and integrin-associated protein. J Cell Biol 130:745, 1995
35. Diaz-Gonzalez F, Forsyth J, Steiner B, Ginsberg MH: Transdominant inhibition of integrin function. Mol Biol Cell 7:1939, 1996
36. Fenczik CA, Sethi T, Ramos JW, Hughes PE, Ginsberg MH: Complementation of dominant suppression implicates CD98 in integrin activation. Nature 390:81, 1997
37. Ylänne J, Huuskonen J, O'Toole TE, Ginsberg MH, Virtanen I, Gahmberg CG: Mutation of the cytoplasmic domain of the integrin β3 subunit. J Biol Chem 270:9550, 1995
38. 1. J Immunol 160:3562, 1998
39. Hart SP, Dougherty GJ, Haslett C, Dransfield I: CD44 regulates phagocytosis of apoptotic neutrophil granulocytes, but not apoptotic lymphocytes, by human macrophages. J Immunol 159:919, 1997