-
2
-
-
0014288929
-
Pharmacological effects in animals and normal human subjects of the diuretic amiloride hydrochloride (MK-870)
-
Baba W. I., Lant A. F., Smith A. J., Townshend M. M., Wilson G. M. Pharmacological effects in animals and normal human subjects of the diuretic amiloride hydrochloride (MK-870). Clin. Pharmacol. Ther. 9:1968;318-327.
-
(1968)
Clin. Pharmacol. Ther.
, vol.9
, pp. 318-327
-
-
Baba, W.I.1
Lant, A.F.2
Smith, A.J.3
Townshend, M.M.4
Wilson, G.M.5
-
4
-
-
0020557160
-
Experimental interstitial renal fibrosis in rats: Nephritis induced byN
-
Barrett M. C., Cashman S. J., Moss J. Experimental interstitial renal fibrosis in rats: Nephritis induced byN. Br. J. Exp. Pathol. 64:1983;425-435.
-
(1983)
Br. J. Exp. Pathol.
, vol.64
, pp. 425-435
-
-
Barrett, M.C.1
Cashman, S.J.2
Moss, J.3
-
5
-
-
0027421895
-
Effect of microsomal enzyme modulators onN
-
Beers K. W., Nicoll D. W., Anestis D. K., Brown P. I., Rankin G. O. Effect of microsomal enzyme modulators onN. Toxicology. 84:1993;141-155.
-
(1993)
Toxicology
, vol.84
, pp. 141-155
-
-
Beers, K.W.1
Nicoll, D.W.2
Anestis, D.K.3
Brown, P.I.4
Rankin, G.O.5
-
7
-
-
0015926539
-
Effects of phenobarbital and 3-methylcholanthrene on substrate specificity of rat liver microsomal UDP-glucuronyltransferase
-
Bock K. W., Frohling W., Remmer H., Rexer B. Effects of phenobarbital and 3-methylcholanthrene on substrate specificity of rat liver microsomal UDP-glucuronyltransferase. Biochim. Biophys. Acta. 327:1973;46-56.
-
(1973)
Biochim. Biophys. Acta
, vol.327
, pp. 46-56
-
-
Bock, K.W.1
Frohling, W.2
Remmer, H.3
Rexer, B.4
-
8
-
-
0017184389
-
A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein dye binding
-
Bradford M. M. A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Anal. Biochem. 72:1976;248-254.
-
(1976)
Anal. Biochem.
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
9
-
-
0023254046
-
Defective induction of phenol glucuronidation by 3-methylcholanthrene in Gunn rats is due to the absence of a specific UDP-glucuronosyltransferase isoenzyme
-
Coughtrie M. W. H., Burchell B., Shepherd L. M., Bend J. R. Defective induction of phenol glucuronidation by 3-methylcholanthrene in Gunn rats is due to the absence of a specific UDP-glucuronosyltransferase isoenzyme. Mol. Pharmacol. 31:1987;585-591.
-
(1987)
Mol. Pharmacol.
, vol.31
, pp. 585-591
-
-
Coughtrie, M.W.H.1
Burchell, B.2
Shepherd, L.M.3
Bend, J.R.4
-
10
-
-
0025940578
-
Absence of phenolic glucuronidation and enhanced hydroxylation of diflunisal in the homozygous Gunn rat
-
Dickinson R. G., Verbeeck R. K., King A. R. Absence of phenolic glucuronidation and enhanced hydroxylation of diflunisal in the homozygous Gunn rat. Xenobiotica. 21:1991;1535-1546.
-
(1991)
Xenobiotica
, vol.21
, pp. 1535-1546
-
-
Dickinson, R.G.1
Verbeeck, R.K.2
King, A.R.3
-
11
-
-
84885370235
-
Studies on biological activity of cyclic imide compounds. Part II. Antimicrobial activity of 1-phenylpyrrolidine-2,5-diones and related compounds
-
Fujinami A., Ozaki T., Nodera K., Tanaka K. Studies on biological activity of cyclic imide compounds. Part II. Antimicrobial activity of 1-phenylpyrrolidine-2,5-diones and related compounds. Agric. Biol. Chem. 36:1972;318-323.
-
(1972)
Agric. Biol. Chem.
, vol.36
, pp. 318-323
-
-
Fujinami, A.1
Ozaki, T.2
Nodera, K.3
Tanaka, K.4
-
12
-
-
0001766925
-
Studies on biological activity of cyclic imide compounds. Part I. Antimicrobial activity of 3-phenyloxazolidine-2,4-diones and related compounds
-
Fujinami A., Ozaki T., Yamamoto S. Studies on biological activity of cyclic imide compounds. Part I. Antimicrobial activity of 3-phenyloxazolidine-2,4-diones and related compounds. Agric. Biol. Chem. 35:1971;1707-1719.
-
(1971)
Agric. Biol. Chem.
, vol.35
, pp. 1707-1719
-
-
Fujinami, A.1
Ozaki, T.2
Yamamoto, S.3
-
13
-
-
0026625313
-
Effects of microsomal enzyme inducers upon UDP-glucuronic acid concentration and UDP-glucuronosyltransferase activity in the rat intestine and liver
-
Goon D., Klaassen C. D. Effects of microsomal enzyme inducers upon UDP-glucuronic acid concentration and UDP-glucuronosyltransferase activity in the rat intestine and liver. Toxicol. Appl. Pharmacol. 115:1992;253-260.
-
(1992)
Toxicol. Appl. Pharmacol.
, vol.115
, pp. 253-260
-
-
Goon, D.1
Klaassen, C.D.2
-
14
-
-
0001130357
-
Hereditary acholuric jaundice in a new mutant strain of rats
-
Gunn C. H. Hereditary acholuric jaundice in a new mutant strain of rats. J. Hered. 29:1938;137-139.
-
(1938)
J. Hered.
, vol.29
, pp. 137-139
-
-
Gunn, C.H.1
-
16
-
-
0026608247
-
Nephrotoxic potential ofNN
-
Harvison P. J., Griffith R. J., Teets V. J., Nicoll D. W., Brown P. I., Rankin G. O. Nephrotoxic potential ofNN. Toxicol. Lett. 60:1992;221-226.
-
(1992)
Toxicol. Lett.
, vol.60
, pp. 221-226
-
-
Harvison, P.J.1
Griffith, R.J.2
Teets, V.J.3
Nicoll, D.W.4
Brown, P.I.5
Rankin, G.O.6
-
17
-
-
0019995539
-
Apparent intramolecular acyl migration of zomepirac glucuronide
-
Hasegawa J., Smith P. C., Benet L. Z. Apparent intramolecular acyl migration of zomepirac glucuronide. Drug Metab. Disp. 10:1982;469-473.
-
(1982)
Drug Metab. Disp.
, vol.10
, pp. 469-473
-
-
Hasegawa, J.1
Smith, P.C.2
Benet, L.Z.3
-
18
-
-
0000822335
-
Control of brown rot and transit rot of peaches with post-harvest fungicidal dips
-
Heaton J. B. Control of brown rot and transit rot of peaches with post-harvest fungicidal dips. Queensl. J. Agric. Anim. Sci. 37:1980;155-159.
-
(1980)
Queensl. J. Agric. Anim. Sci.
, vol.37
, pp. 155-159
-
-
Heaton, J.B.1
-
19
-
-
0029584536
-
Potential metabolism and cytotoxicity ofN
-
Henesey C. M., Harvison P. J. Potential metabolism and cytotoxicity ofN. Toxicology. 104:1995;9-16.
-
(1995)
Toxicology
, vol.104
, pp. 9-16
-
-
Henesey, C.M.1
Harvison, P.J.2
-
22
-
-
0023151214
-
Difference in the effects of phenobarbital and 3-methylcholanthrene treatment on subunit composition of hepatic glutathioneS
-
Igarashi T., Irokawa N., Ono S., Ohmori S., Ueno K., Kitagawa H., Satoh T. Difference in the effects of phenobarbital and 3-methylcholanthrene treatment on subunit composition of hepatic glutathioneS. Xenobiotica. 17:1987;127-137.
-
(1987)
Xenobiotica
, vol.17
, pp. 127-137
-
-
Igarashi, T.1
Irokawa, N.2
Ono, S.3
Ohmori, S.4
Ueno, K.5
Kitagawa, H.6
Satoh, T.7
-
23
-
-
0016219863
-
Effect ofN
-
Ito N., Sugihara S., Makiura S., Arai M., Hirao K., Denda A., Nishio O. Effect ofN. Gann. 65:1974;131-138.
-
(1974)
Gann
, vol.65
, pp. 131-138
-
-
Ito, N.1
Sugihara, S.2
Makiura, S.3
Arai, M.4
Hirao, K.5
Denda, A.6
Nishio, O.7
-
24
-
-
0029416888
-
Strain as a determinant factor in the differential responsiveness of rats to chemicals
-
Kacew S., Ruben Z., McConnell R.F. Strain as a determinant factor in the differential responsiveness of rats to chemicals. Toxicol. Pathol. 23:1995;701-714.
-
(1995)
Toxicol. Pathol.
, vol.23
, pp. 701-714
-
-
Kacew, S.1
Ruben, Z.2
McConnell, R.F.3
-
25
-
-
0027269444
-
Diclofenac covalent protein binding is dependent on acyl glucuronide formation and is inversely related to P450-mediated acute cell injury in cultured rat hepatocytes
-
Kretz-Rommel A., Boelsterili U. A. Diclofenac covalent protein binding is dependent on acyl glucuronide formation and is inversely related to P450-mediated acute cell injury in cultured rat hepatocytes. Toxicol. Appl. Pharmacol. 120:1993;155-161.
-
(1993)
Toxicol. Appl. Pharmacol.
, vol.120
, pp. 155-161
-
-
Kretz-Rommel, A.1
Boelsterili, U.A.2
-
26
-
-
0019954841
-
The cholestatic effect of harmol glucuronide in the rat. Prevention of harmol-induced cholestasis by increased formation of harmol sulfate
-
Krijgsheld K. R., Koster H. J., Scholtens E., Mulder G. J. The cholestatic effect of harmol glucuronide in the rat. Prevention of harmol-induced cholestasis by increased formation of harmol sulfate. J. Pharmacol. Exp. Ther. 221:1982;731-734.
-
(1982)
J. Pharmacol. Exp. Ther.
, vol.221
, pp. 731-734
-
-
Krijgsheld, K.R.1
Koster, H.J.2
Scholtens, E.3
Mulder, G.J.4
-
27
-
-
0023633158
-
Differential effects of phenobarbital on ester and ether glucuronidation of diflunisal in rats
-
Lin J. H., Chen I.-W., Ulm E. H., Duggan D. E. Differential effects of phenobarbital on ester and ether glucuronidation of diflunisal in rats. J. Pharmacol. Exp. Ther. 242:1987;1013-1018.
-
(1987)
J. Pharmacol. Exp. Ther.
, vol.242
, pp. 1013-1018
-
-
Lin, J.H.1
Chen, I.-W.2
Ulm, E.H.3
Duggan, D.E.4
-
28
-
-
0025037473
-
Glucuronidation of 2-arylpropionic acids pirprofen, flurbiprofen, and ibuprofen by liver microsomes
-
Magdalou J., Chajes V., Lafaurie C., Siest G. Glucuronidation of 2-arylpropionic acids pirprofen, flurbiprofen, and ibuprofen by liver microsomes. Drug Metab. Disp. 18:1990;692-697.
-
(1990)
Drug Metab. Disp.
, vol.18
, pp. 692-697
-
-
Magdalou, J.1
Chajes, V.2
Lafaurie, C.3
Siest, G.4
-
29
-
-
0014525447
-
Nature of the urinary concentrating defect in the Gunn strain of rat
-
Martinez-Maldonado M., Suki W. N., Schenker S. Nature of the urinary concentrating defect in the Gunn strain of rat. Am. J. Physiol. 216:1969;1386-1391.
-
(1969)
Am. J. Physiol.
, vol.216
, pp. 1386-1391
-
-
Martinez-Maldonado, M.1
Suki, W.N.2
Schenker, S.3
-
30
-
-
0029790316
-
Reactivity of mefenamic acid 1-Oin vitroex vivo.
-
McGurk K. A., Remmel R. P., Hosagrahara V. P., Tosh D., Burchell B. Reactivity of mefenamic acid 1-Oin vitroex vivo. Drug Metab. Disp. 24:1996;842-849.
-
(1996)
Drug Metab. Disp.
, vol.24
, pp. 842-849
-
-
McGurk, K.A.1
Remmel, R.P.2
Hosagrahara, V.P.3
Tosh, D.4
Burchell, B.5
-
31
-
-
0026642306
-
Glucuronidation and its role in regulation of biological activity of durgs
-
Mulder G. J. Glucuronidation and its role in regulation of biological activity of durgs. Annu. Rev. Pharmacol. Toxicol. 32:1992;25-49.
-
(1992)
Annu. Rev. Pharmacol. Toxicol.
, vol.32
, pp. 25-49
-
-
Mulder, G.J.1
-
37
-
-
0022523365
-
Strain-related susceptibility to nephrotoxicity induced by aspirin and phenylbutazone in rats
-
Owen R. A., Heywood R. Strain-related susceptibility to nephrotoxicity induced by aspirin and phenylbutazone in rats. Toxicol. Pathol. 14:1986;242-246.
-
(1986)
Toxicol. Pathol.
, vol.14
, pp. 242-246
-
-
Owen, R.A.1
Heywood, R.2
-
38
-
-
0021368690
-
Rat liver glutathioneSS
-
Pickett C. B., Telakowski-Hopkins C. A., Ding G. J.-F., Argenbright L., Lu A. Y.-H. Rat liver glutathioneSS. J. Biol. Chem. 259:1984;5182-5188.
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 5182-5188
-
-
Pickett, C.B.1
Telakowski-Hopkins, C.A.2
Ding, G.J.-F.3
Argenbright, L.4
Lu, A.Y.-H.5
-
39
-
-
0020065532
-
Nephrotoxicity following acute administration ofN
-
Rankin G. O. Nephrotoxicity following acute administration ofN. Toxicology. 23:1982;21-31.
-
(1982)
Toxicology
, vol.23
, pp. 21-31
-
-
Rankin, G.O.1
-
41
-
-
74049087036
-
Effects of chloramphenicol, dehydroepiandrosterone (DHEA) and 2,6-dichloro-4-nitrophenol(DCNP) onN
-
Rankin G. O., Hong S. K., Dial L. D., Anestis D. K. Effects of chloramphenicol, dehydroepiandrosterone (DHEA) and 2,6-dichloro-4-nitrophenol(DCNP) onN. Toxicologist. 30:1996;303.
-
(1996)
Toxicologist
, vol.30
, pp. 303
-
-
Rankin, G.O.1
Hong, S.K.2
Dial, L.D.3
Anestis, D.K.4
-
42
-
-
0345365550
-
Effect of inhibitors of glucuronide conjugation onN
-
Rankin G. O., Hong S. K., Valentovic M. A., Anestis D. K., Dial L. D., Ball J. G. Effect of inhibitors of glucuronide conjugation onN. ISSX Proc. 8:1995;183.
-
(1995)
ISSX Proc.
, vol.8
, pp. 183
-
-
Rankin, G.O.1
Hong, S.K.2
Valentovic, M.A.3
Anestis, D.K.4
Dial, L.D.5
Ball, J.G.6
-
43
-
-
0025764689
-
-
Rankin G. O., Shih H. C., Teets V. J., Yang D. J., Nicoll D. W., Brown P. I. N. Toxicology. 68:1991a;307-325.
-
(1991)
N. Toxicology
, vol.68
, pp. 307-325
-
-
Rankin, G.O.1
Shih, H.C.2
Teets, V.J.3
Yang, D.J.4
Nicoll, D.W.5
Brown, P.I.6
-
44
-
-
0024272653
-
Nephrotoxicity ofNin vivoin vitro.
-
Rankin G. O., Shih H. C., Yang D. J., Richmond C. D., Teets V. J., Brown P. I. Nephrotoxicity ofNin vivoin vitro. Toxicol. Appl. Pharmacol. 96:1988;405-416.
-
(1988)
Toxicol. Appl. Pharmacol.
, vol.96
, pp. 405-416
-
-
Rankin, G.O.1
Shih, H.C.2
Yang, D.J.3
Richmond, C.D.4
Teets, V.J.5
Brown, P.I.6
-
48
-
-
0023276308
-
Effect of microsomal enzyme activity modulation onN
-
Rankin G. O., Yang D. J., Richmond C. D., Teets V. J., Wang R. T., Brown P. I. Effect of microsomal enzyme activity modulation onN. Toxicology. 45:1987a;269-289.
-
(1987)
Toxicology
, vol.45
, pp. 269-289
-
-
Rankin, G.O.1
Yang, D.J.2
Richmond, C.D.3
Teets, V.J.4
Wang, R.T.5
Brown, P.I.6
-
50
-
-
0023272569
-
The effect of probenecid on acuteN
-
Rankin G. O., Yang D. J., Teets V. J., Lo H. H., Brown P. I. The effect of probenecid on acuteN. Toxicology. 44:1987b;181-192.
-
(1987)
Toxicology
, vol.44
, pp. 181-192
-
-
Rankin, G.O.1
Yang, D.J.2
Teets, V.J.3
Lo, H.H.4
Brown, P.I.5
-
51
-
-
0026642917
-
Probenecid-impaired biliary excretion of acetaminophen glucuronide and sulfate in the rat
-
Savina P. M., Brouwer K. L. R. Probenecid-impaired biliary excretion of acetaminophen glucuronide and sulfate in the rat. Drug Metab. Dispos. 20:1992;496-501.
-
(1992)
Drug Metab. Dispos.
, vol.20
, pp. 496-501
-
-
Savina, P.M.1
Brouwer, K.L.R.2
-
52
-
-
0021951417
-
Congenital jaundice in rats due to the absence of hepatic bilirubin UDP-glucuronosyltransferase enzyme protein
-
Scragg I., Celier C., Burchell B. Congenital jaundice in rats due to the absence of hepatic bilirubin UDP-glucuronosyltransferase enzyme protein. FEBS Lett. 183:1985;37-42.
-
(1985)
FEBS Lett.
, vol.183
, pp. 37-42
-
-
Scragg, I.1
Celier, C.2
Burchell, B.3
-
53
-
-
0000672129
-
Convenient synthesis ofN
-
Shih H., Rankin G. O. Convenient synthesis ofN. Synthesis. 11:1989;866-867.
-
(1989)
Synthesis
, vol.11
, pp. 866-867
-
-
Shih, H.1
Rankin, G.O.2
-
54
-
-
0017136054
-
Combination effect of citrinin and other chemicals on rat kidney tumorigenesis
-
Shinohara Y., Arai M., Hirao K., Sugihara S., Nakanishi K., Tsunoda H., Ito N. Combination effect of citrinin and other chemicals on rat kidney tumorigenesis. Gann. 67:1976;147-155.
-
(1976)
Gann
, vol.67
, pp. 147-155
-
-
Shinohara, Y.1
Arai, M.2
Hirao, K.3
Sugihara, S.4
Nakanishi, K.5
Tsunoda, H.6
Ito, N.7
-
55
-
-
0017750504
-
Effect ofN
-
Shinohara Y., Miyata Y., Murasaki G., Nakanishi K., Takashi Y., Ito N. Effect ofN. Gann. 68:1977;397-404.
-
(1977)
Gann
, vol.68
, pp. 397-404
-
-
Shinohara, Y.1
Miyata, Y.2
Murasaki, G.3
Nakanishi, K.4
Takashi, Y.5
Ito, N.6
-
56
-
-
0026532030
-
Acyl glucuronides revisited: Is the glucuronidation process a toxification as well as a detoxification mechanism
-
Spahn-Langguth H., Benet L. Z. Acyl glucuronides revisited: Is the glucuronidation process a toxification as well as a detoxification mechanism. Drug Metab. Rev. 24:1992;5-48.
-
(1992)
Drug Metab. Rev.
, vol.24
, pp. 5-48
-
-
Spahn-Langguth, H.1
Benet, L.Z.2
-
57
-
-
0016786166
-
Pathologic analysis of chemical nephritis in rats induced byN
-
Sugihara S., Shinohara Y., Miyata Y., Inoue K., Ito N. Pathologic analysis of chemical nephritis in rats induced byN. Lab. Invest. 33:1975;219-230.
-
(1975)
Lab. Invest.
, vol.33
, pp. 219-230
-
-
Sugihara, S.1
Shinohara, Y.2
Miyata, Y.3
Inoue, K.4
Ito, N.5
-
58
-
-
0018569916
-
Quantitative structure-activity relationships of antifungalNN
-
Takayama C., Fujinami A. Quantitative structure-activity relationships of antifungalNN. Pestic. Biochem. Physiol. 12:1979;163-171.
-
(1979)
Pestic. Biochem. Physiol.
, vol.12
, pp. 163-171
-
-
Takayama, C.1
Fujinami, A.2
-
60
-
-
0025977714
-
Hepatic clearance and biliary secretory rate maximum of taurocholate in the recirculating and single pass isolated perfused rat liver. Effects of the cholestatic agent, estradiol 17′-β(β-d
-
Vore M., Durham S., Yeh S., Ganguly T. Hepatic clearance and biliary secretory rate maximum of taurocholate in the recirculating and single pass isolated perfused rat liver. Effects of the cholestatic agent, estradiol 17′-β(β-d. Biochem. Pharmacol. 41:1991;431-437.
-
(1991)
Biochem. Pharmacol.
, vol.41
, pp. 431-437
-
-
Vore, M.1
Durham, S.2
Yeh, S.3
Ganguly, T.4
-
62
-
-
0020431254
-
Induction of UDP-glucuronosyltransferase activities in Gunn, heterozygous, and Wistar rat livers by pregnenolone-16Ó-carbonitrile
-
Watkins J. B., Klaassen C. D. Induction of UDP-glucuronosyltransferase activities in Gunn, heterozygous, and Wistar rat livers by pregnenolone-16Ó-carbonitrile. Drug Metab. Disp. 10:1982;590-594.
-
(1982)
Drug Metab. Disp.
, vol.10
, pp. 590-594
-
-
Watkins, J.B.1
Klaassen, C.D.2
-
63
-
-
0022353892
-
Effect of succinimide ring modification onN
-
Yang D. J., Richmond C. D., Teets V. J., Brown P. I., Rankin G. O. Effect of succinimide ring modification onN. Toxicology. 37:1985;65-77.
-
(1985)
Toxicology
, vol.37
, pp. 65-77
-
-
Yang, D.J.1
Richmond, C.D.2
Teets, V.J.3
Brown, P.I.4
Rankin, G.O.5
-
64
-
-
0023375047
-
Role of glutathione in acuteN
-
Yang D. J., Teets V. J., Bolton B., Brown P. I., Rankin G. O. Role of glutathione in acuteN. Toxicology. 45:1987;25-44.
-
(1987)
Toxicology
, vol.45
, pp. 25-44
-
-
Yang, D.J.1
Teets, V.J.2
Bolton, B.3
Brown, P.I.4
Rankin, G.O.5
|