Treatment of refractory chronic depression and dysthymia with high-dose thyroxine

Biological Psychiatry

Volumn 45, Issue 2, 1999, Pages 229-233

  Rudas, Stephan ^a   Schmitz, Margot ^a   Pichler, Philipp ^a   Baumgartner, Andreas ^b  

^a Comm Mental Hlth Service of Vienna ^*  (Austria)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Chronic depression; Dysthymia; High dose thyroxine; Therapy resistant depression

Indexed keywords

ALPRAZOLAM; AMITRIPTYLINE; ANTIDEPRESSANT AGENT; CARBAMAZEPINE; CITALOPRAM; CLOMIPRAMINE; DIBENZEPIN; DOXEPIN; FLUOXETINE; HALOPERIDOL; LITHIUM; MAPROTILINE; MIANSERIN; NEUROLEPTIC AGENT; PAROXETINE; THYROXINE; TRANYLCYPROMINE;

ADULT; AGED; ANXIETY NEUROSIS; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; DEPRESSION; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG RESPONSE; DYSTHYMIA; FEMALE; FOLLOW UP; HORMONAL THERAPY; HUMAN; HYPERTENSION; MALE; PRIORITY JOURNAL; RESTLESSNESS; SWEATING; TREATMENT FAILURE; TREATMENT OUTCOME; TREMOR;

ADULT; AGED; ANTIDEPRESSIVE AGENTS; CHRONIC DISEASE; DEPRESSIVE DISORDER; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; DRUG RESISTANCE; DYSTHYMIC DISORDER; FEMALE; HUMANS; MALE; MIDDLE AGED; THYROXINE;

EID: 0033556516     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3223(98)00033-X     Document Type: Article

References (14)

1. Diagnostic and Statistical Manual of Mental Disorders, 3rd ed rev. 1987;American Psychiatric Press, Washington, DC.
2. Bauer M.S., Whybrow P.C. Rapid cycling bipolar affective disorders II. Treatment of refractory rapid cycling with high-dose levothyroxine: A preliminary study . Arch Gen Psychiatry. 47:1990;435-440.
3. Baumgartner A., Gräf K.J., Kürten I., Meinhold H. The hypothalamic-pituitary-thyroid axis in psychiatric patients and healthy subjects Parts 1-4 . Psychiatry Res. 24:1988;271-332.
4. Baumgartner A., Bauer M., Hellweg R. Treatment of intractable non-rapid cycling bipolar affective disorder with high-dose thyroxine An open clinical trial . Neuropsychopharmacology. 10:1994;183-189.
5. Baumgartner A., Dubeyko M., Campos-Barros A., Eravci M., Meinhold H. Subchronic administration of fluoxetine to rats affects triiodothyronine production and deiodination in regions of the cortex and the limbic forebrain. Brain Res. 635:1994;68-74.
6. Campos-Barros A., Meinhold H., Stula M., Müller F., Köhler R., Eravci M., et al. The influence of desipramine on thyroid hormone metabolism in rat brain. J Pharmacol Exp Ther. 268:1994;1143-1152.
7. Crantz F.R., Silva J.E., Larsen P.R. Analysis of the sources and quantity of 3,5,3′-iodothyronine specifically bound to nuclear receptors in rat cerebral cortex and cerebellum. Endocrinology. 110:1982;367-375.
8. Hall R.C.W., Stickney S., Beresford T.P. Endocrine disease and behavior. Integr Psychiatry. 4:1986;122-135.
9. Hurowitz G.I., Liebowitz M.R. Antidepressant-induced rapid cycling Six case reports . J Clin Psychopharmacol. 13:1993;52-56.
10. Joffe R.T., Singer W. Comparison of triiodothyronine and thyronine in the potentiation of tricyclic antidepressants. Psychiatry Res. 32:1990;241-251.
11. Leibow D. L-thyroxine for rapid-cycling bipolar illness. Am J Psychiatry. 140:1983;1255-1256.
12. Nierenberg A.A., Amsterdam J.D. Treatment-resistant depression Definition and treatment approaches . J Clin Psychiatry. 51:(suppl 6):1990;39-47.
13. Prange A.J. Jr, Wilson I.C., Rabon A.M., Lipton M.A. Enhancement of imipramine antidepressant activity by thyroid hormone. Am J Psychiatry. 126:1969;457-469.
14. Stancer H.C., Persad E. Treatment of intractable rapid-cycling manic-depressive disorder with levothyroxine. Arch Gen Psychiatry. 39:1982;311-312.