Desensitization of G-protein-coupled receptors: Agonist-induced phosphorylation of the chemoattractant receptor cAR1 lowers its intrinsic affinity for cAMP

Journal of Biological Chemistry

Volumn 274, Issue 3, 1999, Pages 1440-1448

  Xiao, Zhan ^a   Yao, Yihong ^a   Long, Yu ^a   Devreotes, Peter ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; GUANINE NUCLEOTIDE BINDING PROTEIN;

ARTICLE; CHEMOTAXIS; DICTYOSTELIUM DISCOIDEUM; IMMUNE RESPONSE; INTERNALIZATION; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; RECEPTOR AFFINITY; SMELLING; VISION;

ALANINE; AMINO ACID SUBSTITUTION; ANIMALS; CELL LINE; CHOLIC ACIDS; CHROMATOGRAPHY, AFFINITY; CYCLIC AMP; DETERGENTS; DICTYOSTELIUM; GLYCINE; GTP-BINDING PROTEINS; KINETICS; LIGANDS; NICKEL; PHOSPHORYLATION; RECEPTORS, CYCLIC AMP;

DICTYOSTELIUM DISCOIDEUM;

EID: 0033556437     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.3.1440     Document Type: Article

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