Preparation of cyrstalline p-nitrobenzyl 2-hydroxymethyl carbapenem as a key intermediate for the anti-MRS carbapenem L-786,392

Tetrahedron Letters

Volumn 40, Issue 3, 1999, Pages 427-430

  Yasuda, Nobuyoshi ^a   Yang, Chunhua ^a   Wells, Kenneth M ^a   Jensen, Mark S ^a   Hughes, David L ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Carbapenems; Coupling reactions; Tin compounds

Indexed keywords

CARBAPENEM; CARBAPENEM DERIVATIVE; L 786392; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL INFECTION; DRUG PURIFICATION; DRUG STABILITY; DRUG SYNTHESIS; ENTEROCOCCUS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS;

BACTERIA (MICROORGANISMS); ENTEROCOCCUS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS AUREUS;

EID: 0033556115     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)02393-4     Document Type: Article

References (16)

1. Blizzard, TA, Ratcliffe RW, Wilkening RR. US 5,756,725.
2. Wilkening RR, Ratcriffe RW, Wildonger KJ, Waddell ST, Santorelli GM, Parker DL, Morgan J, Blizzard TA, Cama LD, Sun W, Leone JF, Hammond ML. The 38th Interscience Conference on Antimicrobial Agents and Chemotherapy, Paper #F-32, San Diego, CA, September 1998.
3. Wilkening RR, Ratcliffe RW, Cama LD, Wildonger KJ, Dykstra KD, Dininno FP, Blizzard TA, Hammond ML. ibid, Paper #F-33, San Diego, CA, September 1998.
4. Dininno F, Chen HY, Dykstra KD, Hammond ML. ibid, Paper #F-34, San Diego, CA, September 1998.
5. Uyeo S, Itani H. Tetrahedron Lett. 1994; 35: 4377-4378.
6. Schmitt SM, Salzmann TN, Shih DH, Christensen BG. J. Antibiot. 1988; 41: 780-787.
7. Imuta M, Itani H, Ona H, Hamada Y, Uyeo S, Yoshida T. Chem. Pharm. Bull. 1991; 39: 663-671.
8. Imuta M, Itani H, Ona H, Konoike T, Uyeo S, Kimura Y, Miwa H, Matsuura S, Yoshida T. Chem. Pharm. Bull. 1991; 39: 672-678.
9. Imuta M, Itani H, Nishi K, Ona H, Uyeo S, Kimura Y. Bioorg. Med. Chem. Lett. 1993; 3: 2199-2204.
10. Corraz AJ, Dax SL, Dunlap NK, Georgopapadakou NH, Keith DD, Pruess DL, Rossman PL, Then R, Unowsky J, Wei C-C. J. Med. Chem. 1992; 35: 1828-1839.
11. Hu XE, Demuth TPJr. J. Org. Chem. 1998; 63: 1719-1723.
12. Yang C, Yasuda N. Bioorg. Med. Chem. Lett. 1998; 8: 255-256.
13. Kosugi M, Sumiya T, Ohhashi K, Sano H, Migita T. Chem. Lett. 1985: 997-998.
14. Yasuda N, Huffman MA, Ho G-J, Xavier LC, Yang C, Emerson KM, Tsay F-R, Li Y, Kress MH, Rieger DL, Karady S, Sohar P, Abramson NL, DeCamp AE, Mathre DJ, Douglas AW, Dolling U-H, Grabowski EJJ, Reider PJ. J. Org. Chem. 1998; 63: 5438-5446.
15. Farina V, Krishnan B, Marshall DR, Roth GP. J. Org. Chem. 1993; 58: 5434-5444.
16. Allred GD, Liebeskind LS. J. Am. Chem. Soc. 1996; 118: 2748-2749.